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Researcher
Séverine Mortier
Profile
Projects
Publications
Activities
Awards & Distinctions
58
Results
2020
A generic reverse osmosis model for full-scale operation
Dorien Gaublomme
Laurence Strubbe
Marjolein Vanoppen
Elena Torfs
Séverine Mortier
Emile Cornelissen
Bart De Gusseme
Arne Verliefde
Ingmar Nopens
A1
Journal Article
in
DESALINATION
2020
2019
Validation of a generic steady state model for full-scale Reverse Osmosis
Dorien Gaublomme
Marjolein Vanoppen
Laurence Strubbe
Bart De Gusseme
Séverine Mortier
Emile Cornelissen
Arne Verliefde
Ingmar Nopens
C3
Conference
2019
Validation of a generic steady state model for full-scale reverse osmosis
Dorien Gaublomme
Marjolein Vanoppen
Laurence Strubbe
Bart De Gusseme
Séverine Mortier
Emile Cornelissen
Arne Verliefde
Ingmar Nopens
C1
Conference
2019
2018
Developing a framework to model the primary drying step of a continuous freeze-drying process based on infrared radiation
Pieter-Jan Van Bockstal
Jos Corver
Séverine Mortier
Laurens De Meyer
Ingmar Nopens
Krist V Gernaey
Thomas De Beer
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
2018
Dynamic validation of online applied and surrogate-based models for tertiary ozonation on pilot-scale
Michael Chys
Wim Audenaert
Jan Vangrinsven
Michael Bauwens
Séverine Mortier
Herman Van Langenhove
Ingmar Nopens
Kristof Demeestere
Stijn Van Hulle
A1
Journal Article
in
CHEMOSPHERE
2018
Global Sensitivity Analysis as Good Modelling Practices tool for the identification of the most influential process parameters of the primary drying step during freeze-drying
Pieter-Jan Van Bockstal
Séverine Mortier
Jos Corver
Ingmar Nopens
Krist V Gernaey
Thomas De Beer
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
2018
Model calibration and validation of a full-scale reverse osmosis process
Dorien Gaublomme
Marjolein Vanoppen
Bart De Gusseme
Séverine Mortier
Arne Verliefde
Ingmar Nopens
C3
Conference
2018
Potential of near-infrared chemical imaging as process analytical technology tool for continuous freeze-drying
Davinia Brouckaert
Laurens De Meyer
Brecht Vanbillemont
Pieter-Jan Van Bockstal
Joris Lammens
Séverine Mortier
Jos Corver
Chris Vervaet
Ingmar Nopens
Thomas De Beer
A1
Journal Article
in
ANALYTICAL CHEMISTRY
2018
The relevance of shear, sedimentation and diffusion during spin freezing, as potential first step of a continuous freeze-drying process for unit doses
Joris Lammens
Séverine Mortier
Laurens De Meyer
Brecht Vanbillemont
Pieter-Jan Van Bockstal
Simon Van Herck
Jos Corver
Ingmar Nopens
Valérie Vanhoorne
Bruno De Geest
et al.
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2018
2017
Extension of a mechanistic model for drying of single pharmaceutical granules to semi-continuous fluid bed drying
Michael Ghijs
Séverine Mortier
Philippe Cappuyns
Krist V Gernaey
Thomas De Beer
Ingmar Nopens
C3
Conference
2017
In-depth experimental analysis of pharmaceutical twin-screw wet granulation in view of detailed process understanding
Maxim Verstraeten
Daan Van Hauwermeiren
Kai Lee
Neil Turnbull
David Wilsdon
Mary Am Ende
Pankaj Doshi
Chris Vervaet
Davinia Brouckaert
Séverine Mortier
et al.
