Research Explorer

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Researcher

An Hendrix

139 Results

2022

Biomarkers in gynecological cancer : the potential of tumor infiltrating immune cells and circulating extracellular vesicles

Lien LippensHannelore DenysAn HendrixKatrien Vandecasteele

Hatching is modulated by microRNA-378a-3p derived from extracellular vesicles secreted by blastocysts

Krishna PavaniTim MeeseOsvaldo Américo Bogado PascottiniXiaoyuan LinLuc PeelmanFilip Van NieuwerburghDieter DeforceAnnekatrien BoelBjörn HeindryckxKelly TillemanAnn Van SoomBart GadellaAn HendrixKatrien Smits

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrins are enriched on aberrantly fucosylated tumour‐derived urinary extracellular vesicles

Bert DhondtAn Hendrix

A2 Journal Article in JOURNAL OF EXTRACELLULAR BIOLOGY

Metastasized orthotopic patient-derived xenografts as preclinical model to guide therapeutic decision making in soft tissue sarcoma patients

Suzanne FischerElly De VlieghereDavid CreytensOlivier De WeverAn HendrixLore LapeireGwen Sys

Pembrolizumab, radiotherapy, and an immunomodulatory five-drug cocktail in pretreated patients with persistent, recurrent, or metastatic cervical or endometrial carcinoma : results of the phase II PRIMMO study

Emiel De JaeghereLien LippensEline NaertAn HendrixOlivier De WeverKoen Van de VijverKatrien VandecasteeleHannelore Denys

A1 Journal Article in CANCER IMMUNOLOGY IMMUNOTHERAPY

Removal of platelets from blood plasma to improve the quality of extracellular vesicle research

Bert DhondtAn Hendrix

A1 Journal Article in JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Safety of pre- or postoperative accelerated radiotherapy in 5 fractions : a randomized pilot trial

Vincent VakaetKoen Van de VijverEline NaertWilfried De NeveJo Van DorpeAn HendrixMenekse GOKERHerman DepypereRudy Van den BroeckePieter De VisschereGeert BraemsKatrien VandecasteeleHannelore DenysLiv Veldeman

A1 Journal Article in BREAST

2021

Accelerated radiotherapy in 5 fractions in breast cancer patients : physician-assessed toxicity and patient-related outcomes

Hans Van HulleLiv VeldemanHannelore DenysAn Hendrix

Circulating bacterial vesicles : from discovery towards clinical application

Joeri TulkensAn HendrixJo Vandesompele

Extracellular vesicles from follicular and ampullary fluid isolated by density gradient ultracentrifugation improve bovine embryo development and quality

Nima AzariDolatabadHadi AtashiAnnelies RaesPetra Van DammeAn HendrixOsvaldo Américo Bogado PascottiniAnn Van SoomKrishna Pavani

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

FO‐SPR biosensor calibrated with recombinant extracellular vesicles enables specific and sensitive detection directly in complex matrices

Edward GeeurickxDelphine De SutterSven EyckermanAn Hendrix

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

Importance of extracellular vesicle secretion at the blood-cerebrospinal fluid interface in the pathogenesis of Alzheimer’s disease

Charysse VandendriesscheCaroline Van CauwenbergheMarjana BrkicMarie PauwelsNele PlehiersArnout BruggemanPieter DujardinGriet Van ImschootElien Van WonterghemAn HendrixFemke BaekeRiet De RyckeKris GevaertRoosmarijn Vandenbroucke

A1 Journal Article in ACTA NEUROPATHOLOGICA COMMUNICATIONS

MISpheroID : a knowledgebase and transparency tool for minimum information in spheroid identity

Arne PeirsmanEva BlondeelJasper AnckaertDominique AudenaertTom BoterbergElly De VlieghereSandor DedeyneHerman DepypereRuslan DmitrievSuzanne FischerVera GoossensAn HendrixSebastiaan MaesChristophe MangodtPieter MestdaghCláudio PinheiroGwen SysJoeri TulkensJo VandesompeleGlenn WagemansNurten YigitPhillip BlondeelOlivier De Wever

A1 Journal Article in NATURE METHODS

Patient-derived cell lines and xenografts from sarcoma patients as models for therapeutic decision making

Suzanne FischerDavid CreytensGwen SysLore LapeireAn HendrixOlivier De Wever

Pembrolizumab, SBRT, and immunomodulation for recurrent and/or refractory cervical or endometrial carcinoma

Emiel De JaeghereLien LippensAn HendrixEline NaertKatrien VandecasteeleHannelore Denys

