Research Explorer

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Project

Identification of miRNAs involved in hereditary breast cancer

Outputs and Outcomes

Code

365L4509

Duration

01 November 2009 → 31 October 2010

Funding

Funding by bilateral agreement (private and foundations)

Promotor

Anne De Paepe

Research disciplines

Natural sciences
- Genetics
- Systems biology
Medical and health sciences
- Molecular and cell biology
- Molecular and cell biology

Keywords

miRNAs BRCA1 breast cancer

Project description

This project aims to identify miRNAs involved in hereditary breast cancer. For those MiRNAs that are predicted to regulate genes involved in breast cancer pathogenesis, the presence of germline variants in the genomic regions around miRNA precursors will be evaluated. Detected variants will be further investigated with functional studies and segregation analysis.

English

Dutch

English

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