Manage settings
MENU
About this site
In het Nederlands
Home
Researchers
Projects
Organisations
Publications
Infrastructure
Contact
Research Explorer
Your browser does not support JavaScript or JavaScript is not enabled. Without JavaScript some functions of this webapplication may be disabled or cause error messages. To enable JavaScript, please consult the manual of your browser or contact your system administrator.
Researcher
Nan Zhang
Profile
Projects
Publications
Activities
Awards & Distinctions
126
Results
2024
MZB1-expressing cells are essential for local immunoglobulin production in chronic rhinosinusitis with nasal polyps
Yanran Huang
Zhaofeng Xu
Gabriële Holtappels
Yang Shen
Thibaut Van Zele
Weiping Wen
Luo Zhang
Nan Zhang
Claus Bachert
A1
Journal Article
in
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
2024
The alphaherpesvirus gE/gI glycoprotein complex and proteases jointly orchestrate invasion across the host’s upper respiratory epithelial barrier
Eline Van Crombrugge
Xiaolei Ren
Sarah Glorieux
Ines Zarak
Wim Van Den Broeck
Claus Bachert
Nan Zhang
Thibaut Van Zele
D. Kim
G. A. Smith
et al.
A1
Journal Article
in
MBIO
2024
2023
Effect of Haemophilus influenzae, Streptococcus pneumoniae and influenza vaccinations on infections, immune response and asthma control in preschool children with asthma
Ya‐dong Gao
Paraskevi Xepapadaki
Yan‐wen Cui
Barbara Stanic
Debbie J. Maurer
Claus Bachert
Nan Zhang
Susetta Finotto
Maciej Chalubinski
Heikki Lukkarinen
et al.
A1
Journal Article
in
ALLERGY
2023
Effects of biologics treatment in type 2-high chronic rhinosinusitis with nasal polyp patients
Sharon Van Nevel
Tim Meese
Gabriële Holtappels
Natalie De Ruyck
Stijn Vanhee
Nan Zhang
Filip Van Nieuwerburgh
Claus Bachert
C3
Conference
2023
Endotypes of chronic rhinosinusitis based on inflammatory and remodeling factors
Xiangdong Wang
Yutong Sima
Yan Zhao
Nan Zhang
Ming Zheng
Kun Du
Min Wang
Yue Wang
Yun Hao
Ying Li
et al.
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2023
Innovative treatments for severe uncontrolled chronic rhinosinusitis with nasal polyps
Yanran Huang
Nan Zhang
Claus Bachert
A1
Journal Article
in
EXPERT REVIEW OF CLINICAL IMMUNOLOGY
2023
Olfaction in nasal polyp patients after Reboot surgery : an endotype-based prospective study
Sara Costa Gomes
Tim Delemarre
Gabriële Holtappels
Thibaut Van Zele
Lara Derycke
Ellen Bonne
Anne-Sophie Eeckels
Nan Zhang
Richard Louis Voegels
Claus Bachert
A1
Journal Article
in
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
2023
The multi-omics single-cell landscape of sinus mucosa in uncontrolled severe chronic rhinosinusitis with nasal polyps
Zhaofeng Xu
Yanran Huang
Tim Meese
Sharon Van Nevel
Gabriële Holtappels
Stijn Vanhee
Barbara M. Bröker
Zhengqi Li
Ellen De Meester
Natalie De Ruyck
et al.
A1
Journal Article
in
CLINICAL IMMUNOLOGY
2023
2022
A diagnostic model for predicting type 2 nasal polyps using biomarkers in nasal secretion
Zaichuan Wang
Qiqi Wang
Su Duan
Yuling Zhang
Limin Zhao
Shujian Zhang
Liusiqi Hao
Yan Li
Xiangdong Wang
Chenshuo Wang
et al.
A1
Journal Article
in
FRONTIERS IN IMMUNOLOGY
2022
Advances in chronic rhinosinusitis in 2020 and 2021
Zhaofeng Xu
Yanran Huang
Tim Delemarre
Carlo Cavaliere
Nan Zhang
Claus Bachert
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2022
IL-10 family cytokines in chronic rhinosinusitis with nasal polyps : from experiments to the clinic
Lijia Xuan
Nan Zhang
Xiangdong Wang
Luo Zhang
Claus Bachert
A1
Journal Article
in
FRONTIERS IN IMMUNOLOGY
2022
Local immunoglobulin E in nasal polyps : role and modulation
Yang Shen
Nan Zhang
Yucheng Yang
Suling Hong
Claus Bachert
A1
Journal Article
in
FRONTIERS IN IMMUNOLOGY
2022
Mepolizumab and benralizumab reduce eosinophilic inflammation in nasal polyposis, do neutrophils take over?
Tim Delemarre
Elien Gevaert
Gabriële Holtappels
Nan Zhang
Hans Nauwynck
Claus Bachert
C3
Conference
2022
Physical activity in asthma control and its immune modulatory effect in asthmatic preschoolers
Debbie J. Maurer
Chengyao Liu
Paraskevi Xepapadaki
Barbara Stanic
Claus Bachert
Susetta Finotto
Ya‐Dong Gao
Anna Graser
Tuomas Jartti
Walter Kistler
et al.
