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Onderzoeker
Linos Vandekerckhove
Profiel
Projecten
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Prijzen & Erkenningen
311
Resultaten
2024
Case series of kaposi sarcoma in HIV-negative men who have sex with men : potential therapeutic approaches
Niels Hilhorst
Barbara Devocht
Evelien Verhaeghe
Lore Lapeire
Linos Vandekerckhove
Soetkin Desmet
Marie-Angélique De Scheerder
Lieve Brochez
A2
Artikel in een tijdschrift
in
JOURNAL OF DERMATOLOGY RESEARCH AND THERAPY
2024
Development of a novel assay to characterize the HIV-1 reservoir using long-read sequencing
Laurens Lambrechts
Linos Vandekerckhove
Wim Van Criekinge
Proefschrift
2024
Development of human innate immune responses in a humanized mouse model expressing four human myelopoiesis transgenes
Hannah Stocks
Elisabeth De Leeuw
Bart Lambrecht
Linos Vandekerckhove
Geert van Loo
Andy Wullaert
U
Artikel in een tijdschrift
in
FRONTIERS IN IMMUNOLOGY
2024
Host lncRNAs and their interplay with the HIV-1 infection cycle
Willem van Snippenberg
Pieter Mestdagh
Linos Vandekerckhove
Wim Trypsteen
Proefschrift
2024
Longitudinal patterns of inflammatory mediators after acute HIV infection correlate to intact and total reservoir
Jozefien De Clercq
Marie-Angélique De Scheerder
Virginie Mortier
Chris Verhofstede
Stefaan J. Vandecasteele
Sabine D. Allard
Coca Necsoi
Stephane De Wit
Sarah Gerlo
Linos Vandekerckhove
A1
Artikel in een tijdschrift
in
FRONTIERS IN IMMUNOLOGY
2024
Mapping bacterial extracellular vesicle research : insights, best practices and knowledge gaps
Nele De Langhe
Sofie Van Dorpe
Niké Guilbert
Amélie Vander Cruyssen
Quentin Roux
Sarah Deville
Sandor Dedeyne
Philippe Tummers
Hannelore Denys
Linos Vandekerckhove
et al.
A1
Artikel in een tijdschrift
in
NATURE COMMUNICATIONS
2024
Spiroplasma infection as a cause of severe congenital keratouveitis, cataract and glaucoma
Helena Van Haecke
Dimitri Roels
Fanny Nerinckx
Heidi Schaballie
Petra Schelstraete
Linos Vandekerckhove
Jolien Van Cleemput
Wim Van Den Broeck
Liesbeth Couck
Hannelore Hamerlinck
et al.
A1
Artikel in een tijdschrift
in
BMC OPHTHALMOLOGY
2024
2023
A complement atlas identifies interleukin-6-dependent alternative pathway dysregulation as a key druggable feature of COVID-19
Karel Van Damme
Levi Hoste
Jozefien Declercq
Elisabeth De Leeuw
Bastiaan Maes
Liesbet Martens
Roos Colman
Robin Browaeys
Cédric Bosteels
Stijn Verwaerde
et al.
A1
Artikel in een tijdschrift
in
SCIENCE TRANSLATIONAL MEDICINE
2023
Bictegravir/emtricitabine/tenofovir alafenamide in older individuals with HIV : results of a 96‐week, phase 3b, open‐label, switch trial in virologically suppressed people ≥65 years of age
Franco Maggiolo
Giuliano Rizzardini
Jean‐Michel Molina
Federico Pulido
Stephane De Wit
Linos Vandekerckhove
Juan Berenguer
Michelle L. D'Antoni
Christiana Blair
Susan K. Chuck
et al.
A1
Artikel in een tijdschrift
in
HIV MEDICINE
2023
Efficacy, durability, and tolerability of bictegravir/emtricitabine/tenofovir alafenamide for the treatment of HIV in a real‐world setting in Belgium
Rakan Nasreddine
Eric Florence
Jean Cyr Yombi
Sophie Henrard
Gilles Darcis
Jens Van Praet
Linos Vandekerckhove
Sabine D. Allard
Rémy Demeester
Peter Messiaen
et al.
