Research Explorer

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Project

A novel player in intestinal inflammation and motility

Outputs and Outcomes

Publications

CARD14 signalosome formation is associated with its endosomal relocation and mTORC1-induced keratinocyte proliferation

Paul A O'SullivanAigerim AidarovaInna AfoninaJoan ManilsTeresa L M ThurstonRachel InstrellMichael HowellStefan BoeingSashini RanawanaMelanie HerpelsRiwia ChetienMatilda BassaHelen R FlynnDavid FrithAmbrosius SnijdersAshleigh HowesRudi BeyaertAnne BowcockSteve C Ley et al.

A1 Journal Article in BIOCHEMICAL JOURNAL

Polo-like kinase 1 (PLK1) is a novel CARD14-binding protein in keratinocytes

Stella IliakiMarja KreikeNatalia Ferreras MorenoFemke De MeyerAigerim AidarovaHarald BraunClaude LibertInna AfoninaRudi Beyaert

A1 Journal Article in BIOCHEMICAL PHARMACOLOGY

Chimeric and mutant CARD9 constructs enable analyses of conserved and diverged autoinhibition mechanisms in the CARD-CC protein family

Jens StaalYasmine DriegeFemke Van GaeverJill SteelsRudi Beyaert

A1 Journal Article in FEBS JOURNAL

Proteolytic activity of the paracaspase MALT1 is involved in epithelial restitution and mucosal healing

Leonie WittnerLukas WagenerJakob J. WieseIris StolzerSusanne M. KrugElisabeth NaschbergerRene JackstadtRudi BeyaertRaja AtreyaAnja A. KühlGregor SturmMiguel Gonzalez-AceraJay V. PatankarChristoph BeckerBritta SiegmundZlatko TrajanoskiBeate WinnerMarkus F. NeurathMichael SchumannClaudia Günther et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Normal lymphocyte homeostasis and function in MALT1 protease-resistant HOIL-1 knock-in mice

Ioannis SkordosYasmine DriegeMira HaegmanMarja KreikeJens StaalAnnelies DemeyerRudi Beyaert

A1 Journal Article in FEBS JOURNAL

CARD14 signalling ensures cell survival and cancer associated gene expression in prostate cancer cells

Domien VannesteJens StaalMira HaegmanYasmine DriegeMarieke CarelsElien Van NuffelPieter De BleserYvan SaeysRudi BeyaertInna Afonina

A1 Journal Article in BIOMEDICINES

Polo-like kinase 1 (PLK1) signaling in cancer and beyond

Stella IliakiRudi BeyaertInna Afonina

A1 Journal Article in BIOCHEMICAL PHARMACOLOGY