Research Explorer

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Researcher

An Hendrix

151 Results

2023

A compendium of single extracellular vesicle flow cytometry

Joshua A. WelshGer J. A. ArkesteijnMichel BremerMichael CimorelliFrancoise Dignat-GeorgeBernd GiebelAndre GoergensAn HendrixMartine KuiperRomaric Lacroix et al.

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

Benchmarking blood collection tubes and processing intervals for extracellular vesicle performance metrics

Bert DhondtCláudio PinheiroEdward GeeurickxJoeri TulkensGlenn VergauwenEdwin Van Der PolRienk NieuwlandAnneleen DecockIlkka MiinalainenPekka Rappu et al.

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

Detection of breast cancer-specific extracellular vesicles with fiber-optic SPR biosensor

Yagmur YildizhanKaat DriessensHong Shen Kevin TsaoRobin BoiyDebby ThomasNick GeukensAn HendrixJeroen LammertynDragana Spasic

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Performance evaluation of RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study

Anneleen DecockOlivier De WeverCeline EveraertHetty HelsmoortelAn HendrixPieter MestdaghAnnelien MorlionJo VandesompeleRuben Van PaemelFrancisco Avila Cobos et al.

Rigor and standardization in extracellular vesicle research to enable clinical translation

Quentin RouxAn HendrixOlivier De Wever

2022

2022-RA-638-ESGO Pembrolizumab with multimodal immunomodulation in chemotherapy-pretreated cervical, endometrial, and uterine cancer : the PRIMMO phase II trial

Emiel De JaeghereSandra TuyaertsAnn M.T. van NuffelAnn BelmansKris BogaertsRegina Baiden-AmissahPeter VuylstekeStéphanie HenryXuan Bich TrinhPeter A. van Dam et al.

Assessing human embryo implantation competence through analysis of extracellular vesicles and their contents

Krishna PavaniKelly TillemanDominic StoopBart GadellaAn HendrixAnn Van Soom

Biomarkers in gynecological cancer : the potential of tumor infiltrating immune cells and circulating extracellular vesicles

Lien LippensHannelore DenysAn HendrixKatrien Vandecasteele

Hatching is modulated by microRNA-378a-3p derived from extracellular vesicles secreted by blastocysts

Krishna PavaniTim MeeseOsvaldo Américo Bogado PascottiniXueFeng GuanXiaoyuan LinLuc PeelmanJoachim HamacherFilip Van NieuwerburghDieter DeforceAnnekatrien Boel et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrins are enriched on aberrantly fucosylated tumour‐derived urinary extracellular vesicles

Md. Khirul IslamBert DhondtParvez SyedMisba KhanKamlesh GidwaniJason WebberAn HendrixGuido JensterTarja LamminenPeter J. Boström et al.

A2 Journal Article in JOURNAL OF EXTRACELLULAR BIOLOGY

Metastasized orthotopic patient-derived xenografts as preclinical model to guide therapeutic decision making in soft tissue sarcoma patients

Suzanne FischerElly De VlieghereDavid CreytensOlivier De WeverAn HendrixLore LapeireGwen Sys

Pembrolizumab, radiotherapy, and an immunomodulatory five-drug cocktail in pretreated patients with persistent, recurrent, or metastatic cervical or endometrial carcinoma : results of the phase II PRIMMO study

Emiel De JaeghereSandra TuyaertsAn M. T. Van NuffelAnn BelmansKris BogaertsRegina Baiden-AmissahLien LippensPeter VuylstekeStéphanie HenryXuan Bich Trinh et al.

A1 Journal Article in CANCER IMMUNOLOGY IMMUNOTHERAPY

Performance evaluation of RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study

Jasper AnckaertFrancisco Avila CobosAnneleen DecockPhilippe DecruyenaereJill DeleuKatleen De PreterOlivier De WeverJilke De WildeBert DhondtThibaut D'huyvetter et al.

Removal of platelets from blood plasma to improve the quality of extracellular vesicle research

Britta BettinAleksandra GaseckaBo LiBert DhondtAn HendrixRienk NieuwlandEdwin van der Pol

A1 Journal Article in JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Safety of pre- or postoperative accelerated radiotherapy in 5 fractions : a randomized pilot trial

Vincent VakaetHans VanhulleKoen Van de VijverIngeborg HildersonEline NaertWilfried De NeveJo Van DorpeAn HendrixMenekse GOKERHerman Depypere et al.

A1 Journal Article in BREAST

2021

Accelerated radiotherapy in 5 fractions in breast cancer patients : physician-assessed toxicity and patient-related outcomes

Hans Van HulleLiv VeldemanHannelore DenysAn Hendrix

Automated liquid handling for highly specific and reproducible density‐based separation of extracellular vesicles from human body fluids

Sofie Van DorpeLien LippensRobin BoiyHannelore DenysOlivier De WeverAn Hendrix

Circulating bacterial vesicles : from discovery towards clinical application

Joeri TulkensAn HendrixJo Vandesompele

Extracellular vesicles from follicular and ampullary fluid isolated by density gradient ultracentrifugation improve bovine embryo development and quality

Anise AsaadiNima AzaridolatabadHadi AtashiAnnelies RaesPetra Van DammeMichael HoelkerAn HendrixOsvaldo Américo Bogado PascottiniAnn Van SoomMojtaba Kafi et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

FO‐SPR biosensor calibrated with recombinant extracellular vesicles enables specific and sensitive detection directly in complex matrices

Yagmur YildizhanVenkata Suresh VajralaEdward GeeurickxCharles DeclerckNevena DuskunovicDelphine De SutterSam NoppenFilip DelportDominique ScholsJohannes V. Swinnen et al.

