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Onderzoeker
Pauline De Bruyne
Profiel
Projecten
Publicaties
Activiteiten
76
Resultaten
2022
Population pharmacokinetics and Bayesian estimations of lisinopril at steady state in hypertensive children with mild to moderate renal impairment
Eva Degraeuwe
Louis Sandra
Elke Gasthuys
An Vermeulen
Pauline De Bruyne
Ann Raes
Johan Vande Walle
U
Conferentie
2022
2021
Desmopressin oral lyophilisate in young children : new insights in pharmacokinetics and pharmacodynamics
Lien Dossche
Robin Michelet
Pauline De Bruyne
Charlotte Van Herzeele
Elke Gasthuys
An Vermeulen
Johan Vande Walle
A1
Artikel in een tijdschrift
in
ARCHIVES OF DISEASE IN CHILDHOOD
2021
Pharmacokinetics and blood pressure effects of ACE-inhibitors in children with hypertension
Louis Sandra
Eva Degraeuwe
Elke Gasthuys
An Vermeulen
Pauline De Bruyne
Ann Raes
Johan Vande Walle
C3
Conferentie
2021
Successful liver transplantation in hyperornithinemia–hyperammonemia–homocitrullinuria syndrome : case report
Pauline De Bruyne
Saskia Vande Velde
Myriam Van Winckel
Stephanie Van Biervliet
Ruth De Bruyne
A1
Artikel in een tijdschrift
in
PEDIATRIC TRANSPLANTATION
2021
2020
An integrated paediatric population PK/PD analysis of dDAVP : how do PK differences translate to clinical outcomes?
Robin Michelet
Lien Dossche
Charlotte Van Herzeele
Pauline De Bruyne
Elke Gasthuys
Jan Van Bocxlaer
Johan Vande Walle
An Vermeulen
A1
Artikel in een tijdschrift
in
CLINICAL PHARMACOKINETICS
2020
Medical devices that look like medicines : safety and regulatory concerns for children in Europe
Pauline De Bruyne
Saskia Vande Velde
Ruth De Bruyne
Stephanie Van Biervliet
Myriam Van Winckel
A1
Artikel in een tijdschrift
in
ARCHIVES OF DISEASE IN CHILDHOOD
2020
2019
Fluoroquinolones for children : filling the gap
Kevin Meesters
Johan Vande Walle
Pauline De Bruyne
Proefschrift
2019
Paediatric medecines intiatives : how far have we come?
Pauline De Bruyne
Johan Vande Walle
A2
Artikel in een tijdschrift
in
BELGIAN JOURNAL OF PAEDIATRICS
2019
The perspectives of parents, general practitioners, and community pharmacists about treating an ill child in primary care : a comparative study
Sigrid Verhelst
Pauline De Bruyne
Myriam Van Winckel
Koen Boussery
Eline Tommelein
A1
Artikel in een tijdschrift
in
EUROPEAN JOURNAL OF PEDIATRICS
2019
2018
A novel approach in paediatric drug research : the development of a juvenile pig model for pharmacokinetic/pharmacodynamic studies, using desmopressin as case 1
Elke Gasthuys
Joske Millecam
Mathias Devreese
An Vermeulen
Pauline De Bruyne
Johan Vande Walle
Joris Delanghe
Siska Croubels
C3
Conferentie
2018
Does one size of desmopressin oral lyophilisate formulation really fits them all? : exploring the need to perform pharmacokinetic- and pharmacodynamic trials in children
Lien Dossche
Robin Michelet
Ann Raes
Pauline De Bruyne
Johan Vande Walle
C3
Conferentie
2018
Ethical considerations of researchers conducting pediatric clinical drug trials : a qualitative survey in two Belgian university children's hospitals
Kevin Meesters
Lien Dossche
Daphné Christiaens
Pauline De Bruyne
Johan Vande Walle
A1
Artikel in een tijdschrift
in
EUROPEAN JOURNAL OF PEDIATRICS
2018
Medical devices marketed as medicins : safety and regulatory concerns in children
Pauline De Bruyne
Myriam Van Winckel
C3
Conferentie
2018
PK/PD studies in pigs leading to optimization of treatment dose in MNE?
