Research Explorer

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Researcher

Nan Zhang

104 Results

2021

A substantial neutrophilic inflammation as regular part of severe type 2 chronic rhinosinusitis with nasal polyps

Tim DelemarreGabriële HoltappelsNatalie De RuyckNan ZhangHans NauwynckClaus BachertElien Gevaert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Clinical correlates of rhinovirus infection in preschool asthma

Tuomas JarttiUnna LiimatainenParaskevi XepapadakiTero VahlbergClaus BachertSusetta FinottoMarek L. KowalskiAnna SobanskaHeikki LukkarinenMaria PasiotiTytti VuorinenNan ZhangTheodor ZimmermannNikolaos G. Papadopoulos

A1 Journal Article in ALLERGY

Physiology and pathology of eosinophils : recent developments summary of the Focus Workshop organized by DGAKI

Harald RenzClaus BachertClaudia BerekEckard HamelmannFrancesca Levi-SchafferUlrike RaapHans-Uwe SimonSabine PloetzChristian TaubePeter ValentDavid VoehringerThomas WerfelNan ZhangJohannes Ring

A1 Journal Article in SCANDINAVIAN JOURNAL OF IMMUNOLOGY

2020

Biologics for chronic rhinosinusitis with nasal polyps

Claus BachertNan ZhangCarlo CavaliereWen Weiping Wen WeipingElien GevaertOlga Krysko

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Charcot-Leyden crystals promote neutrophilic inflammation in patients with nasal polyposis

Elien GevaertTim DelemarreJoyceline De VolderNan ZhangGabriële HoltappelsNatalie De RuyckEmma PerssonInes HeyndrickxKenneth VerstraeteHelena Catharine AegerterHans NauwynckSavvas SavvidesBart LambrechtClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Evolution of airway inflammation in preschoolers with asthma : results of a two-year longitudinal study

Paraskevi XepapadakiParaskevi KorovessiClaus BachertSusetta FinottoTuomas JarttiJohn LakoumentasMarek L. KowalskiAnna Lewandowska-PolakHeikki LukkarinenNan ZhangTheodor ZimmermannNikolaos G. Papadopoulos

A1 Journal Article in JOURNAL OF CLINICAL MEDICINE

Evolution of airway inflammation in preschoolers with asthma-results of a two-year longitudinal study

P. XepapadakiP. KorovessiClaus BachertS. FinottoT. JarttiJ. LakoumentasM. L. KowalskiA. Lewandowska-PolakH. LukkarinenNan ZhangT. ZimmermannN. G. Papadopoulos

Impaired small airway function in non-asthmatic chronic rhinosinusitis with nasal polyps

Kun DuMing ZhengYan ZhaoWenbin XuYun HaoYue WangJinming ZhaoNan ZhangXiangdong WangLuo ZhangClaus Bachert

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Perspective : COVID-19, implications of nasal diseases and consequences for their management

Li JianWei YiNan ZhangWeiping WenOlga KryskoWoo-Jung SongClaus Bachert

Editorial material

Stability of regulatory T cells in T helper 2-biased allergic airway diseases

Feng LanNan ZhangClaus BachertLuo Zhang

A1 Journal Article in ALLERGY

Staphylococcus aureus and its IgE-inducing enterotoxins in asthma : current knowledge

Claus BachertMarc HumbertNicola A. HananiaNan ZhangStephen HolgateRoland BuhlBarbara M. Broeker

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

The role of regulated on activation, normal T cell expressed and secreted (RANTES) in allergic asthma

N. LiJ. KoelleA. KieferP. XepapadakiM. L. KowalskiClaus BachertT. JarttiT. VuorinenA. Lewandowska-PolakNan ZhangH. LukkarinenT. ZimmermannM. AkdisN. G. PapadopoulosS. Finotto

Type 2 inflammation in chronic rhinosinusitis without nasal polyps : another relevant endotype

Tim DelemarreGabriële HoltappelsNatalie De RuyckNan ZhangHans NauwynckClaus BachertElien Gevaert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

2019

Biologics for the treatment of chronic rhinosinusitis with nasal polyps : state of the art

Lei RenNan ZhangLuo ZhangClaus Bachert

A1 Journal Article in WORLD ALLERGY ORGANIZATION JOURNAL

Biologika in der Behandlung der chronischen Rhinosinusitis mit Nasenpolypen : Aktueller Stand

