Research Explorer

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Researcher

Lynda Grine

Awards & Distinctions

46 Results

2024

Exposure-response relationship of guselkumab and the potential of serum proteomics in identifying predictive biomarker candidates in psoriasis

Rani SoenenLisa SchotsZ. WangLaurentijn TillemanFilip Van NieuwerburghLynda GrineL. TemmermanT. HillaryA. StockmanE. Dreesen et al.

A1 Journal Article in JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Optimizing the use of biologics in psoriasis : role of therapeutic drug monitoring and serum biomarkers

Lisa SchotsJo LambertLynda GrineXavier Verhelst

2023

Therapeutic drug monitoring in psoriasis : from empiric dose adaptations to guided clinical decision making

Rani SoenenJo LambertPaul DeclerckLynda GrineDebby Thomas

2022

Dermatologists on the medical need for therapeutic drug monitoring of biologics in psoriasis : results of a structured survey

Lisa SchotsLynda GrineRani SoenenJo Lambert

A1 Journal Article in JOURNAL OF DERMATOLOGICAL TREATMENT

Image analysis systems to calculate the surface area of vitiligo lesions : a systematic review of measurement properties

Nanja van GeelImke SaeysJérôme Van CausenbroeckJolien DuponselleLynda GrineNele PauwelsNiels HilhorstSandrine HerbeletKhaled EzzedineReinhart Speeckaert

A1 Journal Article in PIGMENT CELL & MELANOMA RESEARCH

Patient-relevant outcomes in psoriasis : a systematic review

Niels HilhorstElfie DeprezNele PauwelsLynda GrineJo LambertIsabelle Hoorens

A1 Journal Article in JAMA DERMATOLOGY

Promising tools to facilitate the implementation of TDM of biologics in clinical practice

Rani SoenenChristophe StoveAlessio CapobiancoHanne De SchutterMarie DobbelaereTahmina MahjorMerel FollensJo LambertLynda Grine

A1 Journal Article in JOURNAL OF CLINICAL MEDICINE

The effects of Modified Intermittent Fasting in Psoriasis (MANGO) : preliminary results of a pilot crossover study

Lynda GrineNiels HilhorstFien StrobbeRaquel Van Den EyndeElien GeeritsEmma CoppenolleNathalie MichelsSouheila AbbeddouStefaan De HenauwJo Lambert

The effects of Modified Intermittent Fasting in Psoriasis (MANGO) trial : a two-arm pilot randomized controlled open cross-over study

Lynda GrineNiels HilhorstNathalie MichelsSouheila AbbedouStefaan De HenauwJo Lambert

A2 Journal Article in JMIR RESEARCH PROTOCOLS

Therapeutic drug monitoring in dermatology : the way towards dose optimization of secukinumab in chronic plaque psoriasis

Rani SoenenZhigang WangLynda GrineErwin DreesenLisa SchotsEls BrouwersPaul DeclerckDebby ThomasJo Lambert

A1 Journal Article in CLINICAL AND EXPERIMENTAL DERMATOLOGY

2021

Dose reduction of the new generation biologics (IL-17 and IL-23 inhibitors) in psoriasis : study protocol for an international, pragmatic, multicenter, randomized, controlled, non-inferiority study : the BeNeBio study

Lara S. van der SchootJuul M. P. A. van den ReekLynda GrineLisa SchotsWietske KievitJo LambertElke M. G. J. de Jong

A1 Journal Article in TRIALS

Effectiveness and tolerability of guselkumab in patients with psoriasis : a longitudinal Belgian retrospective multicenter study

Pierre-Dominique GhislainValérie FaillaJo LambertRani SoenenLynda GrineJulio TannousFrançoise GuiotFabienne WillaertHugues FierensMark Vandaele et al.

