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Researcher
Sander Lefere
Profile
Projects
Publications
Activities
Awards & Distinctions
51
Results
2023
Bariatric surgery for NAFLD : indications and post-operative management
Anja Geerts
Sander Lefere
A1
Journal Article
in
CLINICAL AND MOLECULAR HEPATOLOGY
2023
Kupffer cells contested as early drivers in the pathogenesis of primary sclerosing cholangitis
Kevin De Muynck
Bart Vanderborght
Federico Francesco De Ponti
Eva Gijbels
Sophie Van Welden
Martin Guilliams
Charlotte Scott
Alain Beschin
Mathieu Vinken
Sander Lefere
et al.
A1
Journal Article
in
AMERICAN JOURNAL OF PATHOLOGY
2023
Meta-analysis : the impact of light-to-moderate alcohol consumption on progressive non-alcoholic fatty liver disease
Louise Magherman
Robbe Van Parys
Nele Pauwels
Xavier Verhelst
Lindsey Devisscher
Hans Van Vlierberghe
Anja Geerts
Sander Lefere
A1
Journal Article
in
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
2023
Reply
Sander Lefere
Anja Geerts
Ruth De Bruyne
A1
Journal Article
in
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
2023
‘A radical operation’ : a thematic analysis of newspaper framing of bariatric surgery in adolescents
Sander Lefere
Kato Verghote
Ruth De Bruyne
Veerle Provoost
Priya Pramod Satalkar
A1
Journal Article
in
BMC PUBLIC HEALTH
2023
2022
A mouse model of hepatic encephalopathy : bile duct ligation induces brain ammonia overload, glial cell activation and neuroinflammation.
Wouter Claeys
Lien Van Hoecke
Anja Geerts
Hans Van Vlierberghe
Sander Lefere
Griet Van Imschoot
Elien Van Wonterghem
Bart Ghesquière
Roosmarijn Vandenbroucke
Christophe Van Steenkiste
A1
Journal Article
in
SCIENTIFIC REPORTS
2022
Adipose tissue insulin resistance is a determinant of disease severity in pediatric nonalcoholic fatty liver disease
Anneleen Heldens
Ellen Dupont
Lindsey Devisscher
Anja Geerts
Ruth De Bruyne
Xavier Verhelst
Hans Van Vlierberghe
Sander Lefere
C3
Conference
2022
Combined therapy with a CCR2/CCR5 antagonist and FGF21 analogue synergizes in ameliorating steatohepatitis and fibrosis
Tobias Puengel
Sander Lefere
Jana Hundertmark
Marlene Kohlhepp
Christian Penners
Frederique Van de Velde
Bruno Lapauw
Anne Hoorens
Lindsey Devisscher
Anja Geerts
et al.
A1
Journal Article
in
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2022
Glycomics-based serum marker as reliable tool for assessment of viral response after treatment with direct-acting antiviral drugs in hepatitis C virus infection
Nicky Somers
Elisabeth Vandekerckhove
Anja Geerts
Helena Degroote
Sander Lefere
Lindsey Devisscher
Leander Meuris
Nico Callewaert
Hans Van Vlierberghe
Xavier Verhelst
C3
Conference
2022
Intensive lifestyle management improves steatosis and fibrosis in pediatric non-alcoholic fatty liver disease
Sander Lefere
Ellen Dupont
Ann De Guchtenaere
Stephanie Van Biervliet
Saskia Vande Velde
Xavier Verhelst
Lindsey Devisscher
Hans Van Vlierberghe
Anja Geerts
Ruth De Bruyne
A1
Journal Article
in
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
2022
MD2 AMP(K)s up the link between lipid accumulation and inflammation in NAFLD COMMENT
Anneleen Heldens
Sander Lefere
Editorial material
2022
Maternal and perinatal risk factors for pediatric nonalcoholic fatty liver disease : a systematic review
Ilya Querter
Nele Pauwels
Ruth De Bruyne
Ellen Dupont
Xavier Verhelst
Lindsey Devisscher
Hans Van Vlierberghe
Anja Geerts
Sander Lefere
A1
Journal Article
in
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
2022
Metallothioneins alter macrophage phenotype and represent novel therapeutic targets for acetaminophen-induced liver injury
Lindsey Devisscher
Sanne Van Campenhout
Sander Lefere
Sarah Raevens
Laurentijn Tilleman
Filip Van Nieuwerburgh
Hannelore P. Van Eeckhoutte
Anne Hoorens
Michael A. Lynes
Anja Geerts
et al.