Nan ZhangClaus Bachert

A1 Journal Article in ALLERGOLOGIE

Comparison of a new Skin Prick Test Tape with the conventional skin prick test

Zhengpeng GongZhijie YangRan WuHuiping YeMin JiaNan ZhangClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Cross-talk between TH2 and TH17 pathways in patients with chronic rhinosinusitis with nasal polyps

Min WangNan ZhangMing ZhengYing LiLingling MengYu RuanJinbo HanNa ZhaoXiangdong WangLuo ZhangClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Development and characterization of DNAzyme candidates demonstrating significant efficiency against human rhinoviruses

Daniel P PotaczekSebastian D UngerNan ZhangStyliani TakaSven MichelNesibe AkdağFeng LanMarkus HelferChristoph HudemannMarkus EickmannChrysanthi SkevakiSpyridon MegremisAnne SadewasserBilal Alashkar AlhamweFahd AlhamdanMübeccel AkdisMichael R EdwardsSebastian L JohnstonCezmi A AkdisStephan BeckerClaus BachertNikolaos G PapadopoulosHolger GarnHarald Renz

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Development of antirhinoviral DNAzymes for effective prevention of asthma exacerbations

Daniel P PotaczekSebastian D UngerNan ZhangStyliani TakaSven MichelNesibe AkdagFeng LanMarkus HelferChristoph HudemannMarkus EickmannChrysanthi SkevakiSpyridon MegremisAnne SadewasserBilal Alashkar AlhamweFahd AlhamdanMubeccel AkdisMichael EdwardsSebastian L JohnstonCezmi A AkdisStephan BeckerClaus BachertNikolaos G PapadopoulosHolger GarnHarald E Renz

IFN-λ1 enhances Staphylococcus aureus clearance in healthy nasal mucosa but not in nasal polyps

Feng LanHua ZhongNan ZhangSebastian L JohnstonWeiping WenNikos PapadopoulosLuo ZhangClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Medical algorithm : diagnosis and treatment of chronic rhinosinusitis

Claus BachertNan Zhang

Editorial material

Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in IL-5-positive chronic rhinosinusitis with nasal polyps

Y ZhangLara DeryckeGabriële HoltappelsXD WangL ZhangClaus BachertNan Zhang

A1 Journal Article in ALLERGY

The effect of fine particulate matter on the inflammatory responses in human upper airway mucosa

Hui QingXiangdong WangNan ZhangKaili ZhengKun DuMing ZhengYing LiYu ChangLuo ZhangClaus Bachert

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

2018

Contribution of repeated infections in asthma persistence from preschool to school age : design and characteristics of the PreDicta cohort

Paraskevi XepapadakiClaus BachertSusetta FinottoTuomas JarttiGeorge N KonstantinouAlexander KieferMarek KowalskiAnna Lewandowska-PolakHeikki LukkarinenEirini RoumpedakiAnna SobanskaIna SintobinTytti VuorinenNan ZhangTheodor ZimmermannNikolaos G Papadopoulos

A1 Journal Article in PEDIATRIC ALLERGY AND IMMUNOLOGY

Development and characterization of effective DNAzymes against human rhinoviruses

DP PotaczekSD UngerNan ZhangS TakaS MichelN AkdagFeng LanM HelferC HudemannM EickmannC SkevakiS MegremisA SadewasserB Alashar AlhamweF AlhamdanCA AkdisS BeckerClaus BachertNG PapadopoulosH GarnH Renz

Endotype-driven care pathways in patients with chronic rhinosinusitis

Claus BachertNan ZhangPeter W HellingsJean Bousquet

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Highlights of eosinophilic chronic rhinosinusitis with nasal polyps in definition, prognosis, and advancement

Hongfei LouNan ZhangClaus BachertLuo Zhang

A1 Journal Article in INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY

Immunomodulatory effect of Bifidobacterium breve on experimental allergic rhinitis in BALB/c mice

Jianjun RenYu ZhaoShi HuangDan LvFengling YangLin LouYongbo ZhengJie ZhangShixi LiuNan ZhangClaus Bachert

A1 Journal Article in EXPERIMENTAL AND THERAPEUTIC MEDICINE

Multivariate analysis of inflammatory endotypes in recurrent nasal polyposis in a Chinese population

