Project

The role of myosin II in cancer invastion

Duration
01 January 2007 → 31 December 2009
Funding
Research Foundation - Flanders (FWO)
Promotor
Research disciplines
  • Medical and health sciences
    • Morphological sciences
    • Oncology
    • Morphological sciences
    • Oncology
    • Morphological sciences
    • Oncology
Keywords
cadherin invasion myosin
 
Project description

Myosin II was detected in invasive breast cancer cellines but not in not-invasive ones. The causal relationship between pyosin II and invasion is investigated and the actionmechanism, which presumably implicaties cadherins and integrins, is studied. Furthermore the effect of anti-invasive agents on myosin II, and the expression of the molecule in surgically removed breast cancer specimens fall within the project.