A1
Journal Article
in
JOURNAL OF LEUKOCYTE BIOLOGY
2022
Neurometabolic and gliovascular changes in murine hepatic encephalopathy
Wouter Claeys
Lien Van Hoecke
Anja Geerts
Hans Van Vlierberghe
Xavier Verhelst
Sander Lefere
Helena Degroote
Griet Van Imschoot
Elien Van Wonterghem
Roosmarijn Vandenbroucke
et al.
C3
Conference
2022
Perinatal risk factors for pediatric nonalcoholic fatty liver disease : impact of inborn errors of metabolism : reply
Ilya Querter
Ruth De Bruyne
Anja Geerts
Sander Lefere
A1
Journal Article
in
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
2022
2021
Bariatric surgery and the liver : mechanisms, benefits, and risks
Sander Lefere
Louis Onghena
Aude Vanlander
Yves Van Nieuwenhove
Lindsey Devisscher
Anja Geerts
A1
Journal Article
in
OBESITY REVIEWS
2021
Characterization of the inflammatory microenvironment and hepatic macrophage subsets in experimental hepatocellular carcinoma models
Helena Degroote
Sander Lefere
Astrid Vandierendonck
Bart Vanderborght
Tim Meese
Filip Van Nieuwerburgh
Xavier Verhelst
Anja Geerts
Hans Van Vlierberghe
Lindsey Devisscher
A2
Journal Article
in
ONCOTARGET
2021
Intensive lifestyle management improves steatosis and fibrosis in pediatric metabolic-associated fatty liver disease
Sander Lefere
Ellen Dupont
Ann De Guchtenaere
Stephanie Van Biervliet
Saskia Vande Velde
Xavier Verhelst
Lindsey Devisscher
Hans Van Vlierberghe
Anja Geerts
Ruth De Bruyne
C3
Conference
2021
The neurogliovascular unit in hepatic encephalopathy
Wouter Claeys
Lien Van Hoecke
Sander Lefere
Anja Geerts
Xavier Verhelst
Hans Van Vlierberghe
Helena Degroote
Lindsey Devisscher
Roosmarijn Vandenbroucke
Christophe Van Steenkiste
A1
Journal Article
in
JHEP REPORTS
2021
2020
A murine model of hepatic encephalopathy : validation and neurobehavioral testing
Wouter Claeys
Anja Geerts
Sander Lefere
Hans Van Vlierberghe
Griet Van Imschoot
Elien Van Wonterghem
Roosmarijn Vandenbroucke
Christophe Van Steenkiste
C3
Conference
2020
Angiogenesis in the progression of non-alcoholic fatty liver disease
Sander Lefere
Lindsey Devisscher
Anja Geerts
A1
Journal Article
in
ACTA GASTRO-ENTEROLOGICA BELGICA
2020
Bariatric surgery patients are at risk for alcoholic liver disease with need for liver transplantation
Sander Lefere
Lenka Stroobant
Xavier Verhelst
Aude Vanlander
Frederik Berrevoet
Roberto Troisi
Yves Van Nieuwenhove
Xavier Rogiers
Hans Van Vlierberghe
Anja Geerts
A1
Journal Article
in
OBESITY SURGERY
2020
Combination of sivelestat and N-acetylcysteine alleviates the inflammatory response and exceeds standard treatment for acetaminophen-induced liver injury
Sarah Raevens
Sanne Van Campenhout
Pieter-Jan Debacker
Sander Lefere
Xavier Verhelst
Anja Geerts
Hans Van Vlierberghe
Isabelle Colle
Lindsey Devisscher
A1
Journal Article
in
JOURNAL OF LEUKOCYTE BIOLOGY
2020
Differential effects of selective- and pan-PPAR agonists on experimental steatohepatitis and hepatic macrophages
Sander Lefere
Tobias Puengel
Jana Hundertmark
Christian Penners
Anna Katharina Frank
Adrien Guillot
Kevin De Muynck
Felix Heymann
Vanessa Adarbes
Evelyne Defrene
et al.
