Research Explorer

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Researcher

Tine Wyckhuys

Awards & Distinctions

53 Results

2012

Poisson distributed deep brain stimulation (DBS) in the ventral hippocampal commissure suppresses seizures in the kainic acid rat model

Bregt Van NieuwenhuyseJoke ParthoensTine WyckhuysRobrecht RaedtWytse WadmanPaul BoonKristl Vonck

2011

Automatic detection of epileptic seizures on the intra-cranial electroencephalogram of rats using reservoir computing

Pieter ButeneersDavid VerstraetenPieter van MierloTine WyckhuysDirk StroobandtRobrecht RaedtHans HallezBenjamin Schrauwen

A1 Journal Article in ARTIFICIAL INTELLIGENCE IN MEDICINE

Increased hippocampal noradrenaline is a biomarker for efficacy of vagus nerve stimulation in a limbic seizure model

Robrecht RaedtRalf ClinckersLies MolletKristl VonckRiëm El TahryTine WyckhuysVeerle De HerdtEvelien CarretteWyste WadmanYvette Michotte et al.

A1 Journal Article in JOURNAL OF NEUROCHEMISTRY

Repeated assessment of larynx compound muscle action potentials using a self-sizing cuff electrode around the vagus nerve in experimental rats

Riëm El TahryLies MolletRobrecht RaedtJean DelbekeVeerle De HerdtTine WyckhuysDimitri HemelsoetAlfred MeursKristl VonckWytse Wadman et al.

A1 Journal Article in JOURNAL OF NEUROSCIENCE METHODS

2010

A novel implantable vagus nerve stimulation system (ADNS-300) for combined stimulation and recording of the vagus nerve: pilot trial at Ghent University Hospital

Riëm El TahryRobrecht RaedtLies MolletVeerle De HerdtTine WyckhuysAnnelies Van DyckeAlfred MeursFrank DewaeleDirk Van RoostPatrick Doguet et al.

A1 Journal Article in EPILEPSY RESEARCH

Comparison of hippocampal Deep Brain Stimulation with high (130 Hz) and low frequency (5 Hz) on afterdischarges in kindled rats

Tine WyckhuysRobrecht RaedtKristl VonckWytse WadmanPaul Boon

A1 Journal Article in EPILEPSY RESEARCH

Continuous local intrahippocampal delivery of adenosine reduces seizure frequency in rats with spontaneous seizures

Annelies Van DyckeRobrecht RaedtIne DauweTom SanteTine WyckhuysAlfred MeursKristl VonckWytse WadmanPaul Boon

A1 Journal Article in EPILEPSIA

Hippocampal deep brain stimulation induces decreased rCBF in the hippocampal formation of the rat

Tine WyckhuysSteven StaelensBregt Van NieuwenhuyseSteven DeleyeHans HallezKristl VonckRobrecht RaedtWytse WadmanPaul Boon

A1 Journal Article in NEUROIMAGE

Hippocampal deep brain stimulation reveals decreased rCBF in the hippocampus of the rat: a mu spect study

Tine WyckhuysBregt Van NieuwenhuyseSteven StaelensSteven DeleyeHans HallezKristl VonckWytse WadmanPaul Boon

Modulation of seizure threshold by vagus nerve stimulation in an animal model for motor seizures

Veerle De HerdtJan De WaeleRobrecht RaedtTine WyckhuysRiëm El TahryKristl VonckWytse WadmanPaul Boon

A1 Journal Article in ACTA NEUROLOGICA SCANDINAVICA

Suppression of hippocampal epileptic seizures in the kainate rat by Poisson distributed stimulation

Tine WyckhuysPaul BoonRobrecht RaedtBregt Van NieuwenhuyseKristl VonckWytse Wadman

A1 Journal Article in EPILEPSIA

2009

A multimodal post processing framework for activation studies of the rat brain

Steven StaelensTine WyckhuysSteven DeleyeHans HallezStefaan VandenbergheBregt Van NieuwenhuyseKristl Vonck

