Research Explorer

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Researcher

Olga Krysko

Awards & Distinctions

79 Results

2024

Glioma : bridging the tumor microenvironment, patient immune profiles and novel personalized immunotherapy

Tatiana A. MishchenkoVictoria D. TurubanovaEkaterina N. GorshkovaOlga KryskoMaria V. VedunovaDmitri Krysko

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Targeting immunogenic cell death for glioma immunotherapy

Tatiana A. MishchenkoVictoria D. TurubanovaEkaterina N. GorshkovaOlga KryskoMaria V. VedunovaDmitri Krysko

Editorial material

2023

Dendritic cells pulsed with tumor lysates induced by tetracyanotetra(aryl)porphyrazines-based photodynamic therapy effectively trigger anti-tumor immunity in an orthotopic mouse glioma model

Tikhon S. RedkinEkaterina E. SleptsovaVictoria D. TurubanovaMariia SaviukSvetlana A. LermontovaLarisa G. KlapshinaNina N. PeskovaIrina V. BalalaevaOlga KryskoTatiana A. Mishchenko et al.

A1 Journal Article in PHARMACEUTICS

Differential protease content of mast cells and the processing of IL-33 in Alternaria alternata induced allergic airway inflammation in mice

Olga KryskoDarya KorsakovaAndrea Renate TeufelbergerAmse De MeyerJill SteelsNatalie De RuyckJudith van OvostSharon Van NevelGabriële HoltappelsFrauke Coppieters et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

2022

DC vaccines loaded with glioma cells killed by photodynamic therapy induce Th17 anti-tumor immunity and provide a four-gene signature for glioma prognosis

Maria VedunovaVictoria TurubanovaOlga VershininaMariia SaviukIuliia EfimovaTatiana MishchenkoRobrecht RaedtAnne VralChristian VanhoveDaria Korsakova et al.

A1 Journal Article in CELL DEATH & DISEASE

In vitro veritas : from 2D cultures to organ-on-a-chip models to study immunogenic cell death in the tumor microenvironment

Dmitri KryskoRobin DemuynckIuliia EfimovaFaye NaessensOlga KryskoElena Catanzaro

A1 Journal Article in CELLS

Severity of SARS-CoV-2 infection is associated with high numbers of alveolar mast cells and their degranulation

Olga KryskoJoshua H. BourneElena KondakovaElena A. GalovaKatharine WhitworthMaddy L. NewbyClaus BachertHarriet HillMax CrispinZania Stamataki et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

2021

Analysis of immunogenic cell death in the tumor microenvironment of tumor spheroids

Robin DemuynckIuliia EfimovaOlga KryskoHeidi DeclercqDmitri Krysko

Artificial intelligence predicts severity of COVID-19 based on correlation of exaggerated monocyte activation, excessive organ damage and hyperinflammatory syndrome : a prospective clinical study

Olga KryskoElena KondakovaOlga VershininaElena GalovaAnna BlagonravovaEkaterina GorshkovaClaus BachertMikhail IvanchenkoDmitri KryskoMaria Vedunova

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Cell death stage dictates the immunogenicity of ferroptotic cancer cells

Iuliia EfimovaElena CatanzaroRobin DemuynckLouis Van der MeerenFrauke CoppietersClaus BachertAndre SkirtachOlga KryskoDmitri Krysko

Early but not late ferroptotic cancer cells are immunogenic in vitro and in vivo

Iuliia EfimovaElena CatanzaroLouis Van der MeerenClaus BachertAndre SkirtachOlga KryskoDmitri Krysko

Immunogenic cell death in photodynamic-induced tumor cells based on photosens and photodithazine

Viktoria TurubanovaIuliia EfimovaTatiana MishchenkoElena CatanzaroIrina BalalaevaClaus BachertOlga KryskoMaria VedunovaDmitri Krysko

