Research Explorer

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Tom Van Maerken

Publicaties & datasets

Prijzen & Erkenningen

35 Resultaten

2022

Exploration of neuroblastoma xenograft models for tumor extracellular RNA profiling in murine blood plasma

Vanessa VermeirssenJill DeleuAnnelien MorlionCeline EveraertJilke De WildeJasper AnckaertKaat DurinckJustine NuytensMuhammad RishfiFranki Speleman et al.

Whole transcriptome profiling of liquid biopsies from tumour xenografted mouse models enables specific monitoring of tumour-derived extracellular RNA

Vanessa VermeirssenJill DeleuAnnelien MorlionCeline EveraertJilke De WildeJasper AnckaertKaat DurinckJustine NuytensMuhammad RishfiFranki Speleman et al.

2021

A G316A polymorphism in the ornithine decarboxylase gene promoter modulates MYCN-driven childhood neuroblastoma

Laura D. GambleStefania PurgatoMichelle J. HendersonSimone Di GiacomoAmanda J. RussellPaolo PiginiJayne MurrayEmanuele ValliGiorgio MilazzoFederico M. Giorgi et al.

A1 Artikel in een tijdschrift in CANCERS

2019

A recurrent and transesophageal echocardiography-associated outbreak of extended-spectrum β-lactamase-producing Enterobacter cloacae complex in cardiac surgery patients

Tom Van MaerkenEls De BrabandereAudrey NoëlLiselotte CoorevitsPascal De WaegemaekerRaina AblorhStefaan BouchezINGRID HERCKHarlinde PeperstraetePierre Bogaerts et al.

A1 Artikel in een tijdschrift in ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL

ALK positively regulates MYCN activity through repression of HBP1 expression

Shana ClaeysGeertrui DeneckerKaat DurinckBieke DecaestekerLiselot MusSiebe LoontiensSuzanne VanhauwaertKristina AlthoffCaroline WigerupDaniel Bexell et al.

A1 Artikel in een tijdschrift in ONCOGENE

Cost-effective and robust genotyping using double-mismatch allele-specific quantitative PCR

Steve LefeverAli RihaniJoni Van der MeulenFilip PattynTom Van MaerkenJo Van DorpeJan HellemansJo Vandesompele

A1 Artikel in een tijdschrift in SCIENTIFIC REPORTS

Nosocomial outbreak of extended-spectrum β-lactamase-producing Enterobacter cloacae among cardiothoracic surgical patients : causes and consequences

A NoëlC VastradeS DupontM de BarsyTD HuangTom Van MaerkenIsabel Leroux-RoelsB DelaereL MellyB Rondelet et al.

A1 Artikel in een tijdschrift in JOURNAL OF HOSPITAL INFECTION

2018

Analytical and pre-analytical performance characteristics of a novel cartridge-type blood gas analyzer for point-of-care and laboratory testing

Matthijs OyaertTom Van MaerkenSILKE BRIDTSSilvi Van LoonHeleen LavergeVeronique Stove

A1 Artikel in een tijdschrift in CLINICAL BIOCHEMISTRY

Circulating microRNA biomarkers for metastatic disease in neuroblastoma patients

Fjoralba ZekaAnneleen DecockAlan Van GoethemKatrien VanderheydenFleur DemuynckTim LammensHetty HelsmoortelJoëlle VermeulenRosa NogueraAna P. Berbegall et al.

A1 Artikel in een tijdschrift in JCI INSIGHT

Circulating microRNA biomarkers for metastatic neuroblastoma

Fjoralba ZekaAlan Van GoethemTim LammensAnneleen DecockHetty HelsmoortelGenevieve LaureysMichael HogartyEveline BarbieriJason ShohetFrank Berthold et al.

Clinical burden of hepatitis E virus infection in a tertiary care center in Flanders, Belgium

Lien CattoirFREDERIK VAN HOECKETom Van MaerkenEline NysINGE RYCKAERTMatthias De BoulleAnja GeertsXavier VerhelstIsabelle ColleVeronik Hutse et al.

