Research Explorer

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Researcher

Michel Struys

291 Results

2021

Frontal electroencephalogram based drug, sex, and age independent sedation level prediction using non-linear machine learning algorithms

S. M. RamaswamyM. H. KuizengaM. A. S. WeerinkH. E. M. VereeckeMichel StruysS. Belur Nagaraj

A1 Journal Article in JOURNAL OF CLINICAL MONITORING AND COMPUTING

Inhaled anesthetics : environmental role, occupational risk, and clinical use

Mariana Gaya da CostaAlain KalmarMichel Struys

A1 Journal Article in JOURNAL OF CLINICAL MEDICINE

Modeling the effect of excitation on depth of anesthesia monitoring in gamma-aminobutyric acid type A receptor agonist ABP-700

Beatrijs I. ValkDouglas J. EleveldPeter MeyerSascha MeierIzaak den DaasKai van AmsterdamJason A. CampagnaSteven P. SweeneyAnthony R. AbsalomMichel Struys

A1 Journal Article in ANESTHESIOLOGY

Modeling the effect of excitation on depth of anesthesia monitoring in gamma-aminobutyric acid type A receptor agonist ABP-700 (vol 134, pg 35, 2021)

I Valk, B.D. J. EleveldP. MeyerS. MeierI den DaasK. van AmsterdamJ. A. CampagnaS. P. SweeneyA. R. AbsalomMichel Struys

Perioperative SARS-CoV-2 infections increase mortality, pulmonary complications, and thromboembolic events : a Dutch, multicenter, matched-cohort clinical study

Pascal K. C. JonkerWillemijn Y. Van der PlasPieter J. SteinkampRalph PoelstraMarloes EmousWout Van der MeijFloris ThunnissenWouter F. W. BiermanMichel StruysPhilip R. de ReuverJean-Paul P. M. de VriesSchelto Kruijff

A1 Journal Article in SURGERY

Population pharmacodynamic modeling using the sigmoid E-max model : influence of inter-individual variability on the steepness of the concentration-effect relationship : a simulation study

Johannes H. ProostDouglas J. EleveldMichel Struys

A1 Journal Article in AAPS JOURNAL

Propofol-based anaesthesia versus sevoflurane-based anaesthesia for living donor kidney transplantation : results of the VAPOR-1 randomized controlled trial (vol 118, pg 720, 2017)

Gertrude J. Nieuwenhuijs-MoekeVincent B. NieuwenhuijsMarc A. J. SeelenStefan P. BergerMarius C. van den HeuvelJohannes G. M. BurgerhofPetra J. OttensRutger J. PloegHenri G. D. LeuveninkMichel Struys

Prospective clinical validation of the Eleveld propofol pharmacokinetic-pharmacodynamic model in general anaesthesia

R VellingaLN HannivoortM IntronaDJ TouwAR AbsalomDJ EleveldMichel Struys

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Resisting neural inertia : an exercise in floccinaucinihilipilification?

DJ EleveldPJ ColinAR AbsalomMichel Struys

Editorial material

Study of Bayesian-based closed-loop drug administration for propofol in anesthesia and sedation

Martine NeckebroekMichel StruysClara-Mihaela Ionescu

2020

Autonomous systems in anesthesia : where do we stand in 2020? A narrative review

Cedrick ZaouterAlexandre JoostenJoseph RinehartMichel StruysThomas M. Hemmerling

A1 Journal Article in ANESTHESIA AND ANALGESIA

Comparison of haemodynamic- and electroencephalographic-monitored effects evoked by four combinations of effect-site concentrations of propofol and remifentanil, yielding a predicted tolerance to laryngoscopy of 90%

J. P. van den BergA. R. AbsalomA. M. VenemaAlain KalmarK. Van AmsterdamL. N. HannivoortJ. H. ProostS. MeierT. W. L. ScheerenMichel StruysH. E. M. Vereecke

A1 Journal Article in JOURNAL OF CLINICAL MONITORING AND COMPUTING

Driving pressure during general anesthesia for open abdominal surgery (DESIGNATION) : study protocol of a randomized clinical trial

Liselotte HolSunny G. L. H. NijbroekAry Serpa NetoMarcelo Gama de AbreuPaolo PelosiSabrine N. T. HemmesLeon P. H. J. AartsRonald D. L. AkkermanJuliette J. E. AlbersenCaterina AurilioDenise BattagliniHans D. de BoerAnnemieke BoomChrista BoerTammo BrouwerWolfgang F. F. A. BuhreCarolina S. E. BulteGitara M. Edward-RuttenMarc B. GodfriedHendrik J. F. HelmerhorstJan HoflandHester HoogenboomW. Ten HoopeBernard M. HouwelingRagnar HuhnWanda KonijnAnkie W. M. M. Koopman-van GemertDianne J. De Korte-de BoerMinke C. KortekaasFelix Van LierBenedikt PreckelMandana RadPasquale SansoneAndre StamkotRobert Jan StolkerBram ThielJohannes F. H. UbbenMichel StruysBastiaan A. In 't VeldHermann WriggeMiriam Zeillemaker-HoekstraTim van der ZwanJohannes H. M. J. ZwijsenMarkus W. HollmannMarcus J. Schultz

A1 Journal Article in TRIALS

Effects of propofol and dexmedetomidine with and without remifentanil on serum cytokine concentrations in healthy volunteers : a post hoc analysis

Dirk J. BoschV Meurs, MatijsRianne M. JongmanPeter HeeringaWayel H. AbdulahadMichel Struys

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Influence of an "electroencephalogram-based" monitor choice on the delay between the predicted propofol effect-site concentration and the measured drug effect

Marko M. SahinovicJohannes P. van den BergPieter J. ColinPedro L. GambusErik W. JensenMerce AgustiTeresa FerreiroMichel Struys

A1 Journal Article in ANESTHESIA AND ANALGESIA

Influence of remifentanil on the control performance of the bispectral index controlled Bayesian-based closed-loop system for propofol administration

Martine NeckebroekJan-Willem H. L. BoldinghTom De SmetMichel Struys

A1 Journal Article in ANESTHESIA AND ANALGESIA

Intranasal dexmedetomidine in elderly subjects with or without beta blockade : a randomised double-blind single-ascending-dose cohort study.

Clemens R M BarendsMendy K DriesensMichel StruysAnita VisserAnthony R Absalom

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Ischemia and reperfusion injury in kidney transplantation : relevant mechanisms in injury and repair

Gertrude J. Nieuwenhuijs-MoekeSoren E. PischkeStefan P. BergerJan Stephan F. SandersRobert A. PolMichel StruysRutger J. PloegHenri G. D. Leuvenink

A1 Journal Article in JOURNAL OF CLINICAL MEDICINE

Meta-analysis of ketamine pharmacokinetics : lots of work done but still lots to do

Douglas J. EleveldMichel Struys

Editorial material

Moderate-to-deep sedation using target-controlled infusions of propofol and remifentanil : adverse events and risk factors : a retrospective cohort study of 2937 procedures

Clemens R. M. BarendsMendy K. DriesensKai van AmsterdamMichel StruysAnthony R. Absalom

A1 Journal Article in ANESTHESIA AND ANALGESIA

Predicting deep hypnotic state from sleep brain rhythms using deep learning : a data-repurposing approach

Sunil Belur NagarajSowmya M. RamaswamyMaud A. S. WeerinkMichel Struys

A1 Journal Article in ANESTHESIA AND ANALGESIA

Sevoflurane, a sigh of relief in COVID-19?

Gertrude J. Nieuwenhuijs-MoekeJayant S. JainandunsingMichel Struys

Editorial material

Target-controlled infusion of cefepime in critically Ill patients

Stijn JonckheereNikolaas De NeveJan VerbekeKoen De DeckerInger BrandtAn BoelJan Van BocxlaerMichel StruysPieter J. Colin

A1 Journal Article in ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Target-controlled-infusion models for remifentanil dosing consistent with approved recommendations

Douglas J. EleveldPieter ColinAnthony R. AbsalomMichel Struys

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Ten years of the Helsinki Declaration on patient safety in anaesthesiology : an expert opinion on peri-operative safety aspects

Benedikt PreckelSven StaenderDaniel ArnalGuttorm BratteboJeffrey M. FeldmanRobert Ffrench-O'CarrollThomas Fuchs-BuderSara N. Goldhaber-FiebertGuy HallerArvid S. HaugenJan F. A. HendrickxCor J. KalkmanPatrick MeybohmChristopher NeuhausDoris OstergaardAdrian PlunkettHans U. SchulerAndrew F. SmithMichel StruysChristian P. SubbeJohannes WackerJohn WelchDavid K. WhitakerKai ZacharowskiJannicke Mellin-Olsen

A1 Journal Article in EUROPEAN JOURNAL OF ANAESTHESIOLOGY

The role of pharmacokinetics and pharmacodynamics in clinical anaesthesia practice

Laura N. HannivoortAnthony R. AbsalomMichel Struys

A1 Journal Article in CURRENT OPINION IN ANESTHESIOLOGY

2019

Collateral ventilation measurement using chartis procedural sedation vs general anesthesia

Jorrit WellingKarin KloosterJorine HartmanHuib KerstjensIna FranzMichel StruysAnthony AbsalomDirk-Jan SlebosClemens Barends