Elke Gasthuys
Lien Dossche
Siska Croubels
Pauline De Bruyne
Mathias Devreese
An Vermeulen
Johan Vande Walle
C3
Conferentie
2018
Pediatric drug development: towards maturity : desmopressin as a case
Elke Gasthuys
Robin Michelet
Lien Dossche
Pauline De Bruyne
Johan Vande Walle
An Vermeulen
Mathias Devreese
Siska Croubels
C3
Conferentie
2018
Population pharmacokinetic modeling of a desmopressin oral lyophilisate in growing piglets as a model for the pediatric population
Elke Gasthuys
An Vermeulen
Siska Croubels
Joske Millecam
Stijn Schauvliege
Thomas van Bergen
Pauline De Bruyne
Johan Vande Walle
Mathias Devreese
A1
Artikel in een tijdschrift
in
FRONTIERS IN PHARMACOLOGY
2018
Population pharmacokinetic modeling of a desmopressin oral lyophilisate in growing piglets as a model for the pediatric population
Elke Gasthuys
An Vermeulen
Siska Croubels
Pauline De Bruyne
Joske Millecam
Johan Vande Walle
Mathias Devreese
C3
Conferentie
2018
Systemic fluoroquinolone prescriptions for hospitalized children in Belgium, results of a multicenter retrospective drug utilization study
Kevin Meesters
Evelyn Dhont
Johan Vande Walle
Pauline De Bruyne
A1
Artikel in een tijdschrift
in
BMC INFECTIOUS DISEASES
2018
The SAFE-PEDRUG project : an opportunity for academia to close the gap
Pauline De Bruyne
Johan Vande Walle
C3
Conferentie
2018
Toxicity of long-term use of proton pump inhibitors in children
Pauline De Bruyne
A1
Artikel in een tijdschrift
in
ARCHIVES OF DISEASE IN CHILDHOOD
2018
2017
Adherence to labeling guidelines, the case of fluoroquinolones : results of a retrospective multicenter drug utilization study
Kevin Meesters
Johan Vande Walle
Pauline De Bruyne
C3
Conferentie
2017
Are antihistamines effective in children? : a review of the evidence
Pauline De Bruyne
Thierry Christiaens
Koen Boussery
Els Mehuys
Myriam Van Winckel
A1
Artikel in een tijdschrift
in
ARCHIVES OF DISEASE IN CHILDHOOD
2017
Confirmation of an ARID2 defect in SWI/SNF-related intellectual disability
Ruben Van Paemel
Pauline De Bruyne
Saskia van der Straaten
Marleen D'Hondt
Annelies Dheedene
Björn Menten
Bert Callewaert
A1
Artikel in een tijdschrift
in
AMERICAN JOURNAL OF MEDICAL GENETICS PART A
2017
Pediatrisch geneesmiddelenonderzoek : een opportuniteit voor academische onderzoeksgroepen
Pauline De Bruyne
Johan Vande Walle
A2
Artikel in een tijdschrift
in
PERCENTIEL (NEDERLANDSE ED.)