A1
Journal Article
in
ALLERGY
2022
Reboot surgery for chronic rhinosinusitis with nasal polyposis : recurrence and smell kinetics
Sara Costa Gomes
Carlo Cavaliere
Simonetta Masieri
Thibaut Van Zele
Philippe Gevaert
Gabriële Holtappels
Nan Zhang
Pathmanaban Ramasamy
Richard Louis Voegels
Claus Bachert
A1
Journal Article
in
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
2022
Seasonal distribution of inhaled allergens in allergic asthma patients with or without allergic rhinitis
Ruxian Tian
Yujuan Yang
Liping Liu
Yuemei Sun
Ningbo Tang
Yu Zhang
Nan Zhang
Xicheng Song
Claus Bachert
A1
Journal Article
in
CHINESE MEDICAL JOURNAL
2022
The development of the mucosal concept in chronic rhinosinusitis and its clinical implications
Yanran Huang
Nan Zhang
Zhaofeng Xu
L Zhang
Claus Bachert
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
2022
2021
A substantial neutrophilic inflammation as regular part of severe type 2 chronic rhinosinusitis with nasal polyps
Tim Delemarre
Gabriële Holtappels
Natalie De Ruyck
Nan Zhang
Hans Nauwynck
Claus Bachert
Elien Gevaert
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2021
Clinical correlates of rhinovirus infection in preschool asthma
Tuomas Jartti
Unna Liimatainen
Paraskevi Xepapadaki
Tero Vahlberg
Claus Bachert
Susetta Finotto
Marek L. Kowalski
Anna Sobanska
Heikki Lukkarinen
Maria Pasioti
et al.
A1
Journal Article
in
ALLERGY
2021
Involvement of the extracellular matrix proteins periostin and tenascin C in nasal polyp remodeling by regulating the expression of MMPs
Kun Du
Min Wang
Nan Zhang
Pei Yu
Ping Wang
Ying Li
Xiangdong Wang
Luo Zhang
Claus Bachert
A1
Journal Article
in
CLINICAL AND TRANSLATIONAL ALLERGY
2021
Neutrophils affect IL-33 processing in response to the respiratory allergen Alternaria alternata
Sharon Van Nevel
Judith van Ovost
Gabriële Holtappels
Natalie De Ruyck
Nan Zhang
Harald Braun
Tania Maes
Claus Bachert
Olga Krysko
A1
Journal Article
in
FRONTIERS IN IMMUNOLOGY
2021
Physiology and pathology of eosinophils : recent developments summary of the Focus Workshop organized by DGAKI
Harald Renz
Claus Bachert
Claudia Berek
Eckard Hamelmann
Francesca Levi-Schaffer
Ulrike Raap
Hans-Uwe Simon
Sabine Ploetz
Christian Taube
Peter Valent
et al.
A1
Journal Article
in
SCANDINAVIAN JOURNAL OF IMMUNOLOGY
2021
Regulated on activation, normal T cell expressed and secreted (RANTES) drives the resolution of allergic asthma
Nina Li
Hoomann Mirzakhani
Alexander Kiefer
Julia Koelle
Tytti Vuorinen
Manfred Rauh
Zuqin Yang
Susanne Krammer
Paraskevi Xepapadaki
Anna Lewandowska-Polak
et al.
A1
Journal Article
in
ISCIENCE
2021
2020
Biologics for chronic rhinosinusitis with nasal polyps
Claus Bachert
Nan Zhang
Carlo Cavaliere
Wen Weiping Wen Weiping
Elien Gevaert
Olga Krysko
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2020
Charcot-Leyden crystals promote neutrophilic inflammation in patients with nasal polyposis
Elien Gevaert
Tim Delemarre
Joyceline De Volder
Nan Zhang
Gabriële Holtappels
Natalie De Ruyck
Emma Persson
Ines Heyndrickx
Kenneth Verstraete
Helena Catharine Aegerter
et al.
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2020
Endotypes of chronic rhinosinusitis with nasal polyps : pathology and possible therapeutic implications
Claus Bachert
Brad Marple
Werner Hosemann
Carlo Cavaliere
Weiping Wen
Nan Zhang
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
2020
Evolution of airway inflammation in preschoolers with asthma : results of a two-year longitudinal study
Paraskevi Xepapadaki
Paraskevi Korovessi
Claus Bachert
Susetta Finotto
Tuomas Jartti
John Lakoumentas
Marek L. Kowalski
Anna Lewandowska-Polak
Heikki Lukkarinen
Nan Zhang
et al.
A1
Journal Article
in
JOURNAL OF CLINICAL MEDICINE
2020
Evolution of airway inflammation in preschoolers with asthma-results of a two-year longitudinal study
P. Xepapadaki
P. Korovessi
Claus Bachert
S. Finotto
T. Jartti
J. Lakoumentas
M. L. Kowalski
A. Lewandowska-Polak
H. Lukkarinen
Nan Zhang
et al.