Bo WeiFeng LiuJie ZhangYafeng LiuJintao DuShixi LiuNan ZhangClaus BachertJuan Meng

A1 Journal Article in RHINOLOGY

Rhinovirus species-specific antibodies differentially reflect clinical outcomes in health and asthma

Spyridon MegremisKatarzyna NiespodzianaClarissa CabauatanParaskevi XepapadakiMarek L KowalskiTuomas JarttiClaus BachertSusetta FinottoPeter WestSofia StamatakiAnna Lewandowska-PolakHeikki LukkarinenNan ZhangTheodor ZimmermannFrank StolzAngela NeubauerMübeccel AkdisEvangelos AndreakosRudolf ValentaNikolaos G Papadopoulos

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Staphylococcus aureus controls interleukin-5 release in upper airway inflammation

Claus BachertGabriële HoltappelsMaia MerabishviliT MeyerA MurrNan ZhangKoen Van CrombruggenElien GevaertU VölkerBM BrökerMario VaneechoutteF Schmidt

A1 Journal Article in JOURNAL OF PROTEOMICS

Staphylococcus aureus enhances the tight junction barrier integrity in healthy nasal tissue, but not in nasal polyps

Can AltunbulakliRita CostaFeng LanNan ZhangMubeccel AkdisClaus BachertCezmi A Akdis

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Staphylococcus aureus induces a mucosal type 2 immune response via epithelial cell-derived cytokines

Feng LanNan ZhangGabriële HoltappelsNatalie De RuyckOlga KryskoKoen Van CrombruggenHarald BraunSebastian L JohnstonNikos G PapadopoulosLuo ZhangClaus Bachert

A1 Journal Article in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Th17 response against mucosal infection in persistent upper airways is partially impaired in viruses and bacteria coinfection condition

F LanL ZhangNan ZhangClaus Bachert

2017

Characterization of human and Staphylococcus aureus proteins in respiratory mucosa by in vivo- and immunoproteomics

Frank SchmidtTanja MeyerNandakumar SundaramoorthyStephan MichalikKristin SurmannMaren DepkeVishnu DhopleManuela Gesell SalazarGabriële HoltappelsNan ZhangBarbara M BrökerClaus BachertUwe Völker

A1 Journal Article in JOURNAL OF PROTEOMICS

Chronic rhinosinusitis in Asia

Yuan ZhangElien GevaertHongfei LouXiangdong WangLuo ZhangClaus BachertNan Zhang

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Extracellular eosinophilic traps in association with Staphylococcus aureus at the site of epithelial barrier defects in patients with severe airway inflammation

Elien GevaertNan ZhangOlga KryskoFeng LanGabriële HoltappelsNatalie De RuyckHans NauwynckShida YousefiHans-Uwe SimonClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Nasal polyposis and asthma : a mechanistic paradigm focusing on Staphylococcus aureus

Claus BachertNan ZhangOlga KryskoKoen Van CrombruggenElien Gevaert

Bookchapter in The nose and sinuses in respiratory disorders

Non-allergic rhinitis : position paper of the European Academy of Allergy and Clinical Immunology

PW HellingsL KlimekC CingiI AgacheC AkdisClaus BachertJ BousquetP DemolyPhilippe GevaertV HoxC HupinL KalogjeraF ManoleR MösgesJ MullolNB MulukA MuraroN PapadopoulosR PawankarC RondonM RundenkoSF SeysE ToskalaL Van GervenL ZhangNan ZhangWJ Fokkens

A1 Journal Article in ALLERGY

Programmed cell death-1 expression correlates with disease severity and IL-5 in chronic rhinosinusitis with nasal polyps

I Kortekaas KrohnS BobicJ DooleyFeng LanNan ZhangClaus BachertB SteelantDM BullensA ListonJL CeuppensSF SeysPW Hellings

A1 Journal Article in ALLERGY

2016

An increased prevalence of self-reported allergic rhinitis in major Chinese cities from 2005 to 2011

XD WangM ZhengHF LouCS WangY ZhangMY BoSQ GeNan ZhangL ZhangClaus Bachert

A1 Journal Article in ALLERGY

Barrier function of the nasal mucosa in health and type-2 biased airway diseases

Nan ZhangKoen Van CrombruggenElien GevaertClaus Bachert

A1 Journal Article in ALLERGY

Cellular phenotyping of chronic rhinosinusitis with nasal polyps

Hongfei LouYifan MengYingshi PiaoNan ZhangClaus BachertChengshuo WangLuo Zhang

A1 Journal Article in RHINOLOGY

Diversity of TH cytokine profiles in patients with chronic rhinosinusitis : a multicenter study in Europe, Asia, and Oceania