A1 Journal Article in CHEST

Corrigendum to ‘Do we need inhaled anaesthetics toblunt arousal, haemodynamic responses tointubation after i.v. induction with propofol,remifentanil, rocuronium?’ [Br J Anaesth 2006; 97:835-841]

Marc CoppensLinda VersichelenEric MortierMichel Struys

Intraoperative fluid restriction is associated with functional delayed graft function in living donor kidney transplantation : a retrospective cohort analysis

Gertrude J Nieuwenhuijs-MoekeTobias M HuijinkRobert A PolMostafa El MoumniJohannes GM BurgerhofMichel StruysStefan P Berger

A1 Journal Article in JOURNAL OF CLINICAL MEDICINE

Novel drug-independent sedation level estimation based on machine learning of quantitative frontal electroencephalogram features in healthy volunteers

Sowmya M RamaswamyMerel H KuizengaMaud AS WeerinkHugo EM VereeckeMichel StruysSunil B Nagaraj

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Opioids : refining the perioperative role of God's own medicine

DW HewsonMichel StruysJG Hardman

Editorial material

Oxygen reserve index : validation of a new variable

Jaap Jan VosCornelis H WillemsKai van AmsterdamJohannes P van den BergRob SpanjersbergMichel StruysThomas WL Scheeren

A1 Journal Article in ANESTHESIA AND ANALGESIA

Pharmacodynamic interaction of remifentanil and dexmedetomidine on depth of sedation and tolerance of laryngoscopy

Maud A. S. WeerinkClemens R. M. BarendsErnesto R. R. MuskietKoen M. E. M. ReyntjensFroukje H. KnotnerusMartine OostraJan Van BocxlaerMichel StruysPieter Colin

A1 Journal Article in ANESTHESIOLOGY

Population pharmacodynamics of propofol and sevoflurane in healthy volunteers using a clinical score and the patient state index : a crossover study

Merel H KuizengaPieter ColinKoen MEM ReyntjensDaan J TouwHasan NalbatFroukje H KnotnerusHugo EM VereeckeMichel Struys

A1 Journal Article in ANESTHESIOLOGY

Vancomycin pharmacokinetics throughout life : results from a pooled population analysis and evaluation of current dosing recommendations

Pieter ColinKarel AllegaertAlison H ThomsonDaan J TouwMichael DoltonMatthijs de HoogJason A RobertsEyob D AdaneMasato YamamotoDolores Santos-BuelgaAna Martin-SuarezNicolas SimonFabio S TacconeYoke-Lin LoEmilia BarciaMichel StruysDouglas J Eleveld

A1 Journal Article in CLINICAL PHARMACOKINETICS

2018

Brain changes due to hypoxia during light anaesthesia can be prevented by deepening anaesthesia : a study in rats

Setayesh R TasbihgouMina NetkovaAlain KalmarJanine DoorduinMichel StruysRegien G SchoemakerAnthony R Absalom

A1 Journal Article in PLOS ONE

Clinical pharmacokinetics and pharmacodynamics of propofol

Marko M SahinovicMichel StruysAnthony R Absalom

A1 Journal Article in CLINICAL PHARMACOKINETICS

Drug selection for ambulatory procedural sedation

Clemens RM BarendsAnthony R AbsalomMichel Struys

A1 Journal Article in CURRENT OPINION IN ANESTHESIOLOGY

European Society of Anaesthesiology and European Board of Anaesthesiology guidelines for procedural sedation and analgesia in adults

Jochen HinkelbeinMassimo LampertiJonas AkesonJoao SantosJoao CostaEdoardo De RobertisDan LongroisVesna Novak-JankovicFlavia PetriniMichel StruysFrancis VeyckemansThomas Fuchs-BuderRobert Fitzgerald

A1 Journal Article in EUROPEAN JOURNAL OF ANAESTHESIOLOGY

Pharmacokinetic pharmacodynamic perspective on the detection of signs of neural inertia in humans

Pieter ColinMerel H KuizengaHugo EM VereeckeMichel Struys

A1 Journal Article in ANESTHESIOLOGY

Pharmacokinetic-pharmacodynamic model for propofol for broad application in anaesthesia and sedation

DJ EleveldPieter ColinAR AbsalomMichel Struys

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Phenylephrine increases cardiac output by raising cardiac preload in patients with anesthesia induced hypotension

Alain KalmarS AllaertP PletinckxJ-W MaesJ HeermanJJ VosMichel StruysTWL Scheeren

A1 Journal Article in JOURNAL OF CLINICAL MONITORING AND COMPUTING

Preemptively and non-preemptively transplanted patients show a comparable hypercoagulable state prior to kidney transplantation compared to living kidney donors

Gertrude J Nieuwenhuijs-MoekeTamar AJ van den BergStephan JL BakkerMarius C van den HeuvelMichel StruysTon LismanRobert A Pol

A1 Journal Article in PLOS ONE

Safety and clinical effect of i.v. infusion of cyclopropyl-methoxycarbonyl etomidate (ABP-700), a soft analogue of etomidate, in healthy subjects

BI ValkAR AbsalomP MeyerS MeierI den DaasK van AmsterdamJA CampagnaSP SweeneyMichel Struys

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Target-controlled continuous infusion for antibiotic dosing : proof-of-principle in an in-silico vancomycin trial in intensive care unit patients

Pieter ColinStijn JonckheereMichel Struys

A1 Journal Article in CLINICAL PHARMACOKINETICS

Test of neural inertia in humans during general anaesthesia

MH KuizengaPieter ColinKMEM ReyntjensDJ TouwH NalbatFH KnotnerusHEM VereeckeMichel Struys

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

2017

A phase 1, single-center, double-blind, placebo-controlled study in healthy subjects to assess the safety, tolerability, clinical effects, and pharmacokinetics-pharmacodynamics of intravenous cyclopropyl-methoxycarbonylmetomidate (ABP-700) after a single ascending bolus dose

Michel StruysBeatrijs I ValkDouglas J EleveldAnthony R AbsalomPeter MeyerSascha MeierIzaak den DaasThomas ChouKai van AmsterdamJason A CampagnaSteven P Sweeney

A1 Journal Article in ANESTHESIOLOGY

An allometric model of remifentanil pharmacokinetics and pharmacodynamics

Douglas J EleveldJohannes H ProostHugo VereeckeAnthony R AbsalomErik OlofsenJaap VuykMichel Struys

A1 Journal Article in ANESTHESIOLOGY

Clinical pharmacokinetics and pharmacodynamics of dexmedetomidine

Maud AS WeerinkMichel StruysLaura N HannivoortClemens RM BarendsAnthony R AbsalomPieter Colin

A1 Journal Article in CLINICAL PHARMACOKINETICS

Dexmedetomidine pharmacodynamics in healthy volunteers, 2 : haemodynamic profile

Pieter ColinLN HannivoortDJ EleveldKMEM ReyntjensAR AbsalomHEM VereeckeMichel Struys

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Dexmedetomidine pharmacokineticpharmacodynamic modelling in healthy volunteers, 1 : influence of arousal on bispectral index and sedation

Pieter ColinLN HannivoortDJ EleveldKMEM ReyntjensAR AbsalomHEM VereeckeMichel Struys

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Influence of Bayesian optimization on the performance of propofol target-controlled infusion

JP van den BergDJ EleveldT De SmetAVM van den HeerikK van AmsterdamBJ LichtenbeltTWL ScheerenAR AbsalomMichel Struys

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Patient safety during procedural sedation using capnography monitoring : a systematic review and meta-analysis

Rhodri SaundersMichel StruysRichard F PollockMichael MestekJenifer R Lightdale

A1 Journal Article in BMJ OPEN

Pharmacokinetic and pharmacodynamic interactions in anaesthesia : a review of current knowledge and how it can be used to optimize anaesthetic drug administration

JP van den BergHEM VereeckeJH ProostDJ EleveldJKG WietaschAR AbsalomMichel Struys

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Pharmacokinetics and pharmacodynamics of propofol : changes in patients with frontal brain tumours

MM SahinovicDJ EleveldT Miyabe-NishiwakiMichel StruysAR Absalom

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Predictive performance of eleven pharmacokinetic models for propofol infusion in children for long-duration anaesthesia

M HaraK MasuiDJ EleveldMichel StruysO Uchida

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Prophylactic atropine administration attenuates the negative haemodynamic effects of induction of anaesthesia with propofol and high-dose remifentanil : a randomised controlled trial

Marieke PotermanThomas WL ScheerenMarieke I van der VeldePieter L BuismanSilvie AllaertMichel StruysAlain Kalmar

A1 Journal Article in EUROPEAN JOURNAL OF ANAESTHESIOLOGY

Propofol-based anaesthesia versus sevoflurane-based anaesthesia for living donor kidney transplantation : results of the VAPOR-1 randomized controlled trial

GJ Nieuwenhuijs-MoekeVB NieuwenhuijsMAJ SeelenSP BergerM van den HeuvelJGM BurgerhofPJ OttensRJ PloegHGD LeuveninkMichel Struys

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

The pharmacodynamics of hypnotic and analgesic drug combinations as measured by clinical and electroencephalographic effects

Bjorn HeyseLuc De BaerdemaekerMichel Struys

Tracking electroencephalographic changes using distributions of linear models : application to propofol-vased depth of anesthesia monitoring

