Research Explorer

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Researcher

Nora Pauwels

Awards & Distinctions

10 Results

2015

Lipid and carbohydrate modifications of α-galactosylcer-amide differently influence mouse and human type I natural killer T cell activation

Alysia BirkholzMarek NemčovičEsther Dawen YuEnrico GirardiJing WangArchana KhuranaNora PauwelsElisa FarberSampada ChitaleRichard W Franck et al.

A1 Journal Article in JOURNAL OF BIOLOGICAL CHEMISTRY

Synthesis of C-5" and C-6"-modified α-GalCer analogues as iNKT-cell agonists

Joren GuillaumeNora PauwelsSANDRINE ASPESLAGHDirk ZajoncDirk ElewautSerge Van Calenbergh

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY

2013

Synthesis of new α-GalCer analogues as iNKT cell targeting agents

Nora PauwelsSerge Van Calenbergh

2012

Crystal structures of bovine CD1d reveal altered αGalCer presentation and a restricted A' pocket unable to bind long-chain glycolipids

Jing WangJoren GuillaumeNora PauwelsSerge Van CalenberghIldiko Van RhijnDirk M Zajonc

A1 Journal Article in PLOS ONE

Synthesis of 6”-triazole-substituted α-GalCer analogues as potent iNKT cell stimulating ligands

Nora PauwelsSANDRINE ASPESLAGHDirk ElewautSerge Van Calenbergh

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY

Versatile synthesis of C-5" and C-6"-modified α-GalCer analogues as new iNKT cell ligands

Nora PauwelsSANDRINE ASPESLAGHDirk ElewautSerge Van Calenbergh

2011

6''-Modified alpha-GalCer analogs capable of establishing an extra interaction with Cd1d leading to a polarized Th1 response and superior tumor protection

Serge Van CalenberghNora PauwelsSANDRINE ASPESLAGHYaLi LiMatthias TrappeniersDirk ZajoncDirk Elewaut

Divergent synthetic approach to 6''-modified α-GalCer analogues

Nora PauwelsSANDRINE ASPESLAGHGerd VanhoenackerKoen SandraEsther D. YuDirk M. ZajoncDirk ElewautBruno LinclauSerge Van Calenbergh

A1 Journal Article in ORGANIC & BIOMOLECULAR CHEMISTRY

Galactose modified iNKT cell agonists stabilised by a novel structural modification of CD1D lead to marked TH1 polarisation in vivo

SANDRINE ASPESLAGHYaLi LiEsther Dawen YuNora PauwelsMatthias TrappeniersEnrico GirardiTine DecruyKatrien Van BenedenKoen VenkenMichael Drennan et al.

Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis

SANDRINE ASPESLAGHYali LiEsther Dawen YuNora PauwelsMatthias TrappeniersEnrico GirardTine DecruyKatrien Van BenedenKoen VenkenMichael Drennan et al.

A1 Journal Article in EMBO JOURNAL