A1
Artikel in een tijdschrift
in
HIV MEDICINE
2023
Evaluating lncRNA expression patterns during HIV-1 treatment interruption
Tinus Schynkel
Willem van Snippenberg
Clarissa Van Hecke
Linos Vandekerckhove
Wim Trypsteen
A1
Artikel in een tijdschrift
in
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2023
Exploring HIV-1 protein : host RNA interactions during HIV-1 infection
Tinus Schynkel
Linos Vandekerckhove
Wim Trypsteen
Pieter Mestdagh
Proefschrift
2023
HIV-PULSE : a long-read sequencing assay for high-throughput near full-length HIV-1 proviral genome characterization
Laurens Lambrechts
Noah Bonine
Rita Verstraeten
Marion Pardons
Ytse Noppe
Sofie Rutsaert
Filip Van Nieuwerburgh
Wim Van Criekinge
Basiel Cole
Linos Vandekerckhove
Preprint
2023
HIV-PULSE : a long-read sequencing assay for high-throughput near full-length HIV-1 proviral genome characterization
Laurens Lambrechts
Noah Bonine
Rita Verstraeten
Marion Pardons
Ytse Noppe
Sofie Rutsaert
Filip Van Nieuwerburgh
Wim Van Criekinge
Basiel Cole
Linos Vandekerckhove
A1
Artikel in een tijdschrift
in
NUCLEIC ACIDS RESEARCH
2023
In-depth assessment of the HIV-1 viral reservoir in early treated individuals
Tine Struyve
Marion Pardons
Liesbet Termote
Jozefien De Clercq
Laurens Lambrechts
Jerel Vega
Daniel Boden
Mathias Lichterfeld
Sofie Rutsaert
Linos Vandekerckhove
C3
Conferentie
2023
In-depth virological and immunological characterization of HIV-1 cure after CCR5 Delta 32/Delta 32 allogeneic hematopoietic stem cell transplantation
Bjoern-Erik Ole Jensen
Elena Knops
Leon Cords
Nadine Luebke
Maria Salgado
Kathleen Busman-Sahay
Jacob D. D. Estes
Laura E. P. Huyveneers
Federico Perdomo-Celis
Melanie Wittner
et al.
A1
Artikel in een tijdschrift
in
NATURE MEDICINE
2023
Influence of UGT1A1 and SLC22A6 polymorphisms on the population pharmacokinetics and pharmacodynamics of raltegravir in HIV-infected adults : a NEAT001/ANRS143 sub-study
Rohan Gurjar
Laura Dickinson
Daniel Carr
Wolfgang Stohr
Stefano Bonora
Andrew Owen
Antonio D'Avolio
Adam Cursley
Nathalie De Castro
Gerd Fatkenheuer
et al.
A1
Artikel in een tijdschrift
in
PHARMACOGENOMICS JOURNAL
2023
Linking inducible HIV-1 reservoir to rebound after treatment interruption
Laurens Lambrechts
Ytse Noppe
Marion Pardons
Basiel Cole
Sofie Rutsaert
Stéphane De Wit
Guido Vanham
Eric Florence
Linos Vandekerckhove
C3
Conferentie
2023
No significant association between 25-OH vitamin D status and SARS-VoV-2 antibody response after COVID-19 vaccination in nursing home residents and staff
Eline Meyers
Evelien De Smet
Hanne Vercruysse
Steven Callens
Elizaveta Padalko
Stefan Heytens
Linos Vandekerckhove
Piet Cools
Wojciech Witkowski
A1
Artikel in een tijdschrift
in
VACCINES
2023
Optimization of a long-read sequencing assay for near full-length HIV-1 proviral genome characterization
Sofie De Braekeleer
Laurens Lambrechts
Sofie Rutsaert
Linos Vandekerckhove
C3
Conferentie
2023
Optimization of a long-read sequencing assay for near full-length HIV-1 proviral genome characterization to enhance read accuracy
Sofie De Braekeleer
Laurens Lambrechts
Sofie Rutsaert
Linos Vandekerckhove
C3
Conferentie
2023
Potent latency reversal by Tat RNA-containing nanoparticle enables multi-omic analysis of the HIV-1 reservoir
Marion Pardons
Basiel Cole
Laurens Lambrechts
Willem van Snippenberg
Sofie Rutsaert
Ytse Noppe
Nele De Langhe
Annemieke Dhondt
Jerel Vega
Filmon Eyassu
et al.
