Project

Cellular and molecular mechanisms mediating the adverse respiratory effects of particulate air pollution: focus on the epithelium

Duration
01 October 2012 → 31 October 2019
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Research disciplines
  • Medical and health sciences
    • Immunology
    • Respiratory medicine
    • Immunology
    • Respiratory medicine
    • Immunology
    • Respiratory medicine
Keywords
diesel exhaust particulate matter dendritic cells epithelium
 
Project description

We will examine the mechanisms how particulate matter inhalation promote allergic sensitization. More specifically, we will study how diesel exhaust particles affect the communication between airway epithelium and lung dendritic cells, since these cells are critical in inducing allergic inflammatory responses in the lung.