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2017
Mechanistic modelling of infrared mediated energy transfer during the primary drying step of a continuous freeze-drying process
Pieter-Jan Van Bockstal
Séverine Mortier
Laurens De Meyer
Jos Corver
Chris Vervaet
Ingmar Nopens
Thomas De Beer
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
2017
Modelling the primary drying step for the determination of the optimal dynamic heating pad temperature in a continuous pharmaceutical freeze-drying process for unit doses
Laurens De Meyer
Joris Lammens
Séverine Mortier
Brecht Vanbillemont
Pieter-Jan Van Bockstal
Jos Corver
Ingmar Nopens
Chris Vervaet
Thomas De Beer
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2017
Practical implementation of dynamic primary drying settings in a continuous freeze-drying process
Brecht Vanbillemont
Niels Nicolaï
Pieter-Jan Van Bockstal
Laurens De Meyer
Séverine Mortier
Jos Corver
Chris Vervaet
Thomas De Beer
C3
Conference
2017
Quantitative risk assessment via uncertainty analysis in combination with error propagation for the determination of the dynamic Design Space of the primary drying step during freeze-drying
Pieter-Jan Van Bockstal
Séverine Mortier
Jos Corver
Ingmar Nopens
Krist V Gernaey
Thomas De Beer
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
2017
Surrogate-based correlation models in view of real-time control of ozonation of secondary treated municipal wastewater-model development and dynamic validation
Michael Chys
Wim Audenaert
Emma Deniere
Séverine Mortier
Herman Van Langenhove
Ingmar Nopens
Kristof Demeestere
Stijn Van Hulle
A1
Journal Article
in
ENVIRONMENTAL SCIENCE & TECHNOLOGY
2017
Towards advanced aeration modelling : from blower to bubbles to bulk
Andreia Neves do Amaral
Oliver Schraa
Leiv Rieger
Sylvie Gillot
Yannick Fayolle
Giacomo Bellandi
Youri Amerlinck
Séverine Mortier
Riccardo Gori
Ramiro Neves
et al.
A1
Journal Article
in
WATER SCIENCE AND TECHNOLOGY
2017
2016
A dynamic design space for primary drying during batch freeze-drying
Séverine Mortier
Pieter-Jan Van Bockstal
Ingmar Nopens
Thomas De Beer
Krist V Gernaey
A1
Journal Article
in
CHIMICA OGGI-CHEMISTRY TODAY
2016
Model-based analysis of a twin-screw wet granulation system for continuous solid dosage manufacturing
Ashish Kumar
Jurgen Vercruysse
Séverine Mortier
Chris Vervaet
Jean Paul Remon
Krist V Gernaey
Thomas De Beer
Ingmar Nopens
A1
Journal Article
in
COMPUTERS & CHEMICAL ENGINEERING
2016
Model-based process analysis in continuous manufacturing of pharmaceuticals : calibration of a fluid bed dryer model
Michael Ghijs
Fien De Leersnyder
Daan Van Hauwermeiren
Valérie Vanhoorne
Jurgen Vercruysse
Philippe Cappuyns
Séverine Mortier
Thomas De Beer
Krist Gernaey
Ingmar Nopens
C3
Conference
2016
Modelling and sensitivity analysis of urinary platinum excretion in anticancer chemotherapy for the recovery of platinum
Karel Folens
Séverine Mortier
Janis Baeten
KAREN COUVREUR
Robin Michelet
Krist V Gernaey
Thomas De Beer
Gijs Du Laing
Ingmar Nopens
A1
Journal Article
in
SUSTAINABLE CHEMISTRY AND PHARMACY
2016
The use of rheology combined with differential scanning calorimetry to elucidate the granulation mechanism of an immiscible formulation during continuous twin-screw melt granulation
Tinne Monteyne
Liza Heeze
Séverine Mortier
Klaus Oldörp
Ruth Cardinaels
Ingmar Nopens
Chris Vervaet
Jean Paul Remon
Thomas De Beer
A1
Journal Article
in
PHARMACEUTICAL RESEARCH
2016
The use of rheology to elucidate the granulation mechanisms of a miscible and immiscible system during continuous twin-screw melt granulation
Tinne Monteyne
Liza Heeze
Séverine Mortier
Klaus Oldörp
Ingmar Nopens
Jean Paul Remon
Chris Vervaet
Thomas De Beer
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2016
Towards advanced aeration modelling: from blower to bubbles to bulk
Andreia Neves do Amaral
Oliver Schraa
Leiv Reiger
Sylvie Gillot
Yannick Fayolle
Giacomo Bellandi
Youri Amerlinck
Séverine Mortier
Riccardo Gori
Ramiro Neves
et al.
