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Researcher
Stefaan De Smedt
Profile
Projects
Publications
Activities
433
Results
2021
Bubble forming films for spatial selective cell killing
Dawei Hua
Aranit Harizaj
Mike Wels
Toon Brans
Stephan Stremersch
Herlinde De Keersmaecker
Eduardo Bolea Fernandez
Frank Vanhaecke
Dimitri Roels
Kevin Braeckmans
Ranhua Xiong
Chaobo Huang
Stefaan De Smedt
Félix Sauvage
A1
Journal Article
in
ADVANCED MATERIALS
2021
Carbon quantum dots as a dual platform for the inhibition and light-based destruction of collagen fibers : implications for the treatment of eye floaters
Alexandre Barras
Félix Sauvage
Inès De Hoon
Kevin Braeckmans
Dawei Hua
Gaëtan Buvat
Juan Fraire
Christophe Lethien
J. Sebag
Michael Harrington
Amar Abderrahmani
Rabah Boukherroub
Stefaan De Smedt
Sabine Szunerits
A1
Journal Article
in
NANOSCALE HORIZONS
2021
Challenges and strategies for the delivery of biologics to the cornea
Mike Wels
D. Roels
Koen Raemdonck
Stefaan De Smedt
Félix Sauvage
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2021
Concentration gradients in material sciences : methods to design and biomedical applications
Dawei Hua
Ranhua Xiong
Kevin Braeckmans
Benoit Scheid
Chaobo Huang
Félix Sauvage
Stefaan De Smedt
A1
Journal Article
in
ADVANCED FUNCTIONAL MATERIALS
2021
Cytosolic delivery of gadolinium via photoporation enables improved in vivo magnetic resonance imaging of cancer cells
Aranit Harizaj
Benedicte Descamps
Christophe Mangodt
Stephan Stremersch
Arianna Stoppa
Lieve Balcaen
Toon Brans
Hilde De Rooster
Nausikaa Devriendt
Juan Fraire
Eduardo Bolea Fernandez
Olivier De Wever
Wouter Willaert
Frank Vanhaecke
Christian Stevens
Stefaan De Smedt
Bart Roman
Christian Vanhove
Ine Lentacker
Kevin Braeckmans
A1
Journal Article
in
BIOMATERIALS SCIENCE
2021
Delivering on the promise of adoptive T cell therapy : assessment of non-viral methods for direct cytosolic delivery of membrane-impermeable cargo
Jelter Van Hoeck
Koen Raemdonck
Stefaan De Smedt
Dissertation
2021
Enhanced siRNA delivery and selective apoptosis induction in H1299 cancer cells by layer-by-layer-assembled Se nanocomplexes : toward more efficient cancer therapy
Maryam Sharifiaghdam
Elnaz Shaabani Sichani
Zeynab Sharifiaghdam
Herlinde De Keersmaecker
Riet De Rycke
Stefaan De Smedt
Reza Faridi-Majidi
Kevin Braeckmans
Juan Fraire
A1
Journal Article
in
FRONTIERS IN MOLECULAR BIOSCIENCES
2021
Hydrogel-induced cell membrane disruptions enable direct cytosolic delivery of membrane-impermeable cargo
Jelter Van Hoeck
Thijs Van de Vyver
Aranit Harizaj
Glenn Goetgeluk
Pieterjan Merckx
Jing Liu
Mike Wels
Félix Sauvage
Herlinde De Keersmaecker
Christian Vanhove
Olivier G. de Jong
Pieter Vader
Heleen Dewitte
Bart Vandekerckhove
Kevin Braeckmans
Stefaan De Smedt
Koen Raemdonck
A1
Journal Article
in
ADVANCED MATERIALS
2021
Layer by layer assembled chitosan-coated gold nanoparticles for enhanced siRNA delivery and silencing
Elnaz Shaabani Sichani
Maryam Sharifiaghdam
Herlinde De Keersmaecker
Riet De Rycke
Stefaan De Smedt
Reza Faridi-Majidi
Kevin Braeckmans
Juan Fraire
A1
Journal Article
in
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2021
Lipoplexes to deliver oligonucleotides in gram-positive and gram-negative bacteria : towards treatment of blood infections
Sara Pereira
Rita Sobral Santos
Luís Moreira
Nuno Guimarães
Mariana Gomes
Heyang Zhang
Katrien Remaut
Kevin Braeckmans
Stefaan De Smedt
Nuno Filipe Azevedo
A1
Journal Article
in
PHARMACEUTICS
2021
Nanoparticle-sensitized photoporation enables inflammasome activation studies in targeted single cells dagger
Aranit Harizaj
Filip Van Hauwermeiren
Stephan Stremersch
Riet De Rycke
Herlinde De Keersmaecker
Toon Brans
Juan Fraire
Karolien Grauwen
Stefaan De Smedt
Ine Lentacker
Mohamed Lamkanfi
Kevin Braeckmans
A1
Journal Article
in
NANOSCALE
2021
Old drugs with new tricks : repurposing small molecules to promote lysosomal escape of small nucleic acid therapeutics
Thijs Van de Vyver
Koen Raemdonck
Stefaan De Smedt
Dissertation
2021
PEGylation of recombinant human deoxyribonuclease I decreases its transport across lung epithelial cells and uptake by macrophages
Sohaib Mahri
Eléonore Hardy
Tobias Wilms
Herlinde De Keersmaecker
Kevin Braeckmans
Stefaan De Smedt
Cynthia Bosquillon
Rita Vanbever
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2021
Photoporation with biodegradable polydopamine nanosensitizers enables safe and efficient delivery of mRNA in human T cells
Aranit Harizaj
Mike Wels
Laurens Raes
Stephan Stremersch
Glenn Goetgeluk
Toon Brans
Bart Vandekerckhove
Félix Sauvage
Stefaan De Smedt
Ine Lentacker
Kevin Braeckmans
A1
Journal Article
in
ADVANCED FUNCTIONAL MATERIALS
2021
Physical transfection technologies for macrophages and dendritic cells in immunotherapy
Aranit Harizaj
Stefaan De Smedt
Ine Lentacker
Kevin Braeckmans
A1
Journal Article
in
EXPERT OPINION ON DRUG DELIVERY
2021
Surfactant protein B promotes cytosolic SiRNA delivery by adopting a virus-like mechanism of action
Roberta Guagliardo
Lore Herman
Jelle Penders
Agata Zamborlin
Herlinde De Keersmaecker
Thijs Van de Vyver
Sandrine Verstraeten
Pieterjan Merckx
Marie-Paule Mingeot-Leclercq
Mercedes Echaide
Jesus Perez-Gil
Molly M. Stevens
Stefaan De Smedt
Koen Raemdonck
A1
Journal Article
in
ACS NANO
2021
Vaccinia virus protein B18R : influence on mRNA immunogenicity and translation upon non-viral delivery in different ocular cell types
An-Katrien Minnaert
Joke Devoldere
Karen Peynshaert
Laure Vercruysse
Stefaan De Smedt
Katrien Remaut
A1
Journal Article
in
PHARMACEUTICS
2021
2020
Beyond the surface : unraveling the intracellular mechanism behind surfactant protein B (SP-B) mediated siRNA delivery
Roberta Guagliardo
Koen Raemdonck
Stefaan De Smedt
Dissertation
2020
Faithful fabrication of biocompatible multicompartmental memomicrospheres for digitally color‐tunable barcoding
Guosheng Tang
Long Chen
Zixuan Wang
Shuting Gao
Qingli Qu
Ranhua Xiong
Kevin Braeckmans
Stefaan De Smedt
Yu Shrike Zhang
Chaobo Huang
A1
Journal Article
in
SMALL
2020
Fluorescence-based quantification of messenger RNA and plasmid DNA decay kinetics in extracellular biological fluids and cell extracts
Heyang Zhang
Koen Rombouts
Laurens Raes
Ranhua Xiong
Stefaan De Smedt
Kevin Braeckmans
Katrien Remaut
A1
Journal Article
in
ADVANCED BIOSYSTEMS
2020
Influence of pathogenic stimuli on Müller cell transfection by lipoplexes
Karen Peynshaert
Joke Devoldere
Frederik Philips
Fauve Vergauwe
Stefaan De Smedt
Katrien Remaut
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
2020
Intracellular delivery of mRNA in adherent and suspension cells by vapor nanobubble photoporation
Laurens Raes
Stephan Stremersch
Juan Fraire
Toon Brans
Glenn Goetgeluk
Stijn De Munter
Lien Van Hoecke
Rein Verbeke
Jelter Van Hoeck
Ranhua Xiong
Xavier Saelens
Bart Vandekerckhove
Stefaan De Smedt
Koen Raemdonck
Kevin Braeckmans
A1
Journal Article
in
NANO-MICRO LETTERS
2020
Intracellular labeling with extrinsic probes : delivery strategies and applications
Jing Liu
Juan Fraire
Stefaan De Smedt
Ranhua Xiong
Kevin Braeckmans
A1
Journal Article
in
SMALL
2020
Long-term live-cell microscopy with labeled nanobodies delivered by laser-induced photoporation
Jing Liu
Tim Hebbrecht
Toon Brans
Eef Parthoens
Saskia Lippens
Chengnan Li
Herlinde De Keersmaecker
Winnok H. De Vos
Stefaan De Smedt
Rabah Boukherroub
Jan Gettemans
Ranhua Xiong
Kevin Braeckmans
A1
Journal Article
in
NANO RESEARCH
2020
Lung surfactant-hydrogel nanocomposites for pulmonary siRNA delivery : breaching barriers for nanomedicine-based inhalation therapy
Pieterjan Merckx
Koen Raemdonck
Stefaan De Smedt
Dissertation
2020
Lyophilization and nebulization of pulmonary surfactant-coated nanogels for siRNA inhalation therapy
Pieterjan Merckx
Joris Lammens
Gust Nuytten
Bram Bogaert
Roberta Guagliardo
Tania Maes
Chris Vervaet
Thomas De Beer
Stefaan De Smedt
Koen Raemdonck
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
2020
Materials and technologies to combat counterfeiting of pharmaceuticals : current and future problem tackling
Heyang Zhang
Dawei Hua
Chaobo Huang
Sangram Keshari Samal
Ranhua Xiong
Félix Sauvage
Kevin Braeckmans
Katrien Remaut
Stefaan De Smedt
A1
Journal Article
in
ADVANCED MATERIALS
2020
Nanomaterials to avoid and destroy protein aggregates
Félix Sauvage
Joost Schymkowitz
Frederic Rousseau
Bela Z. Schmidt
Katrien Remaut
Kevin Braeckmans
Stefaan De Smedt
A1
Journal Article
in
NANO TODAY
2020
Ocular barriers to retinal delivery of intravitreal liposomes : impact of vitreoretinal interface
Shirin Tavakoli
Karen Peynshaert
Tatu Lajunen
Joke Devoldere
Eva M. del Amo
Marika Ruponen
Stefaan De Smedt
Katrien Remaut
Arto Urtti
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2020
Surface functionalization with polyethylene glycol and polyethyleneimine improves the performance of graphene-based materials for safe and efficient intracellular delivery by laser-induced photoporation
Jing Liu
Chengnan Li
Toon Brans
Aranit Harizaj
Shana Van de Steene
Thomas De Beer
Stefaan De Smedt
Sabine Szunerits
Rabah Boukherroub
Ranhua Xiong
Kevin Braeckmans
A1
Journal Article
in
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2020
Synergy between intraperitoneal aerosolization (PIPAC) and cancer nanomedicine : cisplatin-loaded polyarginine-hyaluronic acid nanocarriers efficiently eradicate peritoneal metastasis of advanced human ovarian cancer
Molood Shariati
Giovanna Lollo
Kevin Matha
Benedicte Descamps
Christian Vanhove
Leen Van de Sande
Wouter Willaert
Lieve Balcaen
Frank Vanhaecke
Jean-Pierre Benoit
Wim Ceelen
Stefaan De Smedt
Katrien Remaut
A1
Journal Article
in
ACS APPLIED MATERIALS & INTERFACES
2020
Targeted nanoparticles towards increased L cell stimulation as a strategy to improve oral peptide delivery in incretin-based diabetes treatment
Yining Xu
Herlinde De Keersmaecker
Kevin Braeckmans
Stefaan De Smedt
Patrice D. Cani
Véronique Préat
Ana Beloqui
A1
Journal Article
in
BIOMATERIALS
2020
The versatility of nucleic acids : a detailed view on mRNA therapeutics and the exploration of oligonucleotides for in-drug labeling
Heyang Zhang
Katrien Remaut
Stefaan De Smedt
Dissertation
2020
Vapor nanobubble is the more reliable photothermal mechanism for inducing endosomal escape of siRNA without disturbing cell homeostasis
Juan Fraire
Gaëlle Houthaeve
Jing Liu
Laurens Raes
Lotte Vermeulen
Stephan Stremersch
Toon Brans
Gerardo Garcia-Diaz Barriga
Sarah De Keulenaer
Filip Van Nieuwerburgh
Riet De Rycke
Jo Vandesompele
Pieter Mestdagh
Koen Raemdonck
Winnok H. De Vos
Stefaan De Smedt
Kevin Braeckmans
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2020
2019
Aerosolization of nanotherapeutics as a newly emerging treatment regimen for peritoneal carcinomatosis
Molood Shariati
Wouter Willaert
Wim Ceelen
Stefaan De Smedt
Katrien Remaut
A1
Journal Article
in
CANCERS
2019
Biocompatible lipid‐coated persistent luminescent nanoparticles for in vivo imaging of dendritic cell migration
Aranit Harizaj
Olivier De Clercq
Benedicte Descamps
Christian Vanhove
Stefaan De Smedt
Dirk Poelman
Ine Lentacker
Kevin Braeckmans
A1
Journal Article
in
PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION
2019
Broadening the message : a nanovaccine co-loaded with messenger RNA and α-GalCer induces antitumor immunity through conventional and natural killer T cells
Rein Verbeke
Ine Lentacker
Karine Breckpot
Jonas Janssens
Serge Van Calenbergh
Stefaan De Smedt
Heleen Dewitte
A1
Journal Article
in
ACS NANO
2019
Challenges for labeling and longitudinal tracking of adoptively transferred autoreactive T lymphocytes in an experimental type-1 diabetes model
Shweta Saini
Hannelie Korf
Sayuan Liang
Rein Verbeke
Bella Manshian
Koen Raemdonck
Ine Lentacker
Conny Gysemans
Stefaan De Smedt
Uwe Himmelreich
A1
Journal Article
in
MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE
2019
Comparison of MRI properties between multimeric DOTAGA and DO3A gadolinium-dendron conjugates
Maleotane Ndiaye
Volodymyr Malytskyi
Thomas Vangijzegem
Félix Sauvage
Mike Wels
Cyril Cadiou
Juliette Moreau
Céline Henoumont
Sébastien Boutry
Robert N. Muller
Dominique Harakat
Stefaan De Smedt
Sophie Laurent
Françoise Chuburu
A1
Journal Article
in
INORGANIC CHEMISTRY
2019
Design of messenger RNA lipid nanoparticles for cancer immunotherapy
Rein Verbeke
Stefaan De Smedt
Heleen Dewitte
Dissertation
2019
Ecofriendly electrospun membranes loaded with visible-light-responding nanoparticles for multifunctional usages : highly efficient air filtration, dye scavenging, and bactericidal activity
Dan Lv
Ruoxue Wang
Guosheng Tang
Zhipeng Mou
Jiandu Lei
Jingquan Han
Stefaan De Smedt
Ranhua Xiong
Chaobo Huang
A1
Journal Article
in
ACS APPLIED MATERIALS & INTERFACES
2019
Enhancing nucleic acid delivery with ultrasound and microbubbles
Heleen Dewitte
Silke Roovers
Stefaan De Smedt
Ine Lentacker
Bookchapter
in
Nanotechnology for nucleic acid delivery : methods and protocols
2019
Exploring light-sensitive nanocarriers for simultaneous triggered antibiotic release and disruption of biofilms upon generation of laser-induced vapor nanobubbles
Eline Teirlinck
Alexandre Barras
Jing Liu
Juan Fraire
Tatu Lajunen
Ranhua Xiong
Katrien Forier
Chengnan Li
Arto Urtti
Rabah Boukherroub
Sabine Szunerits
Stefaan De Smedt
Tom Coenye
Kevin Braeckmans
A1
Journal Article
in
PHARMACEUTICS
2019
Gas‐shearing fabrication of multicompartmental microspheres : a one‐step and oil‐free approach