2017
The SAFE-PEDRUG initiative : an opportunity for academia to close the gap
Pauline De Bruyne
Johan Vande Walle
C3
Conferentie
2017
The SAFE-PEDRUG initiative : an opportunity for academia to close the gap
Pauline De Bruyne
Johan Vande Walle
C3
Conferentie
2017
Therapeutic efficacy and safety of ACE inhibitors in the hypertensive paediatric population : a review
Evelien Snauwaert
Johan Vande Walle
Pauline De Bruyne
A1
Artikel in een tijdschrift
in
ARCHIVES OF DISEASE IN CHILDHOOD
2017
2016
Bioequivalence in adults does not mean bioequivalence in children
Lien Dossche
Robin Michelet
Pauline De Bruyne
Jan Van Bocxlaer
An Vermeulen
Johan Vande Walle
C3
Conferentie
2016
Bioequivalence in adults is not always bioequivalence in children
Lien Dossche
Ann Raes
Pauline De Bruyne
Robin Michelet
An Vermeulen
Jan Van Bocxlaer
Johan Vande Walle
C3
Conferentie
2016
Circadian rhythm of glomerular filtration and solute handling related to nocturnal enuresis
Lien Dossche
Ann Raes
Piet Hoebeke
Pauline De Bruyne
Johan Vande Walle
A1
Artikel in een tijdschrift
in
JOURNAL OF UROLOGY
2016
Effect of food and pharmaceutical formulation on desmopressin pharmacokinetics in children
Robin Michelet
Lien Dossche
Pauline De Bruyne
Pieter Colin
Koen Boussery
Johan Vande Walle
Jan Van Bocxlaer
An Vermeulen
C3
Conferentie
2016
Effect of food and pharmaceutical formulation on desmopressin pharmacokinetics in children
Robin Michelet
Lien Dossche
Pauline De Bruyne
Pieter Colin
Koen Boussery
Johan Vande Walle
Jan Van Bocxlaer
An Vermeulen
C3
Conferentie
2016
Effects of food and pharmaceutical formulation on desmopressin pharmacokinetics in children
Robin Michelet
Lien Dossche
Pauline De Bruyne
Pieter Colin
Koen Boussery
Johan Vande Walle
Jan Van Bocxlaer
An Vermeulen
A1
Artikel in een tijdschrift
in
CLINICAL PHARMACOKINETICS
2016
Farmacotherapeutische actualiteit
Thierry Christiaens
Pauline De Bruyne
Lucas Van Bortel
Redactioneel materiaal
2016
How do researchers weigh ethical priciples in pediatric clinical trials?
Wannes Van Hoof
Pauline De Bruyne
Lien Dossche
Sofie Bekaert
Johan Vande Walle
C3
Conferentie
2016
Paediatric drug development : an opportunity for academia to close the gap
Pauline De Bruyne
Johan Vande Walle
Myriam Van Winckel
Proefschrift
2016
Predictive value of urinary osmolality in the early morning for desmopressin response
Lien Dossche
Ann Raes
Pauline De Bruyne
Johan Vande Walle
C3
Conferentie
2016
SAFE-PEDRUG : a new strategy for paediatric drug research
Pauline De Bruyne
Kevin Meesters
Johan Vande Walle
C3
Conferentie
2016
The potential use of piglets as human pediatric surrogate for preclinical pharmacokinetic and pharmacodynamic drug testing
Elke Gasthuys
Tim Vandecasteele
Pauline De Bruyne
Johan Vande Walle
Patrick De Backer
Pieter Cornillie
Mathias Devreese
Siska Croubels
A1
Artikel in een tijdschrift
in
CURRENT PHARMACEUTICAL DESIGN
2016
Therapeutic efficacy and safety of ACE inhibitors in the hypertensive paediatric population: a review
Evelien Snauwaert
Johan Vande Walle
Pauline De Bruyne
C3
Conferentie
2016
Use of fluoroquinolones in hospitalized children : preliminary report of a chart review in a Belgian university children's hospital
Kevin Meesters
Pauline De Bruyne
Johan Vande Walle
C3
Conferentie
2016
Vascular disorders of the liver
Ruth De Bruyne
Pauline De Bruyne
Hoofdstuk in een boek
in
Textbook of pediatric gastroenterology, hepatology and nutrition : a comprehensive guide to practice
2016
2015
A substitution error leading to central anticholinergic syndrome
Pauline De Bruyne
C3
Conferentie
2015