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

Importance of extracellular vesicle secretion at the blood-cerebrospinal fluid interface in the pathogenesis of Alzheimer’s disease

Charysse VandendriesscheSriram BalusuCaroline Van CauwenbergheMarjana BrkicMarie PauwelsNele PlehiersArnout BruggemanPieter DujardinGriet Van ImschootElien Van Wonterghem et al.

A1 Journal Article in ACTA NEUROPATHOLOGICA COMMUNICATIONS

MISpheroID : a knowledgebase and transparency tool for minimum information in spheroid identity

Arne PeirsmanEva BlondeelTasdiq AhmedJasper AnckaertDominique AudenaertTom BoterbergKrisztina BuzasNeil CarragherGastone CastellaniFlávia Castro et al.

A1 Journal Article in NATURE METHODS

Patient-derived cell lines and xenografts from sarcoma patients as models for therapeutic decision making

Suzanne FischerDavid CreytensGwen SysLore LapeireAn HendrixOlivier De Wever

Pembrolizumab, SBRT, and immunomodulation for recurrent and/or refractory cervical or endometrial carcinoma

Emiel De JaeghereSandra TuyaertsAnn M.T. Van NuffelLien LippensAn HendrixP. VuylstekeS. HenryX.B. TrinhP.A. Van DamS. Aspeslagh et al.

Recombinant extracellular vesicles as biological reference material for method development, data normalization and assessment of (pre-)analytical variables

Edward GeeurickxLien LippensPekka RappuBruno De GeestOlivier De WeverAn Hendrix

A1 Journal Article in NATURE PROTOCOLS

Robust sequential biophysical fractionation of blood plasma to study variations in the biomolecular landscape of systemically circulating extracellular vesicles across clinical conditions

Glenn VergauwenJoeri TulkensCláudio PinheiroFrancisco Avila CobosSandor DedeyneMarie-Angélique De ScheerderLinos VandekerckhoveFrancis ImpensIlkka MiinalainenGeert Braems et al.

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

Substantial performance differences among RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study

Anneleen DecockOlivier De WeverCeline EveraertHetty HelsmoortelAn HendrixPieter MestdaghAnnelien MorlionJo VandesompeleRuben Van PaemelFrancisco Avila Cobos et al.

Substantial performance differences among RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study

Anneleen DecockOlivier De WeverCeline EveraertHetty HelsmoortelAn HendrixPieter MestdaghAnnelien MorlionJo VandesompeleRuben Van PaemelFrancisco Avila Cobos et al.

The nature of blood(y) extracellular vesicles

Editorial material

2020

Analyzing bacterial extracellular vesicles in human body fluids by orthogonal biophysical separation and biochemical characterization

Joeri TulkensOlivier De WeverAn Hendrix

A1 Journal Article in NATURE PROTOCOLS

Development and application of a biological reference material for extracellular vesicle research

Edward GeeurickxOlivier De WeverAn HendrixSven Eycerman

Feasibility of mechanical extrusion to coat nanoparticles with extracellular vesicle membranes

Jan Van DeunQuentin RouxSarah DevilleThibaut Van AckerPekka RappuIlkka MiinalainenJyrki HeinoFrank VanhaeckeBruno De GeestOlivier De Wever et al.

A1 Journal Article in CELLS

Feasibility study on pre or postoperative accelerated radiotherapy (POP-ART) in breast cancer patients

Hans Van HulleVincent VakaetGiselle PostAnnick Van GrevelingChristel MontenAn HendrixKoen Van de VijverJo Van DorpePieter De VisschereGeert Braems et al.

A2 Journal Article in PILOT AND FEASIBILITY STUDIES

Immunologic impact of chemoradiation in cervical cancer and how immune cell infiltration could lead towards personalized treatment

Lien LippensMieke Van BockstalEmiel De JaegherePhilippe TummersAmin MakarSofie De GeyterKoen Van de VijverAn HendrixKatrien VandecasteeleHannelore Denys

A1 Journal Article in International Journal of Cancer

Increased levels of systemic LPS-positive bacterial extracellular vesicles in patients with intestinal barrier dysfunction

Joeri TulkensGlenn VergauwenJan Van DeunEdward GeeurickxBert DhondtLien LippensMarie-Angélique De ScheerderIlkka MiinalainenPekka RappuBruno De Geest et al.

A1 Journal Article in GUT

MIFlowCyt-EV : a framework for standardized reporting of extracellular vesicle flow cytometry experiments

Joshua A. WelshEdwin Van Der PolGer J.A. ArkesteijnMichel BremerAlain BrissonFrank CoumansFrançoise Dignat-GeorgeErika DugganIonita GhiranBernd Giebel et al.

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

Performance assessment of total RNA sequencing of human biofluids and extracellular vesicles

Celine EveraertHetty HelsmoortelAnneleen DecockEva HulstaertRuben Van PaemelKimberly VerniersJustine NuytensJasper AnckaertNele NijsJoeri Tulkens et al.