Guosheng Tang
Ranhua Xiong
Dan Lv
Ronald X. Xu
Kevin Braeckmans
Chaobo Huang
Stefaan De Smedt
A1
Journal Article
in
ADVANCED SCIENCE
2019
Gold nanoparticle-mediated photoporation enables delivery of macromolecules over a wide range of molecular weights in human CD4+ T cells
Laurens Raes
Clarissa Van Hecke
Julie Michiels
Stephan Stremersch
Juan Fraire
Toon Brans
Ranhua Xiong
Stefaan De Smedt
Linos Vandekerckhove
Koen Raemdonck
Kevin Braeckmans
A1
Journal Article
in
CRYSTALS
2019
High pressure nebulization (PIPAC) versus injection for the intraperitoneal administration of mRNA complexes
Molood Shariati
Heyang Zhang
Leen Van de Sande
Benedicte Descamps
Christian Vanhove
Wouter Willaert
Wim Ceelen
Stefaan De Smedt
Katrien Remaut
A1
Journal Article
in
PHARMACEUTICAL RESEARCH
2019
Improved label-free identification of individual exosome-like vesicles with Au@Ag nanoparticles as SERS substrate
Juan Fraire
Stephan Stremersch
Davinia Bouckaert
Tinne Monteyne
Thomas De Beer
Pieter Wuytens
Riet De Rycke
Andre Skirtach
Koen Raemdonck
Stefaan De Smedt
Kevin Braeckmans
A1
Journal Article
in
ACS APPLIED MATERIALS & INTERFACES
2019
Laser-induced vapor nanobubbles improve diffusion in biofilms of antimicrobial agents for wound care
Eline Teirlinck
Juan Fraire
Heleen Van Acker
Jasper Wille
Rosalie Swimberghe
Toon Brans
Ranhua Xiong
Maarten Meire
Roeland De Moor
Stefaan De Smedt
Tom Coenye
Kevin Braeckmans
A2
Journal Article
in
BIOFILM
2019
Longitudinal in vivo assessment of host-microbe interactions in a murine model of pulmonary aspergillosis
Shweta Saini
Jennifer Poelmans
Hannelie Korf
James L. Dooley
Sayuan Liang
Bella B. Manshian
Rein Verbeke
Stefaan J. Soenen
Greetje Vande Velde
Ine Lentacker
Katrien Lagrou
Adrian Liston
Conny Gysemans
Stefaan De Smedt
Uwe Himmelreich
A1
Journal Article
in
ISCIENCE
2019
Morphology and composition of the inner limiting membrane : species-specific variations and relevance toward drug delivery research
Karen Peynshaert
Joke Devoldere
An-Katrien Minnaert
Stefaan De Smedt
Katrien Remaut
A1
Journal Article
in
CURRENT EYE RESEARCH
2019
Müller cells as a target for retinal therapy
Joke Devoldere
Karen Peynshaert
Stefaan De Smedt
Katrien Remaut
A1
Journal Article
in
DRUG DISCOVERY TODAY
2019
Nanocarrier lipid composition modulates the impact of pulmonary surfactant protein B (SP-B) on cellular delivery of siRNA
Roberta Guagliardo
Pieterjan Merckx
Agata Zamborlin
Lynn De Backer
Mercedes Echaide
Jesus Pérez-Gil
Stefaan De Smedt
Koen Raemdonck
A1
Journal Article
in
PHARMACEUTICS
2019
Non-viral delivery of chemically modified mRNA to the retina : subretinal versus intravitreal administration
Joke Devoldere
Karen Peynshaert
Heleen Dewitte
Christian Vanhove
Lies De Groef
Lieve Moons
Sinem Yilmaz Özcan
Deniz Dalkara
Stefaan De Smedt
Katrien Remaut
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2019
Photoablation of human vitreous opacities by light-induced vapor nanobubbles
Félix Sauvage
Juan Fraire
Katrien Remaut
J Sebag
Karen Peynshaert
Michael Harrington
Frans J Van de Velde
Ranhua Xiong
Marie-Jose Tassignon
Toon Brans
Kevin Braeckmans
Stefaan De Smedt
A1
Journal Article
in
ACS NANO
2019
Potential and pitfalls of non-viral mRNA delivery for ocular therapies
Joke Devoldere
Katrien Remaut
Stefaan De Smedt
Dissertation
2019
Sonoprinting liposomes on tumor spheroids by microbubbles and ultrasound
Silke Roovers
Joke Deprez
D Priwitaningrum
G Lajoinie
N Rivron
Heidi Declercq
Olivier De Wever
E Stride
S Le Gac
M Versluis
J Prakash
Stefaan De Smedt
Ine Lentacker
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2019
Sonoprinting of nanomedicines : from mechanistic insights to preclinical translation
Silke Roovers
Stefaan De Smedt
Ine Lentacker
Dissertation
2019
Sonoprinting of nanoparticle-loaded microbubbles : unraveling the multi-timescale mechanism
Silke Roovers
Guillaume Lajoinie
Ine De Cock
Toon Brans
Heleen Dewitte
Kevin Braeckmans
Michel Versuis
Stefaan De Smedt
Ine Lentacker
A1
Journal Article
in
BIOMATERIALS
2019
The obstacle course to the inner retina : hyaluronic acid-coated lipoplexes cross the vitreous but fail to overcome the inner limiting membrane
Joke Devoldere
Mike Wels
Karen Peynshaert
Heleen Dewitte
Stefaan De Smedt
Katrien Remaut
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
2019
The role of ultrasound-driven microbubble dynamics in drug delivery : from microbubble fundamentals to clinical translation
Silke Roovers
Tim Segers
Guillaume Lajoinie
Joke Deprez
Michel Versluis
Stefaan De Smedt
Ine Lentacker
A1
Journal Article
in
LANGMUIR
2019
Three decades of messenger RNA vaccine development
Rein Verbeke
Ine Lentacker
Stefaan De Smedt
Heleen Dewitte
A1
Journal Article
in
NANO TODAY
2019
2018
Endosomal size and membrane leakiness influence proton sponge-based rupture of endosomal vesicles
Lotte Vermeulen
Toon Brans
Sangram Keshari Samal
Peter Dubruel
Jo Demeester
Stefaan De Smedt
Katrien Remaut
Kevin Braeckmans
A1
Journal Article
in
ACS NANO
2018
Fluorescence correlation spectroscopy to find the critical balance between extracellular association and intracellular dissociation of mRNA complexes
Heyang Zhang
Stefaan De Smedt
Katrien Remaut
A1
Journal Article
in
ACTA BIOMATERIALIA
2018
In vitro and ex vivo models to study drug delivery barriers in the posterior segment of the eye
Karen Peynshaert
Joke Devoldere
Stefaan De Smedt
Katrien Remaut
A1
Journal Article
in
ADVANCED DRUG DELIVERY REVIEWS
2018
Laser-induced vapour nanobubbles improve drug diffusion and efficiency in bacterial biofilms
Eline Teirlinck
Ranhua Xiong
Toon Brans
Katrien Forier
Juan Fraire
Heleen Van Acker
Nele Matthijs
Riet De Rycke
Stefaan De Smedt
Tom Coenye
Kevin Braeckmans
A1
Journal Article
in
NATURE COMMUNICATIONS
2018
Methodologies to investigate intracellular barriers for nucleic acid delivery in non-viral gene therapy
Lotte Vermeulen
Toon Brans
Stefaan De Smedt
Katrien Remaut
Kevin Braeckmans
A1
Journal Article
in
NANO TODAY
2018
Nanomaterials and molecular transporters to overcome the bacterial envelope barrier : towards advanced delivery of antibiotics
Rita Santos
Céu Figueiredo
Nuno F Azevedo
Kevin Braeckmans
Stefaan De Smedt
A1
Journal Article
in
ADVANCED DRUG DELIVERY REVIEWS
2018
Nucleic acid loading and fluorescent labeling of isolated extracellular vesicles requires adequate purification
Stephan Stremersch
Toon Brans
Kevin Braeckmans
Stefaan De Smedt
Koen Raemdonck
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2018
Optimized messenger RNA immunolipoplexes for cancer immunotherapy : balancing immunogenicity and adjuvancy
Rein Verbeke
Ine Lentacker
Karine Breckpot
Serge Van Calenbergh
Stefaan De Smedt
Heleen Dewitte
C3
Conference
2018
Photothermally triggered endosomal escape and its influence on transfection efficiency of gold-functionalized JetPEI/pDNA nanoparticles
Lotte Vermeulen
Juan Fraire
Laurens Raes
Ellen De Meester
Sarah De Keulenaer
Filip Van Nieuwerburgh
Stefaan De Smedt
Katrien Remaut
Kevin Braeckmans
A1
Journal Article
in
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2018
Pulmonary surfactant and drug delivery : focusing on the role of surfactant proteins
Roberta Guagliardo
Jésus Pérez-Gil
Stefaan De Smedt
Koen Raemdonck
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2018
Quantifying the average number of nucleic acid therapeutics per nanocarrier by single particle tracking microscopy
Elisa Zagato
Lotte Vermeulen
Heleen Dewitte
Griet Van Imschoot
Roosmarijn Vandenbroucke
Jo Demeester
Stefaan De Smedt
Kristiaan Neyts
Katrien Remaut
Kevin Braeckmans
A1
Journal Article
in
MOLECULAR PHARMACEUTICS
2018
Repeated photoporation with graphene quantum dots enables homogeneous labeling of live cells with extrinsic markers for fluorescence microscopy
Jing Liu
Ranhua Xiong
Toon Brans
Saskia Lippens
Eef Parthoens
Francesca Cella Zanacchi
Raffaella Magrassi
Santosh K Singh
Sreekumar Kurungot
Sabine Szunerits
Hannelore Bové
Marcel Ameloot
Juan Fraire
Eline Teirlinck
Sangram Keshari Samal
Riet De Rycke
Gaëlle Houthaeve
Stefaan De Smedt
Rabah Boukherroub
Kevin Braeckmans
A1
Journal Article
in
LIGHT-SCIENCE & APPLICATIONS
2018
Repurposing cationic amphiphilic drugs as adjuvants to induce lysosomal siRNA escape in nanogel transfected cells
Freya Joris
Lynn De Backer
Thijs Van de Vyver
Chiara Bastiancich
Stefaan De Smedt
Koen Raemdonck
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2018
Selective labeling of individual neurons in dense cultured networks with nanoparticle-enhanced photoporation
Ranhua Xiong
Peter Verstraelen
Jo Demeester
Andre Skirtach
Jean-Pierre Timmermans
Stefaan De Smedt
Winnok De Vos
Kevin Braeckmans
A1
Journal Article
in
FRONTIERS IN CELLULAR NEUROSCIENCE
2018
Surfactant protein B (SP-B) enhances the cellular siRNA delivery of proteolipid coated nanogels for inhalation therapy
Pieterjan Merckx
Lynn De Backer
Lien Van Hoecke
Roberta Guagliardo
Mercedes Echaide
Pieter Baatsen
Bárbara Olmeda
Xavier Saelens
Jésus Pérez-Gil
Stefaan De Smedt
Koen Raemdonck
A1
Journal Article
in
ACTA BIOMATERIALIA
2018
Targeted perturbation of nuclear envelope integrity with vapor nanobubble-mediated photoporation
Gaëlle Houthaeve
Ranhua Xiong
Joke Robijns
Bert Luyckx
Yasmine Beulque
Toon Brans
Coen Campsteijn
Sangram Keshari Samal
Stephan Stremersch
Stefaan De Smedt
Kevin Braeckmans
Winnok De Vos
A1
Journal Article
in
ACS NANO
2018
Technical implementations of light sheet microscopy
Elisa Zagato
Toon Brans
Stefaan De Smedt
Katrien Remaut
Kristiaan Neyts
Kevin Braeckmans
A1
Journal Article
in
MICROSCOPY RESEARCH AND TECHNIQUE
2018
The proton sponge hypothesis : fable or fact?
Lotte Vermeulen
Stefaan De Smedt
Katrien Remaut
Kevin Braeckmans
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
2018
What you see is what you get : the physicochemistry of nanoparticles dictates how they cross ocular delivery barriers and alter autophagy
Karen Peynshaert
Katrien Remaut
Stefaan De Smedt
Dissertation
2018
2017
Co-delivery of nucleoside-modified mRNA and TLR agonists for cancer immunotherapy : restoring the immunogenicity of immunosilent mRNA
Rein Verbeke
Ine Lentacker
Laura Wayteck
Karine Breckpot
Mieke Van Bockstal
Benedicte Descamps
Christian Vanhove
Stefaan De Smedt
Heleen Dewitte
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2017
Co-delivery of nucleoside-modified mRNA and immunomodulators for cancer immunotherapy: restoring the immunogenicity of immunosilent mRNA
Rein Verbeke
Ine Lentacker
Laura Wayteck
Karine Breckpot
Benedicte Descamps
Christian Vanhove
Stefaan De Smedt
Heleen Dewitte
C3
Conference
2017
Coating of quantum dots strongly defines their effect on lysosomal health and autophagy
Karen Peynshaert
Stefaan J Soenen
Bella B Manshian
Shareen H Doak
Kevin Braeckmans
Stefaan De Smedt
Katrien Remaut
A1
Journal Article
in
ACTA BIOMATERIALIA
2017
Comparing photoporation and nucleofection for delivery of small interfering RNA to cytotoxic T cells
Laura Wayteck
Ranhua Xiong
Kevin Braeckmans
Stefaan De Smedt
Koen Raemdonck
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2017
Effect of hyaluronic acid-binding to lipoplexes on intravitreal drug delivery for retinal gene therapy
Thomas Martens
Karen Peynshaert
Thaís Leite Nascimento
Elias Fattal
Marcus Karlstetter
Thomas Langmann
Serge Picaud
Jo Demeester
Stefaan De Smedt
Katrien Remaut
Kevin Braeckmans
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
2017
Exploring the HYDRAtion method for loading siRNA on liposomes : the interplay between stability and biological activity in human undiluted ascites fluid
George Dakwar
Kevin Braeckmans
Wim Ceelen
Stefaan De Smedt
Katrien Remaut
A1
Journal Article
in
DRUG DELIVERY AND TRANSLATIONAL RESEARCH
2017
Fast spatial-selective delivery into live cells
Ranhua Xiong
Claire Drullion
Peter Verstraelen
Jo Demeester
Andre Skirtach
Corinne Abbadie
Winnok De Vos
Stefaan De Smedt
Kevin Braeckmans
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2017
High-pressure nebulization as application route for the peritoneal administration of siRNA complexes
An-Katrien Minnaert
George Dakwar
Juan M Benito
José M García Fernández
Wim Ceelen
Stefaan De Smedt
Katrien Remaut
A1
Journal Article
in
MACROMOLECULAR BIOSCIENCE
2017
In vitro and ex vivo delivery of tailored siRNA-nanoliposomes for E2F1 silencing as a potential therapy for colorectal cancer
Sabrina Bochicchio
Barbara Dapas
Ilaria Russo
Carolina Ciacci
Ornella Piazza
Stefaan De Smedt
Eline Pottie
Anna Angela Barba
Gabriele Grassi
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2017
Intracellular delivery of biopharmaceuticals and contrast agents by VNB photoporation and sizing nanomaterials in bio-fluids by FRAP
Ranhua Xiong
Kevin Braeckmans
Stefaan De Smedt
Andre Skirtach
Dissertation
2017
Intracellular delivery of oligonucleotides in Helicobacter pylori by fusogenic liposomes in the presence of gastric mucus
Rita Santos
George Dakwar
Elisa Zagato
Toon Brans
Céu Figueiredo
Koen Raemdonck
Nuno F Azevedo
Stefaan De Smedt
Kevin Braeckmans
A1
Journal Article
in
BIOMATERIALS
2017
Microfabricated devices for single objective single plane illumination microscopy (SoSPIM)
Elisa Zagato
Toon Brans
Steven Verstuyft
Dries Van Thourhout
Jeroen Missinne
Geert Van Steenberge
Jo Demeester
Stefaan De Smedt
Katrien Remaut
Kristiaan Neyts
Kevin Braeckmans
A1
Journal Article
in
OPTICS EXPRESS
2017
Nanomedicine-based intraperitoneal therapy for the treatment of peritoneal carcinomatosis : mission possible?