Immunogenic cell death induced by PDT : a new approach for cancer therapy

Dmitri KryskoVictoria TurubanovaTatiana MishchenkoIrina BalalaevaIuliia EfimovaOlga KryskoMaria Vedunova

Neutrophils affect IL-33 processing in response to the respiratory allergen Alternaria alternata

Sharon Van NevelJudith van OvostGabriële HoltappelsNatalie De RuyckNan ZhangHarald BraunTania MaesClaus BachertOlga Krysko

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Novel porphyrazine-based photodynamic anti-cancer therapy induces immunogenic cell death

Victoria D. TurubanovaTatiana A. MishchenkoV Balalaeva, IrinaIuliia EfimovaNina N. PeskovaLarisa G. KlapshinaSvetlana A. LermontovaClaus BachertOlga KryskoMaria V. Vedunova et al.

A1 Journal Article in SCIENTIFIC REPORTS

2020

Biologics for chronic rhinosinusitis with nasal polyps

Claus BachertNan ZhangCarlo CavaliereWen Weiping Wen WeipingElien GevaertOlga Krysko

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Differential response of C57BL/6 and BALB/c mice in Alternaria alternata-induced allergic airway inflammation

Sharon Van NevelNatalie De RuyckGabriële HoltappelsClaus BachertOlga Krysko

Functional characterization of the first missense variant in CEP78, a founder allele associated with cone‐rod dystrophy, hearing loss and reduced male fertility

Giulia AscariFrank PeelmanPietro FarinelliToon RosseelNina LambrechtsKirsten A. WunderlichMatias WagnerKonstantinos NikopoulosPernille MartensIrina Balikova et al.

A1 Journal Article in HUMAN MUTATION

Identification of a novel pathway in immune response towards S. aureus protease like protein D

Olga KryskoAndrea Renate TeufelbergerSharon Van NevelSzanne De GraevePaco HulpiauM. NordengruenB. M. BroekerDmitri KryskoClaus Bachert

Mouse strain-dependent difference toward the staphylococcus aureus allergen serine protease-like protein D reveals a novel regulator of IL-33

Andrea Renate TeufelbergerSharon Van NevelPaco HulpiauMaria NordengrünSavvas SavvidesSarah De GraeveSrinivas AkulaGabriële HoltappelsNatalie De RuyckWim Declercq et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Perspective : COVID-19, implications of nasal diseases and consequences for their management

Li JianWei YiNan ZhangWeiping WenOlga KryskoWoo-Jung SongClaus Bachert

Editorial material

Vaccination with early ferroptotic cancer cells induces efficient antitumor immunity

Iuliia EfimovaElena CatanzaroLouis Van der MeerenVictoria TurubanovaHamida HammadTatiana MishchenkoMaria VedunovaCarmela FimognariClaus BachertFrauke Coppieters et al.

A1 Journal Article in JOURNAL FOR IMMUNOTHERAPY OF CANCER

mRNA encoding a bispecific single domain antibody construct protects against influenza A virus infection in mice

Lien Van HoeckeRein VerbekeDorien De VliegerHeleen DewitteKenny RooseSharon Van NevelOlga KryskoClaus BachertBert SchepensIne Lentacker et al.

A1 Journal Article in MOLECULAR THERAPY-NUCLEIC ACIDS

2019

An emerging role for nanomaterials in increasing immunogenicity of cancer cell death

Tatiana MishchenkoElena MitroshinaIrina BalalaevaOlga KryskoMaria VedunovaDmitri Krysko

A1 Journal Article in BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Expansion of the role and functional characterization of a missense variant in CEP78 associated with cone-rod dystrophy and hearing loss

Giulia AscariFrank PeelmanPietro FarinelliToon RosseelNina LambrechtsIrina BalikovaLara DeryckeGabriële HoltappelsOlga KryskoThalia Van Laethem et al.

Immunogenic cell death induced by a new photodynamic therapy based on photosens and photodithazine

Victoria D TurubanovaIrina V BalalaevaTatiana A MishchenkoElena CatanzaroRazan AlzeibakNina N PeskovaIuliia EfimovaClaus BachertElena V MitroshinaOlga Krysko et al.