C3
Conference
2020
Impaired small airway function in non-asthmatic chronic rhinosinusitis with nasal polyps
Kun Du
Ming Zheng
Yan Zhao
Wenbin Xu
Yun Hao
Yue Wang
Jinming Zhao
Nan Zhang
Xiangdong Wang
Luo Zhang
et al.
A1
Journal Article
in
CLINICAL AND EXPERIMENTAL ALLERGY
2020
Perspective : COVID-19, implications of nasal diseases and consequences for their management
Li Jian
Wei Yi
Nan Zhang
Weiping Wen
Olga Krysko
Woo-Jung Song
Claus Bachert
Editorial material
2020
Stability of regulatory T cells in T helper 2-biased allergic airway diseases
Feng Lan
Nan Zhang
Claus Bachert
Luo Zhang
A1
Journal Article
in
ALLERGY
2020
Staphylococcus aureus and its IgE-inducing enterotoxins in asthma : current knowledge
Claus Bachert
Marc Humbert
Nicola A. Hanania
Nan Zhang
Stephen Holgate
Roland Buhl
Barbara M. Broeker
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2020
The role of regulated on activation, normal T cell expressed and secreted (RANTES) in allergic asthma
N. Li
J. Koelle
A. Kiefer
P. Xepapadaki
M. L. Kowalski
Claus Bachert
T. Jartti
T. Vuorinen
A. Lewandowska-Polak
Nan Zhang
et al.
C3
Conference
2020
Type 2 inflammation in chronic rhinosinusitis without nasal polyps : another relevant endotype
Tim Delemarre
Gabriële Holtappels
Natalie De Ruyck
Nan Zhang
Hans Nauwynck
Claus Bachert
Elien Gevaert
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2020
2019
Biologics for the treatment of chronic rhinosinusitis with nasal polyps : state of the art
Lei Ren
Nan Zhang
Luo Zhang
Claus Bachert
A1
Journal Article
in
WORLD ALLERGY ORGANIZATION JOURNAL
2019
Biologika in der Behandlung der chronischen Rhinosinusitis mit Nasenpolypen : Aktueller Stand
Nan Zhang
Claus Bachert
A1
Journal Article
in
ALLERGOLOGIE
2019
Comparison of a new Skin Prick Test Tape with the conventional skin prick test
Zhengpeng Gong
Zhijie Yang
Ran Wu
Huiping Ye
Min Jia
Nan Zhang
Claus Bachert
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2019
Cross-talk between TH2 and TH17 pathways in patients with chronic rhinosinusitis with nasal polyps
Min Wang
Nan Zhang
Ming Zheng
Ying Li
Lingling Meng
Yu Ruan
Jinbo Han
Na Zhao
Xiangdong Wang
Luo Zhang
et al.
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2019
Development and characterization of DNAzyme candidates demonstrating significant efficiency against human rhinoviruses
Daniel P Potaczek
Sebastian D Unger
Nan Zhang
Styliani Taka
Sven Michel
Nesibe Akdağ
Feng Lan
Markus Helfer
Christoph Hudemann
Markus Eickmann
et al.
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2019
Development of antirhinoviral DNAzymes for effective prevention of asthma exacerbations
Daniel P Potaczek
Sebastian D Unger
Nan Zhang
Styliani Taka
Sven Michel
Nesibe Akdag
Feng Lan
Markus Helfer
Christoph Hudemann
Markus Eickmann
et al.
C3
Conference
2019
IFN-λ1 enhances Staphylococcus aureus clearance in healthy nasal mucosa but not in nasal polyps
Feng Lan
Hua Zhong
Nan Zhang
Sebastian L Johnston
Weiping Wen
Nikos Papadopoulos
Luo Zhang
Claus Bachert
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2019
Medical algorithm : diagnosis and treatment of chronic rhinosinusitis
Claus Bachert
Nan Zhang
Editorial material
2019
Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in IL-5-positive chronic rhinosinusitis with nasal polyps
Y Zhang
Lara Derycke
Gabriële Holtappels
XD Wang
L Zhang
Claus Bachert
Nan Zhang
A1
Journal Article
in
ALLERGY
2019
The effect of fine particulate matter on the inflammatory responses in human upper airway mucosa
Hui Qing
Xiangdong Wang
Nan Zhang
Kaili Zheng
Kun Du
Ming Zheng
Ying Li
Yu Chang
Luo Zhang
Claus Bachert
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2019
2018
Contribution of repeated infections in asthma persistence from preschool to school age : design and characteristics of the PreDicta cohort
Paraskevi Xepapadaki
Claus Bachert
Susetta Finotto
Tuomas Jartti
George N Konstantinou
Alexander Kiefer
Marek Kowalski
Anna Lewandowska-Polak
Heikki Lukkarinen
Eirini Roumpedaki
et al.
