Project

Study of ubiquitination of the key proteins in the jasmonate signal transduction cascades of the model plant Arabidopsis thaliana

Code

3G005212

Looptijd

01-01-2012 → 31-12-2017

Financiering

Research Foundation - Flanders (FWO)

Promotor

Alain Goossens

Onderzoeksdisciplines

Natural sciences
- Regulation of metabolism
- Cell signalling
- Posttranslational modifications
- Plant cell and molecular biology
- Plant immunology

Trefwoorden

ubiquitinatie E3-ligases jasmonaten

Projectomschrijving

We will study E3 Ubiquitin ligases from the model plant Arabidopsis thaliana that are putatively involved in jasmonate signalling. We aim to (1) identify their actual substrates, (2) acquire mechanistic insight in how they are regulated themselves,and interact and ubiquitinate these targets, and (3) phenotypically characterise Arabidopsis plants with altered expression in these E3 Ub ligases to establish their precise role at the whole plant level.