A1 Journal Article in JOURNAL FOR IMMUNOTHERAPY OF CANCER

Protease/antiprotease network in allergy : the role of Staphylococcus aureus protease-like proteins

Olga KryskoAndrea Renate TeufelbergerSharon Van NevelDmitri KryskoClaus Bachert

A1 Journal Article in ALLERGY

Redox (phospho)lipidomics of signaling in inflammation and programmed cell death

YY TyurinaCM St CroixSC WatkinsAM WatsonMW EpperlyTS AnthonymuthuER KisinII VlasovaOlga KryskoDmitri Krysko et al.

A1 Journal Article in JOURNAL OF LEUKOCYTE BIOLOGY

Staphylococcus aureus orchestrates type 2 airway diseases

Andrea Renate TeufelbergerBarbara M. BrökerDmitri KryskoClaus BachertOlga Krysko

A1 Journal Article in TRENDS IN MOLECULAR MEDICINE

2018

IL-33 signalling contributes to pollutant-induced allergic airway inflammation

Katrien De GroveSharen ProvoostHarald BraunEvy BlommeAndrea Renate TeufelbergerOlga KryskoRudi BeyaertGuy BrusselleGuy JoosTania Maes

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Lipid homeostasis and inflammatory activation are disturbed in classically activated macrophages with peroxisomal β-oxidation deficiency

Ivana GericYulia Y TyurinaOlga KryskoDmitri KryskoEvelyn De SchryverValerian E KaganPaul P Van VeldhovenMyriam BaesSimon Verheijden

A1 Journal Article in IMMUNOLOGY

Staphylococcus aureus induces a mucosal type 2 immune response via epithelial cell-derived cytokines

Feng LanNan ZhangGabriële HoltappelsNatalie De RuyckOlga KryskoKoen Van CrombruggenHarald BraunSebastian L JohnstonNikos G PapadopoulosLuo Zhang et al.

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The IL-33/ST2 axis is crucial in type 2 airway responses induced by Staphylococcus aureus-derived serine protease-like protein D

Andrea Renate TeufelbergerMaria NordengrünHarald BraunTania MaesKatrien De GroveGabriële HoltappelsClara O'BrienSharen ProvoostHamida HammadAmanda Gonçalves et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The interplay of the staphylococcal protease SplD and IL-33 in the development of allergic asthma in mice

Andrea Renate TeufelbergerClaus BachertOlga KryskoDmitri Krysko

2017

EUFOREA Rhinology Research Forum 2016 : report of the brainstorming sessions on needs and priorities in rhinitis and rhinosinusitis

PW HellingsCA AkdisClaus BachertJ BousquetB PuginG AdriaensenR AdvaniI AgacheC AnjoR Anmolsingh et al.

A1 Journal Article in RHINOLOGY

Extracellular eosinophilic traps in association with Staphylococcus aureus at the site of epithelial barrier defects in patients with severe airway inflammation

Elien GevaertNan ZhangOlga KryskoFeng LanGabriële HoltappelsNatalie De RuyckHans NauwynckShida YousefiHans-Uwe SimonClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Low concentration of uncouplers of oxidative phosphorylation decreases the TNF-induced endothelial permeability and lethality in mice

Vlada V ZakharovaOlga Yu PletjushkinaIvan I GalkinRoman A ZinovkinBoris V ChernyakDmitri KryskoClaus BachertOlga KryskoVladimir P SkulachevEkaterina N Popova

A1 Journal Article in BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Missense mutation in CEP78 in a family with cone-rod dystrophy, sensorineural hearing loss, obesity and subfertility

Giulia AscariStijn Van de SompeleLara DeryckeGabriële HoltappelsOlga KryskoJo Van DorpeDavid CreytensThalia Van LaethemIrina BalikovaJan Gerris et al.

