Code
3S005016
Duration
01 January 2016 → 31 December 2019
Funding
Research Foundation - Flanders (FWO)
Promotor
Fellow
Research disciplines
-
Natural sciences
- (Bio)molecular modelling and design
- Regulation of metabolism
-
Medical and health sciences
- Physiological biophysics
- Regulation of metabolism
Keywords
recombinant proteins
biophysical studies
Cytokine-receptor complex
structural biology
Immunology
Project description
In light of the recently identified Th9 cell subset and the renewed interest in the IL-9 signalling complex, this project aims to provide structural and biophysical information to unravel the mechanistic principles underlying the assembly of IL-9-mediated signalling complexes. This will be done by using an integrative structural biology approach.