Project

Holistic and temporal analysis of gut-brain communication during chronic gut inflammation

Code
01D02119
Looptijd
15-11-2019 → 30-09-2022
Financiering
Regional and community funding: Special Research Fund
Onderzoeksdisciplines
  • Medical and health sciences
    • Applied immunology
    • Microbiome
    • Behavioural neuroscience
Trefwoorden
integratieve analyse Gastro-enterologie hersen-darm communicatie gedragswetenschappen
 
Projectomschrijving
 

The project aims at identifying the biological networks at the microbiome-gut-brain interface. Mouse models will be used for the identification of these networks, which are modulated in response to chronic gut inflammation. Furthermore, it will be determined whether these networks are causally involved in behavioural changes in colitic mice and in patients with inflammatory bowel disease treated for behavioral symptoms.