A1 Artikel in een tijdschrift in JOURNAL OF CLINICAL VIROLOGY

Longitudinal evaluation of murine serum microRNAs as biomarkers for neuroblastoma burden and therapeutic TP53 reactivation

Alan Van GoethemNurten YigitCeline EveraertMyrthala Moreno-SmithSanjeev A VasudevanFjoralba ZekaFleur DemunckEveline BarbieriFranki SpelemanPieter Mestdagh et al.

Meticulous plasma isolation is essential to avoid false low-level viraemia in Roche Cobas HIV-1 viral load assays

Virginie MortierLeen VancoillieKenny DauweDelfien StaelensEls DemecheleerMarlies SchauvliegeSylvie DinakisTom Van MaerkenGéraldine DessillyJean Ruelle et al.

A1 Artikel in een tijdschrift in ANTIVIRAL THERAPY

Performance of the preanalytical check module of the Stago STA R Max2 mechanical endpoint detection analyzer for assessing the impact of hemolysis, lipemia, and icterus on aPTT and PT

LISA FLORINMatthijs OyaertTom Van MaerkenKatrien Devreese

A1 Artikel in een tijdschrift in INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY

Pharmacological restoration of tumour suppressor protein p53 in neuroblastoma : seeking synergy and non-invasive biomarkers

Alan Van GoethemJo VandesompeleTom Van Maerken

A2 Artikel in een tijdschrift in BELGIAN JOURNAL OF MEDICAL ONCOLOGY

The ornithine decarboxylase G316A promoter polymorphism impacts neuroblastoma clinical outcome and may identify patients particularly susceptible to polyamine inhibition

Laura GambleStefania PurgatoSimone Di GiacomoAmanda RussellPaolo PiginiEmanuele ValliLesley AshtonTom Van MaerkenJo VandesompeleRogier Versteeg et al.

Thorough in silico and in vitro cDNA analysis of 21 putative BRCA1 and BRCA2 splice variants and a complex tandem duplication in BRCA2 allowing the identification of activated cryptic splice donor sites in BRCA2 exon 11

Annelot BaertEva MachackovaIlse CoeneCarol CreminKristin TurnerCheryl Portigal-ToddMarie Jill AsratJennifer NukAllison MindlinSean Young et al.

A1 Artikel in een tijdschrift in HUMAN MUTATION

2017

Accelerating drug development for neuroblastoma - New drug development strategy : an Innovative Therapies for Children with Cancer, European Network for Cancer Research in Children and Adolescents and International Society of Paediatric Oncology Europe Neuroblastoma project

Lucas MorenoHubert CaronBirgit GeoergerAngelika EggertGudrun SchleiermacherPenelope BrockDominique Valteau-CouanetLouis CheslerJohannes SchulteKatleen De Preter et al.

A1 Artikel in een tijdschrift in EXPERT OPINION ON DRUG DISCOVERY

Analytical and diagnostic performance evaluation of the new Sysmex UF-5000 for automated urine sediment analysis

Matthijs OyaertRuben GovaertJoris DelangheVeronique StoveTom Van Maerken

Identifying familial hypercholesterolemia in pediatric and adult patients : is screening relevant in a tertiary care setting?

Timothy CammaertMatthijs OyaertErnst RietzschelJean De SchepperTom Van MaerkenVeronique Stove

MicroRNA expression analysis using small RNA sequencing discovery and RT-qPCR-based validation

Alan Van GoethemPieter MestdaghTom Van MaerkenJo Vandesompele

Hoofdstuk in een boek in Functional genomics : methods and protocols

The HBP1 tumor suppressor is a negative epigenetic regulator of MYCN driven neuroblastoma through interaction with the PRC2 complex

Geertrui DeneckerShana ClaeysIrina LambertzEls JanssensSuzanne VanhauwaertBieke DecaestekerTom Van MaerkenBram De WildeGenevieve LaureysKristina Althoff et al.