Levin KuhlmannJonathan H MantonBjorn HeyseHugo EM VereeckeTarmo LippingMichel StruysDavid TJ Liley

A1 Journal Article in IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

2016

Comparisons of electroencephalographically derived measures of hypnosis and antinociception in response to standardized stimuli during target-controlled propofol-remifentanil anesthesia

Mehrnaz ShoushtarianMarko M SahinovicAnthony R AbsalomAlain KalmarHugo EM VereeckeDavid TJ LileyMichel Struys

A1 Journal Article in ANESTHESIA AND ANALGESIA

Innovative local pressure measurement techniques for diagnostic and therapeutic optimisation in organ systems

Alain KalmarPascal VerdonckKoenraad MonsieursMichel Struys

Model-based drug administration: current status of target-controlled infusion and closed-loop control

Merel H KuizengaHugo EM VereeckeMichel Struys

A1 Journal Article in CURRENT OPINION IN ANESTHESIOLOGY

Neural mass model-based tracking of anesthetic brain states

Levin KuhlmannDean R FreestoneJonathan H MantonBjorn HeyseHugo EM VereeckeTarmo LippingMichel StruysDavid TJ Liley

A1 Journal Article in NEUROIMAGE

Performance of the Eleveld pharmacokinetic model to titrate propofol in an obese Japanese patient population

Hugo EM VereeckeDouglas J EleveldPieter ColinMichel Struys

A1 Journal Article in EUROPEAN JOURNAL OF ANAESTHESIOLOGY

Probability to tolerate laryngoscopy and noxious stimulation response index as general indicators of the anaesthetic potency of sevoflurane, propofol, and remifentanil

LN HannivoortHEM VereeckeJH ProostBjorn HeyseDJ EleveldTW BouillonMichel StruysM Luginbühl

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Propofol breath monitoring as a potential tool to improve the prediction of intraoperative plasma concentrations

Pieter ColinDouglas J EleveldJohannes P van den BergHugo EM VereeckeMichel StruysGustav SchellingChrisitan C ApfelCyrill Hornuss

A1 Journal Article in CLINICAL PHARMACOKINETICS

Target-controlled infusion: a mature technology

Anthony R AbsalomJohn (Iain) B GlenGerrit JC ZwartThomas W SchniderMichel Struys

A1 Journal Article in ANESTHESIA AND ANALGESIA

The history of target-controlled infusion

Michel StruysTom De SmetJohn (Iain) B GlenHugo EM VereeckeAnthony R AbsalomThomas W Schnider

A1 Journal Article in ANESTHESIA AND ANALGESIA

The safety of target-controlled infusions

Thomas W SchniderCharles F MintoMichel StruysAnthony R Absalom

A1 Journal Article in ANESTHESIA AND ANALGESIA

2015

A new pharmacokinetic model of propofol: effect of age on clearance and impact of the terminal distribution phase: response

Douglas J EleveldJohannes H ProostAnthony R AbsalomLuis I CortinezMichel Struys

A1 Journal Article in ANESTHESIA AND ANALGESIA

Comparisons of electroencephalographically derived measures of hypnosis and antinociception during propofol-remifentanil anesthesia

M ShoushtarianMarco M SahinovicAnthony R AbsalomAlain KalmarHUGO VEREECKEDTJ LileyMichel Struys

Development and implementation of feed-back controlled drug administration during anesthesia and sedation

Tom De SmetMichel StruysEric Mortier

Differential effects of phenylephrine and norepinephrine on peripheral tissue oxygenation during general anaesthesia: a randomised controlled trial

Marieke PotermanJaap Jan VosHugo EM VereeckeMichel StruysHenk VanoverscheldeThomas WL ScheerenAlain Kalmar

A1 Journal Article in EUROPEAN JOURNAL OF ANAESTHESIOLOGY

Noninvasive pulse pressure variation and stroke volume variation to predict fluid responsiveness at multiple thresholds : a prospective observational study

Jaap Jan VosMarieke PotermanPieternel Papineau SalmKai Van AmsterdamMichel StruysThomas WL ScheerenAlain Kalmar

A1 Journal Article in CANADIAN JOURNAL OF ANESTHESIA-JOURNAL CANADIEN D ANESTHESIE

Nonlinear dynamics of the patient's response to drug effect during general anesthesia

Clara-Mihaela IonescuJose Tenreiro MachadoRobain De KeyserJohan DecruyenaereMichel Struys

A1 Journal Article in COMMUNICATIONS IN NONLINEAR SCIENCE AND NUMERICAL SIMULATION

2014

A general purpose pharmacokinetic model for propofol

Douglas J EleveldJohannes H ProostLuis I CortinezAnthony R AbsalomMichel Struys

A1 Journal Article in ANESTHESIA AND ANALGESIA

A response surface model approach for continuous measures of hypnotic and analgesic effect during sevoflurane-remifentanil interaction: quantifying the pharmacodynamic shift evoked by stimulation

Bjorn HeyseJohannes H ProostLaura N HannivoortDouglas J EleveldMartin LuginbühlMichel StruysHUGO VEREECKE

A1 Journal Article in ANESTHESIOLOGY

Accuracy of the composite variability index as a measure of the balance between nociception and, antinociception during anesthesia

Marco M SahinovicDouglas J EleveldAlain KalmarEleonora H HeeremansTom De SmetChandran V SeshagiriAnthony R AbsalomHUGO VEREECKEMichel Struys

A1 Journal Article in ANESTHESIA AND ANALGESIA

Bispectral index values and propofol concentrations at loss and return of consciousness in patients with frontal brain tumours and control patients

MM SahinovicU BeeseEH HeeremansAlain KalmarK van AmsterdamRJHM SteenbakkersH KuiperR SpanjersbergRJM GroenMichel StruysAR Absalom

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Comparison of continuous non-invasive finger arterial pressure monitoring with conventional intermittent automated arm arterial pressure measurement in patients under general anaesthesia

JJ VosM PotermanEAQ MooyaartM WeeningMichel StruysTWL ScheerenAlain Kalmar

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Hemodynamics and tissue oxygenation during balanced anesthesia with a high antinociceptive contribution : an observational study

Jaap Jan VosMarieke PotermanLaura N HannivoortVictor W Renardel De LavaletteMichel StruysThomas WL ScheerenAlain Kalmar

A2 Journal Article in PERIOPERATIVE MEDICINE

Moxifloxacin dosing in post-bariatric surgery patients

Pieter ColinDouglas J EleveldMichel StruysHuybrecht T'jollynLucas Van BortelJohannes RuigeJan De WaeleJan Van BocxlaerKoen Boussery

A1 Journal Article in BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

2013

Automated drug delivery in anesthesia

Martine NeckebroekTom De SmetMichel Struys

A2 Journal Article in CURRENT ANESTHESIOLOGY REPORTS

Bilateral BIS compatible with loss of response to name calling: comparison between patients with and without a brain tumour

Barbara WylerStefan De HertA AbsalomMichel StruysHUGO VEREECKE

Comparison of arterial pressure and plethysmographic waveform-based dynamic preload variables in assessing fluid responsiveness and dynamic arterial tone in patients undergoing major hepatic resection

JJ VosAlain KalmarMichel StruysJKG WietaschHGD HendriksTWL Scheeren

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Influence of the method of PK and PD modeling on the objective function and the PD parameters

Laura N HannivoortBarbara WylerDouglas J EleveldAnthony R AbsalomHUGO VEREECKEMichel Struys

Interaction between nitrous oxide, sevoflurane, and opioids: a response surface approach

HUGO VEREECKEJohannes H ProostBjorn HeyseDouglas J EleveldTakasumi KatohMartin LuginbühlMichel Struys

A1 Journal Article in ANESTHESIOLOGY

Study of the application of pharmacokinetic-pharmacodynamic modeling to optimize propofol administration during anaesthesia

Marc CoppensMichel StruysPeter De Paepe

The response of bispectral index to laryngoscopy, comparison between hemispheres in patients with a brain tumour versus a healthy control group

Stefan De HertPIET WYFFELSMichel StruysHUGO VEREECKEBarbara WylerJean-Pierre Kalala Okito

2012

Accuracy of non-invasive measurement of haemoglobin concentration by pulse co-oximetry during steady-state and dynamic conditions in liver surgery

JJ VosAlain KalmarMichel StruysRJ PorteJKG WietaschTWL ScheerenHGD Hendriks

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Bispectral index at loss of consciousness and in response to laryngposcopy measured on healthy hemispheres during pseudo-steady state propofol and remifentanil anesthesia

JELLE HOUTHOOFDBarbara WylerJean-Pierre Kalala OkitoMichel StruysHUGO VEREECKE

Cerebral haemodynamic physiology during steep Trendelenburg position and CO2 pneumoperitoneum

Alain KalmarFrank DewaeleLuc FoubertJan F HendrickxEleanora HeeremansMichel Struys

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Reference values and clinical application of magnetic peripheral nerve stimulation in cats

Iris Van SoensMichel StruysSofie BhattiLuc Van Ham

A1 Journal Article in VETERINARY JOURNAL

Sevoflurane remifentanil interaction: comparison of different response surface models

Bjorn HeyseJohannes H ProostPeter M SchumacherTomas W BouillonHugo EM VereeckeDouglas J EleveldMartin LuginbuhlMichel Struys

A1 Journal Article in ANESTHESIOLOGY

The response of bispectral index to laryngoscopy, comparison between healthy hemispheres during pseudo-steady state propofol and remifentanil anesthesia

JELLE HOUTHOOFDBarbara WylerJean-Pierre Kalala OkitoMichel StruysHUGO VEREECKE

2011

An evaluation of using population pharmacokinetic models to estimate pharmacodynamic parameters for propofol and bispectral index in children

Marc CoppensDouglas J EleveldJohannes H ProostLuc MarksJan Van BocxlaerHugo VereeckeAnthony R AbsalomMichel Struys

A1 Journal Article in ANESTHESIOLOGY

Closed loop anesthesia: are we getting close to finding the Holy Grail?

