Code
01T02712
Looptijd
01-02-2013 → 31-10-2014
Financiering
Regional and community funding: Special Research Fund
Promotor
Onderzoeksdisciplines
-
Medical and health sciences
- Immunology
- Otorhinolaryngology
- Respiratory medicine
- Immunology
- Microbiology
- Otorhinolaryngology
- Respiratory medicine
- Speech, language and hearing sciences
- Immunology
- Otorhinolaryngology
- Respiratory medicine
Trefwoorden
S. aureus
celdood
mitochondria
ontsteking
Projectomschrijving
The overall goal of this project is to analyze whether S. aureus could modulate mitochondrial biogenesis and cell death in human epithelial cells. Mitochondrial proteins will be analyzed by proteomics approach upon S. aureus infection of epihtelial cells. Next, mitochondrial proteins will be validated by knockdown studies. The consequent inflammatory response will be studied in human nasal mucosa explants.