Research Explorer

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Researcher

Sofie Vandevyver

Awards & Distinctions

17 Results

2020

Zinc inhibits lethal inflammatory shock by preventing microbe-induced interferon signature in intestinal epithelium

Jolien SouffriauSteven TimmermansTineke VanderhaeghenCharlotte WallaeysKelly Van LooverenLindsy AelbrechtSylviane DewaeleJolien VandewalleEvy GoossensSerge Verbanck et al.

A1 Journal Article in EMBO MOLECULAR MEDICINE

2019

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile

Karen DendonckerSteven TimmermansJolien VandewalleMelanie EggermontJoanna LempiäinenVille PaakinahoEvelien Van HammeSylviane DewaeleSofie VandevyverMarlies Ballegeer et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

2018

Glucocorticoid receptor dimers control intestinal STAT1 and TNF-induced inflammation in mice

Marlies BallegeerKelly Van LooverenSteven TimmermansMelanie EggermontSofie VandevyverFabien Henri TheryKaren DendonckerJolien SouffriauJolien VandewalleLise Van Wyngene et al.

A1 Journal Article in JOURNAL OF CLINICAL INVESTIGATION

2017

Glucocorticoid receptor-mediated transactivation is hampered by Striatin-3, a novel interaction partner of the receptor

Ioanna PettaNadia BougarneJolien VandewalleLien DejagerSofie VandevyverMarlies BallegeerSofie DesmetJonathan ThommisLode De CauwerSam Lievens et al.

A1 Journal Article in SCIENTIFIC REPORTS

2015

Glucocorticoid-induced microRNA-511 protects against TNF by down-regulating TNFR1

Leen PuimègeFilip Van HauwermeirenSophie SteelandSara Van RyckeghemJolien VandewalleSofie LodensLien DejagerSofie VandevyverJan StaelensSteven Timmermans et al.

A1 Journal Article in EMBO MOLECULAR MEDICINE

Neutralizing TNFα restores glucocorticoid sensitivity in a mouse model of neutrophilic airway inflammation

Lien DejagerKaren DendonckerMelanie EggermontJolien SouffriauFilip Van HauwermeirenMonique WillartElien Van WonterghemThomas NaessensMarlies BallegeerSofie Vandevyver et al.

A1 Journal Article in MUCOSAL IMMUNOLOGY

2014

An acute phase protein ready to go therapeutic for sepsis

Sofie VandevyverLien DejagerRoosmarijn VandenbrouckeClaude Libert

Editorial material

Comprehensive overview of the structure and regulation of the glucocorticoid receptor

Sofie VandevyverLien DejagerClaude Libert

A1 Journal Article in ENDOCRINE REVIEWS

Dominance of the strongest: inflammatory cytokines versus glucocorticoids

Lien DejagerSofie VandevyverIoanna PettaClaude Libert

A1 Journal Article in CYTOKINE & GROWTH FACTOR REVIEWS

Pharmacological inhibition of type I interferon signaling protects mice against lethal sepsis

Lien DejagerSofie VandevyverMarlies BallegeerElien Van WonterghemLing-Ling AnJeffrey RiggsRoland KolbeckClaude Libert

A1 Journal Article in JOURNAL OF INFECTIOUS DISEASES

2013

LPS resistance of SPRET/Ei mice is mediated by Gilz, encoded by the Tsc22d3 gene on the X chromosome

Iris PinheiroLien DejagerIoanna PettaSofie VandevyverLeen PuimègeTina MahieuMarlies BallegeerFilip Van HauwermeirenCarlo RiccardiMarnik Vuylsteke et al.

A1 Journal Article in EMBO MOLECULAR MEDICINE

New insights into the anti-inflammatory mechanisms of glucocorticoids : an emerging role for glucocorticoid-receptor-mediated transactivation

Sofie VandevyverLien DejagerJan TuckermannClaude Libert

A1 Journal Article in ENDOCRINOLOGY

Study of the molecular mechanisms of glucocorticoid receptor function and resistance in TNF-induced toxicity

Sofie VandevyverClaude Libert

2012

Glucocorticoid receptor dimerization induces MKP1 to protect against TNF-induced inflammation

Sofie VandevyverLien DejagerTom Van BogaertAnna KleymanYusen LiuJan TuckermannClaude Libert

A1 Journal Article in JOURNAL OF CLINICAL INVESTIGATION

On the trail of the glucocorticoid receptor: into the nucleus and back

Sofie VandevyverLien DejagerClaude Libert

A1 Journal Article in TRAFFIC

2011

Strategies to inhibit the toxicity of systemic TNF treatment

Filip Van HauwermeirenLeen PuimègeSofie VandevyverTom Van BogaertIneke VanlaereLiesbeth HuysLien DejagerClaude Libert

A1 Journal Article in Advances in Experimental Medicine and Biology

Tumor necrosis factor Inhibits glucocorticoid receptor function in mice a strong signal toward lethal shock

Tom Van BogaertSofie VandevyverLien DejagerFilip Van HauwermeirenIris PinheiroIoanna PettaDavid EngblomAnna KleymanGuenther SchutzJan Tuckermann et al.

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY