Research Explorer

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Project

Cellular and molecular mechanisms mediating the adverse respiratory effects of particulate air pollution: focus on the epithelium

Outputs and Outcomes

Code

3E011912

Duration

01 October 2012 → 31 October 2019

Funding

Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)

Promotor

Guy Joos

Fellow

Sharen Provoost

Research disciplines

Medical and health sciences
- Immunology
- Respiratory medicine
- Immunology
- Respiratory medicine
- Immunology
- Respiratory medicine

Keywords

diesel exhaust particulate matter dendritic cells epithelium

Project description

We will examine the mechanisms how particulate matter inhalation promote allergic sensitization. More specifically, we will study how diesel exhaust particles affect the communication between airway epithelium and lung dendritic cells, since these cells are critical in inducing allergic inflammatory responses in the lung.

English

Dutch

English

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