Project

microRNA profiling of multidrug resistant subpopulations in acute myeloid leukemia

Code
365I7809
Looptijd
01-01-2009 → 31-12-2012
Financiering
Funding by bilateral agreement (private and foundations)
Onderzoeksdisciplines
  • Natural sciences
    • Systems biology
  • Medical and health sciences
    • Hematology
    • Laboratory medicine
    • Morphological sciences
    • Oncology
    • Hematology
    • Laboratory medicine
    • Morphological sciences
    • Oncology
    • Hematology
    • Laboratory medicine
    • Morphological sciences
    • Oncology
Trefwoorden
AML MDR microRNA
 
Projectomschrijving
 

AML is difficult to treat and frequently relapses are observed which eventually cause a high rate of mortality. It is known that MDR plays an important role in the occurrence of these relapses. We wish to explore whether miroRNAs are relevant regulators of the MDR genes, causing resistant disease.