Research Explorer

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Project

Looks don’t matter, it’s what you do that counts*: Deployment of innovative bio-assays for screening and elucidation of the mechanism of action of new psychoactive substances

Publications

In vitro functional assays as a tool to study new synthetic opioids at the mu-opioid receptor : potential, pitfalls and progress

Marthe VandeputteLakshmi VasudevanChristophe Stove

A1 Journal Article in PHARMACOLOGY & THERAPEUTICS

Pharmacological evaluation and forensic case series of N-pyrrolidino etonitazene (etonitazepyne), a newly emerging 2-benzylbenzimidazole 'nitazene' synthetic opioid

Marthe VandeputteAlex J. KrotulskiDonna WaltherGrant C. GlatfelterDonna PapsunSara E. WaltonBarry K. LoganMichael H. BaumannChristophe Stove

A1 Journal Article in ARCHIVES OF TOXICOLOGY

The rise and fall of isotonitazene and brorphine : two recent stars in the synthetic opioid firmament

Marthe VandeputteAlex J. KrotulskiDonna M. PapsunBarry K. LoganChristophe Stove

A1 Journal Article in JOURNAL OF ANALYTICAL TOXICOLOGY

Characterization of recent non-fentanyl synthetic opioids via three different in vitro mu-opioid receptor activation assays

Marthe VandeputteMattias PerssonDonna WaltherSvante VikingssonRobert KronstrandMichael H. BaumannHenrik GreenChristophe Stove

A1 Journal Article in ARCHIVES OF TOXICOLOGY

First identification, chemical analysis and pharmacological characterization of N-piperidinyl etonitazene (etonitazepipne), a recent addition to the 2-benzylbenzimidazole opioid subclass

Marthe VandeputteNick VerougstraeteDonna WaltherGrant C. GlatfelterJeroen MalflietMichael H. BaumannAlain VerstraeteChristophe Stove

A1 Journal Article in ARCHIVES OF TOXICOLOGY

Systematic evaluation of a panel of 30 synthetic cannabinoid receptor agonists structurally related to MMB-4en-PICA, MDMB-4en-PINACA, ADB-4en-PINACA, and MMB-4CN-BUTINACA using a combination of binding and different CB1 receptor activation assays-Part II: Structure activity relationship assessment via a beta-arrestin recruitment assay

Katharina GrafingerAnnelies CannaertAdam AmetovskiEric SparkesElizabeth CairnsSamuel D. BanisterVolker AuwarterChristophe Stove

A1 Journal Article in DRUG TESTING AND ANALYSIS

A novel nanobody-based bio-assay using functional complementation of a split nanoluciferase to monitor Mu- opioid receptor activation

Lakshmi VasudevanChristophe Stove

A1 Journal Article in ANALYTICAL AND BIOANALYTICAL CHEMISTRY