Adenosine secretion by neural stem cells isolated from ADK-/- mice

Annelies Van DyckeRobrecht RaedtDetlev BoisonAlain VerstraeteAlfred MeursTine WyckhuysRiëm El TahryKristl VonckWytse WadmanPaul Boon

Anti-epileptic effects of vagus nerve stimulation in the focal pilocarpine model

Lies MolletRalph ClinckersRobrecht RaedtAlfred MeursTine WyckhuysAnnelies Van DyckeRiëm El TahryKristl VonckWytse WadmanYvette Michotte et al.

Anti-epileptic effects of vagus nerve stimulation in the focal pilocarpine model

Robrecht RaedtRalph ClinckersLies MolletAlfred MeursTine WyckhuysRiëm El TahryKristl VonckY MichottePaul BoonI Smolders

Deep Brain Stimulation for epilepsy: knowledge gained from experimental animal models

Tine WyckhuysPieter-Jan GeertsRobrecht RaedtKristl VonckWytse WadmanPaul Boon

A1 Journal Article in ACTA NEUROLOGICA BELGICA

EFFECT OF ACUTE AND LONG-TERM VAGUS NERVE STIMULATION IN FULLY KINDLED RATS

Robrecht RaedtL. WaterschootTine WyckhuysVeerle De HerdtRiëm El TahryJ. DelbekeKristl VonckWytse WadmanPaul Boon

Effect of hippocampal deep brain stimulation on blood perfusion evaluated by SPECT

Bregt Van NieuwenhuyseTine WyckhuysRobrecht RaedtAlfred MeursAnnelies Van DyckeRiëm El TahryKristl VonckWytse WadmanSteven DeleyeSteven Staelens et al.

Electrical Stimulation for the Treatment of Epilepsy

Paul BoonRobrecht RaedtVeerle De HerdtTine WyckhuysKristl Vonck

A1 Journal Article in Neurotherapeutics

HIPPOCAMPAL HIGH FREQUENCY DEEP BRAIN STIMULATION REDUCES SEIZURE FREQUENCY IN THE KAINIC ACID MODEL

Tine WyckhuysRobrecht RaedtKristl VonckWytse WadmanPaul Boon

High resolution mu SPECT for brain activation analysis in small animals

Steven StaelensTine WyckhuysSteven DeleyeHans HallezStefaan VandenbergheBert Van NieuwenhuyseKim Vonck

Identification of a brainstem evoked potential following cervical vagus nerve stimulation in rats

Riëm El TahryRobrecht RaedtVeerle De HerdtLiesbeth WaterschootTine WyckhuysAnnelies Van DyckeAlfred MeursKristl VonckWytse WadmanPaul Boon

In vivo measurements of vagus nerve compound action potentials in experimental rats

Riëm El TahryRobrecht RaedtVeerle De HerdtAnnelies Van DyckeTine WyckhuysAlfred MeursJean DelbekeKristl VonckWytse WadmanPaul Boon

Increased rat serum corticosterone suggests immunomodulation by stimulation of the vagal nerve

Veerle De HerdtLeen PuimègeJan De WaeleRobrecht RaedtTine WyckhuysRiëm El TahryClaude LibertWytse WadmanPaul BoonKristl Vonck

A1 Journal Article in JOURNAL OF NEUROIMMUNOLOGY

Local infusion of neuropeptide Y has anti-epileptic effects in fully kindled rats

Ine DauweRobrecht RaedtAnnelies Van DyckeAlfred MeursTine WyckhuysRiëm El TahryKristl VonckWytse WadmanPaul Boon

Local infusion of neuropeptide Y has anti-epileptic effects in kindled rats

Paul BoonIne DauweAnnelies Van DyckeAlfred MeursTine WyckhuysWytse WadmanRobrecht RaedtKristl Vonck