A1
Artikel in een tijdschrift
in
NATURE COMMUNICATIONS
2023
Rethinking IL-1 antagonism in respiratory viral infections : a role for IL-1 signaling in the development of antiviral T cell immunity
Bram Van Den Eeckhout
Marlies Ballegeer
Jozefien De Clercq
Elianne Burg
Xavier Saelens
Linos Vandekerckhove
Sarah Gerlo
A1
Artikel in een tijdschrift
in
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2023
Sniffing out safety : canine detection and identification of SARS-CoV-2 infection from armpit sweat
Chris Callewaert
Maria Pezavant
Rony Vandaele
Bart Meeus
Ellen Vankrunkelsven
Phaedra Van Goethem
Alain Plumacker
Benoit Misset
Gilles Darcis
Sonia Piret
et al.
A1
Artikel in een tijdschrift
in
FRONTIERS IN MEDICINE
2023
Targeted plasma proteomics identifies MICA and IL1R1 proteins associated with HIV-1 reservoir size
Marc J. T. Blaauw
Jessica Cristina dos Santos
Nadira Vadaq
Wim Trypsteen
Wouter van der Heijden
Albert Groenendijk
Zhenhua Zhang
Yang Li
Quirijn de Mast
Mihai G. Netea
et al.
A1
Artikel in een tijdschrift
in
ISCIENCE
2023
The Rainbow 5-plex digital PCR assay improves quantification of the viral reservoir resulting in a better understanding of the HIV-1 proviral landscape
Mareva Delporte
Laurens Lambrechts
Marion Pardons
Sofie De Braekeleer
Evy Blomme
Sofie Rutsaert
Wim Trypsteen
Linos Vandekerckhove
C3
Conferentie
2023
Unraveling ongoing inflammation after early ART by in-depth analysis of lymph nodes
Jozefien De Clercq
Kathleen Busman-Sahay
Laurens Lambrechts
Sofie Rutsaert
Sol Taylor-Brill
Stephen Bondoc
Marie-Angélique De Scheerder
Jacob Estes
Sarah Gerlo
Linos Vandekerckhove
C3
Conferentie
2023
2022
A dual-antigen self-amplifying RNA SARS-CoV-2 vaccine induces potent humoral and cellular immune responses and protects against SARS-CoV-2 variants through T cell-mediated immunity
Séan Mc Cafferty
A. K. M. Ashiqul Haque
Aster Vandierendonck
Brian Weidensee
Magalie Plovyt
Magdalena Stuchlikova
Nathalie François
Sophie Valembois
Leo Heyndrickx
Johan Michiels
et al.
A1
Artikel in een tijdschrift
in
MOLECULAR THERAPY
2022
A night with professor Linos : interview of approach to multidisciplinary HIV research and other applications
Tine Vanhaverbeke
Nele De Langhe
Eva Degraeuwe
Eline Hermans
Laurens Van Camp
Johan Vande Walle
Mirko Petrovic
Linos Vandekerckhove
Andere
2022
Association of COVID-19 mortality with serum selenium, zinc and copper : six observational studies across Europe
Kamil Demircan
Thilo Samson Chillon
Tommy Bracken
Ilaria Bulgarelli
Irene Campi
Gijs Du Laing
Samira Fafi-Kremer
Laura Fugazzola
Alejandro Abner Garcia
Raban Heller
et al.