Preparation of multi-omics grade extracellular vesicles by density-based fractionation of urine

Bert DhondtNicolaas LumenOlivier De WeverAn Hendrix

A2 Journal Article in STAR PROTOCOLS

Substantial performance differences among RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control study-important considerations for liquid biopsies

Anneleen DecockJasper AnckaertCeline EveraertJustine NuytensScott KuerstenAn HendrixJo VandesompelePieter MestdaghBert DhondtRuben Van Paemel et al.

Targets, pitfalls and reference materials for liquid biopsy tests in cancer diagnostics

Edward GeeurickxAn Hendrix

A1 Journal Article in MOLECULAR ASPECTS OF MEDICINE

The EV-TRACK summary add-on: integration of experimental information in databases to ensure comprehensive interpretation of biological knowledge on extracellular vesicles

Quentin RouxJan Van DeunSandor DedeyneAn Hendrix

Editorial material

The separation and characterization of extracellular vesicles from medium conditioned by bovine embryos

Krishna PavaniXiaoyuan LinJoachim HamacherWim Van Den BroeckLiesbeth CouckLuc PeelmanAn HendrixAnn Van Soom

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Towards defining reference materials for measuring extracellular vesicle refractive index, epitope abundance, size and concentration

Joshua A. WelshEdwin PolBritta A. BettinDavid R. F. CarterAn HendrixMetka LenassiMarc‐André LangloisAlicia LlorenteArthur S. NesRienk Nieuwland et al.

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

Unravelling the proteomic landscape of extracellular vesicles in prostate cancer by density-based fractionation of urine

Bert DhondtEdward GeeurickxJoeri TulkensJan Van DeunGlenn VergauwenLien LippensIlkka MiinalainenPekka RappuJyrki HeinoPiet Ost et al.

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

2019

A supporting ecosystem to mature extracellular vesicles into clinical application

Olivier De WeverAn Hendrix

A1 Journal Article in EMBO JOURNAL

Considerations towards a roadmap for collection, handling and storage of blood extracellular vesicles

Aled ClaytonEric BoilardEdit, I BuzasLesley ChengJuan Manual Falcon-PerezChris GardinerDakota GustafsonAlice GualerziAn HendrixAndrew Hoffmann et al.

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

Dramatic differences in RNA purification kit performance in the extracellular RNA quality control study : important considerations for liquid biopsies

Annelien MorlionJasper AnckaertFrancisco Avila CobosAnneleen DecockOlivier De WeverBert DhondtCeline EveraertCarolina FierroHetty HelsmoortelAn Hendrix et al.

Dramatic differences in RNA purification kit performance in the extracellular RNA quality control study : important considerations for liquid biopsies

Annelien MorlionJasper AnckaertFrancisco Avila CobosAnneleen DecockOlivier De WeverBert DhondtCeline EveraertCarolina FierroHetty HelsmoortelAn Hendrix et al.

Establishment of 6 novel patient-derived sarcoma cell lines and 1 patient-derived carcinosarcoma cell line

Suzanne FischerDavid CreytensLore LapeireAn HendrixPiet PattynGwen Sys

Evaluating the impact of RNA purification kit and blood collection tube in the extracellular RNA quality control study : important considerations for liquid biopsies

Annelien MorlionJasper AnckaertFrancisco Avila CobosAnneleen DecockJill DeleuOlivier De WeverBert DhondtCeline EveraertCarolina FierroHetty Helsmoortel et al.

Exploration of the urinary proteome in the search for new biomarkers for prostate cancer : a promising role for extracellular vesicles

Bert DhondtGlenn VergauwenJan Van DeunEdward GeeurickxLien LippensJoeri Tulkenslkka MiinalainenPekka RappuJyrki Heino Oulu, FinlandPiet Ost et al.

Immunologic impact of chemoradiation in cervical cancer and how immune cell infiltration could lead towards personalized treatment

Lien LippensMieke Van BockstalEmiel De JaegherePhilippe TummersAmin MakarSofie De GeyterKoen Van de VijverAn HendrixKatrien VandecasteeleHannelore Denys

Isolation and characterization of functionally active extracellular vesicles from culture medium conditioned by bovine embryos in vitro

Krishna PavaniAn HendrixWim Van Den BroeckLiesbeth CouckKatarzyna Joanna Szymańska-VandendriesscheXiaoyuan LinJenne De KosterAnn Van SoomBart Leemans

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Performance assessment of total RNA sequencing of human biofluids and extracellular vesicles

Celine EveraertHetty HelsmoortelAnneleen DecockEva HulstaertRuben Van PaemelKimberly VerniersJustine NuytensJasper AnckaertNele NijsJoeri Tulkens et al.

A1 Journal Article in SCIENTIFIC REPORTS

Role of extracellular vesicles in bovine embryo communication

Krishna PavaniAnn Van SoomAn HendrixDawit Tesfaye

The generation and use of recombinant extracellular vesicles as biological reference material

Edward GeeurickxJoeri TulkensBert DhondtJan Van DeunLien LippensGlenn VergauwenElisa HeyrmanDelphine De SutterKris GevaertFrancis Impens et al.

