Dissecting stromal-cancer cell interactions at the perivascular niche to detect and intercept the early metastatic process.

Exploring the biology and application of systemically circulating bacterial extracellular vesicles in cancer patients.

ModulatIng Cancer therapy RespOnse using Bacterial Extracellular nanovesicles

Doctoral project Sofie Van Dorpe

Exploring bacterial extracellular vesicles in liquid biopsies from cancer patients

Exploring bacterial extracellular vesicles in liquid biopsies from cancer patients

Exploring bacterial extracellular vesicles in liquid biopsies from cancer patients

Functions of extracellular vesicles in cancer biology

Impact of cancer-associated fibroblasts and their secretome on immune cross-talk upon irradiation

Rigor and standardization in extracellular vesicle research to enable clinical translation

The role of bacterial extracellular vesicles in cancer

The role of EV in HIV infection

The study of bacterial extracellular vesicle-mediated immune responses in cancer

The study of bacterial extracellular vesicles in anti-tumour responses

Trash or Treasure Biogenesis and Function of Extracellular Vesicle subsets in Hormone-Positive Breast Cancer

Doctoral project Eva Blondeel

Doctoral project Glenn Vergauwen

Doctoral project Suzanne Fischer

The Plasticity of Cancer- Associated Fibroblasts

Analyzing circulating bacterial extracellular vesicles in cancer patients to identify their composition and biomarker potential.

Analyzing the immunobiological function of circulating bacterial extracellular vesicles in cancer patients

Bacterial EV - BEV

BOF-TT-professorship in cancer and mechanisms of metastasis

Detection and validation of EV-associated molecular patterns to diagnose early stage ovarian cancer

Development of tools to aid rigor and standardization in extracellular vesicle research.

Direct, rapid and sensitive sensing in body fluids to enable a fine-grained biomarker view on extracellular vesicles

Elusive confounding factors: how transparent methodology fuels the discovery of extracellular vesicle-associated cargo and functions.

Exploring the biology of bacterial extracellular vesicles in human biofluids.

Extracellular vesicle (EV) transport across the brain barriers: from mechanistic and biological insights towards strategies for delivery of therapeutics to the brain.

Extracellular vesicles: from technology to biomedical application

Function and biogenesis of extracellular vesicle subsets in cancer

Natural variations in extracellular vesicles subpopulations and RNA composition

Strategies against persistent HIV-1 reservoirs

Studying biomolecular corona-dependency of (sub)cellular interactions using patient-derived tumor models to guide ev-based therapeutic development.

Training in Extracellular Vesicles: for benefit in Health and Disease

Unravelling uptake and function of systemic bacterial extracellular vesicles in cancer patients using clinically relevant in vitro, ex vivo and in vivo models.

Cancer cell-derived exosomes and their role in the tumor ecosystem

Exosomal miRNAs as a biomarker for early targeted therapy response in advanced triple negative breast cancer

Extracellular vesicles as non-invasive biomarkers for assessing the competence of human embryos to implant and establish a clinical pregnancy

FullPicture: Combining Spectral Flow Cytometry with High-Speed Cell Imaging to enable comprehensive profiling of plant and animal cells and their components in real time.

Identification of anti-FOLR1 VHHs as novel candidates for FOLR1-targeted (brain) tumor imaging and anti-cancer therapy.

Long noncoding RNAs in cancer: deciphering the functional role of the dark matter of the human cancer genome

Selection of human embryos for transfer at day 3 or at day 5 of culture: an informed decision based on extracellular vesicle content from media conditioned by single embryos

BOF-TT-professorship in cancer and mechanisms of metastasis

Exosomes: nanomaps for metastatic niche formation

CanIFreeze project: A tool to increase genetic diversity in Belgian pedigree dogs.

Does the altered rumen microbiome of eco-friendlier cows cause more metabolic stress?

Long-term effects of signaling molecules during bovine oocyte maturation in vitro: from research to clinical practice