Xiangdong WangNan ZhangMingyu BoGabriële HoltappelsMing ZhengHongfei LouHong WangLuo ZhangClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Th2 biased upper airway inflammation is associated with an impaired response to viral infection with Herpes simplex virus 1

Feng LanXiang Dong WaneHans NauwynckGabriële HoltappelsLuo ZhangSebastian L JohnstonNikolaos G PapadopoulosClaus BachertNan Zhang

A1 Journal Article in RHINOLOGY

The role of viruses and Staphylococcus aureus in propagating a Th2 response in human nasal polyps

Feng LanClaus BachertNan Zhang

Viruses and bacteria in Th2-biased allergic airway disease

F LanNan ZhangElien GevaertL ZhangClaus Bachert

A1 Journal Article in ALLERGY

2015

Allergen-induced asthmatic responses modified by a GATA3-specific DNAzyme

Norbert KrugJens M HohlfeldAnne-Marie KirstenOliver KornmannKai M BeehDominik KappelerStephanie KornStanislav IgnatenkoWolfgang TimmerCordelia RogonJana ZeitvogelNan ZhangJoachim BilleUrsula HomburgAgnieszka TurowskaClaus BachertThomas WerfelRoland BuhlJonas RenzHolger GarnHarald Renz

A1 Journal Article in NEW ENGLAND JOURNAL OF MEDICINE

Association of mucosal organisms with patterns of inflammation in chronic rhinosinusitis

Thanit ChalermwatanachaiNan ZhangGabriële HoltappelsClaus Bachert

A1 Journal Article in PLOS ONE

Association of periostin expression with eosinophilic inflammation in nasal polyps

Min WangXiangdong WangNan ZhangHong WangYing LiErzhong FanLiang ZhangLuo ZhangClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Differential expression and release of activin A and follistatin in chronic rhinosinusitis with and without nasal polyps

Yucheng YangNan ZhangKoen Van CrombruggenFeng LanGuohua HuSuling HongClaus Bachert

A1 Journal Article in PLOS ONE

Effects of Bifidobacterium breve feeding strategy and delivery modes on experimental allergic rhinitis mice

Jian-Jun RenZhao YuFeng-Ling YangDan LvShi HungJie ZhangPing LinShi-Xi LiuNan ZhangClaus Bachert

A1 Journal Article in PLOS ONE

Staphyloccoccus aureus induces a Th2 response via TSLP and IL-33 release in human airway mucosa

Feng LanNan ZhangGabriële HoltappelsNatalie De RuyckNikolaos G PapadopoulosSebastian L JohnstonClaus Bachert

Staphylococcus aureus enterotoxin B induces airway epithelial barrier dysfunction in vitro

B SteelantFeng LanNan ZhangS SeysI Kortekaas KrohnJL CeuppensClaus BachertC AkdisPW Hellings

Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in chronic rhinosinusitis with nasal polyps

Yu ZhangLara DeryckeLuo ZhangGabriële HoltappelsXiangdong WangNan ZhangClaus Bachert

The clinical significance of the pollen calendar of the Western Thrace/northeast Greece region in allergic rhinitis

Michael KatotomichelakisChristos NikolaidisMichael MakrisNan ZhangXenophon AggelidesTheodoros C ConstantinidisClaus BachertVassilios Danielides

A1 Journal Article in INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY

2014

Different regulation of activin A and follistatin in chronic rhinosinusitis with or without nasal polyps

Y YangNan ZhangF LanKoen Van CrombruggenG HuS HongClaus Bachert

Staphyloccoccus aureus elicit epithelial cell-derived cytokine productions in human nasal tissue

F LanNan ZhangDX WangOlga KryskoGabriële HoltappelsNG PapadopoulosSL JohnstonClaus Bachert

Suppression of cytokine release by fluticasone furoate vs. mometasone furoate in human nasal tissue ex-vivo

Nan ZhangKoen Van CrombruggenGabriële HoltappelsFeng LanMichail KatotomichelakisLuo ZhangPetra HöggerClaus Bachert