Missense mutation in CEP78 in a family with cone-rod dystrophy, sensorineural hearing loss, obesity and subfertility.

Giulia AscariStijn Van de SompeleLara DeryckeGabriële HoltappelsOlga KryskoJo Van DorpeDavid CreytensThalia Van LaethemIrina BalikovaJan Gerris et al.

Nasal polyposis and asthma : a mechanistic paradigm focusing on Staphylococcus aureus

Claus BachertNan ZhangOlga KryskoKoen Van CrombruggenElien Gevaert

Bookchapter in The nose and sinuses in respiratory disorders

Necroptotic cell death in anti-cancer therapy

Olga KryskoTania Love AaesValerian E KaganKatharina D'HerdeClaus BachertLuc LeybaertPeter VandenabeeleDmitri Krysko

A1 Journal Article in IMMUNOLOGICAL REVIEWS

Staphylococcal serine protease-like proteins are pacemakers of allergic airway reactions to Staphylococcus aureus

Sebastian StentzelAndrea Renate TeufelbergerMaria NordengrünJulia KolataFrank SchmidtKoen Van CrombruggenStephan MichalikJana KumpfmüllerSebastian TischerThomas Schweder et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The IL-33/ST2 axis is crucial in type 2 airway responses induced by the Staphylococcus aureus protease SpID

Olga KryskoAndrea Renate TeufelbergerMaria NordengrunTania MaesBarbara BrokerClaus Bachert

2016

Immunogenic apoptotic cell death and anticancer immunity

Peter VandenabeeleKatrien VandecasteeleClaus BachertOlga KryskoDmitri Krysko

A1 Journal Article in Advances in Experimental Medicine and Biology

SplD- : a novel inhalant allergen from S. aureus causes Th2 bias in mice

Olga KryskoAndrea Renate TeufelbergerSebastian StentzelKatrien De GroveTania MaesGabriële HoltappelsBarbara BroekerClaus Bachert

The protease SplD provides a link between asthma and mucosal S. aureus colonization

Andrea Renate TeufelbergerS StentzelHarald BraunTania MaesGabriële HoltappelsSharen ProvoostKatrien De GroveRudi BeyaertDmitri KryskoB Broeker et al.

2015

Characterization of the in vivo immune network of IDO, tryptophan metabolism, PD-L1, and CTLA-4 in circulating immune cells in melanoma

Ines ChevoletReinhart SpeeckaertMax SchreuerB NeynsOlga KryskoClaus BachertB HennartD AllorgeNanja van GeelMireille Van Gele et al.

A1 Journal Article in ONCOIMMUNOLOGY

Clinical significance of plasmacytoid dendritic cells and myeloid-derived suppressor cells in melanoma

Ines ChevoletReinhart SpeeckaertMax SchreuerBart NeynsOlga KryskoClaus BachertMireille Van GeleNanja van GeelLieve Brochez

A1 Journal Article in JOURNAL OF TRANSLATIONAL MEDICINE

Nasal immunity, rhinitis, rhinosinustis

Claus BachertOlga KryskoPhilippe GevaertMargot BeringsClaudina Perez NovoKoen Van Crombruggen

Bookchapter in Mucosal immunology

2014

Staphyloccoccus aureus elicit epithelial cell-derived cytokine productions in human nasal tissue

F LanNan ZhangDX WangOlga KryskoGabriële HoltappelsNG PapadopoulosSL JohnstonClaus Bachert

2013

Bone grafts engineered from human adipose-derived stem cells in dynamic 3D-environments

Heidi DeclercqTamara De CaluwéOlga KryskoClaus BachertMaria Cornelissen

A1 Journal Article in BIOMATERIALS

Forkhead box P3 in human airway regulatory T cells is regulated by suppressor of cytokine signaling

F LanNan ZhangJ ZhangOlga KryskoQ ZhangJ XianLara DeryckeY QiK LiS Liu et al.