A2 Journal Article in JAAD INTERNATIONAL

Gut-skin axis : current knowledge of the interrelationship between microbial dysbiosis and skin conditions

Britta De PessemierLynda GrineMelanie DebaereAglaya MaesBernhard PaetzoldChris Callewaert

A1 Journal Article in MICROORGANISMS

Interim results of the MANGO trial : modified intermittent fasting in psoriasis

Lynda GrineNiels HilhorstNathalie MichelsSouheila AbbeddouStefaan De HenauwJo Lambert

The implementation of a structured specialized consultation for psoriasis management

Jo LambertANA ALVES DE MEDEIROSAstrid Van ReemptsKim Van LangenhoveJudith RosseyElfie DeprezLucia Van PouckeLynda Grine

A1 Journal Article in ACTA CLINICA BELGICA

Validation of a Patient Global Assessment for extent, severity and impact to define the severity strata for the Self Assessment Vitiligo Extent Score (SA-VES)

Nanja van GeelS. E. UitentuisM. ZuidgeestA. WolkerstorferM. W. BekkenkC. MoockC. Van GoethemE. VerlaecktC. SmetLynda Grine et al.

A1 Journal Article in JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

2020

A Belgian consensus on the definition of a treat‐to‐target outcome set in psoriasis management

Lynda GrineMichel de la BrassinnePierre‐Dominique GhislainTom HillaryJulien LambertSiegfried SegaertFabienne WillaertJo LambertFarida BenhadouChantal Bonardeaux et al.

A1 Journal Article in JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Comparison of personality traits among patients with psoriasis, atopic dermatitis, and stress: a pilot study

Lynda GrineGiulia TochtermannHilde LapeereNele MaesGünther F. L. HofbauerMyriam VervaetJo Lambert

A1 Journal Article in DERMATOLOGY

Development and validation of immunoassays for monitoring of guselkumab and anti-guselkumab antibodies in patients with moderate-to-severe psoriasis

Nathalie Van den BergheAurélie TruffotMiet PeetersGriet CompernolleEls BrouwersRani SoenenLynda GrineAnn GilsMaya Imbrechts

A1 Journal Article in JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Improving patient involvement in the lifecycle of medicines : insights from the EUPATI BE survey

Lynda GrineRosanne JanssensEline van OverbeekeDanielle DerijckeMitchell SilvaBelinda DelysIsabelle DusartVeerle AertsenMagali Mertens de WilmarsJoanna Robaczewska et al.

A1 Journal Article in FRONTIERS IN MEDICINE

Standardizing serial photography for assessing and monitoring vitiligo : a core set of international recommendations for essential clinical and technical specifications

Nanja van GeelIltefat HamzaviIndermeet KohliAlbert WolkerstorferHenry W. LimJung Min BaeHarvey LuiJohn E. HarrisAmit G. PandyaSteven Thng Tien Guan et al.

A1 Journal Article in JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

2019

Clinical visible signs of disease activity in vitiligo : a systematic review and meta‐analysis

Nanja van GeelLynda GrinePauline de WispelaereD MertensCAC PrinsenReinhart Speeckaert

A1 Journal Article in JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Defining a minimal effective serum trough concentration of secukinumab in psoriasis : a step toward personalized therapy

Rani SoenenEvelyn MeulewaeterLynda GrineNathalie Van den BergheEls BrouwersReinhart SpeeckaertSven LanssensLinda TemmermanJo LambertAnn Gils

A1 Journal Article in JOURNAL OF INVESTIGATIVE DERMATOLOGY

Developing a therapeutic window for secukinumab in psoriasis : a step towards personalized therapy

Rani SoenenEvelyn MeulewaeterLynda GrineLinda TemmermanSven LanssensEls BrouwersNathalie Van den BergheReinhart SpeeckaertJo LambertAnn Gils

Reference method for digital surface measurement of target lesions in vitiligo : a comparative analysis

Nanja van GeelD VandendriesscheE VandersichelS De SchepperLynda GrineL MertensV VandaeleF SpoeldersM BekkenkA Wolkerstorfer et al.