George Dakwar
Molood Shariati
Wouter Willaert
Wim Ceelen
Stefaan De Smedt
Katrien Remaut
A1
Journal Article
in
ADVANCED DRUG DELIVERY REVIEWS
2017
PEGylated and functionalized aliphatic polycarbonate polyplex nanoparticles for intravenous administration of HDAC5 siRNA in cancer therapy
Antoine Frère
Alexandra Baroni
Elodie Hendrick
Anne-Sophie Delvigne
François Orange
Olivier Peulen
George Dakwar
Jérôme Diricq
Philippe Dubois
Brigitte Evrard
Katrien Remaut
Kevin Braeckmans
Stefaan De Smedt
Julie Laloy
Jean-Michel Dogné
Georges Feller
Laetitia Mespouille
Denis Mottet
Géraldine Piel
A1
Journal Article
in
ACS APPLIED MATERIALS & INTERFACES
2017
Polyimide/cellulose acetate core/shell electrospun fibrous membranes for oil-water separation
Wenjing Ma
Zhongfu Guo
Juntao Zhao
Qian Yu
Fang Wang
Jingquan Han
Hui Pan
Jianfeng Yao
Qilu Zhang
Sangram Keshari Samal
Stefaan De Smedt
Chaobo Huang
A1
Journal Article
in
SEPARATION AND PURIFICATION TECHNOLOGY
2017
The repurposing of low molecular weight drugs to induce lysosomal release of siRNA and in vitro approaches to probe the toxicity of inorganic nanoparticles
Freya Joris
Stefaan De Smedt
Koen Raemdonck
Dissertation
2017
The role of intracellular trafficking of CdSe/ZnS QDs on their consequent toxicity profile
Bella B Manshian
Thomas Martens
Karsten Kantner
Kevin Braeckmans
Stefaan De Smedt
Jo Demeester
Gareth JS Jenkins
Wolfgang J Parak
Beatriz Pelaz
Shareen H Doak
Uwe Himmelreich
Stefaan J Soenen
A1
Journal Article
in
JOURNAL OF NANOBIOTECHNOLOGY
2017
Toward smart design of retinal drug carriers : a novel bovine retinal explant model to study the barrier role of the vitreoretinal interface
Karen Peynshaert
Joke Devoldere
Valérie Forster
Serge Picaud
Christian Vanhove
Stefaan De Smedt
Katrien Remaut
A1
Journal Article
in
DRUG DELIVERY
2017
Unraveling the potential of nucleic acid mimics to target Helicobacter pylori infections : the effect of biological barriers
Rita Sobral Fernandes Machado dos Santos
Nuno F Azevedo
Kevin Braeckmans
Stefaan De Smedt
Céu Figueiredo
Dissertation
2017
mRNA-based nanoparticles for therapeutic cancer vaccination
Rein Verbeke
Laura Wayteck
Karine Breckpot
Christian Vanhove
Benedicte Descamps
Stefaan De Smedt
Heleen Dewitte
Ine Lentacker
C3
Conference
2017
2016
Combining the strengths of cytotoxic T cells and nanomedicines for cancer immunotherapy
Laura Wayteck
Stefaan De Smedt
Koen Raemdonck
Dissertation
2016
Comparing exosome-like vesicles with liposomes for the functional cellular delivery of small RNAs
Stephan Stremersch
Roosmarijn Vandenbroucke
Elien Van Wonterghem
An Hendrix
Stefaan De Smedt
Koen Raemdonck
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2016
Core-sheath structured electrospun nanofibrous membranes for oil-water separation
Wenjing Ma
Qilu Zhang
Sangram Keshari Samal
Fang Wang
Buhong Gao
Hui Pan
Haijun Xu
Jianfeng Yao
Xianxu Zhan
Stefaan De Smedt
Chaobo Huang
A1
Journal Article
in
RSC ADVANCES
2016
Cytosolic delivery of nanolabels prevents their asymmetric inheritance and enables extended quantitative in vivo cell imaging
Ranhua Xiong
Freya Joris
Sayuan Liang
Riet De Rycke
Saskia Lippens
Jo Demeester
Andre Skirtach
Koen Raemdonck
Uwe Himmelreich
Stefaan De Smedt
Kevin Braeckmans
A1
Journal Article
in
NANO LETTERS
2016
Evading innate immunity in nonviral mRNA delivery : don't shoot the messenger
Joke Devoldere
Heleen Dewitte
Stefaan De Smedt
Katrien Remaut
A1
Journal Article
in
DRUG DISCOVERY TODAY
2016
Exploring extracellular vesicles for siRNA delivery and Raman-based diagnostics
Stephan Stremersch
Stefaan De Smedt
Koen Raemdonck
Kevin Braeckmans
Dissertation
2016
Exploring the intraperitoneal route of administration for siRNA delivery in the treatment of pertitoneal carcinomatosis
George Dakwar
Katrien Remaut
Stefaan De Smedt
Wim Ceelen
Dissertation
2016
Hitchhiking nanoparticles: reversible coupling of lipid-based nanoparticles to cytotoxic T lymphocytes
Laura Wayteck
Heleen Dewitte
Lynn De Backer
Karine Breckpot
Jo Demeester
Stefaan De Smedt
Koen Raemdonck
A1
Journal Article
in
BIOMATERIALS
2016
Identification of individual exosome-like vesicles by surface enhanced Raman spectroscopy
Stephan Stremersch
Monica Marro
Bat-El Pinchasik
Pieter Baatsen
An Hendrix
Stefaan De Smedt
Pablo Loza-Alvarez
Andre Skirtach
Koen Raemdonck
Kevin Braeckmans
A1
Journal Article
in
SMALL
2016
Laser-assisted photoporation : fundamentals, technological advances and applications
Ranhua Xiong
Sangram Keshari Samal
Jo Demeester
Andre Skirtach
Stefaan De Smedt
Kevin Braeckmans
A1
Journal Article
in
ADVANCES IN PHYSICS-X
2016
Sizing nanomaterials in bio-fluids by cFRAP enables protein aggregation measurements and diagnosis of bio-barrier permeability
Ranhua Xiong
Roosmarijn Vandenbroucke
Katleen Broos
Toon Brans
Elien Van Wonterghem
Claude Libert
Jo Demeester
Stefaan De Smedt
Kevin Braeckmans
A1
Journal Article
in
NATURE COMMUNICATIONS
2016
Sonoprinting and the importance of microbubble loading for the ultrasound mediated cellular delivery of nanoparticles
Ine De Cock
Guillaume Lajoinie
Michel Versluis
Stefaan De Smedt
Ine Lentacker
A1
Journal Article
in
BIOMATERIALS
2016
The impact of species and cell type on the nanosafety profile of iron oxide nanoparticles in neural cells
Freya Joris
Daniel Valdepérez
Beatriz Pelaz
Stefaan J Soenen
Bella B Manshian
Wolfgang J Parak
Stefaan De Smedt
Koen Raemdonck
A1
Journal Article
in
JOURNAL OF NANOBIOTECHNOLOGY
2016
Therapeutic and diagnostic applications of extracellular vesicles
Stephan Stremersch
Stefaan De Smedt
Koen Raemdonck
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2016
Unraveling microbubble-cell interactions and drug delivery mechanisms in ultrasound-guided therapy
Ine De Cock
Stefaan De Smedt
Ine Lentacker
Dissertation
2016
pH responsive polyurethane (core) and cellulose acetate phthalate (shell) electrospun fibers for intravaginal drug delivery
Dawei Hua
Zhongche Liu
Fang Wang
Buhong Gao
Fei Chen
Qilu Zhang
Ranhua Xiong
Jingquan Han
Sangram Keshari Samal
Stefaan De Smedt
Chaobo Huang
A1
Journal Article
in
CARBOHYDRATE POLYMERS
2016
2015
Bio-inspired materials in drug delivery : exploring the role of pulmonary surfactant in siRNA inhalation therapy
Lynn De Backer
Alejandro Cerrada
Jesús Pérez-Gil
Stefaan De Smedt
Koen Raemdonck
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2015
Bio-inspired pulmonary surfactant-modified nanogels : a promising siRNA delivery system
Lynn De Backer
Kevin Braeckmans
Marc CA Stuart
Jo Demeester
Stefaan De Smedt
Koen Raemdonck
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2015
Biomimetic magnetic silk scaffolds
Sangram Keshari Samal
Mamoni Dash
Tatiana Shelyakova
Heidi Declercq
Marc Uhlarz
Manuel Banobre-Lopez
Peter Dubruel
Maria Cornelissen
Thomas Herrmannsdorfer
Jose Rivas
Giuseppina Padeletti
Stefaan De Smedt
Kevin Braeckmans
David L Kaplan
V Alek Dediu
A1
Journal Article
in
ACS APPLIED MATERIALS & INTERFACES
2015
Coating nanocarriers with hyaluronic acid facilitates intravitreal drug delivery for retinal gene therapy
Thomas Martens
Katrien Remaut
Hendrik Deschout
Johan FJ Engbersen
Wim E Hennink
Mies J van Steenbergen
Jo Demeester
Stefaan De Smedt
Kevin Braeckmans
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2015
Design and evaluation of immunotherapeutic imaging for cancer vaccination
Heleen Dewitte
Stefaan De Smedt
Karine Breckpot
Ine Lentacker
Dissertation
2015
Disregarded effect of biological fluids in siRNA delivery : human ascites fluid severely restricts cellular uptake of nanoparticles
George Dakwar
Kevin Braeckmans
Jo Demeester
Wim Ceelen
Stefaan De Smedt
Katrien Remaut
A1
Journal Article
in
ACS APPLIED MATERIALS & INTERFACES
2015
Effect of native gastric mucus on in vivo hybridization therapies directed at Helicobacter pylori
Rita Santos
George Dakwar
Ranhua Xiong
Katrien Forier
Katrien Remaut
Stephan Stremersch
Nuno Guimarães
Silvia Fontenete
Jesper Wengel
Marina Leite
Céu Figueiredo
Stefaan De Smedt
Kevin Braeckmans
Nuno F Azevedo
A1
Journal Article
in
MOLECULAR THERAPY-NUCLEIC ACIDS
2015
Efficient delivery of quantum dots in live cells by gold nanoparticle mediated photoporation
Ranhua Xiong
Freya Joris
Ine De Cock
Jo Demeester
Stefaan De Smedt
Andre Skirtach
Kevin Braeckmans
P1
Conference
2015
Evaluation of mRNA lipoplexes for single-step antigen loading and maturation of dendritic cells in cancer immunotherapy
Rein Verbeke
Heleen Dewitte
Ine Lentacker
Stefaan De Smedt
C3
Conference
2015
Exploring bio-inspired nanocomposites of nanogels and pulmonary surfactant for small interfering RNA delivery
Lynn De Backer
Stefaan De Smedt
Koen Raemdonck
Dissertation
2015
Hybrid pulmonary surfactant-coated nanogels mediate efficient in vivo delivery of siRNA to murine alveolar macrophages
Lynn De Backer
Thomas Naessens
Stefaan De Koker
Elisa Zagato
Jo Demeester
Johan Grooten
Stefaan De Smedt
Koen Raemdonck
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2015
Immunogenic mRNA nanoparticles for dendritic cell-based cancer vaccination
Rein Verbeke
Heleen Dewitte
Ine Lentacker
Stefaan De Smedt
C3
Conference
2015
Intraperitoneal nonviral nucleic acid delivery in the treatment of peritoneal cancer
George Dakwar
Stefaan De Smedt
Katrien Remaut
Bookchapter
in
Intraperitoneal cancer therapy : principles and practice
2015
Laser-induced vapor nanobubbles for efficient delivery of macromolecules in live cells
Ranhua Xiong
Koen Raemdonck
Karen Peynshaert
Ine Lentacker
Ine De Cock
Jo Demeester
Stefaan De Smedt
Andre Skirtach
Kevin Braeckmans
P1
Conference
2015
Lessons in simplicity that should shape the future of drug delivery
Koen Raemdonck
Stefaan De Smedt
A1
Journal Article
in
NATURE BIOTECHNOLOGY
2015
Microbubbles as magic bullets in cancer immunotherapy
Heleen Dewitte
Sandra Van Lint
Katrien Vanderperren
Hendrik Haers
Emmelie Stock
Stefaan De Smedt
Karine Breckpot
Ine Lentacker
C3
Conference
2015
Multilayered magnetic gelatin membrane scaffolds
Sangram Keshari Samal
Vitaly Goranov
Mamoni Dash
Alessandro Russo
Tatiana Shelyakova
Patrizio Graziosi
Lisa Lungaro
Alberto Riminucci
Marc Uhlarz
Manuel Banobre-Lopez
Jose Rivas
Thomas Herrmannsdorfer
Jayakumar Rajadas
Stefaan De Smedt
Kevin Braeckmans
David L Kaplan
V Alek Dediu
A1
Journal Article
in
ACS APPLIED MATERIALS & INTERFACES
2015
N-1-methylpseudouridine-incorporated mRNA outperforms pseudouridine-incorporated mRNA by providing enhanced protein expression and reduced immunogenicity in mammalian cell lines and mice
Oliwia Andries
Séan Mc Cafferty
Stefaan De Smedt
Ron Weiss
Niek Sanders
Tasuku Kitada
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2015
The effect of intracellular degradation on cytotoxicity and cell labeling efficacy of inorganic ligand-stabilized colloidal CdSe/CdS quantum dots
Stefaan Soenen
Sofie Abé
Bella B Manshian
Tangi Aubert
Zeger Hens
Stefaan De Smedt
Kevin Braeckmans
A1
Journal Article
in
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
2015
Theranostic mRNA-loaded microbubbles in the lymphatics of dogs: implications for drug delivery
Heleen Dewitte
Katrien Vanderperren
Hendrik Haers
Emmelie Stock
Luc Duchateau
Myriam Hesta
Jimmy Saunders
Stefaan De Smedt
Ine Lentacker
A1
Journal Article
in
THERANOSTICS
2015
Transport mechanisms of squalenoyl-adenosine nanoparticles across the blood-brain barrier
Alice Gaudin
Oya Tagit
Dunja Sobot
Sinda Lepetre-Mouelhi
Julie Mougin
Thomas F Martens
Kevin Braeckmans
Valerie Nicolas
Didier Desmaele
Stefaan De Smedt
Niko Hildebrandt
Patrick Couvreur
Karine Andrieux
A1
Journal Article
in
CHEMISTRY OF MATERIALS
2015
Ultrasound and microbubble mediated drug delivery: acoustic pressure as determinant for uptake via membrane pores or endocytosis
Ine De Cock
Elisa Zagato
Kevin Braeckmans
Ying Luan
Nico de Jong
Stefaan De Smedt
Ine Lentacker
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2015
mRNA Modification and delivery strategies towards the establishment of a platform for safe and effective gene therapy
Oliwia Andries
Niek Sanders
Stefaan De Smedt
Tasuku Kitada
Dissertation
2015
2014
A personalized view on cancer immunotherapy
Laura Wayteck
Karine Breckpot
Jo Demeester
Stefaan De Smedt
Koen Raemdonck
A1
Journal Article
in
CANCER LETTERS
2014
Cell division responsive peptides for optimized plasmid DNA delivery : the mitotic window of opportunity?