A1
Journal Article
in
JOURNAL OF HEPATOLOGY
2020
Effect of isoform-specific HIF-1α and HIF-2α antisense oligonucleotides on tumorigenesis, inflammation and fibrosis in a hepatocellular carcinoma mouse model
Bart Vanderborght
Kevin De Muynck
Sander Lefere
Anja Geerts
Helena Degroote
Xavier Verhelst
Hans Van Vlierberghe
Lindsey Devisscher
A2
Journal Article
in
ONCOTARGET
2020
Lighter serum copper isotopic composition in patients with early non-alcoholic fatty liver disease
Sanne Van Campenhout
Agustina Ari Murti Budi Hastuti
Sander Lefere
Hans Van Vlierberghe
Frank Vanhaecke
Marta Costas Rodriguez
Lindsey Devisscher
A2
Journal Article
in
BMC RESEARCH NOTES
2020
Myeloid IRE1a deletion alters hepatic macrophage phenotype and attenuates experimental non-alcoholic steatohepatitis-related hepatocellular carcinoma
Sanne Van Campenhout
Laurentijn Tilleman
Sander Lefere
Astrid Vandierendonck
Anja Geerts
Xavier Verhelst
Filip Van Nieuwerburgh
Hans Van Vlierberghe
Lindsey Devisscher
C3
Conference
2020
Myeloid-specific IRE1alpha deletion reduces tumour development in a diabetic, non-alcoholic steatohepatitis-induced hepatocellular carcinoma mouse model
Sanne Van Campenhout
Laurentijn Tilleman
Sander Lefere
Aster Vandierendonck
Sarah Raevens
Xavier Verhelst
Anja Geerts
Filip Van Nieuwerburgh
Hans Van Vlierberghe
Lindsey Devisscher
A1
Journal Article
in
METABOLISM-CLINICAL AND EXPERIMENTAL
2020
Targeting CCR2/5 in the treatment of nonalcoholic steatohepatitis (NASH) and fibrosis : opportunities and challenges
Sander Lefere
Lindsey Devisscher
Frank Tacke
Editorial material
2020
The angiopoietin/tie2 pathway in hepatocellular carcinoma
Bart Vanderborght
Sander Lefere
Hans Van Vlierberghe
Lindsey Devisscher
A1
Journal Article
in
CELLS
2020
2019
Angiogenesis and macrophages as diagnostic and therapeutic targets in non-alcoholic fatty liver disease
Sander Lefere
Anja Geerts
Lindsey Devisscher
Christophe Van Steenkiste
Dissertation
2019
Angiopoietin-2 promotes pathological angiogenesis and is a therapeutic target in murine nonalcoholic fatty liver disease
Sander Lefere
Frederique Van de Velde
Anne Hoorens
Sarah Raevens
Sanne Van Campenhout
Aster Vandierendonck
Sara Neyt
Bert Vandeghinste
Christian Vanhove
Charlotte Debbaut
et al.
A1
Journal Article
in
HEPATOLOGY
2019
Macrophages in obesity and non-alcoholic fatty liver disease : crosstalk with metabolism
Sander Lefere
Frank Tacke
A1
Journal Article
in
JHEP REPORTS
2019
Myeloid-specific IRE1 alpha deletion reduces tumour development in a non-alcoholic steatohepatitis-induced hepatocellular carcinoma mouse model
Sanne Van Campenhout
Sander Lefere
Aster Vandierendonck
Xavier Verhelst
Anja Geerts
Hans Van Vlierberghe
Lindsey Devisscher
C3
Conference
2019
Unveiling the depletion of Kupffer cells in experimental hepatocarcinogenesis through liver macrophage subtype-specific markers
Sander Lefere
Helena Degroote
Hans Van Vlierberghe
Lindsey Devisscher
A1
Journal Article
in
JOURNAL OF HEPATOLOGY
2019
2018
Angiopoietin-2 as therapeutic target for pathological angiogenesis and inflammation in non-alcoholic steatohepatitis
Sander Lefere
F Van de Velde
Sarah Raevens
Sanne Van Campenhout
Aster Vandierendonck
Sara Neyt
Christian Vanhove
Anne Hoorens
CHRISTINE CASTELEYN
Xavier Verhelst
et al.
C3
Conference
2018
Angiopoietin-2 as therapeutic target for pathological angiogenesis and inflammation in non-alcoholic steatohepatitis
Sander Lefere
Frederique Van de Velde
Sarah Raevens
Sanne Van Campenhout
Aster Vandierendonck
S Neyt
Christian Vanhove
Anne Hoorens
Christophe Casteleyn
Xavier Verhelst
et al.
C3
Conference
2018
Angiopoietin-2 promotes pathological angiogenesis and is a novel therapeutic target in non-alcoholic fatty liver disease
Sander Lefere
Frederique Van de Velde
Anne Hoorens
Sarah Raevens
Sanne Van Campenhout
Aster Vandierendonck
Sara Neyt
Bert Vandeghinste
Christian Vanhove
Charlotte Debbaut
et al.
C3
Conference
2018
Placental growth factor inhibition targets pulmonary angiogenesis and represents a therapy for hepatopulmonary syndrome in mice
Sarah Raevens
Anja Geerts
Annelies Paridaens
Sander Lefere
Xavier Verhelst
Anne Hoorens
Jo Van Dorpe
Tania Maes
Ken Bracke
Christophe Casteleyn
et al.