Anthony R AbsalomRobain De KeyserMichel Struys

Editorial material

Evaluation of a propofol and remifentanil interaction model for predictive control of anesthesia induction

Clara-Mihaela IonescuRobain De KeyserMichel Struys

Hemodynamic physiology during perioperative intracranial hypertension : monitoring and therapeutic implications

Alain KalmarMichel StruysEric MortierAnthony A AbsalomLuc Foubert

Optimizing intravenous drug administration by applying pharmacokinetic/pharmacodynamic concepts

Michel StruysM SahinovicBJ LichtenbeltHEM VereeckeAR Absalom

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Pressure monitoring during neuroendoscopy : new insights

Frank DewaeleAlain KalmarKoen Van CanneytH VereeckeA AbsalomJacques CaemaertMichel StruysDirk Van Roost

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

2010

AQUAVAN injection, a water-soluble prodrug of Propofol, as a bolus injection: a phase I dose-escalation comparison with DIPRIVAN, part 1: pharmacokinetics (retraction of vol 103, pg 718, 2005)

Ekaterina GibianskyMichel StruysLeonid GibianskyAnn VanlucheneJames VornovEric MortierEric BurakLucas Van Bortel

AQUAVAN injection, a water-soluble prodrug of Propofol, as a bolus injection: a phase I dose-escalation comparison with DIPRIVAN, part 2: pharmacodynamics and safety (Retraction of vol 103, pg 730, 2005)

Michel StruysAnn VanlucheneEkaterina GibianskyLeonid GibianskyJames VornovEric MortierLucas Van Bortel

Assessment of the depth of anesthesia based on symbolic dynamics of the EEG

Nadine TupaikaMontserrat VallverduMathieu JospinErik W JensenMichel StruysHUGO VEREECKEA VossP Caminal

Composite Variability Index (CVI) Increases in Response to Noxious Stimuli Reflect Patient Responses

Michel StruysBJORN HEYSEChandran V Seshagiri

Definition of a new composite AEP and EEG index for monitoring the level of consciousness

Erik Weber JensenHUGO VEREECKEBarbara WylerCarmen GonzalezMichel Struys

Erroneously Published Fospropofol Pharmacokinetic-Pharmacodynamic Data and Retraction of the Affected Publications

Michel StruysJ FechnerJ SchuttlerH Schwilden

A1 Journal Article in ANESTHESIOLOGY

Influence of steep Trendelenburg position and CO2 pneumoperitoneum on cardiovascular, cerebrovascular, and respiratory homeostasis during robotic prostatectomy

Alain KalmarL FoubertJFA HendrickxA MottrieA AbsalomEric MortierMichel Struys

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Muscle potentials evoked by magnetic stimulation of the sciatic nerve in unilateral sciatic nerve dysfunction

Iris Van SoensMichel StruysLuc Van Ham

A1 Journal Article in JOURNAL OF SMALL ANIMAL PRACTICE

Noxious stimulation response index: a novel anesthetic state index based on hypnotic-opioid interaction

Martin LuginbuhlPeter M SchumacherPascal VuilleumierHUGO VEREECKEBjorn HeyseThomas W BouillonMichel Struys

A1 Journal Article in ANESTHESIOLOGY

Propofol and Remifentanil differentially modulate frontal electroencephalographic activity

David TJ LileyNicholas C SinclairTarmo LippingBjorn HeyseHUGO VEREECKEMichel Struys

A1 Journal Article in ANESTHESIOLOGY

Requested retraction of six studies on the PK/PD and Tolerability of Fosprofol

Michel StruysJörg FechnerJürgen SchüttlerHelmut Schwilden

A1 Journal Article in Anesthesia and Analgesia

Requested retraction of six studies on the PK/PD and tolerability of fospropofol

Michel StruysJ FechnerJ SchuttlerH Schwilden

A1 Journal Article in EUROPEAN JOURNAL OF ANAESTHESIOLOGY

Study of the time course of the clinical effect of propofol compared with the time course of the predicted effect-site concentration : performance of three pharmacokinetic-dynamic models

Marc CoppensJURGEN VAN LIMMENThomas SchniderBarbara WylerSjoert BonteFrank DewaeleMichel StruysHUGO VEREECKE

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

The performance of compartmental and physiologically based recirculatory pharmacokinetic models for Propofol: a comparison using bolus, continuous, and target-controlled infusion data

Kenichi MasuiRichard N UptonAnthony G DoufasJohan F CoetzeeTomiei KazamaEric MortierMichel Struys

A1 Journal Article in ANESTHESIA AND ANALGESIA

2009

Comparing index of Consciousness and Bispectral Index during Propofol Induction

TIM MELSBarbara WylerJean-Pierre Kalala OkitoMichel StruysHUGO VEREECKE

Comparing index of consciousness and bispectral index during propofol recovery

TIM MELSBarbara WylerJean-Pierre Kalala OkitoMichel StruysHUGO VEREECKE

Comparison of contemporary EEG derived depth of anesthesia monitors with a 5 step validation process

Bjorn HeyseBARBARA VAN OOTEGHEMBarbara WylerMichel StruysLuc HerregodsHUGO VEREECKE

A2 Journal Article in ACTA ANAESTHESIOLOGICA BELGICA

EPSAC-controlled anesthesia with online gain adaptation

Jorge Niño CastañedaRobain De Keyser. SyafiieClara-Mihaela IonescuMichel Struys

A1 Journal Article in INTERNATIONAL JOURNAL OF ADAPTIVE CONTROL AND SIGNAL PROCESSING

Early phase pharmacokinetics but not pharmacodynamics are influenced by propofol infusion rate

Kenichi MasuiMarimo KiraTomiei KazamaSatoshi HagihiraEric MortierMichel Struys

A1 Journal Article in Anesthesiology

Effects of sedative and hypnotic drug combinations on transcranial magnetic motor evoked potential, bispectral index and ARX-derived auditory evoked potential index in dogs

Iris Van SoensMichel StruysIngeborgh PolisMulenda TshamalaHeidi NolletSofie BhattiLuc Van Ham

A1 Journal Article in VETERINARY JOURNAL

Influence of an increased intracranial pressure on cerebral and systemic haemodynamics during endoscopic neurosurgery : an animal model

Alain KalmarGaspard De LeyC. Van den BroeckeJozef Van AkenMichel StruysMarleen PraetEric Mortier

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Magnetic stimulation of the nervous system in dogs and cats

Iris Van SoensLuc Van HamMichel StruysIngeborgh Polis

Magnetic stimulation of the radial nerve in dogs and cats with brachial plexus trauma: a report of 53 cases

Iris Van SoensMichel StruysIngeborgh PolisSofie BhattiSofie Van MeervenneValentine MartléHeidi NolletMulenda TshamalaAn VanhaesebrouckLuc Van Ham

A1 Journal Article in VETERINARY JOURNAL

Manual Versus Target-Controlled Infusion Remifentanil Administration in Spontaneously Breathing Patients

Anneliese MoermanLuc HerregodsMartine De VosEric MortierMichel Struys

A1 Journal Article in Anesthesia and Analgesia

Noxious Stimulation Response Index (NSRI): Validation of a Novel Anesthetic Depth Index

Martin LuginbuehlPeter SchumacherHUGO VEREECKEBjorn HeyseMichel Struys

Performance of propofol pharmacokinetic models

FLOOR MARTENSKenichi MasuiRichard UptonAnthony DoufasJohan CoetzeeEric MortierMichel Struys

Pharmacokinetic models for propofol-defining and illuminating the devil in the detail

A.R. AbsalomV. ManiTom De SmetMichel Struys

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Pharmacology in the obese: impact on laparoscopy

A2 Journal Article in ACTA ANAESTHESIOLOGICA BELGICA

Remifentanil Closed-Loop Delivery Based on the Difference between Response Entropy and State Entropy

Donald MathewsPasquale CirulloKathleen ParkMichel StruysTom De Smet

Response surface modeling of the interaction between propofol and sevoflurane

Peter M SchumacherJan DosscheEric MortierMartin LuginbühlThomas BouillonMichel Struys

A1 Journal Article in ANESTHESIOLOGY

Tramadol IV: influence of dose and dose intervals on the therapeutic accuracy and side effects when used for postoperative pain relief after ambulatory surgery

DIETER DEVRIESEBARBARA VANDERVENNETLiesbet Van PraetMarc CoppensEric MortierMichel Struys

2008

Accuracy and clinical feasibility of a new Bayesian-based closed-loop control system for propofol administration using the BIS as a controlled variable

Bjorn HeyseTom De SmetMartine NeckebroekKRISTOF VAN DEN HAUWESJOERT BONTEEric MortierMichel Struys

An assessment of computer-assisted personalized sedation: a sedation delivery system to administer propofol for gastrointestinal endoscopy

D.J. PiambiancoC.J. WhittenAnneliese MoermanMichel StruysJF Martin

A1 Journal Article in GASTROINTESTINAL ENDOSCOPY

Comparison of oesophageal temperature characteristics obtained in patients kept warm peroperatively by the kanmed warmcloud body warming device and the Bair Hugger Temperature Management Unit

STEPHANIE VAN PETEGHEMK De JonghJONAS VAN DOORSLAERMoustapha HamdiMichel StruysKOEN REYNTJENS

Comparison of the ability of two pharmacokinetic-dynamic models to maintain a predicted effect-site concentration of propofol compatible with loss of consciousness

JURGEN VAN LIMMENHUGO VEREECKEMarc CoppensEric MortierMichel Struys

Does the AEPmonitor/2 volume controller improves the detection of mid-latency auditory evoked potentials during propofol anaesthesia?

