Duration
01 November 2009 → 31 October 2010
Funding
Funding by bilateral agreement (private and foundations)
Promotor
Research disciplines
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Natural sciences
- Genetics
- Systems biology
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Medical and health sciences
- Molecular and cell biology
- Molecular and cell biology
Keywords
miRNAs
BRCA1
breast cancer
Project description
This project aims to identify miRNAs involved in hereditary breast cancer. For those MiRNAs that are predicted to regulate genes involved in breast cancer pathogenesis, the presence of germline variants in the genomic regions around miRNA precursors will be evaluated. Detected variants will be further investigated with functional studies and segregation analysis.