Katrien Remaut
Nathalie Symens
Bart Lucas
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2014
Chitosan nanoparticles for siRNA delivery : optimizing formulation to increase stability and efficiency
H Ragelle
R Riva
G Vandermeulen
Broes Naeye
V Pourcelle
CS Le Duff
C D'Haese
B Nysten
Kevin Braeckmans
Stefaan De Smedt
C Jerome
V Preat
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2014
Choose your models wisely: how different murine bone marrow-derived dendritic cell protocols influence the success of nanoparticulate vaccines in vitro
Heleen Dewitte
Rein Verbeke
Karine Breckpot
Roosmarijn Vandenbroucke
Claude Libert
Stefaan De Smedt
Ine Lentacker
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2014
Colloidal stability of nano-sized particles in the peritoneal fluid : towards optimizing drug delivery systems for intraperitoneal therapy
George Dakwar
Elisa Zagato
Joris Delanghe
Sabina Hobel
Achim Aigner
Hannelore Denys
Kevin Braeckmans
Wim Ceelen
Stefaan De Smedt
Katrien Remaut
A1
Journal Article
in
ACTA BIOMATERIALIA
2014
Comparison of gold nanoparticle mediated photoporation: vapor nanobubbles outperform direct heating for delivering macromolecules in live cells
Ranhua Xiong
Koen Raemdonck
Karen Peynshaert
Ine Lentacker
Ine De Cock
Jo Demeester
Stefaan De Smedt
Andre Skirtach
Kevin Braeckmans
A1
Journal Article
in
ACS NANO
2014
Cytotoxicity of cadmium-free quantum dots and their use in cell bioimaging
Stefaan Soenen
Bella B Manshian
Tangi Aubert
Uwe Himmelreich
Jo Demeester
Stefaan De Smedt
Zeger Hens
Kevin Braeckmans
A1
Journal Article
in
CHEMICAL RESEARCH IN TOXICOLOGY
2014
Effect of covalent fluorescence labeling of plasmid DNA on its intracellular processing and transfection with lipid-based carriers
Koen Rombouts
Thomas Martens
Elisa Zagato
Jo Demeester
Stefaan De Smedt
Kevin Braeckmans
Katrien Remaut
A1
Journal Article
in
MOLECULAR PHARMACEUTICS
2014
Electrospun polystyrene fibers for HIV entrapment
Chaobo Huang
Stefaan Soenen
Ellen van Gulck
Joanna Rejman
Guido Vanham
Bart Lucas
Bart Geers
Kevin Braeckmans
Victor Shahin
Pieter Spanoghe
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
POLYMERS FOR ADVANCED TECHNOLOGIES
2014
Exploiting intrinsic nanoparticle toxicity: the pros and cons of nanoparticle-induced autophagy in biomedical research
Karen Peynshaert
Bella Barjouhi Manshian
Freya Joris
Kevin Braeckmans
Stefaan De Smedt
Jo Demeester
Stefaan Soenen
A1
Journal Article
in
CHEMICAL REVIEWS
2014
FRAP in pharmaceutical research: practical guidelines and applications in drug delivery
Hendrik Deschout
Koen Raemdonck
Jo Demeester
Stefaan De Smedt
Kevin Braeckmans
A1
Journal Article
in
PHARMACEUTICAL RESEARCH
2014
Intracellular delivery of nanomaterials: how to catch endosomal escape in the act
Thomas Martens
Katrien Remaut
Jo Demeester
Stefaan De Smedt
Kevin Braeckmans
A1
Journal Article
in
NANO TODAY
2014
Lipid and polymer nanoparticles for drug delivery to bacterial biofilms
Katrien Forier
Koen Raemdonck
Stefaan De Smedt
Jo Demeester
Tom Coenye
Kevin Braeckmans
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2014
Lysosomal capturing of cytoplasmic injected nanoparticles by autophagy: an additional barrier to non viral gene delivery
Katrien Remaut
Viola Oorschot
Kevin Braeckmans
Judith Klumperman
Stefaan De Smedt
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2014
Magnetic layer-by-layer coated particles for efficient MRI of dendritic cells and mesenchymal stem cells
Marie-Luce De Temmerman
Stefaan Soenen
Nathalie Symens
Bart Lucas
Roosmarijn Vandenbroucke
Claude Libert
Jo Demeester
Stefaan De Smedt
Uwe Himmelreich
Joanna Rejman
A1
Journal Article
in
NANOMEDICINE
2014
Merging the best of both worlds : hybrid lipid-enveloped matrix nanocomposites in drug delivery
Koen Raemdonck
Kevin Braeckmans
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
CHEMICAL SOCIETY REVIEWS
2014
Nanoparticle design to induce tumor immunity and challenge the suppressive tumor microenvironment
Heleen Dewitte
Rein Verbeke
Karine Breckpot
Stefaan De Smedt
Ine Lentacker
A1
Journal Article
in
NANO TODAY
2014
On-chip light sheet illumination enables diagnostic size and concentration measurements of membrane vesicles in biofluids
Hendrik Deschout
Koen Raemdonck
Stephan Stremersch
Pietro Maoddi
Guillaume Mernier
Philippe Renaud
Sebastien Jiguet
An Hendrix
Marc Bracke
Rudy Van den Broecke
Magnus Röding
Mats Rudemo
Jo Demeester
Stefaan De Smedt
Filip Strubbe
Kristiaan Neyts
Kevin Braeckmans
A1
Journal Article
in
NANOSCALE
2014
Optimizing delivery of gene nanomedicines towards the retina via intravitreal administration
Thomas Martens
Kevin Braeckmans
Stefaan De Smedt
Katrien Remaut
Dissertation
2014
Probing the size limit for nanomedicine penetration into Burkholderia multivorans and Pseudomonas aeruginosa biofilms
Katrien Forier
Anne-Sophie Messiaen
Koen Raemdonck
Hans Nelis
Stefaan De Smedt
Jo Demeester
Tom Coenye
Kevin Braeckmans
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2014
Single-particle tracking for studying nanomaterial dynamics: applications and fundamentals in drug delivery
Elisa Zagato
Katrien Forier
Thomas Martens
Kristiaan Neyts
Jo Demeester
Stefaan De Smedt
Katrien Remaut
Kevin Braeckmans
A1
Journal Article
in
NANOMEDICINE
2014
The bubble breakthrough in cancer immunotherapy
Heleen Dewitte
Sandra Van Lint
Katrien Vanderperren
Stefaan De Smedt
Karine Breckpot
Ine Lentacker
C3
Conference
2014
The bubble breakthrough in cancer immunotherapy : Mma-sonoporation in dendritic cell-based cancer vaccination
Heleen Dewitte
Sandra Van Lint
Katrien Vanderperren
Kris Thielemans
Stefaan De Smedt
Karine Breckpot
Ine Lentacker
C3
Conference
2014
The bubble breakthrough in cancer immunotherapy : Mma-sonoporation in dendritic cell-based cancer vaccination
Heleen Dewitte
Sandra Van Lint
Katrien Vanderperren
Kris Thielemans
Stefaan De Smedt
Karine Breckpot
Ine Lentacker
C3
Conference
2014
The cellular interactions of PEGylated gold nanoparticles : effect of PEGylation on cellular uptake and cytotoxicity
Stefaan Soenen
Bella B Manshian
Abuelmagd M Abdelmonem
José-María Montenegro
Sisareuth Tan
Lieve Balcaen
Frank Vanhaecke
Alain R Brisson
Wolfgang J Parak
Stefaan De Smedt
Kevin Braeckmans
A1
Journal Article
in
PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION
2014
The effect of nanoparticle degradation on poly(methacrylic acid)-coated quantum dot toxicity : the importance of particle functionality assessment in toxicology
Stefaan Soenen
Jose-Maria Montenegro
Abuelmagd Abdelmonem
Bella Manshian
Shareen Doak
Wolfgang Parak
Stefaan De Smedt
Kevin Braeckmans
A1
Journal Article
in
ACTA BIOMATERIALIA
2014
The performance of gradient alloy quantum dots in cell labeling
Stefaan Soenen
Bella B Manshian
Uwe Himmelreich
Jo Demeester
Kevin Braeckmans
Stefaan De Smedt
A1
Journal Article
in
BIOMATERIALS
2014
The potential of antigen and TriMix sonoporation using mRNA-loaded microbubbles for ultrasound-triggered cancer immunotherapy
Heleen Dewitte
Sandra Van Lint
Carlo Heirman
Kris Thielemans
Stefaan De Smedt
Karine Breckpot
Ine Lentacker
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2014
Understanding ultrasound induced sonoporation: definitions and underlying mechanisms
Ine Lentacker
Ine De Cock
R Deckers
Stefaan De Smedt
CTW Moonen
A1
Journal Article
in
ADVANCED DRUG DELIVERY REVIEWS
2014
Unraveling the effects of siRNA carrier systems on cell physiology: a multiparametric approach demonstrated on dextran nanogels
Stefaan Soenen
Lynn De Backer
Bella Manshian
Shareen Doak
Koen Raemdonck
Jo Demeester
Kevin Braeckmans
Stefaan De Smedt
A1
Journal Article
in
NANOMEDICINE
2014
2013
Assessing nanoparticle toxicity in cell-based assays : influence of cell culture parameters and optimized models for bridging the in vitro-in vivo gap
Freya Joris
Bella B Manshian
Karen Peynshaert
Stefaan De Smedt
Kevin Braeckmans
Stefaan Soenen
A1
Journal Article
in
CHEMICAL SOCIETY REVIEWS
2013
Comparison of in vivo optical systems for bioluminescence and fluorescence imaging
Steven Cool
Koen Breyne
Evelyne Meyer
Stefaan De Smedt
Niek Sanders
A1
Journal Article
in
JOURNAL OF FLUORESCENCE
2013
Correlation of dual colour single particle trajectories for improved detection and analysis of interactions in living cells
Hendrik Deschout
Thomas Martens
Dries Vercauteren
Katrien Remaut
Jo Demeester
Stefaan De Smedt
Kristiaan Neyts
Kevin Braeckmans
A1
Journal Article
in
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2013
Coupling of drug containing liposomes to microbubbles improves ultrasound triggered drug delivery in mice
Steven Cool
Bart Geers
Stefan Roels
Stephan Stremersch
Katrien Vanderperren
Jimmy Saunders
Stefaan De Smedt
Jo Demeester
Niek Sanders
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2013
Current methods for inducing pluripotency in somatic cells
Geertrui Tavernier
Barbara Mlody
Jo Demeester
James Adjaye
Stefaan De Smedt
A1
Journal Article
in
ADVANCED MATERIALS
2013
Design and evaluation of theranostic perfluorocarbon particles for simultaneous antigen-loading and 19F-MRI tracking of dendritic cells
Heleen Dewitte
Bart Geers
Sayuan Liang
Uwe Himmelreich
Jo Demeester
Stefaan De Smedt
Ine Lentacker
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2013
Development of nanomedicines for the treatment of pulmonary biofilm infections: Insights from advanced fluorescence microscopy studies
Katrien Forier
Anne-Sophie Messiaen
Martijn Risseeuw
Serge Van Calenbergh
Hendrik Deschout
Koen Raemdonck
Hans Nelis
Fabienne Danhier
Véronique Préat
Frans De Baets
Stefaan De Smedt
Jo Demeester
Tom Coenye
Kevin Braeckmans
C3
Conference
2013
Electroporation-induced siRNA precipitation obscures the efficiency of siRNA loading into extracellular vesicles
Sander AA Kooijmans
Stephan Stremersch
Kevin Braeckmans
Stefaan De Smedt
An Hendrix
Matthew JA Wood
Raymond M Schiffelers
Koen Raemdonck
Pieter Vader
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2013
Enhancing nucleic acid delivery with ultrasound and microbubbles
Steven Cool
Bart Geers
Ine Lentacker
Stefaan De Smedt
Niek Sanders
Bookchapter
in
Nanotechnology for nucleic acid delivery : methods and protocols
2013
Fluorescent non-porous silica nanoparticles for long-term cell monitoring: cytotoxicity and particle functionality
Stefaan Soenen
Bella Manshian
Shareen H Doake
Stefaan De Smedt
Kevin Braeckmans
A1
Journal Article
in
ACTA BIOMATERIALIA
2013
Focal delivery of AAV2/1-transgenes into the rat brain by localized ultrasound-induced BBB opening
Angelika Alonso
Eileen Reinz
Barbara Leuchs
Juergen Kleinschmidt
Marc Fatar
Bart Geers
Ine Lentacker
Michael G. Hennerici
Stefaan De Smedt
Stephen Meairs
A1
Journal Article
in
MOLECULAR THERAPY-NUCLEIC ACIDS
2013
In vivo disassembly of IV administered siRNA matrix nanoparticles at the renal filtration barrier
Broes Naeye
Hendrik Deschout
Vicky Caveliers
Benedicte Descamps
Kevin Braeckmans
Christian Vanhove
Jo Demeester
Tony Lahoutte
Stefaan De Smedt
Koen Raemdonck
A1
Journal Article
in
BIOMATERIALS
2013
Injectable drug-loaded microbubbles : a magic bullet for image-guided cancer therapy?