Barbara WylerHUGO VEREECKEEW JensenM JospinMichel Struys

Intraarticular Tramadol or "Hot Chili Peppers"? Reply

Ahed ZeidanMichel Struys

A1 Journal Article in ANESTHESIA AND ANALGESIA

Intraarticular Tramadol-Bupivacaine Combination Prolongs the Duration of Postoperative Analgesia After Outpatient Arthroscopic Knee Surgery

Ahed ZeidanRida KassemNezih NahlehHilal MaalikiMohamad El-KatibMichel StruysAnis Baraka

A1 Journal Article in ANESTHESIA AND ANALGESIA

Long-term pressure monitoring with arterial applanation tonometry : a non-invasive alternative during clinical intervention?

Koen S MatthysAlain KalmarMichel StruysEric MortierAlberto P AvolioPatrick SegersPascal Verdonck

A2 Journal Article in TECHNOLOGY AND HEALTH CARE

Magnetic stimulation of peripheral nerves in dogs: A pilot study

Iris Van SoensIngeborgh PolisJ. NijsMichel StruysSofie BhattiLuc Van Ham

A1 Journal Article in VETERINARY JOURNAL

Mixed effect modeling in analgesia trials

S.L. ShaferMichel Struys

Editorial material

Performance of the Marsh and Schnider pharmacokinetic-dynamic model to target a clinical steady-state, when using effect-site controlled titration of propofol.

Marc CoppensHUGO VEREECKEJURGEN VAN LIMMENT. SchniderMichel Struys

Perioperative temperature management. Comparison of a forced air warming device and a dynamic air mattress device in plastic surgery

KOEN REYNTJENSK. De JonghStan MonstreyMichel StruysEric Mortier

Robust predictive control strategy applied for propofol dosing using BIS as a controlled variable during anesthesia

Clara-Mihaela IonescuRobain De KeyserBC TORRICOT DE SMETMichel StruysJE NORMEY-RICO

A1 Journal Article in IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Simulated drug administration: An emerging tool for teaching clinical pharmacology during anesthesiology training

Michel StruysT. De SmetEric Mortier

A1 Journal Article in CLINICAL PHARMACOLOGY & THERAPEUTICS

Study on the optimisation of anaesthetic and analgesic drug administration in obese patients

Luc De BaerdemaekerMichel StruysEric Mortier

The Dynamic Relationship Between End-Tidal Sevoflurane Concentrations, Bispectral Index, and Cerebral State Index in Children

R. FuentesL. CortinezMichel StruysA. DelfinoH. Munoz

A1 Journal Article in ANESTHESIA AND ANALGESIA

The Year in Anaesthesia and Critical Care, volume 2

The accuracy and clinical feasibility of a new Bayesian-based closed-loop control system for propofol administration using the bispectral index as a controlled variable

Tom De SmetMichel StruysMartine NeckebroekKRISTOF VAN DEN HAUWESJOERT BONTEEric Mortier

A1 Journal Article in ANESTHESIA AND ANALGESIA

The effect of rapid increase in desflurane and sevoflurane concentrations on spirometry in humans during balanced anesthesia with remifentanil

Annick WillemsLuc De BaerdemaekerAlain KalmarMichel Struys

A2 Journal Article in ACTA ANAESTHESIOLOGICA BELGICA

The effect of wound instillation of a novel purified capsaicin formulation on postherniotomy pain: a double-blind, randomized, placebo-controlled study

E. AasvangJ. HansenJ. MalmstromT. AsmussenD. GennevoisMichel StruysH. Kehlet

A1 Journal Article in Anesthesia and Analgesia

The effects of rapid increases in desflurane and sevoflurane concentrations on spirometry in humans during balanced anesthesia with remifentanil

A WillemsLuc De BaerdemaekerAlain KalmarMichel Struys

The infuence of the Administration Rate on the Front-End Kinetics of Propofol

Kenichi MasuiTomiei KazamaEric MortierMichel Struys

2007

A new method for evaluating the performance of depth-of-hypnosis indices - the D-value

T. LippingR. FerenetsEric MortierMichel Struys

An overview of TCI & TIVA

A ABSALOMMichel Struys

Behaviour of entropy/complexity measures of the electroencephalogram during propofol-induced sedation: dose-dependent effects of remifentanil

Rain FerenetsANN VANLUCHENETarmo LippingBJORN HEYSEMichel Struys

A1 Journal Article in ANESTHESIOLOGY

Changes in a surgical stress index in response to standardized pain stimuli during propofol-remifentanil infusion

Michel StruysCAROLINE VANPETEGHEMM HuikuK UutelaNico BlyaertEric Mortier

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Comparison of two compartmental pharmacokinetics models to predict the time course of propofol plasma concentration during the first 5 minutes after a bolus injection

Hilde Van KerckhovenEric MortierJan Van BocxlaerMichel Struys

A2 Journal Article in ACTA ANAESTHESIOLOGICA BELGICA

Depth of anesthesia index using cumulative power spectrum

M. JospinP. CaminalEW. JensenM. VallverduMichel StruysHUGO VEREECKEDT Kaplan

Detrended fluctuation analysis of EEG as a measure of depth of anesthesia

Mathieu JospinPere CaminalErik W JensenHector LitvanMontserrat VallverdúMichel StruysHUGO VEREECKEDaniel T Kaplan

A1 Journal Article in IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Do we need inhaled anaesthetics to blunt arousal and haemodynamic responses to intubation after intravenous induction with propofol, remifentanil and rocuronium?

D Ndjekembo ShangoMarc CoppensLinda VersichelenEric MortierMichel Struys

A2 Journal Article in ACTA ANAESTHESIOLOGICA BELGICA

Do we need inhaled anaesthetics to blunt arousal, haemodynamic responses to intubation after i.v. induction with propofol, remifentanil, rocuronium?

Marc CoppensLinda VersichelenEric MortierMichel Struys

A2 Journal Article in BJA. BRITISH JOURNAL OF ANAESTHESIA (SOUTH AFRICAN ED.)

Effect site: who needs it?

J SneydA Rigby-JonesMichel Struys

Editorial material

Estimation of optimal modeling weights for a Bayesian-based closed-loop system for propofol administration using the bispectral index as a controlled variable: a simulation study

Tom De SmetMichel StruysScott GreenwaldEric MortierSteven L Shafer

A1 Journal Article in ANESTHESIA AND ANALGESIA

Evaluation of the pressure characteristics of the new Kanmed Warmcloud body warming device in healthy volunteers

Sophie VanherpenPIETER COSAERTKOEN REYNTJENSA ChafaiTom DefloorMichel Struys

A2 Journal Article in ACTA ANAESTHESIOLOGICA BELGICA

Feasibility study for the administration of remifentanil based on the difference between response entropy and state entropy

DM MathewsPM CirulloMichel StruysTom De SmetRJ MalikCL ChangGG Neuman

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Influence of administration rate on propofol plasma - Effect site equilibration

Michel StruysMarc CoppensN DE NEVEEric MortierAG DOUFASJan Van BocxlaerSL SHAFER

A1 Journal Article in ANESTHESIOLOGY

Influence of intraoperative opioid on postoperative pain and pulmonary function after laparoscopic gastric banding: remifentanil TCI vs sufentanil TO in morbid obesity

Luc De BaerdemaekerSTEFAN JACOBSPiet PattynEric MortierMichel Struys

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Magnetic stimulation of the radial nerve in dogs and cats with unilateral brachial plexus trauma: 53 cases

Iris Van SoensMichel StruysIngeborgh PolisSofie BhattiSofie Van MeervenneValentine MartléHeidi NolletMulenda TshamalaAn VanhaesebrouckLuc Van Ham

Multi-level approach to anaesthetic effects produced by sevoflurane or propofol in humans, 1: BIS and blink reflex

J MourisseJ LerouMichel StruysM ZwartsL Booij

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Multi-level approach to anaesthetic effects produced by sevoflurane or propofol in humans, 2: BIS and tetanic stimulus-induced withdrawal reflex

J MourisseJ LerouMichel StruysM ZwartsL Booij

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Recent advances in composite AEP/EEG indices for estimating hypnotic depth during general anesthesia

Erik Weber JensenPablo MartinezHector LitvanHUGO VEREECKEBernardo RodriguezMichel Struys