C1
Conference
2016
Uncertainty analysis as essential step in the establishment of the dynamic Design Space of primary drying during freeze-drying
Séverine Mortier
Pieter-Jan Van Bockstal
Jos Corver
Ingmar Nopens
Krist V Gernaey
Thomas De Beer
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
2016
2015
Gaining process knowledge by using mechanistic models for fluidized bed drying in a continuous manufacturing environment
Séverine Mortier
Ingmar Nopens
Krist V Gernaey
Thomas De Beer
C3
Conference
2015
Model-based optimization of the primary drying step during freeze-drying
Séverine Mortier
Pieter-Jan Van Bockstal
Ingmar Nopens
Krist V Gernaey
Thomas De Beer
P1
Conference
2015
Model-based optimization of the primary drying step during freeze-drying
Séverine Mortier
Krist V Gernaey
Ingmar Nopens
Pieter-Jan Van Bockstal
Thomas De Beer
C3
Conference
2015
Towards improved accuracy in modelling aeration efficiency by accounting for bubble size distribution dynamics
Andreia Neves do Amaral
Giacomo Bellandi
Youri Amerlinck
Séverine Mortier
Ramiro Neves
Ingmar Nopens
C1
Conference
2015
2014
A two-dimensional PBM for continuous drying of a population of granules including drying and breakage
Séverine Mortier
Krist V Gernaey
Thomas De Beer
Ingmar Nopens
C3
Conference
2014
Analysing drying unit performance in a continuous pharmaceutical manufacturing line by means of mass-energy balances
Séverine Mortier
Krist V Gernaey
Thomas De Beer
Ingmar Nopens
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
2014
Applying reconstruction methods on the solution of a moment-based pharmaceutical drying process Population Balance Model
Séverine Mortier
Krist V Gernaey
Thomas De Beer
Ingmar Nopens
C3
Conference
2014
Comparison of techniques for reconstruction of a distribution from moments in the context of a pharmaceutical drying process
Séverine Mortier
Thomas De Beer
Krist V Gernaey
Ingmar Nopens
A1
Journal Article
in
COMPUTERS & CHEMICAL ENGINEERING
2014
Global sensitivity analysis applied to drying models for one or a population of granules
Séverine Mortier
Krist V Gernaey
Thomas De Beer
Ingmar Nopens
A1
Journal Article
in
AICHE JOURNAL
2014
Mechanistic modelling for process understanding of fluidized bed drying process part of a full continuous pharmaceutical manufacturing line
Séverine Mortier
Thomas De Beer
Krist V Gernaey
Ingmar Nopens
C3
Conference
2014
Modelling the drying behaviour of wet granules in the context of fully continuous pharmaceutical tablet manufacturing
Séverine Mortier
Ingmar Nopens
Thomas De Beer
Krist V Genaey
Dissertation
2014
Moisture and drug solid-state monitoring during a continuous drying process using empirical and mass balance models
Margot Fonteyne
Delphine Gildemyn
Elisabeth Peeters
Séverine Mortier
Jurgen Vercruysse
Krist V Gernaey
Chris Vervaet
Jean Paul Remon
Ingmar Nopens
Thomas De Beer
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
2014
Monitoring and modelling of a continuous from-powder-to-tablet process line
Séverine Mortier
Ingmar Nopens
Thomas De Beer
Krist V Gernaey
A1
Journal Article
in
CHIMICA OGGI-CHEMISTRY TODAY
2014
Process monitoring and modeling of a continuous pharmaceutical from powder to tablet process line using a mass and energy balance
Séverine Mortier
Thomas De Beer
Ingmar Nopens
Krist V Gernaey
C3
Conference
2014
Two-dimensional PBM for simultaneous modelling of drying and breakage of pharmaceutical granules
Séverine Mortier
Ingmar Nopens
Krist V Gernaey
Thomas De Beer
C3
Conference
2014
2013
A GLUE uncertainty analysis of a drying model of pharmaceutical granules
Séverine Mortier
Stijn Van Hoey
Katrijn Cierkens
Krist V Gernaey
Piet Seuntjens
Bernard De Baets
Thomas De Beer
Ingmar Nopens
