Code
01D19621
Looptijd
01-10-2021 → 31-10-2021
Financiering
Regional and community funding: Special Research Fund
Promotor
Onderzoeksdisciplines
-
Natural sciences
- Infectious diseases
- Microbiomes
-
Medical and health sciences
- Drug discovery and development not elsewhere classified
Trefwoorden
Antibiotica
microfluidica
proteïne engineering
vancomycine-resistente enterococcen
Projectomschrijving
Lysins are bacteriophage-encoded peptidoglycan degrading enzymes with proven clinical potential as alternative for broad-spectrum antibiotics. In this project, I will develop a pipeline for discovery, engineering and delivery of lysins in the gut environment for pathogenic decolonization. A generic
approach will be elaborated for lysins, here specifically acting against vancomycin-resistant enterococci (VRE).