A1 Journal Article in NATURE COMMUNICATIONS

Vesiclepedia 2019 : a compendium of RNA, proteins, lipids and metabolites in extracellular vesicles

Mohashin PathanPamali FonsekaSai V ChittiTaeyoung KangRahul SanwlaniJan Van DeunAn HendrixSuresh Mathivanan

A1 Journal Article in NUCLEIC ACIDS RESEARCH

2018

Bursting the bubble : introducing rigor in extracellular vesicle research to track and target cancer

Jan Van DeunOlivier De WeverAn Hendrix

Functionally active extracellular vesicles are released and taken up by zona-intact bovine embryos produced in vitro

Krishna PavaniAn HendrixBart LeemansAnn Van Soom

Minimal information for studies of extracellular vesicles 2018 (MISEV2018) : a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Clotilde ThéryKenneth W WitwerElena AikawaMaria Jose AlcarazJohnathon D AndersonRamaroson AndriantsitohainaAnna AntoniouTanina ArabFabienne ArcherGeorgia K Atkin-Smith et al.

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

Recombinant extracellular vesicles : biological reference material to standardize extracellular vesicle research

Edward GeeurickxElisa HeyrmanJan Van DeunLien LippensJoeri TulkensBert DhondtGlenn VergauwenKris GevaertFrancis ImpensIlkka Miinalainen et al.

Recombinant extracellular vesicles : biological reference material to standardize extracellular vesicle research

Edward GeeurickxElisa HeyrmanJan Van DeunLien LippensJoeri TulkensBert DhondtGlenn VergauwenKris GevaertFrancis ImpensIlkka Miinalainen et al.

Repeatable, high-purity isolation of urinary extracellular vesicles for uro-oncological biomarker studies

Bert DhondtGlenn VergauwenJan Van DeunEdward GeeurickxJoeri TulkensLien LippensIlkka MiinalainenPekka RappuJyrki HeinoNicolaas Lumen et al.

Reproduceerbare isolatie van hoog-zuivere urinaire extracellulaire vesikels voor uro-oncologische biomerkerstudies

Bert DhondtGlenn VergauwenJan Van DeunEdward GeeurickxJoeri TulkensLien LippensSarah BuelensElise De BleserFilip PoelaertTom Claeys et al.

Reproducible high-purity isolation of urinary extracellular vesicles for uro-oncological biomarker studies

Bert DhondtGlenn VergauwenJan Van DeunEdward GeeurickxJoeri TulkensLien LippensSarah BuelensElise De BleserIlkka MiinalainenPekka Rappu et al.

Reproducible isolation of high-purity urinary extracellular vesicles for uro-oncological biomarker studies

Bert DhondtGlenn VergauwenJan Van DeunEdward GeeurickxJoeri TulkensLien LippensSarah BuelensElise De BleserFilip PoelaertTom Claeys et al.

Summary of the ISEV workshop on extracellular vesicles as disease biomarkers, held in Birmingham, UK, during December 2017

Aled ClaytonDominik BuschmannJ. Brian ByrdDavid R. F. CarterLesley ChengCarolyn ComptonGeorge DaaboulAndrew DevittJuan Manuel Falcon-PerezChris Gardiner et al.

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

The extracellular RNA quality control (exRNAQC) study : controlling pre-analytical variables of RNA sequencing in blood-based precision medicine

Francisco Avila CobosAnneleen DecockKatleen De PreterOlivier De WeverBram De WildeBert DhondtCeline EveraertCarolina FierroHetty HelsmoortelAn Hendrix et al.

The extracellular RNA quality control (exRNAQC) study : controlling pre-analytical variables of RNA sequencing in blood-based precision medicine

Francisco Avila CobosAnneleen DecockKatleen De PreterBert DhondtOlivier De WeverBram De WildeCeline EveraertCarolina FierroHetty HelsmoortelAn Hendrix et al.

The small GTPase Rab27B stimulates secretion of a subpopulation of ARRDC1-positive small extracellular vesicles (SEV)

Lien LippensRobin BoiyBert DhondtBruno De GeestKatrien VandecasteeleHannelore DenysOlivier De WeverAn Hendrix

Transparent reporting of experimental parameters in assays measuring phenotypic steps in metastasis

Robin BoiyJonas SteenbruggeJan Van DeunAn HendrixEvelyne MeyerOlivier De Wever

A1 Journal Article in CLINICAL & EXPERIMENTAL METASTASIS

Urinary extracellular vesicle biomarkers in urological cancers : from discovery towards clinical implementation

Bert DhondtJan Van DeunSilke VermaerkeArio de MarcoNicolaas LumenOlivier De WeverAn Hendrix

A1 Journal Article in INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

2017

A novel community driven software for functional enrichment analysis of extracellular vesicles data

Mohashin PathanShivakumar KeerthikumarDavid ChisangaRiccardo AlessandroChing-Seng AngPhilip AskenaseArsen O BatagovAlberto Benito-MartinGiovanni CamussiAled Clayton et al.

A1 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

Circulating extracellular vesicles in cancer : a strategy to unlock hidden secrets

Glenn VergauwenRudy Van den BroeckeOlivier De WeverAn Hendrix

Confounding factors in extracellular vesicle ultrafiltration and protein analysis

Glenn VergauwenBert DhondtJan Van DeunEvy TimmermanKris GevaertGeert BraemsRudy Van den BroeckeVeronique CocquytHannelore DenysOlivier De Wever et al.