Forkhead box protein 3 in human nasal polyp regulatory T cells is regulated by the protein suppressor of cytokine signaling 3

Feng LanNan ZhangJie ZhangOlga KryskoQuanbo ZhangJunming XianLara DeryckeYanyu QiKai LiShixi Liu et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Many faces of DAMPs in cancer therapy

Olga KryskoTania Love AaesClaus BachertPeter VandenabeeleDmitri Krysko

A1 Journal Article in CELL DEATH & DISEASE

Peroxisomal multifunctional protein-2 deficiency causes neuroinflammation and degeneration of Purkinje cells independent of very long chain fatty acid accumulation

Simon VerheijdenAstrid BottelbergsOlga KryskoDmitri KryskoLien BeckersStephanie De MunterPaul P Van VeldhovenSabine WynsWim KulikKlaus-Armin Nave et al.

A1 Journal Article in NEUROBIOLOGY OF DISEASE

TNF/TNF-R1 pathway is involved in doxorubicin-induced acute sterile inflammation

Agnieszka KaczmarekOlga KryskoLiesbeth HeyndrickxTania Love AaesTinneke DelvaeyeClaus BachertLuc LeybaertPeter VandenabeeleDmitri Krysko

A1 Journal Article in CELL DEATH & DISEASE

The adjuvant-like activity of staphylococcal enterotoxin B in a murine asthma model is independent of IL-1R signaling

Olga KryskoTania MaesMaud PlantingaGabriële HoltappelsRosina ImiruPeter VandenabeeleGuy JoosDmitri KryskoClaus Bachert

A1 Journal Article in ALLERGY

The pathogenesis of CRS : an update

Claus BachertNada Al BahraniSurayie Al DousaryKoen Van CrombruggenOlga KryskoClaudina Perez NovoNan Zhang

A2 Journal Article in CURRENT OTORHINOLARYNGOLOGY REPORTS

2012

Bone grafts engineered from human adipose-derived stem cells in dynamic 3d-environments : a top-down versus bottom-up approach

Heidi DeclercqTamara De CaluwéOlga KryskoClaus BachertMaria Cornelissen

ER stress-induced inflammation: does it aid or impede disease progression?

Abhishek GargAgnieszka KaczmarekOlga KryskoPeter VandenabeeleDmitri KryskoPatrizia Agostinis

A1 Journal Article in TRENDS IN MOLECULAR MEDICINE

Efficient derivation of mesenchymal stem cells from human embryonic stem cells for tissue engineering

Heidi DeclercqWai TamOlga KryskoClaus BachertMaria Cornelissen

Herpes simplex virus type 1 infection facilitates invasion of Staphylococcus aureus into the nasal mucosa and nasal polyp tissue

XiangDong WangNan ZhangSarah GlorieuxGabriële HoltappelsMario VaneechoutteOlga KryskoLuo ZhangDeMin HanHans NauwynckClaus Bachert

A1 Journal Article in PLOS ONE

Immunogenic cell death and DAMPs in cancer therapy

Dmitri KryskoAbhishek D GargAgnieszka KaczmarekOlga KryskoPatrizia AgostinisPeter Vandenabeele

A1 Journal Article in NATURE REVIEWS CANCER

Local inflammation in chronic upper airway disease

Lien CalusThibaut Van ZeleLara DeryckeOlga KryskoTineke DutréPeter TomassenMelissa DullaersClaus BachertPhilippe Gevaert

A1 Journal Article in CURRENT PHARMACEUTICAL DESIGN

2011

Alternatively activated macrophages and impaired phagocytosis of S-aureus in chronic rhinosinusitis

Olga KryskoGabriële HoltappelsNan ZhangMalgorzata KubicaKim DeswarteLara DeryckeSofie ClaeysHamida HammadGuy BrussellePeter Vandenabeele et al.