A1
Journal Article
in
PEDIATRIC ALLERGY AND IMMUNOLOGY
2018
Development and characterization of effective DNAzymes against human rhinoviruses
DP Potaczek
SD Unger
Nan Zhang
S Taka
S Michel
N Akdag
Feng Lan
M Helfer
C Hudemann
M Eickmann
et al.
C3
Conference
2018
Endotype-driven care pathways in patients with chronic rhinosinusitis
Claus Bachert
Nan Zhang
Peter W Hellings
Jean Bousquet
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2018
Highlights of eosinophilic chronic rhinosinusitis with nasal polyps in definition, prognosis, and advancement
Hongfei Lou
Nan Zhang
Claus Bachert
Luo Zhang
A1
Journal Article
in
INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY
2018
Immunomodulatory effect of Bifidobacterium breve on experimental allergic rhinitis in BALB/c mice
Jianjun Ren
Yu Zhao
Shi Huang
Dan Lv
Fengling Yang
Lin Lou
Yongbo Zheng
Jie Zhang
Shixi Liu
Nan Zhang
et al.
A1
Journal Article
in
EXPERIMENTAL AND THERAPEUTIC MEDICINE
2018
Multivariate analysis of inflammatory endotypes in recurrent nasal polyposis in a Chinese population
Bo Wei
Feng Liu
Jie Zhang
Yafeng Liu
Jintao Du
Shixi Liu
Nan Zhang
Claus Bachert
Juan Meng
A1
Journal Article
in
RHINOLOGY
2018
Rhinovirus species-specific antibodies differentially reflect clinical outcomes in health and asthma
Spyridon Megremis
Katarzyna Niespodziana
Clarissa Cabauatan
Paraskevi Xepapadaki
Marek L Kowalski
Tuomas Jartti
Claus Bachert
Susetta Finotto
Peter West
Sofia Stamataki
et al.
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2018
Staphylococcus aureus controls interleukin-5 release in upper airway inflammation
Claus Bachert
Gabriële Holtappels
Maia Merabishvili
T Meyer
A Murr
Nan Zhang
Koen Van Crombruggen
Elien Gevaert
U Völker
BM Bröker
et al.
A1
Journal Article
in
JOURNAL OF PROTEOMICS
2018
Staphylococcus aureus enhances the tight junction barrier integrity in healthy nasal tissue, but not in nasal polyps
Can Altunbulakli
Rita Costa
Feng Lan
Nan Zhang
Mubeccel Akdis
Claus Bachert
Cezmi A Akdis
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2018
Staphylococcus aureus induces a mucosal type 2 immune response via epithelial cell-derived cytokines
Feng Lan
Nan Zhang
Gabriële Holtappels
Natalie De Ruyck
Olga Krysko
Koen Van Crombruggen
Harald Braun
Sebastian L Johnston
Nikos G Papadopoulos
Luo Zhang
et al.
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2018
Th17 response against mucosal infection in persistent upper airways is partially impaired in viruses and bacteria coinfection condition
F Lan
L Zhang
Nan Zhang
Claus Bachert
C3
Conference
2018
2017
Characterization of human and Staphylococcus aureus proteins in respiratory mucosa by in vivo- and immunoproteomics
Frank Schmidt
Tanja Meyer
Nandakumar Sundaramoorthy
Stephan Michalik
Kristin Surmann
Maren Depke
Vishnu Dhople
Manuela Gesell Salazar
Gabriële Holtappels
Nan Zhang
et al.
A1
Journal Article
in
JOURNAL OF PROTEOMICS
2017
Chronic rhinosinusitis in Asia
Yuan Zhang
Elien Gevaert
Hongfei Lou
Xiangdong Wang
Luo Zhang
Claus Bachert
Nan Zhang
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2017
Extracellular eosinophilic traps in association with Staphylococcus aureus at the site of epithelial barrier defects in patients with severe airway inflammation
Elien Gevaert
Nan Zhang
Olga Krysko
Feng Lan
Gabriële Holtappels
Natalie De Ruyck
Hans Nauwynck
Shida Yousefi
Hans-Uwe Simon
Claus Bachert
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2017
Nasal polyposis and asthma : a mechanistic paradigm focusing on Staphylococcus aureus
Claus Bachert
Nan Zhang
Olga Krysko
Koen Van Crombruggen
Elien Gevaert
Bookchapter
in
The nose and sinuses in respiratory disorders
2017
Non-allergic rhinitis : position paper of the European Academy of Allergy and Clinical Immunology
PW Hellings
L Klimek
C Cingi
I Agache
C Akdis
Claus Bachert
J Bousquet
P Demoly
Philippe Gevaert
V Hox
et al.
A1
Journal Article
in
ALLERGY
2017
Programmed cell death-1 expression correlates with disease severity and IL-5 in chronic rhinosinusitis with nasal polyps
I Kortekaas Krohn
S Bobic
J Dooley
Feng Lan
Nan Zhang
Claus Bachert
B Steelant
DM Bullens
A Liston
JL Ceuppens
et al.