Recombinant extracellular vesicles as biological reference material for method development, data normalization and assessment of (pre-)analytical variables

Edward GeeurickxLien LippensBruno De GeestOlivier De WeverAn Hendrix

A1 Journal Article in NATURE PROTOCOLS

Robust sequential biophysical fractionation of blood plasma to study variations in the biomolecular landscape of systemically circulating extracellular vesicles across clinical conditions

Glenn VergauwenJoeri TulkensCláudio PinheiroFrancisco Avila CobosSandor DedeyneMarie-Angélique De ScheerderLinos VandekerckhoveFrancis ImpensGeert BraemsKris GevaertPieter MestdaghJo VandesompeleHannelore DenysOlivier De WeverAn Hendrix

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

The nature of blood(y) extracellular vesicles

Editorial material

2020

Analyzing bacterial extracellular vesicles in human body fluids by orthogonal biophysical separation and biochemical characterization

Joeri TulkensOlivier De WeverAn Hendrix

A1 Journal Article in NATURE PROTOCOLS

Development and application of a biological reference material for extracellular vesicle research

Edward GeeurickxOlivier De WeverAn Hendrix

Feasibility of mechanical extrusion to coat nanoparticles with extracellular vesicle membranes

Jan Van DeunQuentin RouxSarah DevilleThibaut Van AckerFrank VanhaeckeBruno De GeestOlivier De WeverAn Hendrix

A1 Journal Article in CELLS

Feasibility study on pre or postoperative accelerated radiotherapy (POP-ART) in breast cancer patients

Hans Van HulleVincent VakaetGiselle PostChristel MontenAn HendrixKoen Van de VijverJo Van DorpePieter De VisschereGeert BraemsKatrien VandecasteeleHannelore DenysWilfried De NeveLiv Veldeman

A2 Journal Article in PILOT AND FEASIBILITY STUDIES

Immunologic impact of chemoradiation in cervical cancer and how immune cell infiltration could lead towards personalized treatment

Lien LippensMieke Van BockstalEmiel De JaegherePhilippe TummersAmin MakarSofie De GeyterKoen Van de VijverAn HendrixKatrien VandecasteeleHannelore Denys

A1 Journal Article in International Journal of Cancer

Increased levels of systemic LPS-positive bacterial extracellular vesicles in patients with intestinal barrier dysfunction

Joeri TulkensGlenn VergauwenJan Van DeunEdward GeeurickxBert DhondtLien LippensMarie-Angélique De ScheerderBruno De GeestKatrien VandecasteeleDebby LaukensLinos VandekerckhoveHannelore DenysJo VandesompeleOlivier De WeverAn Hendrix

A1 Journal Article in GUT

MIFlowCyt-EV : a framework for standardized reporting of extracellular vesicle flow cytometry experiments

An HendrixOlivier De Wever

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

Performance assessment of total RNA sequencing of human biofluids and extracellular vesicles

Celine EveraertHetty HelsmoortelAnneleen DecockEva HulstaertRuben Van PaemelKimberly VerniersJustine NuytensJasper AnckaertJoeri TulkensBert DhondtAn HendrixPieter MestdaghJo Vandesompele

Preparation of multi-omics grade extracellular vesicles by density-based fractionation of urine

Bert DhondtNicolaas LumenOlivier De WeverAn Hendrix

A2 Journal Article in STAR PROTOCOLS

Substantial performance differences among RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control study-important considerations for liquid biopsies

Anneleen DecockJasper AnckaertCeline EveraertJustine NuytensAn HendrixJo VandesompelePieter MestdaghBert DhondtRuben Van PaemelKimberly VerniersNurten YigitKathleen SchoofsAnnelien MorlionJill DeleuEva HulstaertFrancisco Avila CobosEveline Vanden EyndeHetty HelsmoortelOlivier De WeverAnnouck Philippron

Targets, pitfalls and reference materials for liquid biopsy tests in cancer diagnostics

Edward GeeurickxAn Hendrix

A1 Journal Article in MOLECULAR ASPECTS OF MEDICINE

The EV-TRACK summary add-on: integration of experimental information in databases to ensure comprehensive interpretation of biological knowledge on extracellular vesicles

Quentin RouxSandor DedeyneAn Hendrix

Editorial material

The separation and characterization of extracellular vesicles from medium conditioned by bovine embryos

Krishna PavaniXiaoyuan LinWim Van Den BroeckLiesbeth CouckLuc PeelmanAn HendrixAnn Van Soom

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Towards defining reference materials for measuring extracellular vesicle refractive index, epitope abundance, size and concentration