Seizures in the intrahippocampal kainic acid epilepsy model: characterization using long-term video-EEG monitoring in the rat

Robrecht RaedtAnnelies Van DyckeD. Van MelkebekeTim De SmedtP. ClaeysTine WyckhuysKristl VonckWytse WadmanPaul Boon

A1 Journal Article in Acta Neurologica Scandinavica

Unconditioned adult-derived neurosphere cells mainly differentiate towards astrocytes upon transplantation in sclerotic rat hippocampus

Robrecht RaedtAnnelies Van DyckeAnouk WaeytensTine WyckhuysKristl VonckWytse WadmanPaul Boon

A1 Journal Article in EPILEPSY RESEARCH

2008

Deep Brain Stimulation in experimental animal models of epilepsy

Tine WyckhuysPaul Boon

Efficacy of low and high frequency Deep Brain Stimulation in epilepsy

Paul BoonTine Wyckhuys

High frequency stimulation in the hippocampus reduces the frequency of seizures in kainic acid injected rats

Bregt Van NieuwenhuyseTine WyckhuysRobrecht RaedtKristl VonckPaul BoonWytse Wadman

LOCAL DELIVERY OF ADENOSINE HAS AN ANTIEPILEPTIC EFFECT IN RATS WITH SPONTANEOUS SEIZURES

Annelies Van DyckeRobrecht RaedtI DauweTine WyckhuysVeerle De HerdtRiëm El TahryAlfred MeursKristl VonckWytse WadmanPaul Boon

Vagus nerve and hippocampal stimulation for refractory epilepsy

Paul BoonVeerle De HerdtKristl VonckAnnelies Van DyckeTine WyckhuysL WaterschootRiëm El TahryDirk Van RoostRobrecht RaedtWytse Wadman

Bookchapter in Seizure Prediction in Epilepsy, from basic mechanisms to clinical applications

Vagus nerve compound action potentials (CAPs) verify vagus nerve stimulation in rats

Liesbeth WaterschootRobrecht RaedtTim De SmedtTine WyckhuysVeerle De HerdtAnnelies Van DyckeJean DelbekeKristl VonckWytse WadmanPaul Boon

2007

Adult-derived neural stem cells differentiate mainly towards astrocytes upon transplantation in the sclerotic hippocampus of a model for temporal lobe epilepsy

Robrecht RaedtAnnelies Van DyckeTine WyckhuysKristl VonckWytse WadmanLuc LeybaertPaul Boon

Comparison of high and low frequency hippocampal deep brain stimulation in kindled rats

Tine WyckhuysTim De SmedtRobrecht RaedtLiesbeth WaterschootKristl VonckWytse WadmanPaul Boon

High frequency deep brain stimulation in the hippocampus modifies seizure characteristics in kindled rats

Tine WyckhuysTim De SmedtPieter ClaeysRobrecht RaedtLiesbeth WaterschootKristl VonckCaroline Van den broeckeCyriel MabildeLuc LeybaertWytse Wadman et al.

A1 Journal Article in EPILEPSIA

Low dose, whole brain radiation suppresses hippocampal neurogenesis and accelerates kindling epileptogenesis

Robrecht RaedtAnnelies Van DyckeAnn-Marie AlbornTom BoterbergTim De SmedtTine WyckhuysVeerle De HerdtLiesbeth WaterschootKristl VonckPeter Eriksson et al.

