Research Explorer

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Researcher

Nick Van Laeken

30 Results

2022

Accelerated HF‐rTMS modifies SERT availability in the subgenual anterior cingulate cortex : a canine [11C]DASB study on the serotonergic system

Yangfeng XuMitchel KappenKathelijne PeremansDimitri De BundelAnn Van EeckhoutNick Van LaekenFilip De VosAndré DobbeleirJimmy SaundersChris Baeken

A1 Journal Article in JOURNAL OF NUCLEAR MEDICINE

2020

Intra-individual dynamic comparison of 18F-PSMA-11 and 68Ga-PSMA-11 in LNCaP xenograft bearing mice

Sarah PironJeroen VerhoevenBenedicte DescampsKen KersemansKathia De ManNick Van LaekenLeen PietersAnne VralChristian VanhoveFilip De Vos

A1 Journal Article in SCIENTIFIC REPORTS

Optimization of PET protocol and interrater reliability of 18F-PSMA-11 imaging of prostate cancer

Sarah PironKathia De ManVanessa SchelfhoutNick Van LaekenKen KersemansEric AchtenFilip De VosPiet Ost

A1 Journal Article in EJNMMI RESEARCH

2019

Cortical motor threshold determination in dogs

Robrecht DockxChris BaekenLise VlerickSofie BhattiIngeborgh PolisNick Van LaekenLuc Van HamFilip De VosJimmy SaundersKathelijne Peremans

A1 Journal Article in RESEARCH IN VETERINARY SCIENCE

Radiation dosimetry and biodistribution of 18F-PSMA-11 for PET imaging of prostate cancer

Sarah PironKathia De ManNick Van LaekenYves D'AsselerKlaus BacherKen KersemansPiet OstKarel DecaesteckerPieter DeseyneValerie Fonteyne et al.

A1 Journal Article in JOURNAL OF NUCLEAR MEDICINE

TMS dosage influences the change in dopamine

Robrecht DockxKathelijne PeremansDimitri De BundelAnn Van EeckhoutLise VlerickIngeborgh PolisNick Van LaekenGlenn PauwelynIngeborg GoethalsAndre Dobbeleire et al.

The ambiguity of the SERT during aHF-rTMS protocols

Robrecht DockxKathelijne PeremansDimitri De BundelAnn Van EeckhoutLise VlerickIngeborgh PolisNick Van LaekenGlenn PauwelynIngeborg GoethalsFilip De Vos et al.

2018

Evaluation and preliminary radiation dosimetry of [18F]PSMA-11 for PET imaging of prostate cancer

Sarah PironKathia De ManNick Van LaekenYves D'AsselerKen KersemansPiet OstKarel DecaesteckerPieter DeseyneValerie FonteyneNicolaas Lumen et al.

PET-imaging in depression and antidepressant therapies : focus on the serotonin system and the cerebral glucose metabolism

Nick Van LaekenFilip De VosChristian VanhoveIngeborg Goethals

Regional alterations of cerebral [18F]FDG metabolism in the chronic unpredictable mild stress- and the repeated corticosterone depression model in rats

Nick Van LaekenGlenn PauwelynRobrecht DockxBenedicte DescampsBoudewijn BransKathelijne PeremansChris BaekenIngeborg GoethalsChristian VanhoveFilip De Vos

A1 Journal Article in JOURNAL OF NEURAL TRANSMISSION

The signature of the serotonin system in the chronic corticosterone depression mode : a study with (18F)MPPF, (18F)altaserin and (11C)DASB

Glenn PauwelynNick Van LaekenRobrecht DockxJeroen VerhoevenBenedicte DescampsKen KersemansKathelijne PeremansChris BaekenIngeborg GoethalsChristian Vanhove et al.

The signature of the serotonin system in the chronic corticosterone depression model : a study with [18F]MPPF, [18F]altanserin and [11C]DASB

Glenn PauwelynNick Van LaekenJeroen VerhoevenFilip De VosKathelijne PeremansRobrecht DockxChris BaekenBenedicte DescampsChristian VanhoveKen Kersemans et al.

A2 Journal Article in NEUROPSYCHIATRY

2017

Accurate external localization of the left frontal cortex in dogs by using pointer based frameless neuronavigation

Robrecht DockxKathelijne PeremansRomain DupratLise VlerickNick Van LaekenJimmy SaundersIngeborgh PolisFilip De VosChris Baeken

A1 Journal Article in PEERJ

Anaesthesia, not number of sessions, influences the magnitude and duration of an aHF-rTMS in dogs

Robrecht DockxKathelijne PeremansLise VlerickNick Van LaekenJimmy SaundersIngeborgh PolisFilip De VosChris Baeken

A1 Journal Article in PLOS ONE

Estimation of the optimal dosing regimen of escitalopram in dogs : a dose occupancy study with [11C]DASB

Olivia TaylorNick Van LaekenIngeborgh PolisRobrecht DockxLise VlerickAndré DobbeleirIngeborg GoethalsJimmy SaundersNele SadonesChris Baeken et al.

A1 Journal Article in PLOS ONE

The effect of repeated corticosterone injections on the 5HT1a & 5HT2a receptor density and depression-like behaviour in male rats

Glenn PauwelynNick Van LaekenJeroen VerhoevenKen KersemansBenedicte DescampsChris BaekenChristian VanhoveFilip De Vos

2016

In vivo evaluation of blood based and reference tissue based PET quantifications of [11C]DASB in the canine brain

Nick Van LaekenOlivia TaylorIngeborgh PolisSara NeytKen KersemansAndre DobbeleirJimmy SaundersIngeborg GoethalsKathelijne PeremansFilip De Vos

A1 Journal Article in PLOS ONE

The effect of repeated corticsterone injections on 5HT2a receptor density, cerebral glucose consumption and depression-like behaviour in rat brain : a pilot study

Glenn PauwelynNick Van LaekenMarlies VanthornoutKen KersemansBenedicte DescampsChris BaekenChristian VanhoveFilip De Vos

2015

In vivo quantification of the [11C]-DASB binding in the normal canine brain using Positron Emission Tomography

Olivia TaylorNick Van LaekenFilip De VosIngeborgh PolisTim BosmansIngeborg GoethalsEric AchtenAndré DobbeleirEva VandermeulenChris Baeken et al.

In vivo quantification of the [11C]DASB binding in the normal canine brain using positron emission tomography

Olivia TaylorNick Van LaekenFilip De VosIngeborgh PolisTim BosmansIngeborg GoethalsEric AchtenAndré DobbeleirEva VandermeulenChris Baeken et al.

A1 Journal Article in BMC VETERINARY RESEARCH

Validation of neuronavigation as a tool to improve coil positioning in rodent rTMS studies

Nick Van LaekenRomain DupratBenedicte DescampsChristian VanhoveGiorgio HallaertKarel DeprezIngeborg GoethalsChris BaekenFilip De Vos

2014

Correlation between individual differences in striatal dopamine and in visual consciousness

Filip Van OpstalNick Van LaekenTom VergutsJean-Philippe van DijckFilip De VosIngeborg GoethalsWim Fias

A1 Journal Article in CURRENT BIOLOGY

Evaluation of the PET-radioligand 11C DASB in dogs

Nick Van LaekenOlivia TaylorAndré DobbeleireIngeborgh PolisEva VandermeulenTim BosmansSara NeytKen KersemansIngeborg GoethalsKathelijne Peremans et al.

Neuronavigation as a potential tool to perform neurostimulation in the rat brain

Nick Van LaekenRomain DupratBenedicte DescampsChristian VanhoveIngeborg GoethalsChris Baeken

2013

Improved HPLC purification strategy for [11C]raclopride and [11C]DASB leading to high radiochemical yields and more practical high quality radiopharmaceutical formulations

Nick Van LaekenKen KersemansDieter De MeestereIngeborg GoethalsFilip De Vos

A1 Journal Article in APPLIED RADIATION AND ISOTOPES

Radiochemistry devoted to the production of monoamine oxidase (MAO-A and MAO-B) ligands for brain imaging with positron emission tomography

Ken KersemansNick Van LaekenFilip De Vos

A1 Journal Article in JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

The need for in vivo experiments to investigate possible chaperone effects of pharmacological compounds

Nick Van LaekenKathleen Van CraenenbroeckJeroen VerhoevenChristian VanhoveFilip De Vos

Threshold for visual awareness is associated with striatal dopamine D2 receptor binding

Filip Van OpstalTom VergutsNick Van LaekenFilip De VosIngeborg GoethalsWim Fias

Visualization of the effect of reboxetine on the noradrenaline concentration in the rat brain using 11C-yohimbine

Vincent KeeremanNick Van LaekenStefaan VandenbergheChristian VanhoveFilip De VosRobrecht Raedt

2012

Simplified analytical HPLC purification of [11C]-raclopride

Nick Van LaekenKen KersemansFilip De Vos