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

Unravelling the proteomic landscape of extracellular vesicles in prostate cancer by density-based fractionation of urine

Bert DhondtEdward GeeurickxJoeri TulkensJan Van DeunGlenn VergauwenLien LippensPiet OstNicolaas LumenOlivier De WeverAn Hendrix

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

2019

A supporting ecosystem to mature extracellular vesicles into clinical application

Olivier De WeverAn Hendrix

A1 Journal Article in EMBO JOURNAL

Considerations towards a roadmap for collection, handling and storage of blood extracellular vesicles

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

Dramatic differences in RNA purification kit performance in the extracellular RNA quality control study : important considerations for liquid biopsies

Annelien MorlionJasper AnckaertFrancisco Avila CobosAnneleen DecockOlivier De WeverBert DhondtCeline EveraertHetty HelsmoortelAn HendrixEva HulstaertPieter MestdaghJustine NuytensAnnouck PhilippronEveline Vanden EyndeJo VandesompeleRuben Van PaemelKimberly VerniersNurten Yigit

Dramatic differences in RNA purification kit performance in the extracellular RNA quality control study : important considerations for liquid biopsies

Annelien MorlionJasper AnckaertFrancisco Avila CobosAnneleen DecockOlivier De WeverBert DhondtCeline EveraertHetty HelsmoortelAn HendrixEva HulstaertPieter MestdaghJustine NuytensAnnouck PhilippronEveline Vanden EyndeJo VandesompeleRuben Van PaemelKimberly VerniersNurten Yigit

Establishment of 6 novel patient-derived sarcoma cell lines and 1 patient-derived carcinosarcoma cell line

Suzanne FischerDavid CreytensLore LapeireAn HendrixPiet PattynGwen Sys

Evaluating the impact of RNA purification kit and blood collection tube in the extracellular RNA quality control study : important considerations for liquid biopsies

Annelien MorlionJasper AnckaertFrancisco Avila CobosAnneleen DecockJill DeleuOlivier De WeverBert DhondtCeline EveraertHetty HelsmoortelAn HendrixEva HulstaertPieter MestdaghJustine NuytensAnnouck PhilippronKathleen SchoofsEveline Vanden EyndeJo VandesompeleRuben Van PaemelKimberly VerniersNurten Yigit

Exploration of the urinary proteome in the search for new biomarkers for prostate cancer : a promising role for extracellular vesicles

Bert DhondtGlenn VergauwenJan Van DeunEdward GeeurickxLien LippensJoeri TulkensPiet OstOlivier De WeverAn HendrixNicolaas Lumen

Immunologic impact of chemoradiation in cervical cancer and how immune cell infiltration could lead towards personalized treatment

Lien LippensMieke Van BockstalEmiel De JaegherePhilippe TummersAmin MakarSofie De GeyterKoen Van de VijverAn HendrixKatrien VandecasteeleHannelore Denys

Isolation and characterization of functionally active extracellular vesicles from culture medium conditioned by bovine embryos in vitro

Krishna PavaniAn HendrixWim Van Den BroeckLiesbeth CouckKatarzyna Joanna Szymańska-VandendriesscheJenne De KosterAnn Van SoomBart Leemans

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Performance assessment of total RNA sequencing of human biofluids and extracellular vesicles

Celine EveraertHetty HelsmoortelAnneleen DecockEva HulstaertRuben Van PaemelKimberly VerniersJustine NuytensJasper AnckaertNele NijsJoeri TulkensBert DhondtAn HendrixPieter MestdaghJo Vandesompele

A1 Journal Article in SCIENTIFIC REPORTS

Role of extracellular vesicles in bovine embryo communication

Krishna PavaniAnn Van SoomAn Hendrix

The generation and use of recombinant extracellular vesicles as biological reference material

Edward GeeurickxJoeri TulkensBert DhondtJan Van DeunLien LippensGlenn VergauwenDelphine De SutterKris GevaertFrancis ImpensPieter-Jan Van BockstalThomas De BeerGeert BraemsNico CallewaertPieter MestdaghJo VandesompeleHannelore DenysSven EyckermanOlivier De WeverAn Hendrix

A1 Journal Article in NATURE COMMUNICATIONS

Vesiclepedia 2019 : a compendium of RNA, proteins, lipids and metabolites in extracellular vesicles

Jan Van DeunAn Hendrix

A1 Journal Article in NUCLEIC ACIDS RESEARCH

2018

Bursting the bubble : introducing rigor in extracellular vesicle research to track and target cancer