A1 Journal Article in PLOS ONE

The effects of smoking on quality of life recovery after surgery for chronic rhinosinusitis

Michael KatotomichelakisEfthimios SimopoulosGregory TripsianisNan ZhangGerasimos DanielidesPanagiota GoumaClaus BachertVassilios Danielides

A1 Journal Article in RHINOLOGY

Transforming growth factor-beta 1 pathways in inflammatory airway diseases

Y YangNan ZhangF LanKoen Van CrombruggenL FangG HuS HongClaus Bachert

A1 Journal Article in ALLERGY

2013

Allergic fungal rhinosinusitis: more than a fungal disease?

TINEKE DUTRESurayie Al DousaryNan ZhangClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Damage‑associated molecular patterns and their receptors in upper airway pathologies

Koen Van CrombruggenFenila JacobNan ZhangClaus Bachert

A1 Journal Article in CELLULAR AND MOLECULAR LIFE SCIENCES

Forkhead box P3 in human airway regulatory T cells is regulated by suppressor of cytokine signaling

F LanNan ZhangJ ZhangOlga KryskoQ ZhangJ XianLara DeryckeY QiK LiS LiuP LinClaus Bachert

Forkhead box protein 3 in human nasal polyp regulatory T cells is regulated by the protein suppressor of cytokine signaling 3

Feng LanNan ZhangJie ZhangOlga KryskoQuanbo ZhangJunming XianLara DeryckeYanyu QiKai LiShixi LiuPing LinClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Olfactory dysfunction and asthma as risk factors for poor quality of life in upper airway diseases

Michael KatotomichelakisEfthimios SimopoulosNan ZhangGregory TripsianisGerasimos DanielidesMiltos LivaditisClaus BachertVassilios Danielides

A1 Journal Article in AMERICAN JOURNAL OF RHINOLOGY & ALLERGY

The development of nasal polyp disease involves early nasal mucosal inflammation and remodelling

Juan MengPeng ZhouYafeng LiuXuelian YiShixi LiuGabriële HoltappelsClaus BachertNan Zhang

A1 Journal Article in PLOS ONE

The pathogenesis of CRS : an update

Claus BachertNada Al BahraniSurayie Al DousaryKoen Van CrombruggenOlga KryskoClaudina Perez NovoNan Zhang

A2 Journal Article in CURRENT OTORHINOLARYNGOLOGY REPORTS

Uncontrolled allergic rhinitis and chronic rhinosinusitis: where do we stand today?

pW HellingsWJ FokkensC AkdisClaus BachertC CingiD Dietz de LoosPhilippe GevaertV HoxL KalogjeraV LundJ MullolNG PapadopoulosG PassalacquaC RondónG ScaddingM TimmermansE ToskalaNan ZhangJ Bousquet

A1 Journal Article in ALLERGY

2012

A herbal composition of Scutellaria baicalensis and Eleutherococcus senticosus shows potent anti-inflammatory effects in an ex vivo human mucosal tissue model

Nan ZhangKoen Van CrombruggenGabriële HoltappelsClaus Bachert

A1 Journal Article in EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE

Chronic rhinosinusitis and asthma: novel understanding of the role of IgE 'above atopy'

Claus BachertNan Zhang

A1 Journal Article in JOURNAL OF INTERNAL MEDICINE

Chronic rhinosinusitis: from one disease to different phenotypes

Claus BachertNan ZhangThibaut Van ZelePhilippe Gevaert

A1 Journal Article in PEDIATRIC ALLERGY AND IMMUNOLOGY

Herpes simplex virus type 1 infection facilitates invasion of Staphylococcus aureus into the nasal mucosa and nasal polyp tissue

XiangDong WangNan ZhangSarah GlorieuxGabriële HoltappelsMario VaneechoutteOlga KryskoLuo ZhangDeMin HanHans NauwynckClaus Bachert

A1 Journal Article in PLOS ONE

IL-17A as a regulator of neutrophil survival in nasal polyp disease of patients with and without cystic fibrosis

Lara DeryckeNan ZhangGabriële HoltappelsTINEKE DUTREClaus Bachert

A1 Journal Article in JOURNAL OF CYSTIC FIBROSIS

Specific IgE against Staphylococcus aureus enterotoxins: an independent risk factor for asthma