Confounding factors of ultrafiltration and protein analysis in extracellular vesicle research

Glenn VergauwenBert DhondtJan Van DeunEva De SmedtGeert BerxEvy TimmermanKris GevaertIlkka MiinalainenVeronique CocquytGeert Braems et al.

A1 Journal Article in SCIENTIFIC REPORTS

EV-TRACK : transparent reporting and centralizing knowledge in extracellular vesicle research

Jan Van DeunPieter MestdaghPatrizia AgostinisÖzden AkaySushma AnandJasper AnckaertZoraida Andreu MartinezTine BaetensEls BegheinLaurence Bertier et al.

A1 Journal Article in NATURE METHODS

Extracellular vesicles to diagnose and treat cancer

Joeri TulkensLien LippensGlenn VergauwenSarah JeurissenBert DhondtHannelore DenysAn Hendrix

A2 Journal Article in BELGIAN JOURNAL OF MEDICAL ONCOLOGY

Identification of confounding factors of EV isolation and protein analysis

Glenn VergauwenBert DhondtJan Van DeunEvy TimmermanKris GevaertVeronique CocquytGeert BraemsRudy Van den BroeckeHannelore DenysOlivier De Wever et al.

Is your article EV-TRACKed?

Jan Van DeunAn Hendrix

Editorial material

Methodological guidelines to study extracellular vesicles

Frank AW CoumansAlain R BrissonEdit I BuzasFrançoise Dignat-GeorgeEsther EE DreesSamir El-AndaloussiCostanza EmanueliAleksandra GaseckaAn HendrixAndrew F Hill et al.

A1 Journal Article in CIRCULATION RESEARCH

Purification of urinary extracellular vesicles for uro-oncological biomarker studies using an iodixanol (OptiprepTM) density gradient

Bert DhondtGlenn VergauwenJan Van DeunEdward GeeurickxTom ClaeysFilip PoelaertSarah BuelensNicolaas LumenAn HendrixOlivier De Wever

Purification of urinary extracellular vesicles for uro-oncological biomarker studies using an iodixanol (Optiprep™) density gradient

Bert DhondtGlenn VergauwenJan Van DeunEdward GeeurickxTom ClaeysFilip PoelaertSarah BuelensAn HendrixOlivier De WeverNicolaas Lumen

Secretome analysis of breast cancer-associated adipose tissue to identify paracrine regulators of breast cancer growth

Lore LapeireAn HendrixEvelyne LecoutereMieke Van BockstalJo VandesompeleDawn MaynardGeert BraemsRudy Van den BroeckeCathérine MüllerMarc Bracke et al.

A1 Journal Article in ONCOTARGET

The extracellular RNA quality control (exRNAQC) study : testing and controlling pre-analytical variables of RNA sequencing on liquid biopsies

Anneleen DecockOlivier De WeverBert DhondtThibaut D'huyvetterHetty HelsmoortelAn HendrixAnnouck PhilippronKimberly VerniersPieter MestdaghJo Vandesompele

The isolation of morphologically intact and biologically active extracellular vesicles from the secretome of cancer-associated adipose tissue

Sarah JeurissenGlenn VergauwenJan Van DeunLore LapeireVictoria DepoorterIlkka MiinalainenRaija SormunenRudy Van den BroeckeGeert BraemsVeronique Cocquyt et al.

A1 Journal Article in CELL ADHESION & MIGRATION

mRNA capture sequencing enabled liquid biopsy screening

Anneleen DecockOlivier De WeverBert DhondtCarolina FierroAn HendrixHetty HelsmoortelScott KuerstenPieter MestdaghNele NijsPiet Ost et al.

2016

A new glucocerebrosidase-deficient neuronal cell model provides a tool to probe pathophysiology and therapeutics for Gaucher disease

Wendy WestbroekMatthew NguyenMarina SiebertTaylor LindstromRobert A BurnettElma AflakiOlive JungRafael TamargoJorge L Rodriguez-GilWalter Acosta et al.

A1 Journal Article in DISEASE MODELS & MECHANISMS

Comparing exosome-like vesicles with liposomes for the functional cellular delivery of small RNAs

Stephan StremerschRoosmarijn VandenbrouckeElien Van WonterghemAn HendrixStefaan De SmedtKoen Raemdonck

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

EV-TRAQ: tracking transparent reporting and quality to boost standardized extracellular vesicle research

Jan Van DeunPieter MestdaghJasper AnckaertJo VandesompeleOlivier De WeverAn Hendrix

Evidence-based clinical use of nanoscale extracellular vesicles in nanomedicine

Stefano FaisLorraine O'DriscollFrancesc E BorrasEdit BuzasGiovanni CamussiFrancesco CappelloJoana CarvalhoAnabela Cordeiro da SilvaHernando Del PortilloSamir El Andaloussi et al.

Editorial material

Function of extracellular vesicle-associated miRNAs in metastasis

Bert DhondtQuentin RousseauOlivier De WeverAn Hendrix

A1 Journal Article in CELL AND TISSUE RESEARCH

Identification of a novel mechanism of blood-brain communication during peripheral inflammation via choroid plexus-derived extracellular vesicles

Sriram BalusuElien Van WonterghemRiet De RyckeKoen RaemdonckStephan StremerschKris GevaertMarjana BrkicDelphine DemeestereValerie VanhoorenAn Hendrix et al.