Jan Van DeunOlivier De WeverAn Hendrix

Functionally active extracellular vesicles are released and taken up by zona-intact bovine embryos produced in vitro

Krishna PavaniAn HendrixBart LeemansAnn Van Soom

Minimal information for studies of extracellular vesicles 2018 (MISEV2018) : a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Olivier De WeverBert DhondtAn HendrixRochelle TixeiraJan Van Deun

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

Recombinant extracellular vesicles : biological reference material to standardize extracellular vesicle research

Edward GeeurickxJan Van DeunLien LippensJoeri TulkensBert DhondtGlenn VergauwenKris GevaertFrancis ImpensPieter-Jan Van BockstalThomas De BeerSven EyckermanPieter MestdaghJo VandesompeleGeert BraemsHannelore DenysOlivier De WeverAn Hendrix

Recombinant extracellular vesicles : biological reference material to standardize extracellular vesicle research

Edward GeeurickxJan Van DeunLien LippensJoeri TulkensBert DhondtGlenn VergauwenKris GevaertFrancis ImpensPieter-Jan Van BockstalThomas De BeerSven EyckermanPieter MestdaghJo VandesompeleGeert BraemsHannelore DenysMarc BrackeOlivier De WeverAn Hendrix

Repeatable, high-purity isolation of urinary extracellular vesicles for uro-oncological biomarker studies

Bert DhondtGlenn VergauwenJan Van DeunEdward GeeurickxJoeri TulkensLien LippensNicolaas LumenOlivier De WeverAn Hendrix

Reproduceerbare isolatie van hoog-zuivere urinaire extracellulaire vesikels voor uro-oncologische biomerkerstudies

Bert DhondtGlenn VergauwenJan Van DeunEdward GeeurickxJoeri TulkensLien LippensSarah BuelensElise De BleserFilip PoelaertTom ClaeysAn HendrixOlivier De WeverNicolaas Lumen

Reproducible high-purity isolation of urinary extracellular vesicles for uro-oncological biomarker studies

Bert DhondtGlenn VergauwenJan Van DeunEdward GeeurickxJoeri TulkensLien LippensSarah BuelensElise De BleserNicolaas LumenOlivier De WeverAn Hendrix

Reproducible isolation of high-purity urinary extracellular vesicles for uro-oncological biomarker studies

Bert DhondtGlenn VergauwenJan Van DeunEdward GeeurickxJoeri TulkensLien LippensSarah BuelensElise De BleserFilip PoelaertAn HendrixOlivier De WeverNicolaas Lumen

Summary of the ISEV workshop on extracellular vesicles as disease biomarkers, held in Birmingham, UK, during December 2017

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

The extracellular RNA quality control (exRNAQC) study : controlling pre-analytical variables of RNA sequencing in blood-based precision medicine

Francisco Avila CobosAnneleen DecockKatleen De PreterOlivier De WeverBram De WildeBert DhondtCeline EveraertHetty HelsmoortelAn HendrixEva HulstaertPieter MestdaghNele NijsAnnouck PhilippronJo VandesompeleRuben Van PaemelKimberly VerniersNurten Yigit

The small GTPase Rab27B stimulates secretion of a subpopulation of ARRDC1-positive small extracellular vesicles (SEV)

Lien LippensRobin BoiyBert DhondtBruno De GeestKatrien VandecasteeleHannelore DenysOlivier De WeverAn Hendrix

Transparent reporting of experimental parameters in assays measuring phenotypic steps in metastasis

Robin BoiyJonas SteenbruggeJan Van DeunAn HendrixEvelyne MeyerOlivier De Wever

A1 Journal Article in CLINICAL & EXPERIMENTAL METASTASIS

Urinary extracellular vesicle biomarkers in urological cancers : from discovery towards clinical implementation

Bert DhondtJan Van DeunNicolaas LumenOlivier De WeverAn Hendrix

A1 Journal Article in INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

2017

A novel community driven software for functional enrichment analysis of extracellular vesicles data

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

Circulating extracellular vesicles in cancer : a strategy to unlock hidden secrets

Glenn VergauwenRudy Van den BroeckeOlivier De WeverAn Hendrix

Confounding factors in extracellular vesicle ultrafiltration and protein analysis

Glenn VergauwenBert DhondtJan Van DeunEvy TimmermanKris GevaertGeert BraemsRudy Van den BroeckeVeronique CocquytHannelore DenysOlivier De WeverAn Hendrix

Confounding factors of ultrafiltration and protein analysis in extracellular vesicle research

