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Onderzoeker
Maarten De Smet
Profiel
Projecten
Publicaties
Activiteiten
Prijzen & Erkenningen
37
Resultaten
2023
Arrhythmogenic consequences of connexin 43 hemichannel opening in the heart : an experimental and computational study
Maarten De Smet
Luc Leybaert
Karin Sipido
Proefschrift
2023
Connexin hemichannels as candidate targets for cardioprotective and anti-arrhythmic treatments
Luc Leybaert
Maarten De Smet
Alessio Lissoni
Rosalie Allewaert
H. Llewelyn Roderick
Geert Bultynck
Mario Delmar
Karin R. Sipido
Katja Witschas
A1
Artikel in een tijdschrift
in
JOURNAL OF CLINICAL INVESTIGATION
2023
Trends in diagnosis, referral, red flag onset, patient profiles and natural outcome of de novo cardiac amyloidosis and their multidisciplinary implications
Philippe Debonnaire
Mathias Claeys
Maarten De Smet
Sander Trenson
Michelle Lycke
Catherine Demeester
Jan Van Droogenbroeck
An S. De Vriese
Kristof Verhoeven
Nikolaas Vantomme
et al.
A1
Artikel in een tijdschrift
in
ACTA CARDIOLOGICA
2023
2022
An unexpected cause of constipation and abdominal distension in COPD
Maarten De Smet
Eric Derom
Guy Joos
Redactioneel materiaal
2022
Atrial tachycardia occurring after a prior atrial fibrillation ablation procedure : does non-inducibility matter?
L O'Neill
B De Becker
Maarten De Smet
JB Le Polain De Waroux
R Tavernier
Mattias Duytschaever
S Knecht
A1
Artikel in een tijdschrift
in
FRONTIERS IN CARDIOVASCULAR MEDICINE
2022
Case report : hemorrhagic fever with renal syndrome presenting as hemophagocytic lymphohistiocytosis
Maarten De Smet
Simon Bogaert
Alexander Schauwvlieghe
Amélie Dendooven
Pieter Depuydt
Patrick Druwé
A1
Artikel in een tijdschrift
in
FRONTIERS IN MEDICINE
2022
SARS-CoV-2-related multisystem inflammatory syndrome in adult complicated by myocarditis and cardiogenic shock
Maarten De Smet
Jan Fierens
Lander Vanhulle
Yannick Vande Weygaerde
Thomas Malfait
Daniel Devos
Filomeen Haerynck
Sofie Gevaert
A1
Artikel in een tijdschrift
in
ESC HEART FAILURE
2022
Targeting gliovascular connexins prevents inflammatory blood-brain barrier leakage and astrogliosis
Marijke De Bock
Maarten De Smet
Stijn Verwaerde
Hanane Tahiri
Steffi Schumacher
Valérie Van Haver
Katja Witschas
Christian Steinhäuser
Nathalie Rouach
Roosmarijn Vandenbroucke
et al.
A1
Artikel in een tijdschrift
in
JCI INSIGHT
2022
2021
Cx43 hemichannel microdomain signaling at the intercalated disc enhances cardiac excitability
Maarten De Smet
Alessio Lissoni
Timur Nezlobinskii
Nan Wang
Eef Dries
Marta Pérez-Hernández
Xianming Lin
Matthew Amoni
Tim Vervliet
Katja Witschas
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF CLINICAL INVESTIGATION
2021
RyR2 regulates Cx43 hemichannel intracellular Ca2+-dependent activation in cardiomyocytes
Alessio Lissoni
Paco Hulpiau
Tânia Martins-Marques
Nan Wang
Geert Bultynck
Rainer Schulz
Katja Witschas
Henrique Girao
Maarten De Smet
Luc Leybaert
A1
Artikel in een tijdschrift
in
CARDIOVASCULAR RESEARCH
2021
2020
Cx43 channels and signaling via IP3/Ca2+, ATP, and ROS/NO propagate radiation-induced DNA damage to non-irradiated brain microvascular endothelial cells
Delphine Hoorelbeke
Elke Decrock
Maarten De Smet
Marijke De Bock
Benedicte Descamps
Valérie Van Haver
Tinneke Delvaeye
Dmitri Krysko
Christian Vanhove
Geert Bultynck
et al.