Bart Geers
Stefaan De Smedt
Jo Demeester
Ine Lentacker
Dissertation
2013
Innate immune response and programmed cell death following carrier-mediated delivery of unmodified mRNA to respiratory cells
Oliwia Andries
Marina De Filette
Stefaan De Smedt
Jo Demeester
Mario Van Poucke
Luc Peelman
Niek Sanders
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2013
Light-addressable capsules as caged compound matrix for controlled triggering of cytosolic reactions
Markus Ochs
Susana Carregal-Romero
Joanna Rejman
Kevin Braeckmans
Stefaan De Smedt
Wolfgang Parak
A1
Journal Article
in
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
2013
Lipoplexes carrying mRNA encoding Gag protein modulate dendritic cells to stimulate HIV-specific immune responses
Winni De Haes
Joanna Rejman
Charlotte Pollard
Céline Merlin
Marc Vekemans
Eric Florence
Stefaan De Smedt
Johan Grooten
Guido Vanham
Stefaan De Koker
Ellen Van Gulck
A1
Journal Article
in
NANOMEDICINE
2013
Measuring the intravitreal mobility of nanomedicines with single-particle tracking microscopy
Thomas Martens
Dries Vercauteren
Katrien Forier
Hendrik Deschout
Katrien Remaut
Rik Paesen
Marcel Ameloot
Johan FJ Engbersen
Jo Demeester
Stefaan De Smedt
Kevin Braeckmans
A1
Journal Article
in
NANOMEDICINE
2013
Noncoding DNA in lipofection of HeLa cells: a few insights
Nathalie Symens
Joanna Rejman
Bart Lucas
Jo Demeester
Stefaan De Smedt
Katrien Remaut
A1
Journal Article
in
MOLECULAR PHARMACEUTICS
2013
Polysaccharide-based nucleic acid nanoformulations
Koen Raemdonck
Thomas F Martens
Kevin Braeckmans
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
ADVANCED DRUG DELIVERY REVIEWS
2013
Rectangle FRAP for measuring diffusion with a laser scanning microscope
Ranhua Xiong
Hendrik Deschout
Jo Demeester
Stefaan De Smedt
Kevin Braeckmans
Bookchapter
in
Fluorescence spectroscopy and microscopy : methods and protocols
2013
Targeted liposome-loaded microbubbles for cell-specific ultrasound-triggered drug delivery
Bart Geers
Olivier De Wever
Jo Demeester
Marc Bracke
Stefaan De Smedt
Ine Lentacker
A1
Journal Article
in
SMALL
2013
The biocompatibility of nanosized materials: intracellular nanoparticle stability and effects on toxicity and particle functionality
Stefaan Soenen
Stefaan De Smedt
Kevin Braeckmans
P1
Conference
2013
The influence of natural pulmonary surfactant on the efficacy of siRNA-loaded dextran nanogels
Lynn De Backer
Kevin Braeckmans
Jo Demeester
Stefaan De Smedt
Koen Raemdonck
A1
Journal Article
in
NANOMEDICINE
2013
Transport of nanoparticles in cystic fibrosis sputum and bacterial biofilms by single-particle tracking microscopy
Katrien Forier
Anne-Sophie Messiaen
Koen Raemdonck
Hendrik Deschout
Joanna Rejman
Frans De Baets
Hans Nelis
Stefaan De Smedt
Jo Demeester
Tom Coenye
Kevin Braeckmans
A1
Journal Article
in
NANOMEDICINE
2013
Turning a frown upside down: exploiting nanoparticle toxicity for anticancer therapy
Stefaan Soenen
Jo Demeester
Stefaan De Smedt
Kevin Braeckmans
A1
Journal Article
in
NANO TODAY
2013
Type I IFN counteracts the induction of antigen-specific immune responses by lipid-based delivery of mRNA vaccines
Charlotte Pollard
Joanna Rejman
Winni De Haes
Bernard Verrier
Ellen Van Gulck
Thomas Naessens
Stefaan De Smedt
Pieter Bogaert
Johan Grooten
Guido Vanham
Stefaan De Koker
A1
Journal Article
in
MOLECULAR THERAPY
2013
2012
Activation of pluripotency-associated genes in mouse embryonic fibroblasts by non-viral transfection with in vitro-derived mRNAs encoding Oct4, Sox2, Klf4 and cMyc
Geertrui Tavernier
Katharina Wolfrum
Jo Demeester
Stefaan De Smedt
James Adjaye
Joanna Rejman
A1
Journal Article
in
BIOMATERIALS
2012
An ex vivo assay to measure the mobility inside the eye of nanomedicines for retinal gene therapy
Thomas Martens
Dries Vercauteren
Katrien Forier
Hendrik Deschout
Katrien Remaut
Jo Demeester
Stefaan De Smedt
Kevin Braeckmans
C3
Conference
2012
Bio-inspired surfactant-modified dextran nanogels mediate enhanced intracellular siRNA delivery
Lynn De Backer
Jo Demeester
Stefaan De Smedt
Koen Raemdonck
C3
Conference
2012
Comparison of polymeric siRNA nanocarriers in a murine LPS-activated macrophage cell line: gene silencing, toxicity and off-target gene expression
Linda B Jensen
Joscha Griger
Broes Naeye
Amir K Varkouhi
Koen Raemdonck
Raymond Schiffelers
Twan Lammers
Gert Storm
Stefaan De Smedt
Brian S Sproat
Hanne M Nielsen
Camilla Foged
A1
Journal Article
in
PHARMACEUTICAL RESEARCH
2012
Comparison of the gene transfer efficiency of mRNA/GL67 and pDNA/GL67 complexes in respiratory cells
Oliwia Andries
Marina De Filette
Joanna Rejman
Stefaan De Smedt
Jo Demeester
Mario Van Poucke
Luc Peelman
Cindy Peleman
Tony Lahoutte
Niek Sanders
A1
Journal Article
in
MOLECULAR PHARMACEUTICS
2012
Crucial factors and emerging concepts in ultrasound-triggered drug delivery
Bart Geers
Heleen Dewitte
Stefaan De Smedt
Ine Lentacker
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2012
Cytotoxic effects of gold nanoparticles : a multiparametric study
Stefaan Soenen
Bella Manshian
José María Montenegro
Faheem Amin
Björn Meermann
Toke Thiron
Maria Cornelissen
Frank Vanhaecke
Shareen Doak
Wolfgang J Parak
Stefaan De Smedt
Kevin Braeckmans
A1
Journal Article
in
ACS NANO
2012
Delivery vehicles carrying antigens to dendritic cells
Marie-Luce De Temmerman
Stefaan De Smedt
Jo Demeester
Joanna Rejman
Dissertation
2012
Efficient transfection of hepatocytes mediated by mRNA complexed to galactosylated cyclodextrins
Nathalie Symens
Alejandro Méndez-Ardoy
Alejandro Diaz-Moscoso
Elena Sánchez-Fernéndez
Katrien Remaut
Jo Demeester
José M García Fernández
Stefaan De Smedt
Joanna Rejman
A1
Journal Article
in
BIOCONJUGATE CHEMISTRY
2012
Electrospun cellulose acetate phthalate fibers for semen induced anti-HIV vaginal drug delivery
Chaobo Huang
Stefaan Soenen
Ellen van Gulck
Guido Vanham
Joanna Rejman
Serge Van Calenbergh
Chris Vervaet
Tom Coenye
Hans Verstraelen
Marleen Temmerman
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
BIOMATERIALS
2012
Elucidating the pre- and post-nuclear intracellular processing of 1,4-dihydropyridine based gene delivery carriers
Zanna Hyvönen
Vesa Hämäläinen
Marika Ruponen
Bart Lucas
Joanna Rejman
Dries Vercauteren
Jo Demeester
Stefaan De Smedt
Kevin Braeckmans
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2012
Evaluation of small interfering RNA delivery by nanoparticle-loaded tumoritropic cells
Laura Wayteck
Stefaan De Smedt
Koen Raemdonck
C3
Conference
2012
Internalization of mRNA lipoplexes by dendritic cells
Winni De Haes
Greet Van Mol
Céline Merlin
Stefaan De Smedt
Guido Vanham
Joanna Rejman
A1
Journal Article
in
MOLECULAR PHARMACEUTICS
2012
Intracellular drug delivery in Leishmania-infected macrophages: evaluation of saponin-loaded PLGA nanoparticles
H Van De Ven
M Vermeersch
Roosmarijn Vandenbroucke
A Matheeussen
S Apers
W Weyenberg
Stefaan De Smedt
P Cos
L Maes
A Ludwig
A1
Journal Article
in
JOURNAL OF DRUG TARGETING
2012
Intracellular partitioning of cell organelles and extraneous nanoparticles during mitosis
Nathalie Symens
Stefaan Soenen
Joanna Rejman
Kevin Braeckmans
Stefaan De Smedt
Katrien Remaut
A1
Journal Article
in
ADVANCED DRUG DELIVERY REVIEWS
2012
Investigating the toxic effects of iron oxide nanoparticles
Stefaan Soenen
Marcel De Cuyper
Stefaan De Smedt
Kevin Braeckmans
A1
Journal Article
in
Methods in Enzymology
2012
Limitations and caveats of magnetic cell labeling using transfection agent complexed iron oxide nanoparticles
Stefaan Soenen
Stefaan De Smedt
Kevin Braeckmans
A1
Journal Article
in
CONTRAST MEDIA & MOLECULAR IMAGING
2012
Lipo- and polyplex-mediated mRNA delivery and its application in reprogramming of fibroblasts towards pluripotency
Geertrui Tavernier
Stefaan De Smedt
Joanna Rejman
James Adjaye
Dissertation
2012
Liposome based systems for systemic siRNA delivery: stability in blood sets the requirements for optimal carrier design
Kevin Buyens
Stefaan De Smedt
Kevin Braeckmans
Jo Demeester
Liesbeth Peeters
Leo A van Grunsven
Xavier de Mollerat du Jeu
Rupa Sawant
Vladimir Torchilin
Katarina Farkasova
Manfred Ogris
Niek Sanders
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2012
Magnetic electrospun fibers for cancer therapy
Chaobo Huang
Stefaan Soenen
Joanna Rejman
Jesse Trekker
Liu Chengxun
Liesbet Lagae
Wim Ceelen
Claire Wilhelm
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
ADVANCED FUNCTIONAL MATERIALS
2012
Matrix systems for siRNA delivery
Broes Naeye
Koen Raemdonck
Katrien Remaut
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
CURRENT TOPICS IN MEDICINAL CHEMISTRY
2012
Modulation of dendritic cells by lipid grafted polyelectrolyte microcapsules
Marie-Luce De Temmerman
Joanna Rejman
Bart Lucas
Roosmarijn Vandenbroucke
Claude Libert
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
ADVANCED FUNCTIONAL MATERIALS
2012
On the cellular processing of non-viral nanomedicines for nucleic acid delivery: mechanisms and methods
Dries Vercauteren
Joanna Rejman
Thomas Martens
Jo Demeester
Stefaan De Smedt
Kevin Braeckmans
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2012
Overcoming intracellular barriers in non-viral gene delivery : chromatin targeting, messenger RNA and non-coding DNA
Nathalie Symens
Stefaan De Smedt
Katrien Remaut
Joanna Rejman
Dissertation
2012
Polyelectrolyte LbL microcapsules versus PLGA microparticles for immunization with a protein antigen
Marie-Luce De Temmerman
Joanna Rejman
Roosmarijn Vandenbroucke
Stefaan De Koker
Claude Libert
Johan Grooten
Jo Demeester
Bruno Gander
Stefaan De Smedt
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2012
Tailoring layer-by-layer capsules for biomedical applications
Marie-Luce De Temmerman
Jo Demeester
Stefaan De Smedt
Joanna Rejman
A1
Journal Article
in
NANOMEDICINE
2012
The cytotoxic and immunogenic hurdles associated with non-viral mRNA-mediated reprogramming of human fibroblasts
Katharina Drews
Geertrui Tavernier
Jo Demeester
Hans Lehrach
Stefaan De Smedt
Joanna Rejman
James Adjaye
A1
Journal Article
in
BIOMATERIALS
2012
The cytotoxic effects of polymer-coated quantum dots and restrictions for live cell applications
Stefaan Soenen
Jo Demeester
Stefaan De Smedt
Kevin Braeckmans
A1
Journal Article
in
BIOMATERIALS
2012
The mechanisms behind sonoporation through the eyes of an AAV-vector
Bart Geers
Ine Lentacker
Angelika Alonso
Niek Sanders
Jo Demeester
Stephen Meairs
Stefaan De Smedt
A2
Journal Article
in
PUBLICATIONS QUARTERLY / AMERICAN CHEMICAL SOCIETY
2012
siRNA and pharmacological inhibition of endocytic pathways to characterize the differential role of macropinocytosis and the actin cytoskeleton on cellular uptake of dextran and cationic cell penetrating peptides octaarginine (R8) and HIV-Tat
M. Al Soraj
L. He
Karen Peynshaert
J. Cousaert
Dries Vercauteren
Kevin Braeckmans
Stefaan De Smedt
Arwin T. Jones
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2012
2011
Assessing dextran nanogels for intravenous small interfering RNA delivery
Broes Naeye
Stefaan De Smedt
Jo Demeester
Koen Raemdonck
Dissertation
2011
Cellular toxicity of inorganic nanoparticles: common aspects and guidelines for improved nanotoxicity evaluation
Stefaan Soenen
Pilar Rivera-Gil
José-María Montenegro
Wolfgang J Parak
Stefaan De Smedt
Kevin Braeckmans
A1
Journal Article
in
NANO TODAY
2011
Dynamic colocalization microscopy to characterize intracellular trafficking of nanomedicines
Dries Vercauteren
Hendrik Deschout
Katrien Remaut
Johan FJ Engbersen
Arwyn T Jones
Jo Demeester
Stefaan De Smedt
Kevin Braeckmans
A1
Journal Article
in
ACS NANO
2011
Elucidating the mechanisms behind sonoporation with adeno-associated virus-loaded microbubbles
Bart Geers
Ine Lentacker
Angelika Alonso
Niek Sanders
Jo Demeester
Stephen Meairs
Stefaan De Smedt
A1
Journal Article
in
MOLECULAR PHARMACEUTICS
2011
Encapsulation performance of layer-by-layer microcapsules for proteins
Marie-Luce De Temmerman
Jo Demeester
Filip De Vos
Stefaan De Smedt
A1
Journal Article
in
BIOMACROMOLECULES
2011
Exploring electrospun fibers for pharmaceutical use
Chaobo Huang
Stefaan De Smedt
Jo Demeester
Dissertation
2011
Flotillin-dependent endocytosis and a phagocytosis-like mechanism for cellular internalization of disulfide-based poly(amido amine)/DNA polyplexes
Dries Vercauteren
Martin Piest
Leonardus J van der AA
Monerah Al Soraj
Arwyn T Jones
Johan FJ Engbersen
Stefaan De Smedt
Kevin Braeckmans
A1
Journal Article
in
BIOMATERIALS
2011
Fluorescence recovery after photobleaching on the confocal laser-scanning microscope: generalized model without restriction on the size of the photobleached disk
Nick Smisdom
Kevin Braeckmans
Hendrik Deschout
Martin vandeVen
Jean-Michel Rigo
Stefaan De Smedt
Marcel Ameloot
A1
Journal Article
in
JOURNAL OF BIOMEDICAL OPTICS
2011
Fluorescence single particle tracking for sizing of nanoparticles in undiluted biological fluids
Kevin Braeckmans
Kevin Buyens
Wim Bouquet-Geerardyn
Chris Vervaet
Philippe Joye
Filip De Vos
Laurent Plawinski
Loïc Doeuvre
Eduardo Angles-Cano
Niek Sanders
Jo Demeester
Stefaan De Smedt
P1
Conference
2011
Gene and cell therapy for cystic fibrosis : from bench to bedside
Massimo Conese
Fiorentina Ascenzioni
A. Christopher Boyd
Charles Coutelle
Ida De Fino
Stefaan De Smedt
Joanna Rejman
Joseph Rosenecker
Dirk Schindelhauer
Bob J. Scholte
A1
Journal Article
in
JOURNAL OF CYSTIC FIBROSIS
2011
Hemocompatibility of siRNA loaded dextran nanogels
Broes Naeye
Hendrik Deschout
Magnus Roding
Mats Rudemo
Joris Delanghe
Katrien Devreese
Jo Demeester
Kevin Braeckmans
Stefaan De Smedt
Koen Raemdonck
A1
Journal Article
in
BIOMATERIALS
2011
Lyophilization of protein-loaded polyelectrolyte microcapsules
Marie-Luce De Temmerman
Joanna Rejman
Johan Grooten
Thomas De Beer
Chris Vervaet
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
PHARMACEUTICAL RESEARCH
2011
Nuclear inclusion of nontargeted and chromatin-targeted polystyrene beads and plasmid DNA containing nanoparticles
Nathalie Symens
Rudolf Walczak
Jo Demeester
Iain Mattaj
Stefaan De Smedt
Katrien Remaut
A1
Journal Article
in
MOLECULAR PHARMACEUTICS
2011
On the cellular processing of nanomedicines for retinal gene therapy and their suitability for intravitreal injections
