Inhibition of guanylyl cyclase C (GC-C) activity for the treatment of secretory diarrhea

01 February 2011 → 31 October 2012
Private funding via IWT/VLAIO
Research disciplines
  • Natural sciences
    • Animal biology
  • Medical and health sciences
    • Immunology
    • Immunology
    • Microbiology
    • Public health care
    • Public health sciences
    • Public health services
    • Immunology
  • Agricultural and food sciences
    • Veterinary medicine
    • Other veterinary sciences
    • Other agricultural, veterinary and food sciences
ETEC traveler's diarrhea GC-C inhibitors
Project description

The hypothesis will be tested in this project is that the induced fluid STa

may be due to the inhibition of the GC-C receptor activity. secretion in the intestine inhibited the

second objective is to synthesize at least for which in vivo, two new GC-C inhibitors

can be. activity demonstrated