Bookchapter in Handbook of neural engineering

Response surface modeling of the interaction between propofol and sevoflurane

Jan DosschePeter M SchumacherMartin LuginbühlMichel StruysThomas Bouillon

Response surface modeling of the interaction between propofol and sevoflurane

Peter M SchumacherJan DosscheMartin LuginbühlMichel StruysThomas W Bouillon

Reversal of rocuronium-induced neuromuscular block with the novel drug sugammadex is equally effective under maintenance anesthesia with propofol or sevoflurane

Bernard F VanackerKarel M VermeyenMichel StruysHenk RietbergenEugene VandermeerschVera SaldienAlain KalmarMartine E Prins

A1 Journal Article in ANESTHESIA AND ANALGESIA

Role play sessions in pharmacotherapeutic counselling: evaluation by students

Lucas Van BortelFabienne De BoeckMichel StruysPeter De PaepeThierry ChristiaensIsabelle FabryAn De SutterMirko PetrovicRobert Vander Stichele

Single-dose crossover pharmacokinetic/pharmacodynamic study of fospropofol vs propofol in healthy volunteers

A. ShahJ. FechnerMichel StruysB Mistry

Study of the level of anesthesia compatible with no detection of brainstem and mid-latency auditory evoked potentials: comparison between a fixed versus a variable acoustic stimulus volume

Patricia CouckeHUGO VEREECKEMathieu JospinErik Weber JensenMichel Struys

Take It to the Limit 1 (One More Time) This Editorial View accompanies the following article: Struys MMRF, Coppens MJ, De Neve N, Mortier EP, Doufas AG, Van Bocxlaer JFP, Shafer SL: Influence of administration rate on propofol plasma–effect site equilibration. Anesthesiology 2007; 107:386–96. Accepted for publication June 20, 2007. The author is not supported by, nor maintains any financial interest in, any commercial activity that may be associated with the topic of this article. Record Number: 000111498

D FISCHERMichel Struys

A2 Journal Article in Anesthesiology

2006

A new spectral index for assessing depth of anesthesia based on the cumulative power spectrum of the EEG

M JospinEW JensenP CaminalDT KaplanHUGO VEREECKEMichel Struys

A pilot study on heart rate variability (HRV) during an inhalation bolus technique with sevoflurane of desflurane (preliminary results)

G TchounkachuANN BAELEAlain KalmarMichel StruysLuc De Baerdemaeker

Cerebral state index during propofol anesthesia : a comparison with the bispectral index and the A-line ARX index

Erik W JensenHector LitvanMiren RevueltaBernardo E RodriguezPere CaminalPablo MartinezHUGO VEREECKEMichel Struys

A1 Journal Article in ANESTHESIOLOGY

Changes of a surgical stress index in response to standardized pain stimuli during propofol-remifentanil

CAROLINE VANPETEGHEMM HuikuK UutelaEric MortierMichel Struys

Changes of a surgical stress index in response to standarized pain stimuli during propofol-remifentanil infusion

Nico BlyaertCAROLINE VANPETEGHEMM HuikuK UutelaEric MortierMichel Struys

Closed loops in anaesthesia

Michel StruysEric MortierTom De Smet

A2 Journal Article in BEST PRACTICE AND RESEARCH CLINICAL ANAESTHESIOLOGY

Comparison between a fixed versus a variable acoustic stimulus volume for optimizing the detection of mid-latency auditory evoked potentials during propofol anesthesia

HUGO VEREECKEMathieu JospinErik JensenPere CaminalMichel Struys

Depth of anaesthesia monitoring: what's available, what's validated and what's next?

J BruhnPS MylesR SneydMichel Struys

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Do we need inhaled anaesthetics to blunt arousal, haemodynamic responses to intubation after i.v. induction with propofol, remifentanil, rocuronium?

Marc CoppensLinda VersichelenEric MortierMichel Struys

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Drug interactions involving continuous and quantal responses. Identifiability of parameters

T BOUILLONMichel StruysD LEIBUNDGUTM LUGINBUEHLP SCHUMACHER

EPSAC predictive control applied to drug dosing during anesthesia

B CLAURE-TORRICOClara-Mihaela IonescuTom De SmetRobain De KeyserMichel StruysJ NORMEY-RICO

Effects and monitoring of sedation and anesthesia for transcranial magnetic motor evoked potentials in dogs

Iris Van SoensMichel StruysIngeborgh PolisMulenda TshamalaLuc Van Ham

Feasibility assessment of a sedation delivery system to administer propofol for GI endoscopy

ANNELIESE MOERMAND PAMBIANCOJ RORIEJ MARTINMichel Struys

Pharmacokinetic principles

Michel StruysAlain KalmarPeter De Paepe

Bookchapter in Anaesthesia Science

Postoperative results after desflurane or sevoflurane combined with remifentanil in morbidly obese patients

Luc De BaerdemaekerSTEFAN JACOBSNADIA DEN BLAUWENPiet PattynLuc HerregodsEric MortierMichel Struys

A1 Journal Article in OBESITY SURGERY

The effects of ketamine and rocuronium on the A-line® auditory evoked potential index, bispectral index, and spectral entropy monitor during steady state propofol and remifentanil anesthesia

HUGO VEREECKEAnn VanlucheneEric MortierKarel EveraertMichel Struys

A1 Journal Article in ANESTHESIOLOGY

The effects of rocuronium and ketamine on bispectral index, A-Line auditory evoked potentials index and spectral entropy

HUGO VEREECKEAnn VanlucheneEric MortierMichel Struys

The mechanisms of carbon monoxide production by inhalational agents

MARC COPPENSLinda VersichelenGeorges RollyEric MortierMichel Struys

A1 Journal Article in ANAESTHESIA

2005

A comparison between bispectral index and three versions of the A-line auditory evoked potential to predict a calculated propofol effect-site concentration during a transition from fully awake to maxial burst suppression

Sven PicavetHUGO VEREECKEOlivier ThasEric MortierMichel Struys

A2 Journal Article in ACTA ANAESTHESIOLOGICA BELGICA

AQUAVAN (R) injection, a water-soluble prodrug of propofol as a bolus injection: A phase I dose-escalation comparison with DIPRIVAN (R) (Part 2) - Pharmacodynamics and safety

Michel StruysAnn VanlucheneE GIBIANSKYL GIBIANSKYJ VORNOVEric MortierLucas Van Bortel

A1 Journal Article in ANESTHESIOLOGY

AQUAVAN((R)) injection, a water-soluble prodrug of propofol as a bolus injection: A phase I dose-escalation comparison with DIPRIVAN((R)) (Part 2) - Pharmacodynamics and safety. Vol. 103

Michel StruysAnn VanlucheneE GIBIANSKYL GIBIANSKYJ VORNOVEric MortierLucas Van Bortel

AQUAVANO (R) injection, a water-soluble prodrug of propofol, as a bolus injection: A phase I dose-escalation comparison with DIPRIVAN (R) (Part 1) - Pharmacokinetics

E GIBIANSKYMichel StruysL GIBIANSKYAnn VanlucheneJ VORNOVEric MortierE BURAKLucas Van Bortel

A1 Journal Article in ANESTHESIOLOGY

AQUAVANO((R)) injectjon, a water-soluble prodrug of propofol as a bolus injection: A phase I dose-escalation comparison with DIPRIVAN((R)) (Part 1) - Pharmacokinetics. Vol. 103

E GIBIANSKYMichel StruysAnn VanlucheneL GIBIANSKYJ VORNOVEric MortierE BURAKLucas Van Bortel

An overview of Target Controlled infusions and total intravenous anaesthesia

A ABSALOMMichel Struys

Anaesthesia & Critical Care

Depth of anaesthesia monitoring

Hugo VereeckeMichel Struys

Bookchapter in Anaesthesia & Critical Care

Detrended Fluctuation Analysis of the EEG for Assessing Depth of Anesthesia.

M JOSPINE JENSENB RODRIGUEZH LITVANMichel Struys

Exceptional clinical observation : total brain ischemia during normal intracranial pressure readings caused by obstruction of the outflow of a neuroendoscope

Alain KalmarJozef Van AkenMichel Struys

A1 Journal Article in JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY

New composite index based on midlatency auditory evoked potential and electroencephalographic parameters to optimize correlation with propofol effect site concentration: comparison with bispectral index and solitary used fast extracting auditory evoked potential index

HUGO VEREECKEPablo Martinez VasquezErik Weber JensenOlivier ThasRudy Van den BroeckeEric MortierMichel Struys

A1 Journal Article in ANESTHESIOLOGY

Objective structured clinical examinations (OSCE’s) of pharmacotherapeutic counseling : competence assessment by teachers and students

Peter De PaepeThierry ChristiaensMirko PetrovicMichel StruysRobert Vander SticheleT De VriesLucas Van Bortel

Predictive control applied to drug dosing administration

B CLAURE-TORRICOClara-Mihaela IonescuT DE SMETRobain De KeyserMichel StruysJ NORMEY-RICO

Reversal by Org 25969 is not affected by sevoflurane compared with propofol

BF VanackerKM VermeyenMichel StruysH RietbergenE VandermeerschV SaldienAlain KalmarME Prins

Role play sessions in pharmacotherapeutic counselling: evaluation by students

Peter De PaepeMirko PetrovicThierry ChristiaensMichel StruysRobert Vander SticheleT de VriesLucas Van Bortel

