Research Explorer

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Project

Rol van peroxisomen in inflammatoire responsen

Outputs and Outcomes

Code

3G067512

Duration

01 January 2012 → 31 December 2017

Funding

Fonds voor Wetenschappelijk Onderzoek - Vlaanderen (FWO)

Promotor

Claus Bachert

Research disciplines

Medical and health sciences
- Immunology
- Respiratory medicine
- Immunology
- Respiratory medicine
- Immunology
- Respiratory medicine

Keywords

β-oxidation lipids peroxisomes

Project description

Peroxisomen zijn cellulaire organellen die de vorming en afbraak van bepaalde lipiden uitvoeren. We veronderstellen dat peroxisomale β-oxidatie kan interfereren met immuunreacties. Daarom zal de rol van het peroxisomale metabolisme in modelsystemen van neuronale inflammatieprocessen, chronische luchtwegontsteking en sepsis worden geanalyseerd. We zullen gebruik maken van algemene en conditionele MFP2-knockout muizen.

English

Dutch

English

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