A1 Journal Article in BRITISH JOURNAL OF DERMATOLOGY

Therapeutic patient education and self‐management support for patients with psoriasis : a systematic review

Corinna DresslerJo LambertLynda GrinePaul GaldasCarle PaulMiriam ZidaneAlexander Nast

A2 Journal Article in JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT

Therapeutische Patientenschulungsprogramme und Unterstützung beim Selbstmanagement für Patienten mit Psoriasis : eine systematische Übersicht

Corinna DresslerJo LambertLynda GrinePaul GaldasCarle PaulMiriam ZidaneAlexander Nast

A1 Journal Article in JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT

2018

Developing a therapeutic window for secukinumab in psoriasis : a step towards personalized therapy

Rani SoenenEvelyn MeulewaeterLynda GrineNathalie Van den BergheEls BrouwersReinhart SpeeckaertSven LanssensLinda TemmermanJo LambertAnn Gils

Managing psoriasis anno 2018 : a route towards personalising treatment

Ana Alves de MedeirosJo LambertLynda Grine

Targeting the IL-23/IL-17 pathway in psoriasis : the search for the good, the bad and the ugly

Sofie MylleLynda GrineReinhart SpeeckaertJo LambertNanja van Geel

A1 Journal Article in AMERICAN JOURNAL OF CLINICAL DERMATOLOGY

Towards the development of a RNAi-based topical treatment for psoriasis : proof-of-concept in a 3D psoriasis skin model

Eline DesmetMireille Van GeleLynda GrineKatrien RemautJo Lambert

A1 Journal Article in EXPERIMENTAL DERMATOLOGY

2017

Dienst Dermatologie UZ Gent wordt beloond voor inzet in de zorg voor psoriasis

Lynda GrineAna Alves de MedeirosNele MaesElfie DeprezLucia Van PouckeJo Lambert

Laat wat van je horen

Lynda GrineJo Lambert

2016

Analysis of telomere length as predictive marker in psoriasis for comorbidities

Emma CoussensLynda GrineJESSICA BOSTOENHerman MielantsJo Lambert

A1 Journal Article in EXPERIMENTAL DERMATOLOGY

Comment on 'Tumour necrosis factor-α plays a significant role in the Aldara-induced skin inflammation in mice'

Lynda GrineClaude LibertRoosmarijn Vandenbroucke

A1 Journal Article in BRITISH JOURNAL OF DERMATOLOGY

Global survey into the use of therapeutic patient education during psoriasis management

Lynda GrineJo LambertC PaulA Nast

Je hebt psoriasis... maar ken je psoriasis?

Lynda GrineJo Lambert

Psoriasis : burning down the host

Lynda GrineJo Lambert

Editorial material

The many faces of interleukin-17 in inflammatory skin diseases

Reinhart SpeeckaertJo LambertLynda GrineMireille Van GeleSofie De SchepperNanja van Geel

A1 Journal Article in BRITISH JOURNAL OF DERMATOLOGY

Topical imiquimod yields systemic effects due to unintended oral uptake

Lynda GrineSophie SteelandSara Van RyckeghemMarlies BallegeerStefan LienenklausSiegfried WeissNiek SandersRoosmarijn VandenbrouckeClaude Libert

A1 Journal Article in SCIENTIFIC REPORTS

2015

An inflammatory triangle in psoriasis: TNF, type I IFNs and IL-17

Lynda GrineLien DejagerClaude LibertRoosmarijn Vandenbroucke

A1 Journal Article in CYTOKINE & GROWTH FACTOR REVIEWS

Dual inhibition of TNFR1 and IFNAR1 in imiquimod-induced psoriasiform skin inflammation in mice

Lynda GrineLien DejagerClaude LibertRoosmarijn Vandenbroucke

A1 Journal Article in JOURNAL OF IMMUNOLOGY

TNFR1-induced lethal inflammation is mediated by goblet and Paneth cell dysfunction

Filip Van HauwermeirenRoosmarijn VandenbrouckeLynda GrineSofie LodensElien Van WonterghemRiet De RyckeN De GeestB HassanClaude Libert

A1 Journal Article in MUCOSAL IMMUNOLOGY

microRNAs in psoriasis: leaders or followers?

Jo LambertLynda GrineMireille Van Gele

Editorial material

2014

Antisense oligonucleotides against TNFR1 prevent toxicity of TNF/IFNγ treatment in mouse tumor models

Filip Van HauwermeirenRoosmarijn VandenbrouckeLynda GrineLeen PuimègeElien Van WonterghemHong ZhangClaude Libert

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

Study of the role of type I interferons in TNF-mediated inflammation

Lynda GrineClaude LibertRoosmarijn Vandenbroucke