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Project

Remming van guanylyl cyclase C (GC‐C) activiteit voor het behandelen van secretoire diarree

Output en outcomes

Code

179P7812

Looptijd

01-02-2011 → 31-10-2012

Financiering

Privémiddelen via IWT/VLAIO

Promotor

Eric Cox

Onderzoeksdisciplines

Natural sciences
- Animal biology
Medical and health sciences
- Immunology
- Immunology
- Microbiology
- Public health care
- Public health sciences
- Public health services
- Immunology
Agricultural and food sciences
- Veterinary medicine
- Other veterinary sciences
- Other agricultural and food sciences

Trefwoorden

ETEC reizigers diarree GC-C inhibitoren

Projectomschrijving

De hypothese die in dit project getoetst zal worden is, dat de door STa geïnduceerde vloeistof

secretie in de darm geremd kan worden via de remming van de GC‐C receptor activiteit. Het

tweede doel is minstens twee nieuwe GC‐C inhibitoren te synthetiseren waarvoor in vivo

activiteit aangetoond kan worden.

English

Dutch

English

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