Angiotensin converting enzyme inhibitors in pediatrics : state of the art
Evelien Snauwaert
Pauline De Bruyne
Johan Vande Walle
C3
Conferentie
2015
Challenging factors for enuresis treatment: psychological problems and non-adherence
Charlotte Van Herzeele
Pauline De Bruyne
Johan Vande Walle
A1
Artikel in een tijdschrift
in
JOURNAL OF PEDIATRIC UROLOGY
2015
Complicated urinary tract infection in a two months old infant : which drug to choose
Kevin Meesters
Pauline De Bruyne
Johan Vande Walle
C3
Conferentie
2015
Farmacotherapeutische actualiteit
Pauline De Bruyne
Pieter Depuydt
Lucas Van Bortel
Thierry Christiaens
Redactioneel materiaal
2015
Fluoroquinolones in children where an old enemy becomes a friend
Pauline De Bruyne
Johan Vande Walle
C3
Conferentie
2015
Fluoroquinolones in children with urinary tract infections: old enemy or new friend? : a review of current litterature
Johan Vande Walle
Pauline De Bruyne
Kevin Meesters
C3
Conferentie
2015
How safe is on-label drug use in paediatrics? : the case of first generation H1-antihistamines
Pauline De Bruyne
Koen Boussery
Thierry Christiaens
Els Mehuys
Myriam Van Winckel
C3
Conferentie
2015
Management of hypertension in children and adolescents
Pauline De Bruyne
Johan Vande Walle
A1
Artikel in een tijdschrift
in
ACTA CLINICA BELGICA
2015
Possible confounders in the reported association between autism spectrum disorder (ASD) and exposure to selective serotonin reuptake inhibitors (SSRIs) during pregnancy
Pauline De Bruyne
C3
Conferentie
2015
SAFE PEDDRUG: the next step in ethical paediatric drug research
Pauline De Bruyne
Johan Vande Walle
C3
Conferentie
2015
SAFE-PEDRUG : a new strategy for paediatric drug research
Pauline De Bruyne
Kevin Meesters
Johan Vande Walle
C3
Conferentie
2015
Use of fluoroquinolones in hospitalized children : preliminary report of a chart review in a Belgian university children's hospital
Kevin Meesters
Pauline De Bruyne
Johan Vande Walle
C3
Conferentie
2015
2014
Adult bioequivalence studies insufficient for paediatric use: the case of desmopressin
Pauline De Bruyne
Ann De Guchtenaere
Charlotte Van Herzeele
Ann Raes
Jo Dehoorne
Piet Hoebeke
Erik Van Laecke
Johan Vande Walle
C3
Conferentie
2014
Changes in presciption patterns of acid-suppressant medications by Belgian pediatricians: analysis of the national database, [1997-2009]
Pauline De Bruyne
Thierry Christiaens
Robert Vander Stichele
Myriam Van Winckel
A1
Artikel in een tijdschrift
in
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
2014
Pharmacokinetics of desmopressin administered as tablet and oral lyophilisate formulation in children with monosymptomatic nocurnal enuresis
Pauline De Bruyne
Ann De Guchtenaere
Charlotte Van Herzeele
Ann Raes
Jo Dehoorne
Piet Hoebeke
Erik Van Laecke
Johan Vande Walle
A1
Artikel in een tijdschrift
in
EUROPEAN JOURNAL OF PEDIATRICS
2014
Safety profile of desmopressin tablet for enuresis in a prospective study
Charlotte Van Herzeele
Pauline De Bruyne
Johan Vande Walle
A1
Artikel in een tijdschrift
in
ADVANCES IN THERAPY
2014
Successful liver transplantation in hyperornithinemia-hyperammonemia-homocitrullinuria syndrome
Pauline De Bruyne
Stephanie Van Biervliet
Myriam Van Winckel
Saskia Vande Velde
Ruth De Bruyne
C3
Conferentie
2014
2013
Desmopressin melt improves response and compliance compared with tablet in treatment of primary monosymptomatic nocturnal enuresis
Charlotte Van Herzeele
Pauline De Bruyne
Johan Vande Walle
A1
Artikel in een tijdschrift
in
EUROPEAN JOURNAL OF PEDIATRICS
2013
Is there a gender difference in antidiuretic response to desmopressin in children?