Glenn VergauwenBert DhondtJan Van DeunEva De SmedtGeert BerxEvy TimmermanKris GevaertVeronique CocquytGeert BraemsRudy Van den BroeckeHannelore DenysOlivier De WeverAn Hendrix

A1 Journal Article in SCIENTIFIC REPORTS

EV-TRACK : transparent reporting and centralizing knowledge in extracellular vesicle research

Jan Van DeunPieter MestdaghEls BegheinLaurence BertierGeert BerxClara CasertBert DhondtEdward GeeurickxJan GettemansFarzaneh GhazaviHetty HelsmoortelCarina LeonelliLien LippensGloria MilaniLiselot MusQuentin RousseauBieke SoenAnneleen SteelsJoeri TulkensIsabel Van AudenhoveAlan Van GoethemNadine Van RoyNiels VandammeSuzanne VanhauwaertGlenn VergauwenAnnelynn WallaertOlivier De WeverJo VandesompeleAn Hendrix

A1 Journal Article in NATURE METHODS

Extracellular vesicles to diagnose and treat cancer

Joeri TulkensLien LippensGlenn VergauwenSarah JeurissenBert DhondtHannelore DenysAn Hendrix

A2 Journal Article in BELGIAN JOURNAL OF MEDICAL ONCOLOGY

Identification of confounding factors of EV isolation and protein analysis

Glenn VergauwenBert DhondtJan Van DeunEvy TimmermanKris GevaertVeronique CocquytGeert BraemsRudy Van den BroeckeHannelore DenysOlivier De WeverAn Hendrix

Is your article EV-TRACKed?

Jan Van DeunAn Hendrix

Editorial material

Methodological guidelines to study extracellular vesicles

An HendrixOlivier De Wever

A1 Journal Article in CIRCULATION RESEARCH

Purification of urinary extracellular vesicles for uro-oncological biomarker studies using an iodixanol (OptiprepTM) density gradient

Bert DhondtGlenn VergauwenJan Van DeunEdward GeeurickxTom ClaeysFilip PoelaertSarah BuelensNicolaas LumenAn HendrixOlivier De Wever

Purification of urinary extracellular vesicles for uro-oncological biomarker studies using an iodixanol (Optiprep™) density gradient

Bert DhondtGlenn VergauwenJan Van DeunEdward GeeurickxTom ClaeysFilip PoelaertSarah BuelensAn HendrixOlivier De WeverNicolaas Lumen

Secretome analysis of breast cancer-associated adipose tissue to identify paracrine regulators of breast cancer growth

Lore LapeireAn HendrixMieke Van BockstalJo VandesompeleGeert BraemsRudy Van den BroeckeMarc BrackeVeronique CocquytHannelore DenysOlivier De Wever

A1 Journal Article in ONCOTARGET

The extracellular RNA quality control (exRNAQC) study : testing and controlling pre-analytical variables of RNA sequencing on liquid biopsies

Anneleen DecockOlivier De WeverBert DhondtThibaut D'huyvetterHetty HelsmoortelAn HendrixAnnouck PhilippronKimberly VerniersPieter MestdaghJo Vandesompele

The isolation of morphologically intact and biologically active extracellular vesicles from the secretome of cancer-associated adipose tissue

Sarah JeurissenGlenn VergauwenJan Van DeunLore LapeireRudy Van den BroeckeGeert BraemsVeronique CocquytHannelore DenysAn Hendrix

A1 Journal Article in CELL ADHESION & MIGRATION

mRNA capture sequencing enabled liquid biopsy screening

Anneleen DecockOlivier De WeverBert DhondtAn HendrixHetty HelsmoortelPieter MestdaghPiet OstJo VandesompeleGlenn Vergauwen

2016

A new glucocerebrosidase-deficient neuronal cell model provides a tool to probe pathophysiology and therapeutics for Gaucher disease

A1 Journal Article in DISEASE MODELS & MECHANISMS

Comparing exosome-like vesicles with liposomes for the functional cellular delivery of small RNAs

Stephan StremerschRoosmarijn VandenbrouckeElien Van WonterghemAn HendrixStefaan De SmedtKoen Raemdonck

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

EV-TRAQ: tracking transparent reporting and quality to boost standardized extracellular vesicle research

Jan Van DeunPieter MestdaghJo VandesompeleOlivier De WeverAn Hendrix

Evidence-based clinical use of nanoscale extracellular vesicles in nanomedicine

Editorial material

Function of extracellular vesicle-associated miRNAs in metastasis

Bert DhondtQuentin RousseauOlivier De WeverAn Hendrix

A1 Journal Article in CELL AND TISSUE RESEARCH

Identification of a novel mechanism of blood-brain communication during peripheral inflammation via choroid plexus-derived extracellular vesicles

