Project

Mitophagy and the control of lifespan in Caenorhabditis elegans

Code
3F003111
Duration
01 October 2011 → 30 September 2015
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Animal biology
    • Biochemistry and metabolism
    • General biology
  • Medical and health sciences
    • Gerontology and geriatrics
    • Medical biochemistry and metabolism
    • Gerontology and geriatrics
    • Medical biochemistry and metabolism
    • Nursing
    • Gerontology and geriatrics
    • Medical biochemistry and metabolism
  • Agricultural and food sciences
    • Veterinary medicine
Keywords
caenorhabditis elegans mitochondria aging autophagy
 
Project description

Because of their role in energy metabolism and redox balance, mitochondria are probably of crucial importance to the aging process. By use of a mitchondrially targeted photoswitchable protein, we study the mitochondrial autophagy and renewal in aging worms as well as in mutants with extended lifespan.