Pauline De Bruyne
Johan Vande Walle
A2
Artikel in een tijdschrift
in
OPEN JOURNAL OF PEDIATRICS
2013
Weight depending dosing of desmopressin (dDAVP) in nocturnal enuresis
Pauline De Bruyne
Ann De Guchtenaere
Charlotte Van Herzeele
Ann Raes
Jo Dehoorne
Piet Hoebeke
Erik Van Laecke
Johan Vande Walle
C3
Conferentie
2013
2012
Desmopressin oral lyophylysate formulation (MELT) : a solution for insufficient desmopressin tablet response in monosymptomatic nocturnal enuresis?
Pauline De Bruyne
Ann De Guchtenaere
Charlotte Van Herzeele
Jo Dehoorne
Ann Raes
Piet Hoebeke
Erik Van Laecke
Johan Vande Walle
C3
Conferentie
2012
Evolution of antireflux medication prescriptions in Belgium over the last decade
Pauline De Bruyne
Robert Vander Stichele
Thierry Christiaens
Marcus Bogaert
Myriam Van Winckel
C3
Conferentie
2012
First evidence for weight-dependent dosing of desmopressin
Pauline De Bruyne
Ann De Guchtenaere
C3
Conferentie
2012
2011
Liver transplantation for neonatal acute liver failure
Pauline De Bruyne
Ruth De Bruyne
C3
Conferentie
2011
Person-to-person transmission of strongyloides stercoralis
Pauline De Bruyne
Myriam Van Winckel
Ruth De Bruyne
C3
Conferentie
2011
Pharmacokinetic characteristics of desmopressin oral lyophilisate (MELT) and tablet formulation in children
Ann De Guchtenaere
Charlotte Van Herzeele
Pauline De Bruyne
Jo Dehoorne
Ann Raes
Johan Vande Walle
C3
Conferentie
2011
Pharmacokinetic characteristics of desmopressin oral lyophilisate (MELT) and tablet formulation in children.
Ann De Guchtenaere
Piet Hoebeke
Charlotte Van Herzeele
Jo Dehoorne
Ann Raes
Erik Van Laecke
Pauline De Bruyne
Johan Vande Walle
C3
Conferentie
2011
Pharmalogical treatment for gastroesophageal reflux disease in children
Pauline De Bruyne
A2
Artikel in een tijdschrift
in
TIJDSCHRIFT VAN DE BELGISCHE KINDERARTS = JOURNAL DU PEDIATRE BELGE
2011
W.J.H.M. van den Bosch, A.J. van der Heijden, R.N. Sukhai, J. Waveling (red.): Het pediatrisch formularium: een praktische leidraad (vijfde, herziene druk.)
Pauline De Bruyne
Boek recensie
2011
2010
Leverlijden, een verraderlijke verwikkeling van mucoviscidose
Pauline De Bruyne
Marleen Genetello
Eddy Robberecht
A2
Artikel in een tijdschrift
in
TIJDSCHRIFT VOOR GENEESKUNDE
2010
2009
A potentially life-treatening complication after a blood transfusion : the importance of clinical awareness
Pauline De Bruyne
Jef Willems
C3
Conferentie
2009
Importance of hepatitis A vaccination in children travelling to developing countries : 2 case reports
Pauline De Bruyne
Ruth De Bruyne
Bernard de Hemptinne
Stephanie Van Biervliet
C3
Conferentie
2009
Person-to-person transmission of strongyloides stercoralis in an immunocompromised patient
Pauline De Bruyne
Myriam Van Winckel
Ruth De Bruyne
C3
Conferentie
2009