Claus BachertKristel Van SteenNan ZhangGabriële HoltappelsTom CattaertBärbel MausRoland BuhlChristian TaubeStephanie KornMarek KowalskiJean BousquetPeter Howarth

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Transforming growth factor-beta1 in inflammatory airway disease: a key for understanding inflammation and remodeling

YC YangNan ZhangKoen Van CrombruggenGH HuSL HongClaus Bachert

A1 Journal Article in ALLERGY

2011

Alternatively activated macrophages and impaired phagocytosis of S-aureus in chronic rhinosinusitis

Olga KryskoGabriële HoltappelsNan ZhangMalgorzata KubicaKim DeswarteLara DeryckeSofie ClaeysHamida HammadGuy BrussellePeter VandenabeeleDmitri KryskoClaus Bachert

A1 Journal Article in ALLERGY

Assessment of sleep impairment in persistent allergic rhinitis patients using polysomnography

J MengJ XuanX QiaoX LiS LiuKF LukatNan ZhangClaus Bachert

A1 Journal Article in INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Increased nasal IL-5 levels act as a predisposing factor of asthma in southern China reply

Claus BachertNan ZhangGabriële HoltappelsPETER TOMASSENShixi LiuPing LinJean Bousquet

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mucosal tissue polyclonal IgE is functional in response to allergen and SEB

Nan ZhangGabriële HoltappelsPhilippe GevaertJoke PatouB DhaliwalHannah GouldClaus Bachert

A1 Journal Article in ALLERGY

Pathogenesis of chronic rhinosinusitis: inflammation

Koen Van CrombruggenNan ZhangPhilippe GevaertPETER TOMASSENClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Pathophysiology of chronic rhinosinusitis

PETER TOMASSENThibaut Van ZeleNan ZhangClaudina Perez NovoNICHOLAS VAN BRUAENEPhilippe GevaertClaus Bachert

A2 Journal Article in PROCEEDINGS OF THE AMERICAN THORACIC SOCIETY

The association between bacterial colonization and inflammatory pattern in Chinese chronic rhinosinusitis patients with nasal polyps

L BaNan ZhangJ MengJ ZhangP LinP ZhouS LiuClaus Bachert

A1 Journal Article in ALLERGY

2010

CRTH2 mediates the activation of human Th2 cells in response to PGD2 released from IgE/anti-IgE treated nasal polyp tissue

Claudina Perez NovoGabriële HoltappelsShân L VinallLuzheng XueNan ZhangClaus BachertRoy Pettipher

A1 Journal Article in ALLERGY

Expression of TGF, matrix metalloproteinases, and tissue inhibitors in Chinese chronic rhinosinusitis

Xiaoyuan LiJuan MengXiaoming QiaoYafeng LuiFeng LiuNan ZhangJie ZhangGabriële HoltappelsBa LuoPeng ZhuoYongbo ZhengPing LinShixi LiuClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Inflammatory profiles in nasal mucosa of patients with persistent vs intermittent allergic rhinitis

F LiuJ ZhangY LiuNan ZhangGabriële HoltappelsP LinS LiuClaus Bachert

A1 Journal Article in ALLERGY

Presence of IL-5 protein and IgE antibodies to staphylococcal enterotoxins in nasal polyps is associated with comorbid asthma

Claus BachertNan ZhangGabriële HoltappelsLizzy De LobelPaul Van CauwenbergeShiXi LiuPing LinJean BousquetKristel Van Steen

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Remodeling and inflammation in Chinese versus white patients with chronic rhinosinusitis

Nan ZhangShixi LiuPing LinXiaoyuan LiNICHOLAS VAN BRUAENEJie ZhangThibaut Van ZeleClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Rhinosinusitis and asthma : a link for asthma severity

Claus BachertSofie ClaeysPeter TomassenThibaut Van ZeleNan Zhang

A1 Journal Article in CURRENT ALLERGY AND ASTHMA REPORTS

Staphylococcus aureus-derived superantigens in nasal polyp disease

Peter TomassenThibaut Van ZelePhilippe GevaertNan ZhangClaudina Perez NovoNICHOLAS VAN BRUAENEJoke PatouClaus Bachert

Bookchapter in Nasal polyposis : pathogenesis, medical and surgical treatment

2009

Chronic rhinosinusitis with and without nasal polyps: what is the difference?