A1
Artikel in een tijdschrift
in
FRONTIERS IN IMMUNOLOGY
2022
Benefits of antiretroviral therapy initiation during acute HIV infection
Jozefien De Clercq
Sofie Rutsaert
Marie-Angélique De Scheerder
Chris Verhofstede
Steven Callens
Linos Vandekerckhove
A1
Artikel in een tijdschrift
in
ACTA CLINICA BELGICA
2022
COVID‐19 vaccination with BNT162b2 and ChAdOx1 vaccines has the potential to induce nasal neutralizing antibodies
Jozefien Declercq
Els Tobback
Stijn Vanhee
Natalie De Ruyck
Sarah Gerlo
Philippe Gevaert
Linos Vandekerckhove
A1
Artikel in een tijdschrift
in
ALLERGY
2022
Characterization of the HIV-1 viral reservoir in subtype B early treated individuals
Tine Struyve
Marion Pardons
Liesbet Termote
Jozefien De Clercq
Laurens Lambrechts
Jerel Vega
Daniel Boden
Mathias Lichterfeld
Sofie Rutsaert
Linos Vandekerckhove
C3
Conferentie
2022
Clonal hematopoiesis is associated with low CD4 nadir and increased residual HIV transcriptional activity in virally suppressed individuals with HIV
Wouter A. van der Heijden
Rosanne C. van Deuren
Lisa van de Wijer
Inge C. L. van den Munckhof
Marloes Steehouwer
Niels P. Riksen
Mihai G. Netea
Quirijn de Mast
Linos Vandekerckhove
Richarda M. de Voer
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF INFECTIOUS DISEASES
2022
Diagnostic performance of the SARS-CoV-2 S1RBD IgG ELISA (immunodiagnostics) for the quantitative detection of SARS-CoV-2 antibodies on dried blood spots
Eline Meyers
Anja Coen
An De Sutter
Elizaveta Padalko
Steven Callens
Linos Vandekerckhove
Wojciech Witkowski
Stefan Heytens
Piet Cools
A1
Artikel in een tijdschrift
in
JOURNAL OF CLINICAL VIROLOGY
2022
Distinct immune profiles of HIV‐infected subjects are linked to specific lipid mediator signature
Magdalena Sips
Sarah Gerlo
Laura De Clercq
Esteban A. Gomez
Romain A. Colas
Jesmond Dalli
Linos Vandekerckhove
A1
Artikel in een tijdschrift
in
IMMUNITY INFLAMMATION AND DISEASE
2022
Extensive characterization of HIV-1 reservoirs reveals links to plasma viremia before and during analytical treatment interruption
Basiel Cole
Laurens Lambrechts
Zoe Boyer
Ytse Noppe
Marie-Angélique De Scheerder
John-Sebastian Eden
Bram Vrancken
Timothy E. Schlub
Sherry McLaughlin
Lisa M. Frenkel
et al.
A1
Artikel in een tijdschrift
in
CELL REPORTS
2022
HCV reinfection after HCV therapy among HIV/HCV-coinfected individuals in Europe
Sarah Amele
Anastasia Karachalia Sandri
Alison Rodger
Linos Vandekerckhove
Thomas Benfield
Ana Milinkovic
Claudine Duvivier
Hans-Jurgen Stellbrink
Helen Sambatakou
Nikoloz Chkhartishvili
et al.
A1
Artikel in een tijdschrift
in
HIV MEDICINE
2022
Humoral and cellular responses to COVID-19 vaccination indicate the need for post-vaccination testing in frail population
Wojciech Witkowski
Sarah Gerlo
Evelien De Smet
Magdalena Wejda
Delphine Acar
Steven Callens
Stefan Heytens
Elizaveta Padalko
Hannelore Vercruysse
Piet Cools
et al.
A1
Artikel in een tijdschrift
in
VACCINES
2022
Impact of switch towards 3TC/dolutegravir on the intact and total viral reservoir in the Rumba study
Evy Blomme
Wim Trypsteen
Mareva Delporte
C. Muccini
E. De Smet
Sophie Degroote
Els Tobback
Sophie Vanherrewege
E. Caluwe
Marie-Angélique De Scheerder
et al.