A1 Journal Article in EMBO MOLECULAR MEDICINE

Identification of individual exosome-like vesicles by surface enhanced Raman spectroscopy

Stephan StremerschMonica MarroBat-El PinchasikPieter BaatsenAn HendrixStefaan De SmedtPablo Loza-AlvarezAndre SkirtachKoen RaemdonckKevin Braeckmans

A1 Journal Article in SMALL

Isolation of extracellular vesicles from urine samples

Bert DhondtNicolaas LumenAn HendrixOlivier De Wever

Isolation of urinary extracellular vesicles for uro-oncological biomarker studies is complicated by Tamm-Horsfall protein

Bert DhondtDelphine DavelooseGlenn VergauwenJan Van DeunEdward GeeurickxTom ClaeysFilip PoelaertAn HendrixOlivier De WeverNicolaas Lumen

Mapping the methodological diversity of EV isolation and characterization

Jan Van DeunPieter MestdaghJo VandesompeleOlivier De WeverAn Hendrix

The effects of quorum sensing peptides on colon cancer cells: implications for the role of the gut microbiome

Yorick JanssensEvelien WynendaeleFrederick VerbekeAn HendrixOlivier De WeverMarc BrackeBart De Spiegeleer

2015

Applying extracellular vesicles based therapeutics in clinical trials : an ISEV position paper

Thomas LenerMario GimonaLudwig AignerVerena BörgerEdit BuzasGiovanni CamussiNathalie ChaputDevasis ChatterjeeFelipe A CourtHernando A del Portillo et al.

A2 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

Biological properties of extracellular vesicles and their physiological functions

María Yáñez-MóPia R-M SiljanderZoraida AndreuApolonija Bedina ZavecFrancesc E BorràsEdit I BuzasKrisztina BuzasEnriqueta CasalFrancesco CappelloJoana Carvalho et al.

A2 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

Communication of quorum sensing peptides with breast cancer cells

Frederick VerbekeEvelien WynendaeleMarianne LauwersAn HendrixChristian BurvenichOlivier De WeverMarc BrackeBart De Spiegeleer

Crosstalk between the microbiome and cancer cells by quorum sensing peptides

Evelien WynendaeleFrederick VerbekeMatthias D'HondtAn HendrixChristophe Van De WieleChristian BurvenichKathelijne PeremansOlivier De WeverMarc BrackeBart De Spiegeleer

A1 Journal Article in PEPTIDES

EVpedia: a community web portal for extracellular vesicles research

Dae-Kyum KimJaewook LeeSae Rom KimDong-Sic ChoiYae Jin YoonJi Hyun KimGyeongyun GoDinh NhungKahye HongSu Chul Jang et al.

A1 Journal Article in BIOINFORMATICS

Exosomes released from breast cancer carcinomas stimulate cell movement

Dinari A HarrisSajni H PatelMarjan GucekAn HendrixWendy WestbroekJustin W Taraska

A1 Journal Article in PLOS ONE

Modulation of exosome release by cancer cells: a screening of potential inhibitors

Gertjan RasschaertAn HendrixOlivier De Wever

The quorum sensing peptides PhrG, CSP and EDF promote angiogenesis and invasion of breast cancer cells in vitro

Bart De SpiegeleerFrederick VerbekeMatthias D'HondtAn HendrixChristophe Van De WieleChristian BurvenichKathelijne PeremansOlivier De WeverMarc BrackeEvelien Wynendaele

A1 Journal Article in PLOS ONE

2014

Bone marrow stromal cell-derived exosomes as communicators in drug resistance in multiple myeloma cells

Jinheng WangAn HendrixSophie HernotMiguel LemaireELKE DE BRUYNEEls Van ValckenborghTony LahoutteOlivier De WeverKarin VanderkerkenEline Menu

A1 Journal Article in BLOOD

Cancer-associated adipose tissue promotes breast cancer progression by paracrine Oncostatin M and JAK3/STAT3 signaling

Lore LapeireAn HendrixKathleen LambeinMieke Van BockstalGeert BraemsRudy Van den BroeckeRidha LimamePieter MestdaghJo VandesompeleChristian Vanhove et al.

Cancer-associated adipose tissue promotes breast cancer progression by paracrine Oncostatin M and Jak/STAT3 signaling

Lore LapeireAn HendrixKathleen LambeinMieke Van BockstalGeert BraemsRudy Van den BroeckeRIDHA LIMAMEPieter MestdaghJo VandesompeleChristian Vanhove et al.

A1 Journal Article in CANCER RESEARCH

Carcinoma-associated fibroblasts provide operational flexibility in metastasis

Olivier De WeverMieke Van BockstalMarcus MareelAn HendrixMarc Bracke

A1 Journal Article in SEMINARS IN CANCER BIOLOGY

Cellular disposal of miR23b by RAB27-dependent exosome release is linked to acquisition of metastatic properties

Marie Stampe OstenfeldDennis K JeppesenJens R LaurbergAnders T BoysenJesper B BramsenBjarke Primdal-BengtsonAn HendrixPhilippe LamyFrederik Dagnaes-HansenMads H Rasmussen et al.

