Research Explorer

Project

Unraveling the universal principles underlying duplication resistance in plant and animal genomes.
Code
3E004813
Duration
01 October 2013 → 01 May 2017
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Scientific computing
    • Bioinformatics and computational biology
  • Medical and health sciences
    • Bioinformatics and computational biology
    • Bioinformatics and computational biology
    • Public health care
    • Public health services
    • Bioinformatics and computational biology
  • Engineering and technology
    • Scientific computing
Keywords
gene duplication Single-copy genes evolution
 
Project description
 

We aim to study the properties and constraints acting on duplication resistant genes, i.e. genes that are under selection to be maintained as a single copy in the genome. In particular we will investigate the hypothesis that duplication-resistant genes constitute a fragile network core, that has been evolutionary conserved and needs to remain undisrupted at all times.