Identification of miRNAs involved in hereditary breast cancer

01 November 2009 → 31 October 2010
Funding by bilateral agreement (private and foundations)
Research disciplines
  • Natural sciences
    • Genetics
    • Systems biology
  • Medical and health sciences
    • Molecular and cell biology
    • Molecular and cell biology
miRNAs BRCA1 breast cancer
Project description

This project aims to identify miRNAs involved in hereditary breast cancer. For those MiRNAs that are predicted to regulate genes involved in breast cancer pathogenesis, the presence of germline variants in the genomic regions around miRNA precursors will be evaluated. Detected variants will be further investigated with functional studies and segregation analysis.