A1
Journal Article
in
ALLERGY
2017
2016
An increased prevalence of self-reported allergic rhinitis in major Chinese cities from 2005 to 2011
XD Wang
M Zheng
HF Lou
CS Wang
Y Zhang
MY Bo
SQ Ge
Nan Zhang
L Zhang
Claus Bachert
A1
Journal Article
in
ALLERGY
2016
Barrier function of the nasal mucosa in health and type-2 biased airway diseases
Nan Zhang
Koen Van Crombruggen
Elien Gevaert
Claus Bachert
A1
Journal Article
in
ALLERGY
2016
Cellular phenotyping of chronic rhinosinusitis with nasal polyps
Hongfei Lou
Yifan Meng
Yingshi Piao
Nan Zhang
Claus Bachert
Chengshuo Wang
Luo Zhang
A1
Journal Article
in
RHINOLOGY
2016
Diversity of TH cytokine profiles in patients with chronic rhinosinusitis : a multicenter study in Europe, Asia, and Oceania
Xiangdong Wang
Nan Zhang
Mingyu Bo
Gabriële Holtappels
Ming Zheng
Hongfei Lou
Hong Wang
Luo Zhang
Claus Bachert
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2016
Th2 biased upper airway inflammation is associated with an impaired response to viral infection with Herpes simplex virus 1
Feng Lan
Xiang Dong Wane
Hans Nauwynck
Gabriële Holtappels
Luo Zhang
Sebastian L Johnston
Nikolaos G Papadopoulos
Claus Bachert
Nan Zhang
A1
Journal Article
in
RHINOLOGY
2016
The role of viruses and Staphylococcus aureus in propagating a Th2 response in human nasal polyps
Feng Lan
Claus Bachert
Nan Zhang
Dissertation
2016
Viruses and bacteria in Th2-biased allergic airway disease
F Lan
Nan Zhang
Elien Gevaert
L Zhang
Claus Bachert
A1
Journal Article
in
ALLERGY
2016
2015
Allergen-induced asthmatic responses modified by a GATA3-specific DNAzyme
Norbert Krug
Jens M Hohlfeld
Anne-Marie Kirsten
Oliver Kornmann
Kai M Beeh
Dominik Kappeler
Stephanie Korn
Stanislav Ignatenko
Wolfgang Timmer
Cordelia Rogon
et al.
A1
Journal Article
in
NEW ENGLAND JOURNAL OF MEDICINE
2015
Association of mucosal organisms with patterns of inflammation in chronic rhinosinusitis
Thanit Chalermwatanachai
Nan Zhang
Gabriële Holtappels
Claus Bachert
A1
Journal Article
in
PLOS ONE
2015
Association of periostin expression with eosinophilic inflammation in nasal polyps
Min Wang
Xiangdong Wang
Nan Zhang
Hong Wang
Ying Li
Erzhong Fan
Liang Zhang
Luo Zhang
Claus Bachert
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2015
Differential expression and release of activin A and follistatin in chronic rhinosinusitis with and without nasal polyps
Yucheng Yang
Nan Zhang
Koen Van Crombruggen
Feng Lan
Guohua Hu
Suling Hong
Claus Bachert
A1
Journal Article
in
PLOS ONE
2015
Effects of Bifidobacterium breve feeding strategy and delivery modes on experimental allergic rhinitis mice
Jian-Jun Ren
Zhao Yu
Feng-Ling Yang
Dan Lv
Shi Hung
Jie Zhang
Ping Lin
Shi-Xi Liu
Nan Zhang
Claus Bachert
A1
Journal Article
in
PLOS ONE
2015
Staphyloccoccus aureus induces a Th2 response via TSLP and IL-33 release in human airway mucosa
Feng Lan
Nan Zhang
Gabriële Holtappels
Natalie De Ruyck
Nikolaos G Papadopoulos
Sebastian L Johnston
Claus Bachert
C3
Conference
2015
Staphylococcus aureus enterotoxin B induces airway epithelial barrier dysfunction in vitro
B Steelant
Feng Lan
Nan Zhang
S Seys
I Kortekaas Krohn
JL Ceuppens
Claus Bachert
C Akdis
PW Hellings
C3
Conference
2015
Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in chronic rhinosinusitis with nasal polyps
Yu Zhang
Lara Derycke
Luo Zhang
Gabriële Holtappels
Xiangdong Wang
Nan Zhang
Claus Bachert
C3
Conference
2015
The clinical significance of the pollen calendar of the Western Thrace/northeast Greece region in allergic rhinitis
Michael Katotomichelakis
Christos Nikolaidis
Michael Makris
Nan Zhang
Xenophon Aggelides
Theodoros C Constantinidis
Claus Bachert
Vassilios Danielides
A1
Journal Article
in
INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY
2015
2014
Different regulation of activin A and follistatin in chronic rhinosinusitis with or without nasal polyps
Y Yang
Nan Zhang
F Lan
Koen Van Crombruggen
G Hu
S Hong
Claus Bachert
C3
Conference
2014
Staphyloccoccus aureus elicit epithelial cell-derived cytokine productions in human nasal tissue
F Lan
Nan Zhang
DX Wang
Olga Krysko
Gabriële Holtappels
NG Papadopoulos
SL Johnston
Claus Bachert
C3
Conference
2014
Suppression of cytokine release by fluticasone furoate vs. mometasone furoate in human nasal tissue ex-vivo
Nan Zhang
Koen Van Crombruggen
Gabriële Holtappels
Feng Lan
Michail Katotomichelakis
Luo Zhang
Petra Högger
Claus Bachert
A1
Journal Article
in
PLOS ONE
2014
The effects of smoking on quality of life recovery after surgery for chronic rhinosinusitis
Michael Katotomichelakis
Efthimios Simopoulos
Gregory Tripsianis
Nan Zhang
Gerasimos Danielides
Panagiota Gouma
Claus Bachert
Vassilios Danielides
A1
Journal Article
in
RHINOLOGY
2014
Transforming growth factor-beta 1 pathways in inflammatory airway diseases
Y Yang
Nan Zhang
F Lan
Koen Van Crombruggen
L Fang
G Hu
S Hong
Claus Bachert
A1
Journal Article
in
ALLERGY
2014
2013
Allergic fungal rhinosinusitis: more than a fungal disease?