A1 Journal Article in ALLERGY

Emerging role of damage-associated molecular patterns derived from mitochondria in inflammation

Dmitri KryskoPatrizia AgostinisOlga KryskoAbhishek D GargClaus BachertBart LambrechtPeter Vandenabeele

A1 Journal Article in TRENDS IN IMMUNOLOGY

Exacerbation of cigarette smoke-induced pulmonary inflammation by Staphylococcus aureus enterotoxin B in mice

Wouter HuvenneEllen LanckackerOlga KryskoKen BrackeTine DemoorPeter W HellingsGuy BrusselleGuy JoosClaus BachertTania Maes

A1 Journal Article in RESPIRATORY RESEARCH

TLR-2 and TLR-9 are sensors of apoptosis in a mouse model of doxorubicin-induced acute inflammation

Dmitri KryskoAgnieszka KaczmarekOlga KryskoLiesbeth HeyndrickxJerzy WoznickiPieter BogaertAnje CauwelsNozomi TakahashiS MagezClaus Bachert et al.

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

2010

Different regulation of cigarette smoke induced inflammation in upper versus lower airways

Wouter HuvenneClaudina Perez NovoLara DeryckeNatalie De RuyckOlga KryskoTania MaesNele PauwelsLander RobaysKen BrackeGuy Joos et al.

A1 Journal Article in RESPIRATORY RESEARCH

Impairment of phagocytosis of apoptotic cells and its role in chronic airway diseases

Olga KryskoPeter VandenabeeleDmitri KryskoClaus Bachert

A1 Journal Article in APOPTOSIS

MYD88, TLR-2, TLR-9 and TNFR1-dependent signaling is essential for the sterile inflammatory response triggered by doxorubicin

Dmitri KryskoAgnieszka KaczmarekJerzy WoznickiStefan MagezOlga KryskoPieter BogaertPeter Vandenabeele

Peroxisomes in zebrafish: distribution pattern and knockdown studies

Olga KryskoMieke StevensTobias LangenbergMarc FransenMarc EspeelMyriam Baes

A1 Journal Article in HISTOCHEMISTRY AND CELL BIOLOGY

Staphylococcus aureus enterotoxin B facilitates allergic sensitization in experimental asthma

Wouter HuvenneIna CallebautMaud PlantingaJeroen AJ VanoirbeekOlga KryskoDominique MA BullensPhilippe GevaertPaul Van CauwenbergeBart LambrechtJan L Ceuppens et al.

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

2009

Comment on "Potent Phagocytic Activity with impaired Antigen Presentation Identifying Lipopolysaccharide-Tolerant Human Monocytes: Demonstration in Isolated Monocytes from Cystic Fibrosis Patients"

Olga KryskoThibaut Van ZeleSofie ClaeysClaus Bachert

A1 Journal Article in JOURNAL OF IMMUNOLOGY

2008

Absence of functional peroxisomes from mouse CNS causes dysmyelination and axon degeneration

L HULSHAGENOlga KryskoA BOTTELBERGSS HUYGHER KLEINPP VAN VELDHOVENPP DE DEYNR D'HOOGED HARTMANNM BAES

A1 Journal Article in JOURNAL OF NEUROSCIENCE

Tissue distribution of peroxisomes in zebrafish

Mieke StevensOlga KryskoMyriam BaesMarc Espeel

2007

Neocortical and cerebellar developmental abnormalities in conditions of selective elimination of peroxisomes from brain or from liver

Olga KryskoL HULSHAGENA JANSSENG SCHUTZR KLEINMelina De BruyckerMarc EspeelP GRESSENSM BAES

A1 Journal Article in JOURNAL OF NEUROSCIENCE RESEARCH

The role of peroxisomes in neurodevelopment : from mouse models to zebrafish

Olga KryskoM. BaesP. Carmeliet

2004

Phosphatidylserine exposure during early primary necrosis (oncosis) in JB6 cells as evidenced by immunogold labeling technique

Olga KryskoLeo De RidderMaria Cornelissen

A1 Journal Article in APOPTOSIS