Wouter HuvenneNICHOLAS VAN BRUAENENan ZhangThibaut Van ZeleJoke PatouPhilippe GevaertSofie ClaeysPaul Van CauwenbergeClaus Bachert

A1 Journal Article in Current Allergy and Asthma Reports

Detection of Staphylococcus aureus in nasal tissue with peptide nucleic acid-fluorescence in situ hybridization

Marie-Noelle CorriveauNan ZhangGabriële HoltappelsNadine Van RoyClaus Bachert

A1 Journal Article in AMERICAN JOURNAL OF RHINOLOGY & ALLERGY

Important research questions in allergy and related diseases: 3-chronic rhinosinusitis and nasal polyposis - a GA(2)LEN study

Claus BachertNICHOLAS VAN BRUAENEE ToskalaNan ZhangH OlzeG ScaddingCM Van DrunenJ MullolL CardellPhilippe GevaertThibaut Van ZeleSofie ClaeysC HalldenK KostamoU FoersterM KowalskiK BieniekA Olszewska-ZiaberE Nizankowska-MogilnickaA SzczeklikM SwierczynskaM ArcimowiczV LundW FokkensT ZuberbierC AkdisG CanonicaPaul Van CauwenbergeP BurneyJ Bousquet

A1 Journal Article in ALLERGY

The presence of Staphylococcus aureus is not equivalent to an immune reaction to it's enterotoxins

MN CorriveauNan ZhangClaus Bachert

A1 Journal Article in ALLERGY

2008

Different types of T-effector cells orchestrate mucosal inflammation in chronic sinus disease

Nan ZhangThibaut Van ZeleClaudina Perez NovoNICHOLAS VAN BRUAENEGabriële HoltappelsNatalie De RuyckPaul Van CauwenbergeClaus Bachert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Pilot study using doxycycline-releasing stents to ameliorate postoperative healing quality after sinus surgery

WOUTER HUVENNENan ZhangE TijsmaB HissongJ HuurdemanG HoltappelsSofie ClaeysPaul Van CauwenbergeHans NelisTom CoenyeClaus Bachert

A1 Journal Article in Wound Repair and Regeneration

Role of staphylococcal superantigens in upper airway disease

Claus BachertNan ZhangJoke PatouThibaut Van ZelePhilippe Gevaert

A1 Journal Article in CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY

2007

Remodelling in nasal polyposis is independent of TH-cell polarisation

Nan ZhangTV ZELEPhilippe GevaertGabriële HoltappelsP VAN CAUWENBERGEClaus Bachert

Role of Staphylococcal superantigens in airway disease

Claus BachertPhilippe GevaertNan ZhangThibaut Van ZeleClaudina Perez Novo

Bookchapter in Superantigens and superallergens

Role of staphylococcal superantigens in airway disease: a review, part 2: S-aureus enterotoxins in AERD, asthma, early childhood wheezing and COPD

Claus BachertNan ZhangPhilippe GevaertThibaut Van ZeleClaudina Perez Novo

A1 Journal Article in ALLERGOLOGIE

Staphylococcal superantigens in airway disease: a review, part 1: the role of S-aureus enterotoxins in allergic rhinitis and nasal polyps

Claus BachertPhilippe GevaertNan ZhangThibaut Van ZeleClaudina Perez Novo

A1 Journal Article in ALLERGOLOGIE

Staphylococcus Aureus Enterotoxins as Immune Stimulants in Chronic Rhinosinusitis

Claus BachertNan ZhangThibaut Van ZelePhilippe GevaertJoke PatouPaul Van Cauwenberge

Bookchapter in Chronic Rhinosinusitis

2006

Pattern of inflammation and impact of Staphylococcus aureus enterotoxins in nasal polyps from southern China

Nan ZhangGabriële HoltappelsCindy ClaeysGQ HUANGPaul Van CauwenbergeClaus Bachert

A1 Journal Article in AMERICAN JOURNAL OF RHINOLOGY

2005

An update on the impact of Staphylococcus aureus enterotoxins in chronic sinusitis with nasal polyposis

Nan ZhangPhilippe GevaertThibaut Van ZeleClaudina Perez NovoJoke PatouGabriële HoltappelsPaul Van CauwenbergeClaus Bachert

A1 Journal Article in RHINOLOGY