Dries Vercauteren
Kevin Braeckmans
Stefaan De Smedt
Dissertation
2011
Particulate vaccines: on the quest for optimal delivery and immune response
Marie-Luce De Temmerman
Joanna Rejman
Jo Demeester
Darrell J Irvine
Bruno Gander
Stefaan De Smedt
A1
Journal Article
in
DRUG DISCOVERY TODAY
2011
Protein macromonomers containing reduction-sensitive linkers for covalent immobilization and glutathione triggered release from dextran hydrogels
Ellen Verheyen
Steffen van der Wal
Hendrik Deschout
Kevin Braeckmans
Stefaan De Smedt
Arjan Barendregt
Wim E Hennink
Cornelus F van Nostrum
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2011
Self-assembled liposome-loaded microbubbles: the missing link for safe and efficient ultrasound triggered drug-delivery
Bart Geers
Ine Lentacker
Niek Sanders
Jo Demeester
Stephen Meairs
Stefaan De Smedt
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2011
Stimuli-responsive electrospun fibers and their applications
Chaobo Huang
Stefaan Soenen
Joanna Rejman
Bart Lucas
Kevin Braeckmans
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
CHEMICAL SOCIETY REVIEWS
2011
mRNA as gene therapeutic: how to control protein expression
Geertrui Tavernier
Oliwia Andries
Jo Demeester
Niek Sanders
Stefaan De Smedt
Joanna Rejman
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2011
mRNA-Lipoplex loaded microbubble contrast agents for ultrasound-assisted transfection of dendritic cells
Marie-Luce De Temmerman
Heleen Dewitte
Roosmarijn Vandenbroucke
Bart Lucas
Claude Libert
Jo Demeester
Stefaan De Smedt
Ine Lentacker
Joanna Rejman
A1
Journal Article
in
BIOMATERIALS
2011
2010
Advanced fluorescence microscopy methods illuminate the transfection pathway of nucleic acid nanoparticles
Kevin Braeckmans
Kevin Buyens
Broes Naeye
Dries Vercauteren
Hendrik Deschout
Koen Raemdonck
Katrien Remaut
Niek Sanders
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2010
Biodegradable polyelectrolyte microcapsules: antigen delivery tools with Th17 skewing activity after pulmonary delivery
Stefaan De Koker
Thomas Naessens
Bruno De Geest
Pieter Bogaert
Jo Demeester
Stefaan De Smedt
Johan Grooten
A1
Journal Article
in
JOURNAL OF IMMUNOLOGY
2010
Colour-coded microcarriers: made to move
Kevin Braeckmans
Stefaan De Smedt
Other
2010
Design and evaluation of doxorubicin-containing microbubbles for ultrasound-triggered doxorubicin delivery: cytotoxicity and mechanisms involved
Ine Lentacker
Bart Geers
Jo Demeester
Stefaan De Smedt
Niek Sanders
A1
Journal Article
in
MOLECULAR THERAPY
2010
Efficient delivery of intact phosphodiester oligonucleotides by poly-β-amino esters
Katrien Remaut
Nathalie Symens
Bart Lucas
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2010
Flexible nanosomes (SECosomes) enable efficient siRNA delivery in cultured primary skin cells and in the viable epidermis of ex vivo human skin
Barbara Geusens
Mireille Van Gele
Sien Braat
Stefaan De Smedt
Marc CA Stuart
Tarl W Prow
Washington Sanchez
Michael S Roberts
Niek Sanders
Jo Lambert
A1
Journal Article
in
ADVANCED FUNCTIONAL MATERIALS
2010
High intracellular iron oxide nanoparticle concentrations affect cellular cytoskeleton and focal adhesion kinase-mediated signaling
Stefaan Soenen
Nele Nuytten
Simon De Meyer
Stefaan De Smedt
Marcel De Cuyper
A1
Journal Article
in
SMALL
2010
Impact of chronic pulmonary infection with Pseudomonas aeruginosa on transfection mediated by viral and nonviral vectors
Joanna Rejman
Ida De Fino
Moira Paroni
Alessandra Bragonzi
Jo Demeester
Stefaan De Smedt
Massimo Conese
A1
Journal Article
in
HUMAN GENE THERAPY
2010
Insights in cellular uptake mechanisms of pDNA-polycationic amphiphilic cyclodextrin nanoparticles (CDplexes)
Alejandro Díaz-Moscoso
Dries Vercauteren
Joanna Rejman
Juan M Benito
Carment Ortiz Mellet Mellet
Stefaan De Smedt
José M García Fernández
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2010
Interactions of siRNA loaded dextran nanogel with blood cells
Broes Naeye
Koen Raemdonck
Jo Demeester
Stefaan De Smedt
C3
Conference
2010
Monitoring the disassembly of siRNA polyplexes in serum is crucial for predicting their biological efficacy
Kevin Buyens
Martin Meyer
Ernst Wagner
Jo Demeester
Stefaan De Smedt
Niek Sanders
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2010
Optimizing siRNA-nanocarriers for systemic delivery by monitoring their behavior in blood
Kevin Buyens
Stefaan De Smedt
Niek Sanders
Dissertation
2010
PEGylation of biodegradable dextran nanogels for siRNA delivery
Broes Naeye
Koen Raemdonck
Katrien Remaut
B Sproat
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
2010
Photopolymerized thermosensitive poly(HPMAlactate)-PEG-based hydrogels : effect of network design on mechanical properties, degradation, and release behavior
Roberta Censi
Tina Vermonden
Hendrik Deschout
Kevin Braeckmans
Piera di Martino
Stefaan De Smedt
Cornelus F van Nostrum
Wim E Hennink
A1
Journal Article
in
BIOMACROMOLECULES
2010
Polyelectrolyte capsules-containing HIV-1 p24 and poly I:C modulate dendritic cells to stimulate HIV-1-specific immune responses
Winni De Haes
Stefaan De Koker
Charlotte Pollard
Derek Atkinson
Erika Vlieghe
Jessy Hoste
Joanna Rejman
Stefaan De Smedt
Johan Grooten
Guido Vanham
Ellen Van Gulck
A1
Journal Article
in
MOLECULAR THERAPY
2010
Prolonged gene silencing by combining siRNA nanogels and photochemical internalization
Koen Raemdonck
Broes Naeye
A Hogset
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2010
Pulmonary delivery of mRNA: in vitro and in vivo evaluation
Oliwia Andries
Joanna Rejman
Cindy Peleman
Tony Lahoutte
Stefaan De Smedt
Jo Demeester
Niek Sanders
C3
Conference
2010
Self-exploding capsules
Bruno De Geest
Stefaan De Koker
Jo Demeester
Stefaan De Smedt
Wim E Hennink
A1
Journal Article
in
POLYMER CHEMISTRY
2010
Single particle tracking
Kevin Braeckmans
Dries Vercauteren
Jo Demeester
Stefaan De Smedt
Bookchapter
in
Nanoscopy and multidimensional optical fluorescence microscopy
2010
Sizing nanomatter in biological fluids by fluorescence single particle tracking
Kevin Braeckmans
Kevin Buyens
Wim Bouquet-Geerardyn
Chris Vervaet
Philippe Joye
Filip De Vos
Laurent Plawinski
Loic Doeuvre
Eduardo Angles-Cano
Niek Sanders
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
NANO LETTERS
2010
The use of inhibitors to study endocytic pathways of gene carriers: optimization and pitfalls
Dries Vercauteren
Roosmarijn Vandenbroucke
Arwyn T Jones
Joanna Rejman
Jo Demeester
Stefaan De Smedt
Niek Sanders
Kevin Braeckmans
A1
Journal Article
in
MOLECULAR THERAPY
2010
Transport and delivery of antimicrobial agents in Burkholderia biofilms
Katrien Forier
Anne-Sophie Messiaen
Tom Coenye
Hans Nelis
Shari Celen
Serge Van Calenbergh
Stefaan De Smedt
Jo Demeester
Kevin Braeckmans
C3
Conference
2010
Unbreakable codes in electrospun fibers : digitally encoded polymers to stop medicine counterfeiting
Chaobo Huang
Bart Lucas
Chris Vervaet
Kevin Braeckmans
Serge Van Calenbergh
Izet Karalic
Mado Vandewoestyne
Dieter Deforce
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
ADVANCED MATERIALS
2010
Unbreakable codes in electrospun fibers to stop medicine counterfeiting
Chaobo Huang
Bart Lucas
Chris Vervaet
Kevin Braeckmans
Serge Van Calenbergh
Izet Karalic
Mado Vandewoestyne
Dieter Deforce
Jo Demeester
Stefaan De Smedt
C3
Conference
2010
Vaccination of turkeys against Chlamydophila psittaci through optimised DNA formulation and administration
Kristel Verminnen
Delphine Sylvie Anne Beeckman
Niek Sanders
Stefaan De Smedt
Daisy Vanrompay
A1
Journal Article
in
VACCINE
2010
mRNA transfection of cervical carcinoma and mesenchymal stem cells mediated by cationic carriers
Joanna Rejman
Geertrui Tavernier
Neda Bavarsad
Joseph Demeester
Stefaan De Smedt
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2010
siRNA containing nanoparticles: stability of encapsulation and particle size
Kevin Buyens
Kevin Braeckmans
Jo Demeester
Stefaan De Smedt
Niek Sanders
C3
Conference
2010
2009
Advanced nanogel engineering for drug delivery
Koen Raemdonck
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
Soft Matter
2009
Biodegradable Dextran Nanogels for RNA Interference: Focusing on Endosomal Escape and Intracellular siRNA Delivery
Koen Raemdonck
Broes Naeye
Kevin Buyens
Roosmarijn Vandenbroucke
A Hogset
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
Advanced Functional Materials
2009
Biodegradable dextran nanogels as functional carriers for the intracellular delivery of small interfering RNA
Koen Raemdonck
Stefaan De Smedt
Jo Demeester
Dissertation
2009
Cationic polymers to optimize aerosol delivery of a Chlamydophila psittaci DNA vaccine
Kristel Verminnen
Niek Sanders
Stefaan De Smedt
Daisy Vanrompay
C3
Conference
2009
Design and evaluation of drug loaded microbubbles for ultrasound guided cancer therapy
Ine Lentacker
Niek Sanders
Stefaan De Smedt
Jo Demeester
Dissertation
2009
Development of a sensitive diagnostic multiplex platform based on digitally encoded microcarriers
Stefaan Derveaux
Jo Demeester
Stefaan De Smedt
Dissertation
2009
Drug loaded microbubble design for ultrasound triggered delivery
Ine Lentacker
Stefaan De Smedt
Niek Sanders
A1
Journal Article
in
SOFT MATTER
2009
Elucidating the Encapsulation of Short Interfering RNA in PEGylated Cationic Liposomes
Kevin Buyens
Jo Demeester
Stefaan De Smedt
Niek Sanders
A1
Journal Article
in
Langmuir
2009
Evaluation of ethosomes for delivery of siRNA into cultured primary melanocytes and skin
Barbara Geusens
Sien Braat
M Stuart
Stefaan De Smedt
Niek Sanders
T Prow
M Roberts
Jo Lambert
Mireille Van Gele
C3
Conference
2009
Extracellular barriers in respiratory gene therapy
Niek Sanders
Carsten Rudolph
Kevin Braeckmans
Stefaan De Smedt
Jo Demeester
A1
Journal Article
in
ADVANCED DRUG DELIVERY REVIEWS
2009
Photopolymerized thermosensitive hydrogels for tailorable diffusion-controlled protein delivery
R Censi
T Vermonden
MJ van Steenbergen
Hendrik Deschout
Kevin Braeckmans
Stefaan De Smedt
CF van Nostrum
P di Martino
WE Hennink
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2009
Polyelectrolyte Microcapsules as Antigen Delivery Vehicles To Dendritic Cells: Uptake, Processing, and Cross-Presentation of Encapsulated Antigens
Stefaan De Koker
Bruno De Geest
Satwinder Singh
Riet De Rycke
Thomas Naessens
Yvette Van Kooyk
Jo Demeester
Stefaan De Smedt
Johan Grooten
A1
Journal Article
in
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
2009
Polyelectrolyte microcapsules for biomedical applications
Bruno De Geest
Stefaan De Koker
GB Sukhorukov
O Kreft
WJ Parak
Andre Skirtach
Jo Demeester
Stefaan De Smedt
Wim E Hennink
A1
Journal Article
in
Soft Matter
2009
Protein-Release Behavior of Self-Assembled PEG-beta-Cyclodextrin/PEG-Cholesterol Hydrogels
F van de Manakker
Kevin Braeckmans
N el Morabit
Stefaan De Smedt
CF van Nostrum
WE Hennink
A1
Journal Article
in
ADVANCED FUNCTIONAL MATERIALS
2009
Pulsed in vitro release and in vivo behavior of exploding microcapsules
Bruno De Geest
Stefaan De Koker
Jo Demeester
Stefaan De Smedt
WE Hennink
A1
Journal Article
in
Journal of Controlled Release
2009
Stability of siRNA polyplexes from poly(ethylenimine) and poly(ethylenimine)-g-poly(ethylene glycol) under in vivo conditions: Effects on pharmacokinetics and biodistribution measured by Fluorescence Fluctuation Spectroscopy and Single Photon Emission Computed Tomography (SPECT) imaging
OM Merkel
D Librizzi
A Pfestroff
T Schurrat
Kevin Buyens
Niek Sanders
Stefaan De Smedt
M Behe
T Kissel
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2009
Stable long-term intracellular labelling with fluorescently tagged cationic magnetoliposomes
Stefaan JH Soenen
Dries Vercauteren
Kevin Braeckmans
Wim Noppe
Stefaan De Smedt
Marcel De Cuyper
A1
Journal Article
in
CHEMBIOCHEM
2009
The role of nanoparticle concentration-dependent induction of cellular stress in the internalization of non-toxic cationic magnetoliposomes
Stefaan Soenen
Eszter Illyes
Dries Vercauteren
Kevin Braeckmans
Zsuzsa Majer
Stefaan De Smedt
Marcel De Cuyper
A1
Journal Article
in
BIOMATERIALS
2009
Ultradeformable cationic liposomes for delivery of small interfering RNA (siRNA) into human primary melanocytes
Barbara Geusens
Jo Lambert
Stefaan De Smedt
Kevin Buyens
Niek Sanders
Mireille Van Gele
A1
Journal Article
in
Journal of Controlled Release
2009
Ultrasound exposure of lipoplex loaded microbubbles facilitates direct cytoplasmic entry of the lipoplexes
Ine Lentacker
Nan Wang
Roosmarijn Vandenbroucke
Jo Demeester
Stefaan De Smedt
Niek Sanders
A1
Journal Article
in
MOLECULAR PHARMACEUTICS
2009
2008
A fast and sensitive method for measuring the integrity of siRNA-carrier complexes in full human serum
Kevin Buyens
Bart Lucas
Koen Raemdonck
Kevin Braeckmans
J VERCAMMEN
J HENDRIX
Y ENGELBORGHS
Stefaan De Smedt
Niek Sanders
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2008
A new FRAP/FRAPa method for three-dimensional diffusion measurements based on multiphoton excitation microscopy
Davide Mazza
Kevin Braeckmans
Francesca Cella
Ilaria Testa
Dries Vercauteren
Jo Demeester
Stefaan De Smedt
Alberto Diaspro
A1
Journal Article
in
BIOPHYSICAL JOURNAL
2008
Advanced fluorescence microscopy methods illuminate the transfection pathway
Stefaan De Smedt
Kevin Braeckmans
Dries Vercauteren
Jo Demeester
C3
Conference
2008
Biodegradable microcapsules designed via "click" chemistry
Bruno De Geest
Wim Van Camp
Filip Du Prez
Stefaan De Smedt
Jo Demeester
W HENNINK
C3
Conference
2008
Biodegradable microcapsules designed via 'click' chemistry
Bruno De Geest
Wim Van Camp
Filip Du Prez
Stefaan De Smedt
Jo Demeester
WE HENNINK
A1
Journal Article
in
CHEMICAL COMMUNICATIONS
2008
Biodegradable microgels by click chemistry
Bruno De Geest
Wim Van Camp
Filip Du Prez
Jo Demeester
Stefaan De Smedt
Wim E Hennink
C3
Conference
2008
Biodegradable microgels by click chemistry
Bruno De Geest
Wim Van Camp
Filip Du Prez
Jo Demeester
Stefaan De Smedt
W HENNINK
C3
Conference
2008
Biodegradable polymers as non-viral carriers for plasmid DNA delivery
J LUTEN
CF VAN NOSTRUIN
Stefaan De Smedt
WE HENNINK
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2008
Can ultrasound solve the transport barrier of the neural retina?