A1 Journal Article in CANCER RESEARCH

Crosstalk between mammalian cells and the microbiome through quorum sensing peptides, influencing cancer metastasis

Evelien WynendaeleFrederick VerbekeMatthias D'HondtAn HendrixChristophe Van De WieleChristian BurvenichKathelijne PeremansOlivier De WeverMarc BrackeBart De Spiegeleer

How does the human microbiome affect cancer outcome?

Evelien WynendaeleFrederick VerbekeMatthias D'HondtAn HendrixChristophe Van De WieleChristian BurvenichKathelijne PeremansOlivier De WeverMarc BrackeBart De Spiegeleer

On-chip light sheet illumination enables diagnostic size and concentration measurements of membrane vesicles in biofluids

Hendrik DeschoutKoen RaemdonckStephan StremerschPietro MaoddiGuillaume MernierPhilippe RenaudSebastien JiguetAn HendrixMarc BrackeRudy Van den Broecke et al.

A1 Journal Article in NANOSCALE

Quorum sensing peptides: missing link between microbiome and health?

Evelien WynendaeleFrederick VerbekeMatthias D'HondtAn HendrixChristophe Van De WieleChristian BurvenichKathelijne PeremansOlivier De WeverMarc BrackeBart De Spiegeleer

Screening of inhibitors for modulation of exosome release by cancer cells

Gertjan RasschaertAn HendrixOlivier De Wever

Single cell and spheroid collagen type I invasion assay

Olivier De WeverAn HendrixAstrid De BoeckFrank EertmansWendy WestbroekGeert BraemsMarc Bracke

Bookchapter in Metastasis research protocols

The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling

Jan Van DeunPieter MestdaghRaija SormunenLotte PyfferoenKarim VermaelenVeronique CocquytJo VandesompeleMarc BrackeOlivier De WeverAn Hendrix

The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling

Jan Van DeunPieter MestdaghRaija SormunenVeronique CocquytKarim VermaelenJo VandesompeleMarc BrackeOlivier De WeverAn Hendrix

A2 Journal Article in JOURNAL OF EXTRACELLULAR VESICLES

2013

Bone marrow-derived mesenchymal stem cells promote colorectal cancer progression through paracrine neuregulin 1/HER3 signalling

Astrid De BoeckPatrick PauwelsKaren HensenJean-Luc RummensWendy WestbroekAn HendrixDawn MaynardHannelore DenysKathleen LambeinGeert Braems et al.

A1 Journal Article in GUT

Differential secretome analysis of cancer-associated fibroblasts and bone marrow-derived precursors to identify microenvironmental regulators of colon cancer progression

Astrid De BoeckAn HendrixDawn MaynardMieke Van BockstalAnnick DaniëlsPatrick PauwelsChristian GespachMarc BrackeOlivier De Wever

A1 Journal Article in PROTEOMICS

Electroporation-induced siRNA precipitation obscures the efficiency of siRNA loading into extracellular vesicles

Sander AA KooijmansStephan StremerschKevin BraeckmansStefaan De SmedtAn HendrixMatthew JA WoodRaymond M SchiffelersKoen RaemdonckPieter Vader

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Protein secretome analysis of evolving and responding tumor ecosystems

Olivier De WeverAstrid De BoeckDawn MaynardMarc BrackeAn Hendrix

A1 Journal Article in CURRENT PROTEOMICS

Rab27 GTPases distribute extracellular nanomaps for invasive growth and metastasis: implications for prognosis and treatment

An HendrixOlivier De Wever

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Rab27B-mediated metabolic reprogramming induces secretome acidification and chemoresistance in breast cancer cells

An HendrixCarla CicconeChristian GespachMarc BrackeOlivier De WeverWendy Westbroek

A2 Journal Article in EXOSOMES AND MICROVESICLES

Vacuolar H+ ATPase expression and activity is required for Rab27B dependent invasive growth and metastasis of breast cancer

An HendrixRaija SormunenWendy WestbroekKathleen LambeinHannelore DenysGwen SysGeert BraemsRudy Van den BroeckeVeronique CocquytChristian Gespach et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

2012

An immunohistochemical analysis of Rab27B distribution in fetal and adult tissue

An HendrixKathleen LambeinWendy WestbroeckMiguel C SeabraVeronique CocquytPatrick PauwelsMarc BrackeChristian GespachOlivier De Wever

A1 Journal Article in INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Identification of a GαGβγ, AKT and PKCα signalome associated with invasive growth in two genetic models of human breast cancer cell epithelial-to-mesenchyinal transition

Radia Ouelaa-BenslamaOlivier De WeverAn HendrixMichèle SabbahKathleen LambeinDavid LandGrégoire PrévostMarc BrackeMien-Chie HungAnnette K Larsen et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF ONCOLOGY

Rab27B, an ex(o)citing driver of breast cancer growth, invasion and metastasis

An HendrixWendy WestbroekMarc BrackeOlivier De Wever

Vesiclepedia : a compendium for extracellular vesicles with continuous community annotation

Hina KalraRichard J SimpsonHong JiElena AikawaPeter AltevogtPhilip AskenaseVincent C BondFrancesc E BorràsXandra BreakefieldVivian Budnik et al.