Role play sessions in pharmacotherapeutic counselling: evaluation by students

Peter De PaepeT CHRISTIAENSMirko PetrovicMichel StruysR VAN DER STICHELET DE VRIESLucas Van Bortel

Time course of inhaled anaesthetic drug delivery using a new multifunctional closed-circuit anaesthesia ventilator: in vitro comparison with a classical anaesthesia machine

Michel StruysAlain KalmarLuc De BaerdemaekerEric MortierGeorges RollyJ ManigelW Buschke

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Value of Cushing reflex as warning sign for brain ischaemia during neuroendoscopy

Alain KalmarJozef Van AkenJacques CaemaertEric MortierMichel Struys

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

What is new in anaesthetic pharmacology

Bookchapter in The year in anaesthesia and critical Care

2004

Analisis de fluctuaciones sin tendendies del EEG como medida de la profundidad anestesica

M JOSPINP CAMINALE JENSENH LITVANM VALLERDUHugo VereeckeMichel Struys

Analysis of bispectral index, state and response entropy values upon emergence from anesthesia in patients anaesthetized with propofol or sevoflurane

P LambertE JunkeC MeistelmanMichel StruysD Longrois

Bis, spectral entropy and predicted propofol concentrations are useful to measure patient responsiveness during anesthesia with propofol and remifentanil

Mieke GorissenMichel StruysANN VANLUCHENEEric Mortier

A2 Journal Article in ACTA ANAESTHESIOLOGICA BELGICA

Blood-sparing effect of Tranexamine acid in major spinal surgery: a prospective doubleblind study

C VandammeGUDRUN BOSSUYTLuc HerregodsMichel StruysDORINE DYZERS

A2 Journal Article in ACTA ANAESTHESIOLOGICA BELGICA

Closed loop Anaesthesia

Michel StruysT DE SMETEric Mortier

Electro-encephalographic surrogate measures fail to describe the pharmacodynamic interaction between ketamine and propofol.

Michel StruysHugo VereeckeEric Mortier

Medida de la profundidad anestetica mediante analisis de fluctuaciones sin tendencies de la senal electroencefalografica

M JOSPINP CAMINALE JENSENH LITVANM VALLVERDUHugo VereeckeMichel Struys

Monitorizacion de la profundad anestesia mediante analisis de fluctuaciones sin tendencies de la senal electroencefalografica

M JOSPINP CAMINALE JENSENH LITVANM VALLVERDUHugo VereeckeMichel Struys

Performance evaluation of two published closed-loop control systems using bispectral index monitoring: a simulation study

Michel StruysTom De SmetScott GreenwaldAnthony R AbsalomServaas BingéEric Mortier

A1 Journal Article in ANESTHESIOLOGY

Pharmacodynamics of AQUAVAN® bolus injection: a phase I, dose escalation comparison with DIPRIVAN®

ANN VANLUCHENELucas Van BortelJ VornovE GibianskyMichel Struys

Pharmacokinetics and pharmacodynamics : essential guide for anesthetic drugs administration

Luc De BaerdemaekerEric MortierMichel Struys

Bookchapter in Morbid obesity : peri-operative management

Pharmacokinetics and pharmacodynamics of AQUAVAN® bolus injection: a population PK/PD model®

E GibianskyMichel StruysL Gibiansky

Pharmacokinetics in obese patients

Luc De BaerdemaekerEric MortierMichel Struys

A2 Journal Article in CONTINUING EDUCATION IN ANAESTHESIA CRITICAL CARE & PAIN

Pitfalls and challenges when assessing the depth of hypnosis during general anaesthesia by clinical signs and electronic indices

EW JensenH LitvanMichel StruysP Martinez Vazquez

A1 Journal Article in ACTA ANAESTHESIOLOGICA SCANDINAVICA

Production of compound A and carbon monoxide in circle systems : an in vitro comparison of two carbon dioxide absorbents

Michel StruysMPLA BoucheGeorges RollyYDI VandevivereDorine DyzersWim GoeteynLinda VersichelenJan Van BocxlaerEric Mortier

A1 Journal Article in ANAESTHESIA

Recovery after desflurane or sevoflurane anaesthesia combined with remifentanil in morbiaty obese patients

Stefan JacobsLuc De BaerdemaekerMichel StruysNADIA DEN BLAUWENEric Mortier

A2 Journal Article in ACTA ANAESTHESIOLOGICA BELGICA

Remifentanil used to supplement propofol does not improve quality of sedation during spontaneous respiration

Anneliese MoermanMichel StruysHugo VereeckeLuc HerregodsMartine De VosEric Mortier

A1 Journal Article in JOURNAL OF CLINICAL ANESTHESIA

Spectral entropy as an electroennopbalograpbic measure of anesthetic drug effect: a comparison with bispectral index and precessed midlatency auditory evoked response

Ann VanlucheneHUGO VEREECKEOlivier ThasEric MortierSteven LMD ShaferMichel Struys

A1 Journal Article in ANESTHESIOLOGY

Spectral entropy measurement of patient responsiveness during propofol and remifentanil: a comparison with the bispectral index

ANN VANLUCHENEMichel StruysBJORN HEYSEEric Mortier

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

The influence of propofol administration rate on the Ke0 value, preliminary results

Michel StruysNIKOLAAS DE NEVET DE SMETEric Mortier

Two new CO2 absorbents (Drägersorb® Free and Amsorb Plus®): an in vitro comparison for possible production of Compound A and Carbon monoxide

Y VandevivereMichel StruysM BouchéLinda VersichelenGeorges RollyEric Mortier

A2 Journal Article in ACTA ANAESTHESIOLOGICA BELGICA

2003

A comparison of bispectral index and ARX-derived auditory evoked potential index in measuring the clinical interaction between ketamine and propofol anaesthesia

Hugo VereeckeMichel StruysEric Mortier

A1 Journal Article in ANAESTHESIA

Ability of the bispectral index, autoregressive modelling with exogenous input-derived auditory evoked potentials, and predicted propofol concentrations to measure patient responsiveness during anesthesia with propofol and remifentanil

Michel StruysHugo VereeckeANNELIESE MOERMANEW JENSENDAVID VERHAEGHENNIKOLAAS DE NEVEFrank DumortierEric Mortier

A1 Journal Article in ANESTHESIOLOGY

An AEP/EEG hybrid index for monitoring the hypnotic depth during general anesthesia..

E JENSENMichel StruysP VASQUEZB RODRIGUEZH LITVAN

Anaesthetic management and perioperative course of right liver-lobe donation for living- donor liver transplantation

O VinckLuc HerregodsLuc De BaerdemaekerMichel StruysRoberto TroisiBernard de HemptinneEric Mortier

A2 Journal Article in ACTA ANAESTHESIOLOGICA BELGICA

Bispectral index of Aquavan(tm )-derived propofol: population PK/PD modelling and application to an effect - controlled trial

L GIBIANSKYMichel StruysE GIBIANSKY

Cardiovascular changes during endoscopic third ventriculostomy

Jozef Van AkenMichel StruysTHIERRY VERPLANCKELUC DE BAERDEMAEKERJacques CaemaertEric Mortier

A1 Journal Article in MINIMALLY INVASIVE NEUROSURGERY

Depth of anesthesia monitors: Status quo - In reply

Michel StruysEric Mortier

A1 Journal Article in ANESTHESIOLOGY

Effect site modelling and its application in TCI

Eric MortierMichel Struys

A1 Journal Article in ADVANCES IN MODELLING AND CLINICAL APPLICATION OF INTRAVENOUS ANAESTHESIA

Medida de la profundidad anestesica mediante analisis de fluctuaciones sin tendencies de la senal electroencefalografica

M JOSPINP CAMINALE JENSENH LITVANM VALLVERDUHugo VereeckeMichel Struys

Optimization of desflurane administration in morbidly obese patients: a comparison with sevoflurane using an 'inhalation bolus' technique

LUC DE BAERDEMAEKERMichel StruysStefan JacobsNADIA DEN BLAUWENGUDRUN BOSSUYTPiet PattynEric Mortier

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Propofol versus remifentanil for monitored anaesthesia care during colonoscopy

ANNELIESE MOERMANLA FOUBERTLuc HerregodsMichel StruysDaniël De WolfDanny De LoozeMartine De VosEric Mortier

A1 Journal Article in EUROPEAN JOURNAL OF ANAESTHESIOLOGY

Simultaneous population pharmacokinetic model of AquavanTM and AquavanTM-derived propofol

L GIBIANSKYMichel StruysE GIBIANSKY

Usefulness of pressure-volume loops or monitoring extubating conditions: the spontaneous inspiratory pressure

V BosteelsLaszlo L SzegediMichel StruysEric Mortier

2002

Closed-loop control of anaesthesia

Michel StruysT De SmetEric Mortier

A2 Journal Article in CURRENT OPINION IN ANAESTHESIOLOGY

Cost-reduction analysis of propofol versus sevoflurane: maintenance of anaesthesia for gynaecological surgery using the bispectral index.

Michel StruysA SOMERSN VAN DEN EYNDELuc HerregodsD DYZERSHugo RobaysEric Mortier

A1 Journal Article in EUROPEAN JOURNAL OF ANAESTHESIOLOGY

Dose requirements and recovery profile of an infusion of cisatracurium during liver transplantation.