Liesbeth Peeters
Ine Lentacker
Roosmarijn Vandenbroucke
Bart Lucas
Jo Demeester
Niek Sanders
Stefaan De Smedt
A1
Journal Article
in
PHARMACEUTICAL RESEARCH
2008
Cationic polymers to optimize aerosol delivery of a Chlamydophila psittaci DNA vaccine
Kristel Verminnen
Niek Sanders
Stefaan De Smedt
Daisy Vanrompay
C3
Conference
2008
Cationic polymers to optimize aerosol delivery of a Chlamydophila psittaci DNA vaccine
Kristel Verminnen
Niek Sanders
Stefaan De Smedt
Daisy Vanrompay
C3
Conference
2008
Circumventing the endocytotic uptake of highly PEGylated lipoplexes by using lipoplex loaded microbubbles and ultrasound can drastically increase their transfection efficiency
Ine Lentacker
Stefaan De Smedt
Niek Sanders
C3
Conference
2008
Degradable microgels and hollow capsules by 'click' chemistry
Bruno De Geest
Wim Van Camp
Filip Du Prez
Jo Demeester
Stefaan De Smedt
W Hennink
C3
Conference
2008
Degradable multilayer films and hollow capsules via a 'Click' strategy
Bruno De Geest
Wim Van Camp
Filip Du Prez
Stefaan De Smedt
Jo Demeester
WE HENNINK
A1
Journal Article
in
MACROMOLECULAR RAPID COMMUNICATIONS
2008
Dextran microgels for time-controlled delivery of siRNA
Koen Raemdonck
Tinneke Van Thienen
Roosmarijn Vandenbroucke
Niek Sanders
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
ADVANCED FUNCTIONAL MATERIALS
2008
Effect of particle size and charge on the network properties of microsphere-based hydrogels
SR VAN TOMME
CF VAN NOSTRUM
M DIJKSTRA
Stefaan De Smedt
WE HENNINK
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
2008
Evaluation of Digitally Encoded Layer-by-layer Coated Microparticles as Cell Carriers
Farzaneh Fayazpour
Bart Lucas
Roosmarijn Vandenbroucke
Stefaan Derveaux
Jan Tavernier
Sam Lievens
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
ADVANCED FUNCTIONAL MATERIALS
2008
Evaluation of encoded layer-by-layer coated microparticles as protease sensors
Barbara Stubbe
Kris Gevaert
Stefaan Derveaux
Kevin Braeckmans
Bruno De Geest
Marc Goethals
Joël Vandekerckhove
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
ADVANCED FUNCTIONAL MATERIALS
2008
Layer-by-layer coated digitally encoded microcarriers for quantification of proteins in serum and plasma
Stefaan Derveaux
Barbara Stubbe
C ROELANT
M LEBLANS
Bruno De Geest
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
ANALYTICAL CHEMISTRY
2008
Loading of PEGylated siRNA lipoplexes on microbubbles restores their siRNA delivery capacity in the presence of ultrasound
Roosmarijn Vandenbroucke
Ine Lentacker
Jo Demeester
Stefaan De Smedt
Niek Sanders
C1
Conference
2008
Maintaining the silence: reflections on long-term RNAi
Koen Raemdonck
Roosmarijn Vandenbroucke
Jo Demeester
Niek Sanders
Stefaan De Smedt
A1
Journal Article
in
DRUG DISCOVERY TODAY
2008
Microcapsules Ejecting Nanosized Species into the Environment
Bruno De Geest
MJ MCSHANE
Jo Demeester
Stefaan De Smedt
WE HENNINK
A1
Journal Article
in
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
2008
New strategies for nucleic acid delivery to conquer cellular and nuclear membranes
Ine Lentacker
Roosmarijn Vandenbroucke
Bart Lucas
Jo Demeester
Stefaan De Smedt
Niek Sanders
A1
Journal Article
in
Journal of Controlled Release
2008
Opportunities for digitally encoded microcarriers in pharmacy and cell-based assays
Farzaneh Fayazpour
Bart Lucas
N HUYGEBAERT
Kevin Braeckmans
Stefaan Derveaux
Roosmarijn Vandenbroucke
Jean Paul Remon
Jo Demeester
Chris Vervaet
Stefaan De Smedt
C1
Conference
2008
Prolonged gene silencing in hepatoma cells and primary hepatocytes after siRNA delivery with biodegradable poly(beta-amino esters)
Roosmarijn Vandenbroucke
Bruno De Geest
Jo Demeester
Stefaan De Smedt
Niek Sanders
C1
Conference
2008
Prolonged gene silencing in hepatoma cells and primary hepatocytes after small interfering RNA delivery with biodegradable poly(beta-amino esters)
Roosmarijn Vandenbroucke
Bruno De Geest
Stefan Bonné
M VINKEN
T VAN HAECKE
H HEIMBERG
E WAGNER
V ROGIERS
Stefaan De Smedt
Jo Demeester
Niek Sanders
A1
Journal Article
in
JOURNAL OF GENE MEDICINE
2008
Screening poly(ethyleneglycol) micro- and nanogels for drug delivery purposes
Tinneke Van Thienen
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2008
Self exploding microcapsules
Bruno De Geest
Stefaan De Koker
Jo Demeester
Stefaan De Smedt
Wim E Hennink
C3
Conference
2008
Self-Exploding Beads Releasing Microcarriers
Bruno De Geest
Stefaan De Koker
Kristof Immesoete
Jo Demeester
Stefaan De Smedt
WE HENNINK
A1
Journal Article
in
ADVANCED MATERIALS
2008
Stimuli-responsive polyelectrolyte microcapsules for biomedical applications
Bruno De Geest
A Skirtach
G Sukhorukov
Jo Demeester
Stefaan De Smedt
WE Hennink
C3
Conference
2008
Synergism between particle-based multiplexing and microfluidics technologies may bring diagnostics closer to the patient
Stefaan Derveaux
Barbara Stubbe
Kevin Braeckmans
C ROELANT
K SATO
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
2008
Ultrasound assisted siRNA delivery using PEG-siPlex loaded microbubbles
Roosmarijn Vandenbroucke
Ine Lentacker
Jo Demeester
Stefaan De Smedt
Niek Sanders
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2008
2007
Assessment of fluorescently labelled polyelectrolyte distribution in sludge flocs by confocal laser scanning microscopy
Daan Curvers
Hans Saveyn
Bart Lucas
Stefaan De Smedt
Lies Bonami
Filip Du Prez
Patric Van Oostveldt
Paul Van der Meeren
C1
Conference
2007
Can we better understand the intracellular behavior of DNA nanoparticles by fluorescence correlation spectroscopy?
Katrien Remaut
Bart Lucas
Koen Raemdonck
Kevin Braeckmans
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2007
Cell uptake, cytoplasmic diffusion and nuclear access of a 6.5 nm diameter dendrimer
P RUENRAROENGSAK
KT AL-JAMAL
N HARTELL
Kevin Braeckmans
Stefaan De Smedt
AT FLORENCE
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2007
Cellular entry pathway and gene transfer capacity of TAT-modified lipoplexes
Roosmarijn Vandenbroucke
Stefaan De Smedt
Jo Demeester
Niek Sanders
A1
Journal Article
in
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
2007
Challenges in non-viral ocular gene transfer
Liesbeth Peeters
Niek Sanders
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
BIOCHEMICAL SOCIETY TRANSACTIONS
2007
Digitally encoded drug tablets to combat counterfeiting
Farzaneh Fayazpour
Bart Lucas
N HUYGHEBAERT
Kevin Braeckmans
Stefaan Derveaux
BG STUBBE
Jean Paul Remon
Jo Demeester
Chris Vervaet
Stefaan De Smedt
A1
Journal Article
in
ADVANCED MATERIALS
2007
In vivo cellular uptake, degradation, and biocompatibility of polyelectrolyte microcapsules
Stefaan De Koker
Bruno De Geest
Claude Cuvelier
Liesbeth Ferdinande
Wies Deckers
WE HENNINK
Stefaan De Smedt
Nico Mertens
A1
Journal Article
in
ADVANCED FUNCTIONAL MATERIALS
2007
Influence of free chains on the swelling pressure of PEG-HEMA and dex-HEMA hydrogels
Tinneke Van Thienen
F HORKAY
Kevin Braeckmans
BG STUBBE
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2007
Line FRAP with the confocal laser scanning microscope for diffusion measurements in small regions of 3-D samples
Kevin Braeckmans
Katrien Remaut
Roosmarijn Vandenbroucke
Bart Lucas
Stefaan De Smedt
Jo Demeester
A1
Journal Article
in
BIOPHYSICAL JOURNAL
2007
Lipoplex-loaded microbubbles for gene delivery: A Trojan horse controlled by ultrasound
Ine Lentacker
Stefaan De Smedt
Jo Demeester
Veerle Van Marck
Marc Bracke
Niek Sanders
A1
Journal Article
in
ADVANCED FUNCTIONAL MATERIALS
2007
Mucolytic activity of bacterial and human chitinases
Niek Sanders
VGH EIJSLNK
PS VAN DEN PANGAART
RJJ VAN NEERVEN
PJ SIMONS
Stefaan De Smedt
Jo Demeester
A1
Journal Article
in
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
2007
Multifunctional layer-by-layer coating of digitally encoded microparticles
Stefaan Derveaux
Bruno De Geest
C ROELANT
Kevin Braeckmans
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
LANGMUIR
2007
Nuclear accumulation of plasmid DNA can be enhanced by non-selective gating of the nuclear pore
Roosmarijn Vandenbroucke
Bart Lucas
Jo Demeester
Stefaan De Smedt
Niek Sanders
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2007
Nuclear accumulation of plasmid DNA can be enhanced by non-selective gating of the nuclear pore
Roosmarijn Vandenbroucke
Bart Lucas
Jo Demeester
Stefaan De Smedt
Niek Sanders
C1
Conference
2007
Nucleic acid delivery: Where material sciences and bio-sciences meet
Katrien Remaut
Niek Sanders
Bruno De Geest
Kevin Braeckmans
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
MATERIALS SCIENCE & ENGINEERING R-REPORTS
2007
Pegylation of liposomes favours the endosornal degradation of the delivered phosphodiester oligonucleotides
Katrien Remaut
Bart Lucas
Kevin Braeckmans
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2007
Post-pegylated lipoplexes are promising vehicles for gene delivery in RPE cells
Liesbeth Peeters
Niek Sanders
A JONES
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2007
Protection of oligonucleotides against enzymatic degradation by pegylated and nonpegylated branched polyethyleneimine
Katrien Remaut
Bart Lucas
Koen Raemdonck
Kevin Braeckmans
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
BIOMACROMOLECULES
2007
Protein release from biodegradable dextran nanogels
Tinneke Van Thienen
Koen Raemdonck
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
LANGMUIR
2007
Release mechanisms for polyelectrolyte capsules
Bruno De Geest
Niek Sanders
GB SUKHORUKOV
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
CHEMICAL SOCIETY REVIEWS
2007
Self-rupturing and hollow microcapsules prepared from bio-polyelectrolyte-coated microgels
Bruno De Geest
C DEJUGNAT
M PREVOT
GB SUKHORUKOV
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
ADVANCED FUNCTIONAL MATERIALS
2007
Sensitive spectroscopic detection of large and denatured protein aggregates in solution by use of the fluorescent dye Nile red
M SUTTER
S OLIVEIRA
Niek Sanders
Bart Lucas
A VAN HOEK
MA HINK
AJWG VISSER
Stefaan De Smedt
WE HENNINK
W JISKOOT
A1
Journal Article
in
JOURNAL OF FLUORESCENCE
2007
Stimuli-responsive multilayered hybrid nanoparticle/polyelectrolyte capsules
Bruno De Geest
Andre Skirtach
Thomas De Beer
GB SUKHORUKOV
Lieven Bracke
Willy Baeyens
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
MACROMOLECULAR RAPID COMMUNICATIONS
2007
Ultrasound-triggered release from multilayered capsules
Bruno De Geest
Andre Skirtach
AA MAMEDOV
AA ANTIPOV
NA KOTOV
Stefaan De Smedt
GB SUKHORUKOV
A1
Journal Article
in
SMALL
2007
Wanted and unwanted properties of surface PEGylated nucleic acid nanoparticles in ocular gene transfer
Niek Sanders
Liesbeth Peeters
Ine Lentacker
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2007
2006
Anomalous photobleaching in fluorescence recovery after photobleaching measurements due to excitation saturation- a case study for fluorescein
Kevin Braeckmans
Barbara Stubbe
Katrien Remaut
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
JOURNAL OF BIOMEDICAL OPTICS
2006
Characterization of diffusion of macromolecules in konjac glucomannan solutions and gels by fluorescence recovery after photobleaching technique
F ALVAREZ-MANCENIDO
Kevin Braeckmans
Stefaan De Smedt
Jo Demeester
M LANDIN
R MARTINEZ-PACHECO
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2006
Characterization of the mode of incorporation of lipophilic compounds in solid dispersions at the nanoscale using fluorescence resonance energy transfer (FRET)
DJ VAN DROOGE
Kevin Braeckmans
WLJ HINRICHS
Katrien Remaut
Stefaan De Smedt
HW FRIJLINK
A1
Journal Article
in
MACROMOLECULAR RAPID COMMUNICATIONS
2006
Degradation behavior of dextran hydrogels composed of positively and negatively charged microspheres
SR VAN TOMME
CF VAN NOSTRUM
Stefaan De Smedt
WE HENNINK
A1
Journal Article
in
BIOMATERIALS
2006
Delivery of phosphodiester oligonucleotides: Can DOTAP/DOPE liposomes do the trick?