Editorial material

2011

Adipose tissue in breast cancer : not an idle bystander but an active participant in breast cancer progression

Lore LapeireAn HendrixKathleen LambeinGeert BraemsP ValetRudy Van den BroeckeMarc BrackeVeronique CocquytHannelore DenysOlivier De Wever

Exosome signaling in mammary gland development and cancer

An HendrixAlistair Hume

A1 Journal Article in INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Experimental procedures to assay invasion-associated activities of primary cultured fibroblasts

An HendrixKoen JacobsAstrid De BoeckWendy WestbroeckMarc BrackeOlivier De Wever

Bookchapter in Mouse as a model organism : from animal to cells

Rab27B, een biomarker voor ER-positieve borsttumoren met slechte prognose?

An HendrixMarc BrackeOlivier De Wever

A2 Journal Article in ONCO (NEDERLANDSE ED.)

Rab27B, een biomarker voor ER-positieve borsttumoren met slechte prognose?

An HendrixMarc BrackeOlivier De Wever

A4 Journal Article in GUNAÏKEIA (NEDERLANDSE EDITIE)

The secretory small GTPase Rab27B regulates invasive growth and metastasis in ER-positive breast cancer

A2 Journal Article in BELGIAN JOURNAL OF MEDICAL ONCOLOGY

The tumor ecosystem regulates the roads for invasion and metastasis

An HendrixChristian GespachMarc BrackeOlivier De Wever

A1 Journal Article in CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY

2010

An ex(o)citing machinery for invasive tumor growth

An HendrixWendy WestbroekMarc BrackeOlivier De Wever

A1 Journal Article in CANCER RESEARCH

Cellular and molecular mechanisms of cancer cell invasion

Olivier De WeverLore LapeireAstrid De BoeckAn Hendrix

A4 Journal Article in VERHANDELINGEN VAN DE KONINKLIJKE ACADEMIE VOOR GENEESKUNDE VAN BELGIË

Effect of the secretory small GTPase Rab27B on breast cancer growth, invasion, and metastasis

An HendrixDawn MaynardPatrick PauwelsGeert BraemsHannelore DenysRudy Van den BroeckeJo LambertSimon Van BelleVeronique CocquytChristian Gespach et al.

A1 Journal Article in JOURNAL OF THE NATIONAL CANCER INSTITUTE

Modeling and quantification of cancer cell invasion through collagen type I matrices

Olivier De WeverAn HendrixAstrid De BoeckWendy WestbroekGeert BraemsShahin EmamiMichèle SabbahChristian GespachMarc Bracke

A1 Journal Article in INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

The secretory GTPase RAB27b drives poor prognosis in ER alpha-positive breast cancer

An HendrixHannelore DenysGeert BraemsPatrick PauwelsRudy Van den BroeckeVeronique CocquytWendy WestbroekMarc BrackeOlivier De Wever

The secretory small GTPase Rab27B as a marker for breast cancer progression

An HendrixGeert BraemsMarc BrackeMiguel C SeabraWilliam A GahlOlivier De WeverWendy Westbroek

A1 Journal Article in ONCOTARGET

2009

The extracellular matrix regulates cancer progression and therapy response: implications for prognosis and treatment

Hannelore DenysGeert BraemsKathleen LambeinPatrick PauwelsAn HendrixAstrid De BoeckVeronique MathieuMarc BrackeOlivier De Wever

A1 Journal Article in CURRENT PHARMACEUTICAL DESIGN

The secretory small GTPase Rab27B regulates invasive tumor growth and metastasis through extracellular heat shock protein 90 alpha

An HendrixD MaynardP PauwelsG BraemsHannelore DenysRudy Van den BroeckeSimon Van BelleVeronique CocquytMarc BrackeM Seabra et al.

2008

Differential impact of TGF-β and EGF on fibroblast differentiation and invasion reciprocally promotes colon cancer cell invasion

Hannelore DenysLara DeryckeAn HendrixWendy WestbroekAlexander GheldofKishan NarinePatrick PauwelsChristian GespachMarc BrackeOlivier De Wever

A1 Journal Article in CANCER LETTERS

Netrin-1 induces apoptosis in human cervical tumor cells via the TAp73 alpha tumor suppressor

Jean-Pierre RoperchKarima El QuadraniAn HendrixShabin EmamiOlivier De WeverGerry MelinaChristian Gespach

A1 Journal Article in Cancer Research

2007

Proinvasive activity of BMP-7 through SMAD4/src-independent and ERK/Rac JNK-dependent signaling pathways in colon cancer cells

C GRIJELMOC RODRIGUEM SVRCEKErik BruyneelAn HendrixOlivier De WeverC GESPACH

A1 Journal Article in CELLULAR SIGNALLING

Soluble cadherins as cancer biomarkers

Olivier De WeverLara DeryckeAn HendrixGert De MeerleerF GODEAUHerman DepypereMarc Bracke

A1 Journal Article in CLINICAL & EXPERIMENTAL METASTASIS

2006

Role of adipocyte-derived resistin in breast cancer

Dillis Van ValckenborghOlivier De WeverAn HendrixM BRACKER VANDENBROECKESimon Van BelleP PAUWELSVeronique CocquytHANNELORE DENYS

2005

Commutators of PAR-1 signaling in cancer cell invasion reveal an essential role of the Rho-Rho kinase axis and tumor microenvironment

QD NGUYENOlivier De WeverErik BruyneelAn HendrixWZ XIEA LOMBETM LEIBLMarcus MareelF GIESELERMarc Bracke et al.

A1 Journal Article in ONCOGENE