Project

Optimization of the single embryo transfer (SET) strategy in humans by group culture and proteomics of embryo-conditioned medium, based on the bovine embryo model.

Code
178DI0511
Duration
01 October 2010 → 05 January 2016
Funding
Regional and community funding: IWT/VLAIO
Research disciplines
  • Natural sciences
    • Animal biology
    • Genetics
  • Medical and health sciences
    • Endocrinology and metabolic diseases
    • Gynaecology and obstetrics
    • Molecular and cell biology
    • Morphological sciences
    • Endocrinology and metabolic diseases
    • Gynaecology and obstetrics
    • Molecular and cell biology
    • Morphological sciences
    • Nursing
    • Endocrinology and metabolic diseases
    • Gynaecology and obstetrics
    • Molecular and cell biology
    • Morphological sciences
  • Agricultural and food sciences
    • Veterinary medicine
Keywords
proteomics group culture humane in vitro embryo production
 
Project description

In vitro conditions can’t mimic the in vivo situation completely: in vivo embryos are exposed to autocrine, paracrine and endocrine factors. In vitro only autocrine factors remain, they are the cause of a better development during groupculture. In these project, we try to identify the autocrine factors and check if the supplementation of these factors improves the human culture medium.