TINEKE DUTRE
Surayie Al Dousary
Nan Zhang
Claus Bachert
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2013
Damage‑associated molecular patterns and their receptors in upper airway pathologies
Koen Van Crombruggen
Fenila Jacob
Nan Zhang
Claus Bachert
A1
Journal Article
in
CELLULAR AND MOLECULAR LIFE SCIENCES
2013
Forkhead box P3 in human airway regulatory T cells is regulated by suppressor of cytokine signaling
F Lan
Nan Zhang
J Zhang
Olga Krysko
Q Zhang
J Xian
Lara Derycke
Y Qi
K Li
S Liu
et al.
C3
Conference
2013
Forkhead box protein 3 in human nasal polyp regulatory T cells is regulated by the protein suppressor of cytokine signaling 3
Feng Lan
Nan Zhang
Jie Zhang
Olga Krysko
Quanbo Zhang
Junming Xian
Lara Derycke
Yanyu Qi
Kai Li
Shixi Liu
et al.
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2013
Inflammatory patterns in upper airway disease in the same geographical area may change over time
Michail Katotomichelakis
Pongsakorn Tantilipikorn
Gabriële Holtappels
Natalie De Ruyck
Feng Lan
Thibaut Van Zele
Soranart Muangsomboon
Perapun Jareonchasri
Chaweewan Bunnag
Vassilios Danielides
et al.
A1
Journal Article
in
AMERICAN JOURNAL OF RHINOLOGY & ALLERGY
2013
Olfactory dysfunction and asthma as risk factors for poor quality of life in upper airway diseases
Michael Katotomichelakis
Efthimios Simopoulos
Nan Zhang
Gregory Tripsianis
Gerasimos Danielides
Miltos Livaditis
Claus Bachert
Vassilios Danielides
A1
Journal Article
in
AMERICAN JOURNAL OF RHINOLOGY & ALLERGY
2013
The development of nasal polyp disease involves early nasal mucosal inflammation and remodelling
Juan Meng
Peng Zhou
Yafeng Liu
Xuelian Yi
Shixi Liu
Gabriële Holtappels
Claus Bachert
Nan Zhang
A1
Journal Article
in
PLOS ONE
2013
The pathogenesis of CRS : an update
Claus Bachert
Nada Al Bahrani
Surayie Al Dousary
Koen Van Crombruggen
Olga Krysko
Claudina Perez Novo
Nan Zhang
A2
Journal Article
in
CURRENT OTORHINOLARYNGOLOGY REPORTS
2013
Uncontrolled allergic rhinitis and chronic rhinosinusitis: where do we stand today?
pW Hellings
WJ Fokkens
C Akdis
Claus Bachert
C Cingi
D Dietz de Loos
Philippe Gevaert
V Hox
L Kalogjera
V Lund
et al.