G CAMMUGUDRUN BOSSUYTL DE BAERDEMAEKERN DEN BLAUWENMichel StruysEric Mortier

A1 Journal Article in JOURNAL OF CLINICAL ANESTHESIA

No Compound A formation with Superia (R) during minimal-flow sevoflurane anesthesia: A comparison with Sofnolime.

Marie-Paule BoucheLinda VersichelenMichel StruysJan Van BocxlaerAndreas De LeenheerEric MortierGeorges Rolly

A1 Journal Article in ANESTHESIA AND ANALGESIA

Performance of the ARX-derived auditory evoked potential index as an indicator of anesthetic depth - A comparison with bispectral index and hemodynamic measures during propofol administration.

Michel StruysEW JENSENW SMITHNT SMITHI RAMPILFE DUMORTIERC MESTACHEric Mortier

A1 Journal Article in ANESTHESIOLOGY

Postoperative residual curarization with cisatracurium and rocuronium infusions

Guy CammuLuc De BaerdemaekerNADIA DEN BLAUWENJ-C de MeyMichel StruysEric Mortier

A1 Journal Article in EUROPEAN JOURNAL OF ANAESTHESIOLOGY

2001

Comparison of closed-loop controlled administration of propofol using bispectral index as the controlled variable versus 'standard practice' controlled administration

Michel StruysTom De SmetLinda VersichelenStijn Van de VeldeRudy Van den BroeckeEric Mortier

A1 Journal Article in ANESTHESIOLOGY

Compound A production from sevoflurane is not less when KOH-free absorbent is used in a closed-circuit lung model system.

Linda VersichelenMarie-Paule BoucheMichel StruysJan Van BocxlaerEric MortierAndreas De LeenheerGeorges Rolly

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Monitoring of depth of anaesthesia using bispectral analysis and closed-loop controlled administration of propofol

Eric MortierMichel Struys

A2 Journal Article in BEST PRACTICE & RESEARCH-CLINICAL ANAESTHESIOLOGY

Only carbon dioxide absorbents free of both NaOH and KOH do not generate compound A during in vitro closed-system sevoflurane: evaluation of five absorbents

Linda VersichelenMarie-Paule BoucheGeorges RollyJan Van BocxlaerMichel StruysAndreas De LeenheerEric Mortier

A1 Journal Article in ANESTHESIOLOGY

Quantitative determination of vapor-phase compound A in sevoflurane anesthesia using gas chromatography-mass spectrometry.

Marie-Paule BoucheJan Van BocxlaerGeorges RollyLinda VersichelenMichel StruysEric MortierAndreas De Leenheer

A1 Journal Article in CLINICAL CHEMISTRY

Target-controlled administration of inhaled anaesthetics

Michel StruysEric Mortier

A2 Journal Article in BAILLIERE'S BEST PRACTICE AND RESEARCH CLINICAL ANAESTHESIOLOGY

The man-machine interaction

Michel StruysO VinckT De SmetEric Mortier

A2 Journal Article in ACTA ANAESTHESIOLOGICA BELGICA

2000

Comparison of plasma compartment versus two methods for effect compartment-controlled target-controlled infusion for propofol.

Michel StruysT DE SMETB DEPOORTERLinda VersichelenEric MortierF DUMORTIERSL SHAFERGeorges Rolly

A1 Journal Article in ANESTHESIOLOGY

Effect site modelling and its application in TCI.

Eric MortierMichel Struys

A2 Journal Article in ACTA ANAESTHESIOLOGICA BELGICA

In vitro compound a formation in a computer-controlled closed-circuit anesthetic apparatus - Comparison with a classical valve circuit.

Linda VersichelenGeorges RollyMarie-Paule BoucheJan Van BocxlaerMichel StruysC VAN DER HERTENAndreas De LeenheerEric Mortier

A1 Journal Article in ANESTHESIOLOGY

In vitro compound a formation in a computer-controlled closed-circuit anesthetic apparatus - Comparison with a classical valve circuit. Vol. 93

Linda VersichelenGeorges RollyM BOUCHEJ VAN BOXLAERMichel StruysC VAN DER HERTENAndreas De LeenheerEric Mortier

Influence of intravenous clonidine pretreatment on anesthetic requirements during bispectral EEG-guided sevoflurane anesthesia.

C DE DEYNEMichel StruysR HEYLENR DE JONGHM VANDER LAENENL BUYSEJ DEGHISLAGEGeorges Rolly

A1 Journal Article in JOURNAL OF CLINICAL ANESTHESIA

Jugular bulb desaturations during propofol anesthesia in neurosurgical procedures.

C DE DEYNER DE JONGHR HEYLENMichel Struys

A1 Journal Article in ANESTHESIA AND ANALGESIA

New developments in cerebral monitoring

C De DeyneMichel Struys

A2 Journal Article in CURRENT OPINION IN ANAESTHESIOLOGY

Therapeutic coma or neuroprotection by anaesthetics.

Eric MortierMichel StruysLuc Herregods

A1 Journal Article in ACTA NEUROLOGICA BELGICA

1999

Influence of methane on infrared gas analysis of volatile anesthetics

Eric MortierMichel StruysLinda VersichelenGeorges Rolly

A2 Journal Article in ACTA ANAESTHESIOLOGICA BELGICA

1998

Clinical usefulness of the bispectral in index for titrating propofol target effect-site concentration.

Michel StruysLinda VersichelenG BYTTEBIEREric MortierA MOERMANGeorges Rolly

A1 Journal Article in ANAESTHESIA

Closed loop controlled administration of propofol using bispectral analysis.

Eric MortierMichel StruysT DE SMETLinda VersichelenGeorges Rolly

A1 Journal Article in ANAESTHESIA

Comparison of spontaneous frontal EMG, EEG power spectrum and bispectral index to monitor propofol drug effect and emergence.

Michel StruysLinda VersichelenEric MortierD RYCKAERTJC DE MEYC DE DEYNEGeorges Rolly

A1 Journal Article in ACTA ANAESTHESIOLOGICA SCANDINAVICA

Datex AS/(3) record keeping - using the ADU gas control and vaporising principles

G ROLLYMichel StruysL VERSICHELEN

P1 Journal Article in STATE-OF-THE-ART TECHNOLOGY IN ANESTHESIA AND INTENSIVE CARE

Haemodynamic and electroencephalographic response to insertion of a cuffed oropharyngeal airway: comparison with the laryngeal mask airway.

Linda VersichelenMichel StruysE CROMBEZK FONCKEric MortierGeorges Rolly

A1 Journal Article in BRITISH JOURNAL OF ANAESTHESIA

Influence of anaesthesia on defibrillation threshold.

A MOERMANLuc HerregodsRené TavernierLuc JordaensMichel StruysGeorges Rolly

A1 Journal Article in ANAESTHESIA

Influence of pre-anaesthetic medication on target propofol concentration using a 'Diprifusor' TCI system during ambulatory surgery.

Michel StruysLinda VersichelenGeorges Rolly

A1 Journal Article in ANAESTHESIA

Jugular bulb oximetry: review on a cerebral monitoring technique

C De DeyneJozef Van AkenJohan DecruyenaereMichel StruysFrancis Colardyn

A2 Journal Article in ACTA ANAESTHESIOLOGICA BELGICA

Objective structured clinical examinations (OSCE’s) of pharmacotherapeutic counseling: competence assessment by teachers and students

Peter De PaepeT CHRISTIAENSMirko PetrovicMichel StruysR VAN DER STICHELET DE VRIESLucas Van Bortel

Study of the optimalization of anaesthetic-hypnotic drug administration during anaesthesia and sedation

Michel StruysGeorges RollyLinda Versichelen

Use of continuous bispectral EEG monitoring to assess depth of sedation in ICU patients.

C DE DEYNEMichel StruysJohan DecruyenaereJ CREUPELANDTE HOSTEFrancis Colardyn

A1 Journal Article in INTENSIVE CARE MEDICINE

1997

Comparison of computer-controlled administration of propofol with two manually controlled infusion techniques

Michel StruysLinda VersichelenOlivier ThasLuc HerregodsGeorges Rolly

A1 Journal Article in ANAESTHESIA

Limited intentional normovolemic hemodilution: ST-segment changes and use of homologous blood products in patients with left main coronary artery stenosis

Luc HerregodsAnneliese MoermanLuc FoubertNADIA DEN BLAUWENEric MortierJan PoelaertMichel Struys

A1 Journal Article in JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA

1996

Comparison of computer-controlled propofol administration with two manual infusion methods

Michel StruysLinda VersichelenOlivier ThasLuc HerregodsGeorges Rolly

Closed-Loop Delivery of Remifentanil Based on the Difference between State and Response Entropy. Vol. 107

D MATHEWSA MELLORK ROSSMichel StruysG NEUMAN

Differential PK/PD of Propofol after Intravenous Fospropofol and Diprivan in Healthy Subjects. Vol. 107

A SHAHJ FECHNERMichel StruysB MISTRY

Feasibility assessment of computer-assisted personalized sedation: A sedation delivery system to administer propofol for gastrointestinal endoscopy. Vol. 101

D PAMBIANCOC WHITTENANNELIESE MOERMANMichel StruysJ MARTINJ MCRORIE