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
2013
Design, synthesis and structure-activity relationships of some novel, highly potent anti-invasive (E)- and (Z)-stilbenes
Bart Roman
Laurens De Coen
Séverine Mortier
Tine De Ryck
Barbara Vanhoecke
Alan R Katritzky
Marc Bracke
Christian Stevens
A1
Journal Article
in
BIOORGANIC & MEDICINAL CHEMISTRY
2013
Development of a population balance model of a pharmaceutical drying process and testing of solution methods
Séverine Mortier
Krist Gernaey
Thomas De Beer
Ingmar Nopens
A1
Journal Article
in
COMPUTERS & CHEMICAL ENGINEERING
2013
Global sensitivity analysis on a PBM-model describing the drying behaviour of wet pharmaceutical granules
Séverine Mortier
Krist V Gernaey
Thomas De Beer
Ingmar Nopens
C1
Conference
2013
Process monitoring for the continuous tabletting line ConsiGma using in-line measurements
Séverine Mortier
KV Gernaey
Thomas De Beer
Ingmar Nopens
C3
Conference
2013
Process monitoring of a full continuous pharmaceutical tabletting line : mass and energy balance analysis
Séverine Mortier
Ingmar Nopens
Thomas De Beer
Krist V Gernaey
C3
Conference
2013
Reduction of a single granule drying model: an essential step in preparation of a population balance model with a continuous growth term
Séverine Mortier
Timothy Van Daele
Krist V Gernaey
Thomas De Beer
Ingmar Nopens
A1
Journal Article
in
AICHE JOURNAL
2013
Scenario analysis on a PBM describing the drying behaviour of wet pharmaceutical granules
Séverine Mortier
Krist V Gernaey
Thomas De Beer
Ingmar Nopens
C1
Conference
2013
The use of mass and energy balances for process monitoring of a full continuous pharmaceutical from powder to tablet manufacturing
Séverine Mortier
Ingmar Nopens
Thomas De Beer
Krist V Gernaey
C3
Conference
2013
Using a PBM to describe the drying behaviour of wet pharmaceutical granules : scenario analysis and GSA
Séverine Mortier
Ingmar Nopens
Thomas De Beer
Krist V Gernaey
C3
Conference
2013
2012
Application of global sensitivity analysis as preparatory step for reduction of a drying model of pharmaceutical granules
Séverine Mortier
Ingmar Nopens
Thomas De Beer
Krist Gernaey
C3
Conference
2012
Application of model uncertainty analysis on the modelling of the drying behaviour of single pharmaceutical granules
Séverine Mortier
Stijn Van Hoey
Katrijn Cierkens
Thomas De Beer
Kris Gernaey
Ingmar Nopens
C3
Conference
2012
Application of model uncertainty analysis on the modelling of the drying behaviour of single pharmaceutical granules
Séverine Mortier
Stijn Van Hoey
Katrijn Cierkens
Thomas De Beer
Kris V Gernaey
Ingmar Nopens
C3
Conference
2012
Mechanistic modelling of the drying behaviour of single pharmaceutical granules
Séverine Mortier
Thomas De Beer
Krist Gernaey
Jurgen Vercruysse
Margot Fonteyne
Jean Paul Remon
Chris Vervaet
Ingmar Nopens
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
2012
Uncertainty analysis applied on drying model for pharmaceutical granules
Séverine Mortier
Stijn Van Hoey
Katrijn Cierkens
Thomas De Beer
Krist V Gernaey
Ingmar Nopens
C3
Conference
2012
2011
Mechanistic modelling of fluidized bed drying processes of wet porous granules: a review
Séverine Mortier
Thomas De Beer
Krist V Gernaey
Jean Paul Remon
Chris Vervaet
Ingmar Nopens
A1
Journal Article
in
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
2011
Modelling of drying processes of pharmaceutical granules
Séverine Mortier
Sreepriya Vedantam
Thomas De Beer
KV Gernaey
Jean Paul Remon
Chris Vervaet
Ingmar Nopens
C3
Conference
2011
Modelling of drying processes of pharmaceutical granules
Séverine Mortier
Sreepriya Vedantam
Thomas De Beer
KV Gernaey
Margot Fonteyne
Jurgen Vercruysse
Jean Paul Remon
Chris Vervaet
Ingmar Nopens
C3
Conference
2011