Research Explorer

Your browser does not support JavaScript or JavaScript is not enabled. Without JavaScript some functions of this webapplication may be disabled or cause error messages. To enable JavaScript, please consult the manual of your browser or contact your system administrator.

Project

Viral interference with RNA sensing and processing

Outputs & Impact

Publications & research data ( 16 )

Ultrapotent SARS coronavirus-neutralizing single-domain antibodies that clamp the spike at its base

Sieglinde De CaeInge Van MolleLoes van SchieSophie R. ShoemakerJulie DeckersNincy DebeufSahine LameireWim NerinckxKenny RooseDaria Fijalkowska et al.

A1 Journal Article in NATURE COMMUNICATIONS

MX2 forms nucleoporin-comprising cytoplasmic biomolecular condensates that lure viral capsids

Georgios MoschonasLouis DelhayeRobin CooremanFranziska HuesersAnayat BhatZoi StylianidouElien De BousserLaure De PryckHanna GrzesikDelphine De Sutter et al.

A1 Journal Article in CELL HOST & MICROBE

Integrating artificial intelligence-based epitope prediction in a SARS-CoV-2 antibody discovery pipeline : caution is warranted

Delphine Diana AcarWojciech WitkowskiMagdalena WejdaRuifang WeiTim DesmetBert SchepensSieglinde De CaeKoen SedeynHannah EeckhautDaria Fijalkowska et al.

A1 Journal Article in EBIOMEDICINE

JFH1-based Core-NS2 genotype variants of HCV with genetic stability in vivo and in vitro : important tools in the evaluation of virus neutralization

Laura CollignonKenn HolmbeckAshley JustLieven VerhoyeRodrigo Velázquez-MoctezumaUlrik FahnøeThomas H R CarlsenMansun LawJannick PrentoeTroels K H Scheel et al.

A1 Journal Article in HEPATOLOGY

Virus-host protein interaction network of the hepatitis E virus ORF2-4 by mammalian two-hybrid assays

Laura CorneillieIrma LemmensKarin WeeningAmse De MeyerFreya Van HoutteJan TavernierPhilip Meuleman

A1 Journal Article in VIRUSES-BASEL

The phosphatidylserine receptor TIM1 promotes infection of enveloped hepatitis E virus

Laura CorneillieIrma LemmensClaire MontpellierMartin FerriéKarin WeeningFreya Van HoutteXavier HanoulleLaurence CocquerelAli AmaraJan Tavernier et al.

A1 Journal Article in CELLULAR AND MOLECULAR LIFE SCIENCES

Comparison of HAV and HCV infections in vivo and in vitro reveals distinct patterns of innate immune evasion and activation

Ombretta ColasantiRani BurmHao-En HuangTobias RiedlJannik TrautNadine GillichTeng-Feng LiLaura CorneillieSuzanne Faure-DupuyOliver Grünvogel et al.

A1 Journal Article in JOURNAL OF HEPATOLOGY

Deep mutational scanning of proteins in mammalian cells

Stefanie MaesNick DeploeyFrank PeelmanSven Eyckerman

A2 Journal Article in CELL REPORTS METHODS

Novel prime-boost immune-based therapy inhibiting both hepatitis B and D virus infections

Rani BurmPanagiota MaraveliaGustaf AhlenSandra CiesekNoelia Caro PerezAnna PasettoStephan UrbanFreya Van HoutteLieven VerhoyeHeiner Wedemeyer et al.

A1 Journal Article in GUT

Human hepatocyte PNPLA3-148M exacerbates rapid non-alcoholic fatty liver disease development in chimeric mice

M KabbaniE MichailidisS SteenselsCG FulmerJM LunaJ Le PenM TardelliB RazookyI Ricardo-LaxC Zou et al.

A1 Journal Article in CELL REPORTS

Cov²MS : an automated and quantitative matrix-independent assay for mass spectrometric measurement of SARS-CoV-2 nucleocapsid protein

Bart Van PuyveldeKatleen Van UytfangheLaurence Van OudenhoveRalf GabrielsTessa Van RoyenArne MatthysMorteza RazaviRichard YipTerry PearsonNicolas Drouin et al.

A1 Journal Article in ANALYTICAL CHEMISTRY

An unexpected encounter : respiratory syncytial virus nonstructural protein 1 interacts with mediator subunit MED25

Tessa Van RoyenKoen SedeynGeorgios MoschonasWendy ToussaintM VuylstekeDelphi Van HaverFrancis ImpensSven EyckermanIrma LemmensJan Tavernier et al.

A1 Journal Article in JOURNAL OF VIROLOGY

A Hepatitis C virus genotype 1b post-transplant isolate with high replication efficiency in cell culture and its adaptation to infectious virus production in vitro and in vivo

Christian HeussPaul RothhaarRani BurmJi-Young LeePhilipp RalfsUta HaselmannLuisa J. StröhOmbretta ColasantiCong Si TranNoemi Schäfer et al.

A1 Journal Article in PLOS PATHOGENS

Viral interference of hepatitis C and E virus replication in novel experimental co-infection systems

T BurkardN ProskeK ResnerLaura CollignonL KnegendorfM FrieslandLieven VerhoyeIM SayedY BrüggemannMK Nocke et al.

A1 Journal Article in CELLS

How RSV proteins join forces to overcome the host innate immune response

Tessa Van RoyenIebe RosseyKoen SedeynBert SchepensXavier Saelens

A1 Journal Article in VIRUSES

Study of hepatitis E virus-4 infection in human liver-chimeric, immunodeficient, and immunocompetent mice

Laura CollignonLieven VerhoyeRenate Hakze-Van der HoningWim H. M. Van der PoelPhilip Meuleman

A1 Journal Article in FRONTIERS IN MICROBIOLOGY

Activities ( 0 )

Results

Impact narratives ( 0 )

Patents ( 0 )