Code
01CD10023
Looptijd
01-11-2023 → 30-04-2024
Financiering
Regional and community funding: Special Research Fund
Promotor
Onderzoeksdisciplines
-
Medical and health sciences
- Analysis of next-generation sequence data
- Computational transcriptomics and epigenomics
- Molecular biophysics
Trefwoorden
cel vrij DNA
vloeibare biopten
Cel vrij RNA
androgeen receptor
geavanceerde kanker
biomarker
Projectomschrijving
Advanced tumours relapse and show different resistance mechanisms. Because tissue biopsies are discomforting for patients our focus is on liquid biopsies (plasma). We will detect alterations in circulating DNA as prognostic biomarkers in the context of radiotherapie +/- immunotherapie. Circulating RNA will be investigated in the context of resistance to hormonal therapy in advanced prostate cancer.