Sriram BalusuElien Van WonterghemRiet De RyckeKoen RaemdonckStephan StremerschKris GevaertMarjana BrkicDelphine DemeestereValerie VanhoorenAn HendrixClaude LibertRoosmarijn Vandenbroucke

A1 Journal Article in EMBO MOLECULAR MEDICINE

Identification of individual exosome-like vesicles by surface enhanced Raman spectroscopy

Stephan StremerschAn HendrixStefaan De SmedtAndre SkirtachKoen RaemdonckKevin Braeckmans

A1 Journal Article in SMALL

Isolation of extracellular vesicles from urine samples

Bert DhondtNicolaas LumenAn HendrixOlivier De Wever

Isolation of urinary extracellular vesicles for uro-oncological biomarker studies is complicated by Tamm-Horsfall protein

Bert DhondtGlenn VergauwenJan Van DeunEdward GeeurickxTom ClaeysFilip PoelaertAn HendrixOlivier De WeverNicolaas Lumen

Mapping the methodological diversity of EV isolation and characterization

Jan Van DeunPieter MestdaghJo VandesompeleOlivier De WeverAn Hendrix

The effects of quorum sensing peptides on colon cancer cells: implications for the role of the gut microbiome

Yorick JanssensEvelien WynendaeleFrederick VerbekeAn HendrixOlivier De WeverMarc BrackeBart De Spiegeleer

2015

Applying extracellular vesicles based therapeutics in clinical trials : an ISEV position paper

A2 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

Biological properties of extracellular vesicles and their physiological functions

An HendrixOlivier De Wever

A2 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

Communication of quorum sensing peptides with breast cancer cells

Frederick VerbekeEvelien WynendaeleMarianne LauwersAn HendrixChristian BurvenichOlivier De WeverMarc BrackeBart De Spiegeleer

Crosstalk between the microbiome and cancer cells by quorum sensing peptides

Evelien WynendaeleFrederick VerbekeMatthias D'HondtAn HendrixChristophe Van De WieleChristian BurvenichKathelijne PeremansOlivier De WeverMarc BrackeBart De Spiegeleer

A1 Journal Article in PEPTIDES

EVpedia: a community web portal for extracellular vesicles research

A1 Journal Article in BIOINFORMATICS

Exosomes released from breast cancer carcinomas stimulate cell movement

A1 Journal Article in PLOS ONE

Modulation of exosome release by cancer cells: a screening of potential inhibitors

An HendrixOlivier De Wever

The quorum sensing peptides PhrG, CSP and EDF promote angiogenesis and invasion of breast cancer cells in vitro

Bart De SpiegeleerFrederick VerbekeMatthias D'HondtAn HendrixChristophe Van De WieleChristian BurvenichKathelijne PeremansOlivier De WeverMarc BrackeEvelien Wynendaele

A1 Journal Article in PLOS ONE

2014

Bone marrow stromal cell-derived exosomes as communicators in drug resistance in multiple myeloma cells

An HendrixMiguel LemaireOlivier De Wever

A1 Journal Article in BLOOD

Cancer-associated adipose tissue promotes breast cancer progression by paracrine Oncostatin M and JAK3/STAT3 signaling

Lore LapeireAn HendrixKathleen LambeinMieke Van BockstalGeert BraemsRudy Van den BroeckePieter MestdaghJo VandesompeleChristian VanhoveVeronique CocquytMarc BrackeHannelore DenysOlivier De Wever

Cancer-associated adipose tissue promotes breast cancer progression by paracrine Oncostatin M and Jak/STAT3 signaling

Lore LapeireAn HendrixKathleen LambeinMieke Van BockstalGeert BraemsRudy Van den BroeckePieter MestdaghJo VandesompeleChristian VanhoveMarc BrackeVeronique CocquytHannelore DenysOlivier De Wever

A1 Journal Article in CANCER RESEARCH

Carcinoma-associated fibroblasts provide operational flexibility in metastasis

Olivier De WeverMieke Van BockstalMarcus MareelAn HendrixMarc Bracke

A1 Journal Article in SEMINARS IN CANCER BIOLOGY

Cellular disposal of miR23b by RAB27-dependent exosome release is linked to acquisition of metastatic properties

A1 Journal Article in CANCER RESEARCH

Crosstalk between mammalian cells and the microbiome through quorum sensing peptides, influencing cancer metastasis

Evelien WynendaeleFrederick VerbekeMatthias D'HondtAn HendrixChristophe Van De WieleChristian BurvenichKathelijne PeremansOlivier De WeverMarc BrackeBart De Spiegeleer

How does the human microbiome affect cancer outcome?

