Acronym
PHF6
Code
3G086910
Duration
01 January 2010 → 31 December 2015
Funding
Research Foundation - Flanders (FWO)
Promotor
Research disciplines
-
Medical and health sciences
- Laboratory medicine
- Medical systems biology
- Pediatrics and neonatology
- Laboratory medicine
- Medical systems biology
- Molecular and cell biology
- Pediatrics and neonatology
- Nursing
- Laboratory medicine
- Medical systems biology
- Molecular and cell biology
- Pediatrics and neonatology
Keywords
T-ALL
Project description
T-ALL results from the malignant transformation of thymocytes and mainly affects children. Recently, PHF6 was identified as a novel tumor suppressor gene in T-ALL at the Center of Medical Genetics Ghent. The aim of this project is to investigate the role of PHF6 in the development of normal T-cells and T-ALL and to unravel transcriptional networks regulated by PHF6