A1
Artikel in een tijdschrift
in
CELL DEATH & DISEASE
2020
Gap19, a Cx43 hemichannel inhibitor, acts as a gating modifier that decreases main state opening while increasing substate gating
Alessio Lissoni
Nan Wang
Timur Nezlobinskii
Maarten De Smet
Alexander Panfilov
Nele Vandersickel
Luc Leybaert
Katja Witschas
A1
Artikel in een tijdschrift
in
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2020
2019
Blocking connexin43 hemichannels protects mice against tumour necrosis factor-induced inflammatory shock
Tinneke Delvaeye
Maarten De Smet
Stijn Verwaerde
Elke Decrock
Aleksandra Czekaj
Roosmarijn Vandenbroucke
Kelly Lemeire
Amanda Gonçalves
Wim Declercq
Peter Vandenabeele
et al.
A1
Artikel in een tijdschrift
in
SCIENTIFIC REPORTS
2019
Intercalated discs : specialized cytoskeletal anchors in cardiac muscle
Jolanda van Hengel
Maarten De Smet
Anna Kremer
Saskia Lippens
Marjolijn Renard
Christophe Ampe
Bieke Vanslembrouck
C3
Conferentie
2019
2018
Activation of Cx43 hemichannels by TNFα in HeLa cells stably overexpressing Cx43 and in the endothelial cell line EA.hy926
Stijn Verwaerde
Maarten De Smet
Tinneke Delvaeye
Alessio Lissoni
Peter Vandenabeele
Luc Leybaert
C3
Conferentie
2018
Cx43 hemichannel opening in ventricular cardiomyocytes necessitates simultaneous ryanodine receptor activation and elevation of intracellular Ca2+
Alessio Lissoni
Maarten De Smet
Paco Hulpiau
Tania Martins-Marques
Nan Wang
Henrique Girao
Luc Leybaert
C3
Conferentie
2018
Functional consequences of Cx43 hemichannels in adult cardiac myocytes
Luc Leybaert
Maarten De Smet
C3
Conferentie
2018
RyR2 regulates Cx43 hemichannel [Ca2+]i-dependent activation in cardiomyocytes
Alessio Lissoni
Maarten De Smet
Tania Martins-Marques
Nan Wang
Henrique Girao
Paco Hulpiau
Luc Leybaert
C3
Conferentie
2018
RyR2 regulates Cx43 hemichannel [Ca2+]i-dependent activation in cardiomyocytes
Alessio Lissoni
Maarten De Smet
Tania Martins-Marques
Herique Girao
Nan Wang
Paco Hulpiau
Luc Leybaert
C3
Conferentie
2018
RyR2 regulates Cx43 hemichannel [Ca2+]i-dependent activation in cardiomyocytes
Alessio Lissoni
Maarten De Smet
Tania Martins-Marques
Nan Wang
Henrique Girao
Paco Hulpiau
Luc Leybaert
C3
Conferentie
2018
2017
Activation, regulation and arrhythmogenic implications of Cx43 hemichannels in ventricular cardiomyocytes
Maarten De Smet
Alessio Lissoni
Nan Wang
Eef Dries
Karin Sipido
Luc Leybaert
C3
Conferentie
2017
Cx43 hemichannel opening in ventricular cardiomyocytes necessitates simultaneous ryanodine receptor activation and elevation of intracellular Ca2+
Alessio Lissoni
Maarten De Smet
Tânia Martins-Marques
Nan Wang
Henrique Girão
Luc Leybaert
C3
Conferentie
2017
Cx43 hemichannel opening in ventricular cardiomyocytes necessitates simultaneous ryanodine receptor activation and elevation of intracellular Ca2+, and is modulated by CaMKII and p38MAPK
Alessio Lissoni
Maarten De Smet
Nan Wang
Luc Leybaert
C3
Conferentie
2017
Cx43 hemichannel opening in ventricular cardiomyocytes necessitates simultaneous ryanodine receptor activation and elevation of intracellular Ca2+, and is modulated by CaMKII and p38MAPK
Alessio Lissoni
Maarten De Smet
Nan Wang
Luc Leybaert
C3
Conferentie
2017
Mitochondrial Cx43 hemichannels contribute to mitochondrial calcium entry and cell death in the heart
Ashish Kumar Gadicherla
Nan Wang
Marco Bulic
Esperanza Agullo-Pascual
Alessio Lissoni
Maarten De Smet
Mario Delmar
Geert Bultynck
Dmitri Krysko
Amadou Camara
et al.