Evelien WynendaeleFrederick VerbekeMatthias D'HondtAn HendrixChristophe Van De WieleChristian BurvenichKathelijne PeremansOlivier De WeverMarc BrackeBart De Spiegeleer

On-chip light sheet illumination enables diagnostic size and concentration measurements of membrane vesicles in biofluids

Hendrik DeschoutKoen RaemdonckStephan StremerschAn HendrixMarc BrackeRudy Van den BroeckeJo DemeesterStefaan De SmedtFilip StrubbeKristiaan NeytsKevin Braeckmans

A1 Journal Article in NANOSCALE

Quorum sensing peptides: missing link between microbiome and health?

Evelien WynendaeleFrederick VerbekeMatthias D'HondtAn HendrixChristophe Van De WieleChristian BurvenichKathelijne PeremansOlivier De WeverMarc BrackeBart De Spiegeleer

Screening of inhibitors for modulation of exosome release by cancer cells

An HendrixOlivier De Wever

Single cell and spheroid collagen type I invasion assay

Olivier De WeverAn HendrixAstrid De BoeckGeert BraemsMarc Bracke

Bookchapter in Metastasis research protocols

The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling

Jan Van DeunPieter MestdaghLotte PyfferoenKarim VermaelenVeronique CocquytJo VandesompeleMarc BrackeOlivier De WeverAn Hendrix

The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling

Jan Van DeunPieter MestdaghVeronique CocquytKarim VermaelenJo VandesompeleMarc BrackeOlivier De WeverAn Hendrix

A2 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

2013

Bone marrow-derived mesenchymal stem cells promote colorectal cancer progression through paracrine neuregulin 1/HER3 signalling

Astrid De BoeckPatrick PauwelsAn HendrixHannelore DenysKathleen LambeinGeert BraemsMarc BrackeOlivier De Wever

A1 Journal Article in GUT

Differential secretome analysis of cancer-associated fibroblasts and bone marrow-derived precursors to identify microenvironmental regulators of colon cancer progression

Astrid De BoeckAn HendrixMieke Van BockstalPatrick PauwelsMarc BrackeOlivier De Wever

A1 Journal Article in PROTEOMICS

Electroporation-induced siRNA precipitation obscures the efficiency of siRNA loading into extracellular vesicles

Stephan StremerschKevin BraeckmansStefaan De SmedtAn HendrixKoen Raemdonck

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Protein secretome analysis of evolving and responding tumor ecosystems

Olivier De WeverAstrid De BoeckMarc BrackeAn Hendrix

A1 Journal Article in CURRENT PROTEOMICS

Rab27 GTPases distribute extracellular nanomaps for invasive growth and metastasis: implications for prognosis and treatment

An HendrixOlivier De Wever

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Rab27B-mediated metabolic reprogramming induces secretome acidification and chemoresistance in breast cancer cells

An HendrixMarc BrackeOlivier De Wever

A2 Journal Article in EXOSOMES AND MICROVESICLES

Vacuolar H+ ATPase expression and activity is required for Rab27B dependent invasive growth and metastasis of breast cancer

An HendrixKathleen LambeinHannelore DenysGwen SysGeert BraemsRudy Van den BroeckeVeronique CocquytMarc BrackeOlivier De Wever

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

2012

An immunohistochemical analysis of Rab27B distribution in fetal and adult tissue

An HendrixKathleen LambeinVeronique CocquytPatrick PauwelsMarc BrackeOlivier De Wever

A1 Journal Article in INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Identification of a GαGβγ, AKT and PKCα signalome associated with invasive growth in two genetic models of human breast cancer cell epithelial-to-mesenchyinal transition

Olivier De WeverAn HendrixKathleen LambeinMarc Bracke

A1 Journal Article in INTERNATIONAL JOURNAL OF ONCOLOGY

Rab27B, an ex(o)citing driver of breast cancer growth, invasion and metastasis

An HendrixMarc BrackeOlivier De Wever

Vesiclepedia : a compendium for extracellular vesicles with continuous community annotation

Editorial material

2011

Adipose tissue in breast cancer : not an idle bystander but an active participant in breast cancer progression

Lore LapeireAn HendrixKathleen LambeinGeert BraemsRudy Van den BroeckeMarc BrackeVeronique CocquytHannelore DenysOlivier De Wever

Exosome signaling in mammary gland development and cancer

A1 Journal Article in INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Experimental procedures to assay invasion-associated activities of primary cultured fibroblasts

An HendrixKoen JacobsAstrid De BoeckMarc BrackeOlivier De Wever

Bookchapter in Mouse as a model organism : from animal to cells

Rab27B, een biomarker voor ER-positieve borsttumoren met slechte prognose?