A1
Journal Article
in
ALLERGY
2013
2012
A herbal composition of Scutellaria baicalensis and Eleutherococcus senticosus shows potent anti-inflammatory effects in an ex vivo human mucosal tissue model
Nan Zhang
Koen Van Crombruggen
Gabriële Holtappels
Claus Bachert
A1
Journal Article
in
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
2012
Chronic rhinosinusitis and asthma: novel understanding of the role of IgE 'above atopy'
Claus Bachert
Nan Zhang
A1
Journal Article
in
JOURNAL OF INTERNAL MEDICINE
2012
Chronic rhinosinusitis: from one disease to different phenotypes
Claus Bachert
Nan Zhang
Thibaut Van Zele
Philippe Gevaert
A1
Journal Article
in
PEDIATRIC ALLERGY AND IMMUNOLOGY
2012
Herpes simplex virus type 1 infection facilitates invasion of Staphylococcus aureus into the nasal mucosa and nasal polyp tissue
XiangDong Wang
Nan Zhang
Sarah Glorieux
Gabriële Holtappels
Mario Vaneechoutte
Olga Krysko
Luo Zhang
DeMin Han
Hans Nauwynck
Claus Bachert
A1
Journal Article
in
PLOS ONE
2012
IL-17A as a regulator of neutrophil survival in nasal polyp disease of patients with and without cystic fibrosis
Lara Derycke
Nan Zhang
Gabriële Holtappels
TINEKE DUTRE
Claus Bachert
A1
Journal Article
in
JOURNAL OF CYSTIC FIBROSIS
2012
Specific IgE against Staphylococcus aureus enterotoxins: an independent risk factor for asthma
Claus Bachert
Kristel Van Steen
Nan Zhang
Gabriële Holtappels
Tom Cattaert
Bärbel Maus
Roland Buhl
Christian Taube
Stephanie Korn
Marek Kowalski
et al.
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2012
Transforming growth factor-beta1 in inflammatory airway disease: a key for understanding inflammation and remodeling
YC Yang
Nan Zhang
Koen Van Crombruggen
GH Hu
SL Hong
Claus Bachert
A1
Journal Article
in
ALLERGY
2012
2011
Alternatively activated macrophages and impaired phagocytosis of S-aureus in chronic rhinosinusitis
Olga Krysko
Gabriële Holtappels
Nan Zhang
Malgorzata Kubica
Kim Deswarte
Lara Derycke
Sofie Claeys
Hamida Hammad
Guy Brusselle
Peter Vandenabeele
et al.
A1
Journal Article
in
ALLERGY
2011
Assessment of sleep impairment in persistent allergic rhinitis patients using polysomnography
J Meng
J Xuan
X Qiao
X Li
S Liu
KF Lukat
Nan Zhang
Claus Bachert
A1
Journal Article
in
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
2011
Increased nasal IL-5 levels act as a predisposing factor of asthma in southern China reply
Claus Bachert
Nan Zhang
Gabriële Holtappels
Peter Tomassen
Shixi Liu
Ping Lin
Jean Bousquet
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2011
Mucosal tissue polyclonal IgE is functional in response to allergen and SEB
Nan Zhang
Gabriële Holtappels
Philippe Gevaert
Joke Patou
B Dhaliwal
Hannah Gould
Claus Bachert
A1
Journal Article
in
ALLERGY
2011
Pathogenesis of chronic rhinosinusitis: inflammation
Koen Van Crombruggen
Nan Zhang
Philippe Gevaert
Peter Tomassen
Claus Bachert
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2011
Pathophysiology of chronic rhinosinusitis
Peter Tomassen
Thibaut Van Zele
Nan Zhang
Claudina Perez Novo
NICHOLAS VAN BRUAENE
Philippe Gevaert
Claus Bachert
A2
Journal Article
in
PROCEEDINGS OF THE AMERICAN THORACIC SOCIETY
2011
The association between bacterial colonization and inflammatory pattern in Chinese chronic rhinosinusitis patients with nasal polyps
L Ba
Nan Zhang
J Meng
J Zhang
P Lin
P Zhou
S Liu
Claus Bachert
A1
Journal Article
in
ALLERGY
2011
2010
CRTH2 mediates the activation of human Th2 cells in response to PGD2 released from IgE/anti-IgE treated nasal polyp tissue
Claudina Perez Novo
Gabriële Holtappels
Shân L Vinall
Luzheng Xue
Nan Zhang
Claus Bachert
Roy Pettipher
A1
Journal Article
in
ALLERGY
2010
Expression of TGF, matrix metalloproteinases, and tissue inhibitors in Chinese chronic rhinosinusitis
Xiaoyuan Li
Juan Meng
Xiaoming Qiao
Yafeng Lui
Feng Liu
Nan Zhang
Jie Zhang
Gabriële Holtappels
Ba Luo
Peng Zhuo
et al.
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2010
Inflammatory profiles in nasal mucosa of patients with persistent vs intermittent allergic rhinitis
F Liu
J Zhang
Y Liu
Nan Zhang
Gabriële Holtappels
P Lin
S Liu
Claus Bachert
A1
Journal Article
in
ALLERGY
2010
Presence of IL-5 protein and IgE antibodies to staphylococcal enterotoxins in nasal polyps is associated with comorbid asthma
Claus Bachert
Nan Zhang
Gabriële Holtappels
Lizzy De Lobel
Paul Van Cauwenberge
ShiXi Liu
Ping Lin
Jean Bousquet
Kristel Van Steen
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2010
Remodeling and inflammation in Chinese versus white patients with chronic rhinosinusitis
Nan Zhang
Shixi Liu
Ping Lin
Xiaoyuan Li
NICHOLAS VAN BRUAENE
Jie Zhang
Thibaut Van Zele
Claus Bachert
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2010
Rhinosinusitis and asthma : a link for asthma severity
Claus Bachert
Sofie Claeys
Peter Tomassen
Thibaut Van Zele
Nan Zhang
A1
Journal Article
in
CURRENT ALLERGY AND ASTHMA REPORTS
2010
Staphylococcus aureus-derived superantigens in nasal polyp disease
Peter Tomassen
Thibaut Van Zele
Philippe Gevaert
Nan Zhang
Claudina Perez Novo
NICHOLAS VAN BRUAENE
Joke Patou
Claus Bachert
Bookchapter
in
Nasal polyposis : pathogenesis, medical and surgical treatment
2010
2009
Chronic rhinosinusitis with and without nasal polyps: what is the difference?
