Research Explorer

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Researcher

Maaike Van Trimpont

Publications & Research Data

Awards & Distinctions

17 Results

2025

A human-like glutaminase-free asparaginase is highly efficacious in ASNS-low leukemia and solid cancer mouse xenograft models

Maaike Van TrimpontAmanda M. SchalkKenneth HofkensEvelien PeetersSara T'SasKatrien VandemeulebroeckeYing SuAshley De LoeraAlyssa GarciaHui Chen et al.

A1 Journal Article in CANCER LETTERS

CCR1 inhibition sensitizes multiple myeloma cells to glucocorticoid therapy

Bert LuyckxMaaike Van TrimpontFien DeclerckEleni StaessensAnnick VerheeSara T'SasSven EyckermanFritz OffnerPieter Van VlierbergheSteven Goossens et al.

A1 Journal Article in PHARMACOLOGICAL RESEARCH

Epigenetic rewiring of protein kinase signalling in T-cell acute lymphoblastic leukaemia

Claudina A. Pérez-NovoAmber DriesenMaaike Van TrimpontClaudia TheysEmilie LogiePieter Van VlierbergheWim Vanden Berghe

A2 Journal Article in KINASES AND PHOSPHATASES

Peptide hydrogels as slow-release formulations of protein therapeutics : case study of asparaginase-loaded hydrogels

Hue VuEvelien PeetersKenneth HofkensKatrien VandemeulebroeckeSara T'SasCharlotte MartinSteven BalletRichard HoogenboomSteven GoossensTim Lammens et al.

A1 Journal Article in BIOMATERIALS SCIENCE

2024

Ikaros loss enhances pre-leukemic thymocyte self-renewal and drives T-all in mice

Maaike Van TrimpontSara T'SasTim LammensPieter Van VlierbergheTim PietersSteven Goossens

2023

A novel mammalian L-asparaginase with no L-glutaminase activity is highly efficacious against T-cell acute lymphoblastic leukemia in vivo

Maaike Van TrimpontAmanda SchalkEvelien PeetersTim LammensSteven GoossensArnon LaviePieter Van Vlierberghe

A role for IKZF1 in pre-leukemic T-all?

Maaike Van TrimpontTim LammensSteven GoossensPieter Van Vlierberghe

Exploration of neuroblastoma xenograft models for the analysis of tumoral cell-free RNA in murine blood plasma

Jill DeleuHanne Van DroogenbroeckJasper AnckaertJilke De WildeKaat DurinckLiselot MusJustine NuytensMuhammad RishfiKathleen SchoofsFranki Speleman et al.

Exploration of neuroblastoma xenograft models for tumor extracellular RNA profiling in murine blood plasma

Jill DeleuHanne Van DroogenbroeckJasper AnckaertAnneleen DecockJilke De WildeKaat DurinckLiselot MusJustine NuytensMuhammad RishfiKathleen Schoofs et al.

A2 Journal Article in EXRNA

In vivo stabilization of a less toxic asparaginase variant leads to a durable antitumor response in acute leukemia

Maaike Van TrimpontAmanda M. SchalkYanti De VisserHien Anh NguyenLindy ReunesKatrien VandemeulebroeckeEvelien PeetersYing SuHyun LeePhilip L. Lorenzi et al.

A1 Journal Article in HAEMATOLOGICA

2022

A multi-omic, functional precision oncology method to identify responsive glioblastoma tumor cells at single cell resolution

Yanti De VisserDena PanovskaBasiel ColeLotte HermansAsier Antoranz MartinezPouya NazariMaaike Van TrimpontMarleen DerweduweAnnelies ClaeysSteven De Vleeschouwer et al.

Novel insights on the use of L-asparaginase as an efficient and safe anti-cancer therapy

Maaike Van TrimpontEvelien PeetersYanti De VisserAmanda M. SchalkVeerle MondelaersBarbara De MoerlooseArnon LavieTim LammensSteven GoossensPieter Van Vlierberghe

A1 Journal Article in CANCERS

Novel molecular insights and improved therapies in T-cell acute lymphoblastic leukemia

Maaike Van TrimpontPieter Van VlierbergheSteven Goossens

2021

Cell-penetrating Alphabody protein scaffolds for intracellular drug targeting

Erwin PannecouckeMaaike Van TrimpontJohan DesmetTim PietersLindy ReunesLisa DemoenMarnik VuylstekeStefan LoverixKaren VandenbrouckePhilippe Alard et al.

A1 Journal Article in SCIENCE ADVANCES

Cross-talk between GLI transcription factors and FOXC1 promotes T-cell acute lymphoblastic leukemia dissemination

Valeria ToselloDeborah BongiovanniJingjing LiuQingfei PanKoon-kiu YanValentina SaccomaniMaaike Van TrimpontMarco PizziMartina MazzoniAngelo Paolo Dei Tos et al.

A1 Journal Article in LEUKEMIA

Cyclin D2 overexpression drives B1a-derived MCL-like lymphoma in mice

Tim PietersSara T'SasStijn VanheeAndré Pedro Pinto De AlmeidaYasmine DriegeJuliette RoelsWouter Van LoockeWillem DaneelsMathijs BaensArnaud Marchand et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

The spleen as a sanctuary site for residual leukemic cells following ABT-199 monotherapy in ETP-ALL

Alessandra Di GrandeSofie PeirsPaul D. DonovanMaaike Van TrimpontJulie MorscioBéatrice LintermansLindy ReunesNiels VandammeSteven GoossensHien Anh Nguyen et al.

A1 Journal Article in BLOOD ADVANCES