A1
Journal Article
in
HEPATOLOGY
2018
The combination of N-acetylcysteine and anti-MT antibodies as novel therapy for acetaminophen-induced liver injury
Lindsey Devisscher
Debby Laukens
Hannelore Van Eeckhoutte
Sarah Raevens
Sander Lefere
Anne Hoorens
Xavier Verhelst
M Lynes
Anja Geerts
Hans Van Vlierberghe
C3
Conference
2018
2017
Anti-placental growth factor therapy attenuates experimental hepatopulmonary syndrome
Sarah Raevens
Annelies Paridaens
Sander Lefere
Christophe Casteleyn
B Jonckx
Xavier Verhelst
Hans Van Vlierberghe
Christophe Van Steenkiste
Anja Geerts
Lindsey Devisscher
et al.
C3
Conference
2017
Kupffer cell pool is maintained by local proliferation and the differentiation of bone marrow monocytes into short-lived monocyte-derived Kupffer cells during non-alcoholic steatohepatitis and recovery
Lindsey Devisscher
Charlotte Scott
Sander Lefere
Sarah Raevens
Eliene Bogaerts
Annelies Paridaens
Xavier Verhelst
Anja Geerts
Martin Guilliams
Hans Van Vlierberghe
C3
Conference
2017
Non-alcoholic steatohepatitis induces transient changes within the liver macrophage pool
Lindsey Devisscher
Charlotte Scott
Sander Lefere
Sarah Raevens
Eliene Bogaerts
Annelies Paridaens
Xavier Verhelst
Anja Geerts
Martin Guilliams
Hans Van Vlierberghe
A1
Journal Article
in
CELLULAR IMMUNOLOGY
2017
Refractory subacute steatohepatitis after biliopancreatic diversion
Sander Lefere
Anne Hoorens
Sarah Raevens
Roberto Troisi
Xavier Verhelst
Hans Van Vlierberghe
Anja Geerts
Editorial material
2017
Serum vascular cell adhesion molecule-1 predicts significant liver fibrosis in non-alcoholic fatty liver disease
Sander Lefere
Frederique Van de Velde
Lindsey Devisscher
Marlies Bekaert
Sarah Raevens
Xavier Verhelst
Yves Van Nieuwenhove
Marleen Praet
Anne Hoorens
Christophe Van Steenkiste
et al.
A1
Journal Article
in
INTERNATIONAL JOURNAL OF OBESITY
2017
Serum vascular cell adhesion molecule-1 predicts significant liver fibrosis in obese patients with non-alcoholic fatty liver disease
Sander Lefere
Frederique Van de Velde
Lindsey Devisscher
Marlies Bekaert
Sarah Raevens
Xavier Verhelst
Yves Van Nieuwenhove
Marleen Praet
Anne Hoorens
Christophe Van Steenkiste
et al.
C3
Conference
2017
Serum vascular cell adhesion molecule-1 predicts significant liver fibrosis in obese patients with non-alcoholic fatty liver disease
Sander Lefere
Frederique Van de Velde
Lindsey Devisscher
Marlies Bekaert
Sarah Raevens
Xavier Verhelst
Yves Van Nieuwenhove
Marleen Praet
Anne Hoorens
Christophe Van Steenkiste
et al.
C3
Conference
2017
What to expect from reliability and validity claims? A pragmatic conception of psychiatric nosology
Sander Lefere
Ruben De Rouck
Leen De Vreese
A1
Journal Article
in
JOURNAL OF EVALUATION IN CLINICAL PRACTICE
2017
2016
Hypoxia-regulated mechanisms in the pathogenesis of obesity and non-alcoholic fatty liver disease
Sander Lefere
Christophe Van Steenkiste
Xavier Verhelst
Hans Van Vlierberghe
Lindsey Devisscher
Anja Geerts
A1
Journal Article
in
CELLULAR AND MOLECULAR LIFE SCIENCES
2016
Kinetics of pulmonary angiogenesis in mouse common bile duct ligation-induced liver fibrosis
Sarah Raevens
Lindsey Devisscher
Annelies Paridaens
Eliene Bogaerts
Sander Lefere
Yves-Paul Vandewynckel
CHRISTINE CASTELEYN
Ken Bracke
Tania Maes
Xavier Verhelst
et al.
C3
Conference
2016
Placental growth factor inhibition alleviates hepatopulmonary syndrome in mice
Sarah Raevens
Annelies Paridaens
Sander Lefere
Bart Jonckx
Xavier Verhelst
Hans Van Vlierberghe
Christophe Van Steenkiste
Anja Geerts
Lindsey Devisscher
Isabelle Colle
C3
Conference
2016