2016

Evaluation of the role of germline RECQL variants in Belgian patients referred for genetic testing in the context of familial breast/ovarian cancer

Greet WiemeIlse CoeneLiselotte VergoteBruce PoppeFransiska MalfaitTom Van MaerkenKim De LeeneerKathleen Claes

2015

The HBP1 tumour suppressor at multiple regulatory cross roads in neuroblastoma

Shana ClaeysIrina LambertzAlan Van GoethemAnneleen BeckersCandy KumpsTom Van MaerkenJohannes SchulteKatleen De PreterFranki Speleman

Upregulation of MAPK negative feedback regulators and RET in mutant ALK neuroblastoma : implications for targeted treatment

Irina LambertzCandy KumpsShana ClaeysSven LindnerAnneleen BeckersEls JanssensDaniel CarterAlex CazesBelamy CheungMarilena De Mariano et al.

Upregulation of MAPK negative feedback regulators and RET in mutant ALK neuroblastoma : implications for targeted treatment

Irina LambertzCandy KumpsShana ClaeysSven LindnerAnneleen BeckersEls JanssensDaniel CarterAlex CazesBelamy CheungMarilena De Mariano et al.

Upregulation of MAPK negative feedback regulators and RET in mutant ALK neuroblastoma : implications for targeted treatment

Irina LambertzCandy KumpsShana ClaeysSven LindnerAnneleen BeckersEls JanssensDaniel CarterAlex CazesBelamy CheungMarilena De Mariano et al.

2014

CASP8 SNP D302H (rs1045485) is associated with worse survival in MYCN-amplified neuroblastoma patients

Ali RihaniBram De WildeFjoralba ZekaGenevieve LaureysNadine FrancotteGian Paolo ToniniSimona CocoRogier VersteegRosa NogueraJohannes Schulte et al.

CASP8 SNP D302H (rs1045485) is associated with worse survival in MYCN-amplified neuroblastoma patients

Ali RihaniBram De WildeFjoralba ZekaGenevieve LaureysNadine FrancotteGian Paolo ToniniSimona CocoRogier VersteegRosa NogueraJohannes Schulte et al.

Evaluation of targeted drugs in combination with the MDM2 antagonist RG7388 in neuroblastoma

Alan Van GoethemGwen NicholsFranki SpelemanJo VandesompeleTom Van Maerken

Evaluation of targeted drugs in combination with the MDM2 antagonist RG7388 in neuroblastoma

Alan Van GoethemGwen NicholsFranki SpelemanJo VandesompeleTom Van Maerken

Targeted analysis of TP53 pathway SNPs in neuroblastoma patients

Ali RihaniBram De WildeFjoralba ZekaGenevieve LaureysNadine FrancotteGian Paolo ToniniSimona CocoRogier VersteegRosa NogueraJohannes Schulte et al.

The G2 micronucleus assay for the analysis of in vitro chromosomal radiosensitivity in individuals carrying a BRCA1 or BRCA2 mutation

Annelot BaertJulie DepuydtBruce PoppeTom Van MaerkenFransiska MalfaitTim Van DammeSylvia De NobeleKim De LeeneerKathleen ClaesAnne Vral

2010

An integrative genomics screen uncovers ncRNA T-UCR functions in neuroblastoma tumours

Pieter MestdaghE FredlundFilip PattynAli RihaniTom Van MaerkenJoëlle VermeulenCandy KumpsBjörn MentenKatleen De PreterA Schramm et al.

A1 Artikel in een tijdschrift in ONCOGENE

2009

Meta-mining of Neuroblastoma and Neuroblast Gene Expression Profiles Reveals Candidate Therapeutic Compounds

Katleen De PreterSara De BrouwerTom Van MaerkenFilip PattynA SchrammA EggertJo VandesompeleFranki Speleman

A1 Artikel in een tijdschrift in CLINICAL CANCER RESEARCH