A1
Artikel in een tijdschrift
in
BASIC RESEARCH IN CARDIOLOGY
2017
Modulation of Cx43 hemichannels by TNFα in HeLa cells overexpressing Cx43
Stijn Verwaerde
Maarten De Smet
Tinneke Delvaeye
Alessio Lissoni
Peter Vandenabeele
Dmitri Krysko
Luc Leybaert
C3
Conferentie
2017
Role of Cx43 hemichannels in ventricular arrhythmia associated with abnormal Ca2+ homeostasis
Maarten De Smet
Alessio Lissoni
Nan Wang
Luc Leybaert
C3
Conferentie
2017
Sex steroids in relation to cardiac structure and function in men
Maarten De Smet
Bruno Lapauw
Tine De Backer
A1
Artikel in een tijdschrift
in
ANDROLOGIA
2017
2016
Activation, regulation and arrhythmogenic implications of Cx43 hemichannels in ventricular cardiomyocytes
Maarten De Smet
Alessio Lissoni
Nan Wang
Luc Leybaert
C3
Conferentie
2016
Cx43 hemichannel opening in ventricular cardiomyocytes necessitates simultaneous ryanodine receptor activation and elevation of intracellular Ca2+, and is modulated by CaMKII
Alessio Lissoni
Maarten De Smet
Nan Wang
Luc Leybaert
C3
Conferentie
2016
Cx43 hemichannels in ventricular cardiomyocytes can be activated by an elevation of cytoplasmic Ca2+ through a CaM-dependent signaling cascade and are a potent contributor to cardiac arrhythmogenesis
Maarten De Smet
Alessio Lissoni
Nan Wang
Luc Leybaert
C3
Conferentie
2016
Cx43 hemichannels in ventricular cardiomyocytes can be activated by an elevation of cytoplasmic Ca2+ through a CaM-dependent signaling cascade and are a potent contributor to cardiac arrhythmogenesis
Maarten De Smet
Alessio Lissoni
Nan Wang
Luc Leybaert
C3
Conferentie
2016
Whole-cell patch clamp recordings of unitary connexin 43 hemichannel currents
Nan Wang
Alessio Lissoni
Maarten De Smet
Karin R Sipido
Luc Leybaert
Hoofdstuk in een boek
in
Gap junction channels and hemichannels
2016
2015
Cx43 hemichannels in ventricular cardiomyocytes can be activated by an elevation of cytoplasmic Ca2+ and are a potential arrhythmogenic substrate in the heart
Luc Leybaert
Maarten De Smet
C3
Conferentie
2015
2014
Een 75-jarige vrouw met inspanningsgebonden kortademigheid en desaturatie
Maarten De Smet
Eline Naert
Thomas Malfait
Guy Brusselle
Eric Derom
A2
Artikel in een tijdschrift
in
TIJDSCHRIFT VOOR GENEESKUNDE
2014
2013
Short-term changes in serum sex steroid levels and cardiac function in healthy young men
Maarten De Smet
Bruno Lapauw
Tine De Backer
Johannes Ruige
C3
Conferentie
2013
2012
Enhancing information extraction from clinical practice guidelines to improve the transparency and efficiency of Clinical Decision Support development
Maarten De Smet
Tine De Backer
Robert Vander Stichele
C3
Conferentie
2012