An HendrixMarc BrackeOlivier De Wever

A4 Journal Article in GUNAÏKEIA (NEDERLANDSE EDITIE)

Rab27B, een biomarker voor ER-positieve borsttumoren met slechte prognose?

An HendrixMarc BrackeOlivier De Wever

A2 Journal Article in ONCO (NEDERLANDSE ED.)

The secretory small GTPase Rab27B regulates invasive growth and metastasis in ER-positive breast cancer

A2 Journal Article in BELGIAN JOURNAL OF MEDICAL ONCOLOGY

The tumor ecosystem regulates the roads for invasion and metastasis

An HendrixMarc BrackeOlivier De Wever

A1 Journal Article in CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY

2010

An ex(o)citing machinery for invasive tumor growth

An HendrixMarc BrackeOlivier De Wever

A1 Journal Article in CANCER RESEARCH

Cellular and molecular mechanisms of cancer cell invasion

Olivier De WeverLore LapeireAstrid De BoeckAn Hendrix

A4 Journal Article in VERHANDELINGEN VAN DE KONINKLIJKE ACADEMIE VOOR GENEESKUNDE VAN BELGIË

Effect of the secretory small GTPase Rab27B on breast cancer growth, invasion, and metastasis

An HendrixPatrick PauwelsGeert BraemsHannelore DenysRudy Van den BroeckeJo LambertSimon Van BelleVeronique CocquytMarc BrackeOlivier De Wever

A1 Journal Article in JOURNAL OF THE NATIONAL CANCER INSTITUTE

Modeling and quantification of cancer cell invasion through collagen type I matrices

Olivier De WeverAn HendrixAstrid De BoeckGeert BraemsMarc Bracke

A1 Journal Article in INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

The secretory GTPase RAB27b drives poor prognosis in ER alpha-positive breast cancer

An HendrixHannelore DenysGeert BraemsPatrick PauwelsRudy Van den BroeckeVeronique CocquytMarc BrackeOlivier De Wever

The secretory small GTPase Rab27B as a marker for breast cancer progression

An HendrixGeert BraemsMarc BrackeOlivier De Wever

A1 Journal Article in ONCOTARGET

2009

The extracellular matrix regulates cancer progression and therapy response: implications for prognosis and treatment

Hannelore DenysGeert BraemsKathleen LambeinPatrick PauwelsAn HendrixAstrid De BoeckMarc BrackeOlivier De Wever

A1 Journal Article in CURRENT PHARMACEUTICAL DESIGN

The secretory small GTPase Rab27B regulates invasive tumor growth and metastasis through extracellular heat shock protein 90 alpha

An HendrixHannelore DenysRudy Van den BroeckeSimon Van BelleVeronique CocquytMarc BrackeOlivier De Wever

2008

Differential impact of TGF-β and EGF on fibroblast differentiation and invasion reciprocally promotes colon cancer cell invasion

Hannelore DenysLara DeryckeAn HendrixAlexander GheldofPatrick PauwelsMarc BrackeOlivier De Wever

A1 Journal Article in CANCER LETTERS

Netrin-1 induces apoptosis in human cervical tumor cells via the TAp73 alpha tumor suppressor

An HendrixOlivier De Wever

A1 Journal Article in Cancer Research

2007

Proinvasive activity of BMP-7 through SMAD4/src-independent and ERK/Rac JNK-dependent signaling pathways in colon cancer cells

Erik BruyneelAn HendrixOlivier De Wever

A1 Journal Article in CELLULAR SIGNALLING

Soluble cadherins as cancer biomarkers

Olivier De WeverLara DeryckeAn HendrixGert De MeerleerHerman DepypereMarc Bracke

A1 Journal Article in CLINICAL & EXPERIMENTAL METASTASIS

2006

Role of adipocyte-derived resistin in breast cancer

Dillis Van ValckenborghOlivier De WeverAn HendrixSimon Van BelleVeronique Cocquyt

2005

Commutators of PAR-1 signaling in cancer cell invasion reveal an essential role of the Rho-Rho kinase axis and tumor microenvironment

Olivier De WeverErik BruyneelAn HendrixMarcus MareelMarc Bracke

A1 Journal Article in ONCOGENE