Wouter Huvenne
NICHOLAS VAN BRUAENE
Nan Zhang
Thibaut Van Zele
Joke Patou
Philippe Gevaert
Sofie Claeys
Paul Van Cauwenberge
Claus Bachert
A1
Journal Article
in
Current Allergy and Asthma Reports
2009
Detection of Staphylococcus aureus in nasal tissue with peptide nucleic acid-fluorescence in situ hybridization
Marie-Noelle Corriveau
Nan Zhang
Gabriële Holtappels
Nadine Van Roy
Claus Bachert
A1
Journal Article
in
AMERICAN JOURNAL OF RHINOLOGY & ALLERGY
2009
Important research questions in allergy and related diseases: 3-chronic rhinosinusitis and nasal polyposis - a GA(2)LEN study
Claus Bachert
NICHOLAS VAN BRUAENE
E Toskala
Nan Zhang
H Olze
G Scadding
CM Van Drunen
J Mullol
L Cardell
Philippe Gevaert
et al.
A1
Journal Article
in
ALLERGY
2009
The presence of Staphylococcus aureus is not equivalent to an immune reaction to it's enterotoxins
MN Corriveau
Nan Zhang
Claus Bachert
A1
Journal Article
in
ALLERGY
2009
2008
Different types of T-effector cells orchestrate mucosal inflammation in chronic sinus disease
Nan Zhang
Thibaut Van Zele
Claudina Perez Novo
NICHOLAS VAN BRUAENE
Gabriële Holtappels
Natalie De Ruyck
Paul Van Cauwenberge
Claus Bachert
A1
Journal Article
in
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
2008
Pilot study using doxycycline-releasing stents to ameliorate postoperative healing quality after sinus surgery
Wouter Huvenne
Nan Zhang
E Tijsma
B Hissong
J Huurdeman
G Holtappels
Sofie Claeys
Paul Van Cauwenberge
Hans Nelis
Tom Coenye
et al.
A1
Journal Article
in
Wound Repair and Regeneration
2008
Role of staphylococcal superantigens in upper airway disease
Claus Bachert
Nan Zhang
Joke Patou
Thibaut Van Zele
Philippe Gevaert
A1
Journal Article
in
CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY
2008
2007
Remodelling in nasal polyposis is independent of TH-cell polarisation
Nan Zhang
TV ZELE
Philippe Gevaert
Gabriële Holtappels
P VAN CAUWENBERGE
Claus Bachert
C3
Conference
2007
Role of Staphylococcal superantigens in airway disease
Claus Bachert
Philippe Gevaert
Nan Zhang
Thibaut Van Zele
Claudina Perez Novo
Bookchapter
in
Superantigens and superallergens
2007
Role of staphylococcal superantigens in airway disease: a review, part 2: S-aureus enterotoxins in AERD, asthma, early childhood wheezing and COPD
Claus Bachert
Nan Zhang
Philippe Gevaert
Thibaut Van Zele
Claudina Perez Novo
A1
Journal Article
in
ALLERGOLOGIE
2007
Staphylococcal superantigens in airway disease: a review, part 1: the role of S-aureus enterotoxins in allergic rhinitis and nasal polyps
Claus Bachert
Philippe Gevaert
Nan Zhang
Thibaut Van Zele
Claudina Perez Novo
A1
Journal Article
in
ALLERGOLOGIE
2007
Staphylococcus Aureus Enterotoxins as Immune Stimulants in Chronic Rhinosinusitis
Claus Bachert
Nan Zhang
Thibaut Van Zele
Philippe Gevaert
Joke Patou
Paul Van Cauwenberge
Bookchapter
in
Chronic Rhinosinusitis
2007
2006
Pattern of inflammation and impact of Staphylococcus aureus enterotoxins in nasal polyps from southern China
Nan Zhang
Gabriële Holtappels
Cindy Claeys
GQ HUANG
Paul Van Cauwenberge
Claus Bachert
A1
Journal Article
in
AMERICAN JOURNAL OF RHINOLOGY
2006
2005
An update on the impact of Staphylococcus aureus enterotoxins in chronic sinusitis with nasal polyposis
Nan Zhang
Philippe Gevaert
Thibaut Van Zele
Claudina Perez Novo
Joke Patou
Gabriële Holtappels
Paul Van Cauwenberge
Claus Bachert
A1
Journal Article
in
RHINOLOGY
2005