Project

Impact of Nef on dendritic to T cell transmission of HIV-1

Code
3F009411
Looptijd
01-10-2011 → 30-09-2015
Financiering
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Onderzoeksdisciplines
  • Natural sciences
    • Microbiology
    • Systems biology
  • Medical and health sciences
    • Immunology
    • Laboratory medicine
    • Microbiology
    • Immunology
    • Laboratory medicine
    • Microbiology
    • Immunology
    • Laboratory medicine
    • Microbiology
Trefwoorden
dendritische cellen HIV T cellen Nef transmissie
 
Projectomschrijving

The role of Nef in HIV transmission from dendritic cells to T cells will be researched. Both plain cell cultures as vaginal tissue explants will be used to study viral synapse formation and cytoskeleton dynamics in infection with wild-type or nef-mutated reporter viruses.