Measuring compound action potentials (CAPS) verifies vagus nerve stimulation (VNS) in rats

Liesbeth WaterschootRobrecht RaedtTim De SmedtTine WyckhuysVeerle De HerdtAnnelies Van DyckeJ DELBEKEKristl VonckWytse WadmanPaul Boon

Serial day rapid kindling is an effective tool in screening the anti-epileptic properties of topiramate

Tim De SmedtSoetkin De RouckRobrecht RaedtTine WyckhuysLiesbeth WaterschootVeerle De HerdtAnnelies Van DyckeRiëm El TahryKristl VonckPaul Boon

A1 Journal Article in SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Serial day rapid kindling is an effective tool in screening the anti-epileptic properties of topiramate

Tim De SmedtSoetkin De RouckRobrecht RaedtTine WyckhuysLiesbeth WaterschootVeerle De HerdtAnnelies Van DyckeRiëm El TahryKristl VonckPaul Boon

Vagus nerve stimulation in the rat hippocampal kindling model

Liesbeth WaterschootRobrecht RaedtTim De SmedtTine WyckhuysJ DelbekeKristl VonckWytse WadmanPaul Boon

Vagus nerve stimulation induced changes in corticosterone in rats

Veerle De HerdtClaude LibertJAN DE WAELET DE SMEDTL WATERSCHOOTTine WyckhuysRiëm El TahryAnnelies Van DyckeRobrecht RaedtKristl Vonck et al.

2006

Characterisation of the intrahippocampal kainic acid status epilepticus model using longterm video-EEG monitoring

Annelies Van DyckeRobrecht RaedtDeborah Van MelkebekeTim De SmedtTine WyckhuysLiesbeth WaterschootVeerle De HerdtKristl VonckPaul Boon

High frequency deep brain stimulation of the hippocampus in a rat model for temporal lobe epilepsy

Tine WyckhuysP CLAEYSRobrecht RaedtTim De SmedtLiesbeth WaterschootCaroline Van den broeckeCyriel MabildeLuc LeybaertWytse WadmanPaul Boon

Low-dose whole brain gamma-irradiation accelerates epileptogenesis during hippocampal kindling

Robrecht RaedtAnnelies Van DyckeTom BoterbergAM ALBORNTim De SmedtTine WyckhuysVeerle De HerdtLiesbeth WaterschootKristl VonckP ERIKSSON et al.

Neuromodulation with levetiracetam and vagus nerve stimulation in experimental animal models of epilepsy

Stefanie DedeurwaerdereKristl VonckVeerle De HerdtLiesbeth WaterschootTim De SmedtRobrecht RaedtTine WyckhuysB LEGROSPeter Van HeseK VAN LAERE et al.

A1 Journal Article in ACTA NEUROLOGICA BELGICA

Stimulation of the anterodorsal thalamus in genetic absence epilepsy rats from strasbourg (GAERS)

Liesbeth WaterschootStefanie DedeurwaerdereTine WyckhuysPeter Van HeseRobrecht RaedtTim De SmedtCaroline Van den broeckeKristl VonckWytse WadmanPaul Boon

2005

Antiepileptic and antiepileptogenic properties of levetiracetam in rapid kindling

Tim De SmedtRobrecht RaedtPieter ClaeysStefanie DedeurwaerdereB LEGROSSTine WyckhuysKristl VonckPaul Boon

Antiepileptic and antiepileptogenic properties of levetiracetam in rapid kindling

Tim De SmedtRobrecht RaedtPieter ClaeysStefanie DedeurwaerdereB LEGROSSTine WyckhuysKristl VonckPaul Boon

Antiepileptic and antiepileptogenic properties of levetiracetam in rapid kindling

Tim De SmedtRobrecht RaedtPieter ClaeysStefanie DedeurwaerdereB LEGROSSTine WyckhuysKristl VonckPaul Boon

Rapid kindling in preclinical anti-epileptic drug development: The effect of levetiracetam

Tim De SmedtKristl VonckRobrecht RaedtStefanie DedeurwaerderePieter ClaeysB LEGROSTine WyckhuysWytse WadmanPaul Boon

A1 Journal Article in EPILEPSY RESEARCH

Towards a cell therapy for temporal lobe epilepsy (TLE)?

Tine WyckhuysRobrecht RaedtPieter ClaeysTim De SmedtJozef PinxterenDavid CraeyeKaatje SmitsKristl VonckStefanie DedeurwaerdereAnouk Waeytens et al.