Katrien Remaut
Bart Lucas
Kevin Braeckmans
Niek Sanders
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
BIOCHEMISTRY
2006
Glucose-responsive polyelectrolyte capsules
Bruno De Geest
AM JONAS
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
LANGMUIR
2006
In situ analysis of single-stranded and duplex siRNA integrity in living cells
Koen Raemdonck
Katrien Remaut
Bart Lucas
Niek Sanders
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
BIOCHEMISTRY
2006
Influence of plasmid DNA topology on the transfection properties of DOTAP/DOPE lipoplexes
Katrien Remaut
Niek Sanders
Farzaneh Fayazpour
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2006
Intracellularly degradable polyelectrolyte microcapsules
Bruno De Geest
Roosmarijn Vandenbroucke
AM GUENTHER
GB SUKHORUKOV
WE HENNINK
Niek Sanders
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
ADVANCED MATERIALS
2006
Layer-by-layer coating of degradable microgels for pulsed drug delivery
Bruno De Geest
C DEJUGNAT
Ellen Verhoeven
GB SUKHORUKOV
AM JONAS
J PLAIN
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2006
Microbubbles which bind and protect DNA against nucleases
Ine Lentacker
Stefaan De Smedt
Jo Demeester
Niek Sanders
C3
Conference
2006
Physicochemical and transfection properties of cationic hydroxyethylcellulose/DNA nanoparticles
Farzaneh Fayazpour
Bart Lucas
C ALVAREZ-LORENZO
Niek Sanders
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
BIOMACROMOLECULES
2006
Pulsed drug delivery
Bruno De Geest
Els Mehuys
G Laekeman
Jo Demeester
Stefaan De Smedt
A2
Journal Article
in
Expert Opinion on Drug Delivery
2006
Role of magnesium in the failure of rhDNase therapy in patients with cystic fibrosis
Niek Sanders
H FRANCKX
K DE BOECK
Jurgen Haustraete
Stefaan De Smedt
Jo Demeester
A1
Journal Article
in
THORAX
2006
Self-exploding lipid-coated microgels
Bruno De Geest
Barbara Stubbe
AM JONAS
Tinneke Van Thienen
WLJ HINRICHS
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
BIOMACROMOLECULES
2006
The choice of a suitable oligosaccharide to prevent aggregation of PEGylated nanoparticles during freeze thawing and freeze drying
WLJ HINRICHS
FA MANCENIDO
Niek Sanders
Kevin Braeckmans
Stefaan De Smedt
Jo Demeester
HW FRIJLINK
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2006
The internalization route resulting in successful gene expression depends on polyethylenimine both cell line and polyplex type
K VON GERSDORFF
Niek Sanders
Roosmarijn Vandenbroucke
Stefaan De Smedt
E WAGNER
M OGRIS
A1
Journal Article
in
MOLECULAR THERAPY
2006
Ultrasound-responsive polymer-coated microbubbles that bind and protect DNA
Ine Lentacker
Bruno De Geest
Roosmarijn Vandenbroucke
Liesbeth Peeters
Jo Demeester
Stefaan De Smedt
Niek Sanders
A1
Journal Article
in
LANGMUIR
2006
2005
FRET-FCS as a tool to evaluate the stability of oligonucleotide drugs after intracellular delivery
Katrien Remaut
Bart Lucas
Kevin Braeckmans
Niek Sanders
Stefaan De Smedt
Jo Demeester
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2005
Fluorescence energy transfer to study the degradation of double-labeled oligonucleotides
Katrien Remaut
Bart Lucas
Kevin Braeckmans
Niek Sanders
Stefaan De Smedt
Jo Demeester
C3
Conference
2005
Inulin is a promising cryo- and lyoprotectant for PEGylated lipoplexes
WLJ HINRICHS
Niek Sanders
Stefaan De Smedt
Jo Demeester
HW FRIJLINK
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2005
Mobility of model proteins in hydrogels composed of oppositely charged dextran microspheres studied by protein release and fluorescence recovery after photobleaching
SR VAN TOMME
Bruno De Geest
Kevin Braeckmans
Stefaan De Smedt
F SIEPMANN
J SIEPMANN
CF VAN NOSTRUM
WE HENNINK
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2005
On the synthesis and characterization of biodegradable dextran nanogels with tunable degradation properties
Tinneke Van Thienen
Bart Lucas
FM FLESCH
CF VAN NOSTRUM
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
MACROMOLECULES
2005
Protection of oligonucleotides against nucleases by pegylated and non-pegylated liposomes as studied by fluorescence correlation spectroscopy
Katrien Remaut
Bart Lucas
Kevin Braeckmans
Niek Sanders
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2005
Self-gelling hydrogels based on oppositely charged dextran microspheres
SR VAN TOMME
MJ VAN STEENBERGEN
Stefaan De Smedt
CF VAN NOSTRUM
WE HENNINK
A1
Journal Article
in
BIOMATERIALS
2005
Self-rupturing microcapsules
Bruno De Geest
C DEJUGNAT
GB SUKHORUKOV
Kevin Braeckmans
Stefaan De Smedt
Jo Demeester
A1
Journal Article
in
ADVANCED MATERIALS
2005
Studying biophysical barriers to DNA delivery by advanced light microscopy
Stefaan De Smedt
Katrien Remaut
Bart Lucas
Kevin Braeckmans
Niek Sanders
Jo Demeester
A1
Journal Article
in
ADVANCED DRUG DELIVERY REVIEWS
2005
Studying the intracellular dissociation of polymer-oligonucleotide complexes by dual color fluorescence fluctuation spectroscopy and confocal imaging
Bart Lucas
Katrien Remaut
Niek Sanders
Kevin Braeckmans
Stefaan De Smedt
Jo Demeester
A1
Journal Article
in
BIOCHEMISTRY
2005
Synthesis of monodisperse biodegradable microgels in microfluidic devices
Bruno De Geest
JP URBANSKI
T THORSEN
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
LANGMUIR
2005
Towards a better understanding of the dissociation behavior of liposome-oligonucleotide complexes in the cytosol of cells
Bart Lucas
Katrien Remaut
Niek Sanders
Kevin Braeckmans
Stefaan De Smedt
Jo Demeester
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2005
Vitreous: a barrier to nonviral ocular gene therapy
Liesbeth Peeters
Niek Sanders
Kevin Braeckmans
Koen Boussery
Johan Van de Voorde
Stefaan De Smedt
Jo Demeester
A1
Journal Article
in
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
2005
2004
"Programmed polymeric devices" for pulsed drug delivery
Barbara Stubbe
Stefaan De Smedt
Jo Demeester
A1
Journal Article
in
PHARMACEUTICAL RESEARCH
2004
Enhancement of nuclear uptake of therapeutic genes and macromolecules by using NLS and PTD containing viral peptides
Roosmarijn Vandenbroucke
Els Vanderleyden
Stefaan De Smedt
Niek Sanders
Jo Demeester
C1
Conference
2004
Modeling the swelling pressure of degrading hydroxyethylmethacrylate-grafted dextran hydrogels
BG AMSDEN
BG STUBBE
F HORKAY
Stefaan De Smedt
Jo Demeester
A1
Journal Article
in
JOURNAL OF POLYMER SCIENCE PART B-POLYMER PHYSICS
2004
On the biological activity of anti-ICAM-1 oligonucleotides complexed to non-viral carriers
Bart Lucas
Elsa Van Rompaey
Katrien Remaut
Niek Sanders
Stefaan De Smedt
Jo Demeester
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2004
Studying pegylated DNA complexes by dual color fluorescence fluctuation spectroscopy
Bart Lucas
Katrien Remaut
Kevin Braeckmans
Jurgen Haustraete
Stefaan De Smedt
Jo Demeester
A1
Journal Article
in
MACROMOLECULES
2004
Swelling pressure of hydrogels that degrade through different mechanisms
Barbara Stubbe
WE HENNINK
Stefaan De Smedt
J DEMEESTERL
A1
Journal Article
in
MACROMOLECULES
2004
2003
Encoding microcarriers by spatial selective photobleaching
Kevin Braeckmans
Stefaan De Smedt
C ROELANT
M LEBLANS
Romain Pauwels
Jo Demeester
A1
Journal Article
in
NATURE MATERIALS
2003
Mobility and stability of gene complexes in biogels
Niek Sanders
Stefaan De Smedt
Jo Demeester
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2003
Tailoring the swelling pressure of degrading dextran hydroxyethyl methacrylate hydrogels
Barbara Stubbe
F HORKAY
B AMSDEN
WE HENNINK
Stefaan De Smedt
Jo Demeester
A1
Journal Article
in
BIOMACROMOLECULES
2003
Three-dimensional fluorescence recovery after photobleaching with the confocal scanning laser microscope
Kevin Braeckmans
Liesbeth Peeters
Niek Sanders
Stefaan De Smedt
Jo Demeester
A1
Journal Article
in
BIOPHYSICAL JOURNAL
2003
2002
A comparison between the use of dynamic mechanical analysis and oscillatory shear rheometry for the characterisation of hydrogels.
T MEYVIS
Barbara Stubbe
MJ VAN STEENBERGEN
WE HENNINK
Stefaan De Smedt
Jo Demeester
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2002
Dual-color fluorescence fluctuation spectroscopy to study the complexation between poly-l-lysine and oligonucleotides
Bart Lucas
Elsa Van Rompaey
Stefaan De Smedt
Jo Demeester
Patric Van Oostveldt
A1
Journal Article
in
MACROMOLECULES
2002
Encoding microcarriers : present and future technologies
Kevin Braeckmans
Stefaan De Smedt
Marc Leblans
Romain Pauwels
Jo Demeester
A1
Journal Article
in
NATURE REVIEWS DRUG DISCOVERY
2002
In vivo evaluation of matrix pellets containing nanocrystalline ketoprofen
Geert VERGOTE
Chris Vervaet
Isabel Van Driessche
Serge Hoste
Stefaan De Smedt
Jo Demeester
RA JAIN
S RUDDY
Jean Paul Remon
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2002
On the transport of lipoplexes through cystic fibrosis sputum.
Niek Sanders
Elsa Van Rompaey
Stefaan De Smedt
Jo Demeester
A1
Journal Article
in
PHARMACEUTICAL RESEARCH
2002
Pegylated GL67 lipoplexes retain their gene transfection activity after exposure to components of CF mucus.
Niek Sanders
Stefaan De Smedt
SH CHENG
Jo Demeester
A1
Journal Article
in
GENE THERAPY
2002
Swelling pressure observations on degrading dex-HEMA hydrogels.
Barbara Stubbe
Kevin Braeckmans
F HORKAY
WE HENNINK
Stefaan De Smedt
Jo Demeester
A1
Journal Article
in
MACROMOLECULES
2002
2001
An oral controlled release matrix pellet formulation containing nanocrystalline ketoprofen
Geert VERGOTE
Chris Vervaet
Isabel Van Driessche
Serge Hoste
Stefaan De Smedt
Jo Demeester
RA JAIN
S RUDDY
Jean Paul Remon
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2001
Biodegradable hydrogels based on stereocomplex formation between lactic acid oligomers grafted to dextran.
SJ DE JONG
Stefaan De Smedt
Jo Demeester
CF VAN NOSTRUM
JJ KETTENES-VAN DEN BOSCH
WE HENNINK
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2001
Fluorescence fluctuation analysis for the study of interactions between oligonucleotides and polycationic polymers.
Elsa Van Rompaey
Y CHEN
JD MULLER
E GRATTON
E VAN CRAENENBROECK
Y ENGELBORGHS
Stefaan De Smedt
Jo Demeester
A1
Journal Article
in
BIOLOGICAL CHEMISTRY
2001
Interactions between oligonucleotides and cationic polymers investigated by fluorescence correlation spectroscopy.
Elsa Van Rompaey
Y ENGELBORGHS
Niek Sanders
Stefaan De Smedt
Jo Demeester
A1
Journal Article
in
PHARMACEUTICAL RESEARCH
2001
On the release of proteins from degrading dextran methacrylate hydrogels and the correlation with the rheologic properties of the hydrogels.
T MEYVIS
Stefaan De Smedt
Barbara Stubbe
W HENNINK
Jo Demeester
A1
Journal Article
in
PHARMACEUTICAL RESEARCH
2001
Structural alterations of gene complexes by cystic fibrosis sputum.
Niek Sanders
Elsa Van Rompaey
Stefaan De Smedt
Jo Demeester
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2001
The in vitro evaluation of 'azo containing polysaccharide gels' for colon delivery.
Barbara Stubbe
B MARIS
G VAN DEN MOOTER
Stefaan De Smedt
Jo Demeester
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2001
2000
Cationic Polymer Based Gene Delivery Systems.
Stefaan De Smedt
Jo Demeester
WE HENNINK
A1
Journal Article
in
PHARMACEUTICAL RESEARCH
2000
Combined gelatin-chondroitin sulfate hydrogels for controlled release of cationic antibacterial proteins.
AJ KUIJPERS
GHM ENGBERS
TKL MEYVIS
Stefaan De Smedt
Jo Demeester
J KRIJGSVELD
SAJ ZAAT
J DANKERT
J FEIJEN
A1
Journal Article
in
MACROMOLECULES
2000
Complex formation between cationic polymethacrylates and oligonucleotides.
Elsa Van Rompaey
Niek Sanders
Stefaan De Smedt
Jo Demeester
E VAN CRAENENBROECK
Y ENGELBORGHS
A1
Journal Article
in
MACROMOLECULES
2000
Cystic fibrosis sputum. A barrier to the transport of nanospheres.
Niek Sanders
Stefaan De Smedt
Elsa Van Rompaey
Paul Simoens
Frans De Baets
Jo Demeester
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2000
Influence of the degradation mechanism of hydrogels on their elastic and swelling properties during degradation.
T MEYVIS
Stefaan De Smedt
Jo Demeester
WE HENNINK
A1
Journal Article
in
MACROMOLECULES
2000
Novel self-assembled hydrogels by stereocomplex formation in aqueous solution of enantiomeric lactic acid oligomers grafted to dextran.
SJ DE JONG
Stefaan De Smedt
M WAHLS
Jo Demeester
JJ KETTENES-VAN DEN BOSCH
WE HENNINK
A1
Journal Article
in
MACROMOLECULES
2000
Optimisation of an in vitro procedure for the determination of the enzymatic inhibition potency of multifunctional polymers.
Dieter Ameye
Jody Voorspoels
Jean Paul Remon
Jo Demeester
Stefaan De Smedt
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
2000
Pore sizes in hydrated dextran microspheres.
RJH STENEKES
Stefaan De Smedt
Jo Demeester
GZ SUN
ZB ZHANG
WE HENNINK
A1
Journal Article
in
BIOMACROMOLECULES
2000
The physical properties of biogels and their permeability for macromolecular drugs and colloidal drug carriers.
Niek Sanders
Stefaan De Smedt
Jo Demeester
A1
Journal Article
in
JOURNAL OF PHARMACEUTICAL SCIENCES
2000
1999
A new microphotolysis based approach for mapping the mobility of drugs in microscopic drug delivery devices
Stefaan De Smedt
Tom KL Meyvis
Patric Van Oostveldt
Jo Demeester
A1
Journal Article
in
PHARMACEUTICAL RESEARCH
1999
Characterization of the network structure of carbodiimide cross-linked gelatin gels.
AJ KUIJPERS
G ENGBERS
J FEIJEN
Stefaan De Smedt
T MEYVIS
Jo Demeester
J KRIJGSVELD
S ZAAT
J DANKERT
A1
Journal Article
in
MACROMOLECULES
1999
Fluorescence recovery after photobleaching: a versatile tool for mobility and interaction measurements in pharmaceutical research
Tom KL Meyvis
Stefaan De Smedt
Patric Van Oostveldt
Jo Demeester
A1
Journal Article
in
PHARMACEUTICAL RESEARCH
1999
Rheological monitoring of long-term degrading polymer hydrogels.
T MEYVIS
Stefaan De Smedt
Jo Demeester
WE HENNINK
A1
Journal Article
in
JOURNAL OF RHEOLOGY
1999
1998
Hyaluronan: Preparation, structure, properties, and applications.
L LAPCIK
Stefaan De Smedt
Jo Demeester
P CHABRECEK
A1
Journal Article
in
CHEMICAL REVIEWS
1998
1997
Deoxyribonuclease I
Ingrid De Meester
Stefaan De Smedt
Bookchapter
in
Pharmaceutical enzymes
1997
Diffusion of macromolecules in dextran methacrylate solutions and gels as studied by confocal scanning laser microscopy.
Stefaan De Smedt
Tom Meyvis
Jo Demeester
Patric Van Oostveldt
JCG BLONK
WE HENNINK
A1
Journal Article
in
MACROMOLECULES
1997
Moisture absorption and desorption of different rubber lyophilisation closures.
S CORVELEYN
Stefaan De Smedt
Jean Paul Remon
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
1997
1996
Controlled release of proteins from dextran hydrogels.
WE HENNINK
H TALSMA
JCH BORCHERT
Stefaan De Smedt
Jo Demeester
A1
Journal Article
in
JOURNAL OF CONTROLLED RELEASE
1996
Stabilisation of suspensions using sucrose esters and low substituted n-octenylsuccinate starch-xanthan gum associations.
JD NTAWUKULILYAYO
Stefaan De Smedt
Jo Demeester
Jean Paul Remon
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
1996
1995
A new approach in collecting diffusion data to support theological studies on gel like systems using hyaluronic acid and solutions as a model
Jo Demeester
Stefaan De Smedt
Tom Meyvis
P Van Oostveldt
C3
Conference
1995
Characterization of the network structure of dextran glycidyl methacrylate hydrogels by studying the rheological and swelling behavior
Stefaan De Smedt
Albert Lauwers
Jo Demeester
MJ Van Steenbergen
WE Hennink
SPFM Roefs
A1
Journal Article
in
MACROMOLECULES
1995
1994
Structural information on hydraulic acid solutions as studied by probe diffusion experiments.
Stefaan De Smedt
Albert Lauwers
Jo Demeester
Y ENGELBORGHS
G DEMEY
M DU
A1
Journal Article
in
MACROMOLECULES
1994
1993
Viscoelastic and transient network properties of hyaluronic acid as a function of the concentration
Stefaan De Smedt
P Dekeyser
V Ribitsch
Albert Lauwers
Jo Demeester
A1
Journal Article
in
BIORHEOLOGY
1993
1992
High Pressure, size-exclusion chromatography of Proteoglycans extracted from Bovine Articular Cartilage.
Philippe Dekeyser
Stefaan De Smedt
Koen Vercruysse
Jo Demeester
Albert Lauwers
C1
Conference
1992
Structural Rheology of Biopolymers
Stefaan De Smedt
Philippe Dekeyser
Koen Vercruysse
Jo Demeester
C1
Conference
1992
Structural Rheology of Hyaluronic Acid
Stefaan De Smedt
Jo Demeester
C1
Conference
1992
Viscoölastic Properties of Hyaluronic Acid Solutions as a Function of Concentration
Stefaan De Smedt
Albert Lauwers
Jo Demeester
C1
Conference
1992
Hyaluronidase Action on Hyaluronic Acid monitored by G.P.C. Abstract Intern. Conference of Enzymatic Synthesis and Modification of Carbohydrates, Coventry, U.K., 1992.
Koen Vercruysse
Philippe Dekeyser
Stefaan De Smedt
Albert Lauwers
J DE MEESTER
C1
Conference
Hyaluronidase action of hyaluronic acid monitored by G.P.C. Abstract of the Intern. Conference of Enzymatic Synthesis and Modification of Carbohydrates, Coventry, U.K., juli, 1992.
K VERCRUYSSE
P DEKEYSER
Stefaan De Smedt
A LAUWERS
J DE MEESTER
C1
Conference