C3
Conferentie
2022
Long-read sequencing assay allows accurate characterization of the HIV-1 reservoir
Laurens Lambrechts
Rita Verstraeten
Noah Bonine
Ytse Noppe
Sofie Rutsaert
Marion Pardons
Basiel Cole
Linos Vandekerckhove
C3
Conferentie
2022
Long-read sequencing assay allows accurate characterization of the HIV-1 reservoir
Laurens Lambrechts
Rita Verstraeten
Noah Bonine
Ytse Noppe
Sofie Rutsaert
Marion Pardons
Basiel Cole
Linos Vandekerckhove
C3
Conferentie
2022
Long-read sequencing assay allows accurate characterization of the HIV-1 reservoir
Laurens Lambrechts
Rita Verstraeten
Noah Bonine
Ytse Noppe
Marion Pardons
Basiel Cole
Linos Vandekerckhove
C3
Conferentie
2022
Loss of GM-CSF-dependent instruction of alveolar macrophages in COVID-19 provides a rationale for inhaled GM-CSF treatment
Cédric Bosteels
Karel Van Damme
Elisabeth De Leeuw
Jozefien Declercq
Bastiaan Maes
Victor Bosteels
Levi Hoste
Leslie Naesens
Nincy Debeuf
Julie Deckers
et al.
A1
Artikel in een tijdschrift
in
CELL REPORTS MEDICINE
2022
Monkeypox virus infection in humans across 16 countries : April-June 2022
John P. Thornhill
Sapha Barkati
Sharon Walmsley
Juergen Rockstroh
Andrea Antinori
Luke B. Harrison
Romain Palich
Achyuta Nori
Iain Reeves
Maximillian S. Habibi
et al.
A1
Artikel in een tijdschrift
in
LANCET NEUROLOGY
2022
Patient-reported outcomes among people living with HIV on single- versus multi-tablet regimens : data from a real-life setting
Sophie Degroote
Linos Vandekerckhove
Dirk Vogelaers
Charlotte Vanden Bulcke
A1
Artikel in een tijdschrift
in
PLOS ONE
2022
People with HIV have higher percentages of circulating CCR5+CD8+T cells and lower percentages of CCR5+regulatory T cells
Louise E. van Eekeren
Vasiliki Matzaraki
Zhenhua Zhang
Lisa van de Wijer
Marc J. T. Blaauw
Marien I. de Jonge
Linos Vandekerckhove
Wim Trypsteen
Leo A. B. Joosten
Mihai G. Netea
et al.
A1
Artikel in een tijdschrift
in
SCIENTIFIC REPORTS
2022
Qualitative plasma viral load determination as a tool for screening of viral reservoir size in PWH
Thessa Laeremans
Sigrid D'haese
Jonathan Aernout
Kurt Barbe
Pieter Pannus
Sofie Rutsaert
Ellen Vancutsem
Guido Vanham
Coca Necsoi
Ward De Spiegelaere
et al.
A1
Artikel in een tijdschrift
in
AIDS
2022
Triplex digital PCR assays for the quantification of intact proviral HIV-1 DNA
Willem van Snippenberg
David Gleerup
Sofie Rutsaert
Linos Vandekerckhove
Ward De Spiegelaere
Wim Trypsteen
A1
Artikel in een tijdschrift
in
METHODS
2022
Understanding changes in metabolic parameters switching to 2DR or 3DR integrase strand inhibitors (InSTIs)
Sophie Degroote
Sophie Vanherrewege
Els Tobback
E. Caluwe
Lara Vincke
Evy Blomme
Linos Vandekerckhove
Marie-Angélique De Scheerder
C3
Conferentie
2022
Unraveling persistent inflammation after very early ART through in-depth analysis of lymph nodes
Jozefien De Clercq
Kathleen Busman-Sahay
Laurens Lambrechts
Sofie Rutsaert
Stephen Bondoc
Sol Taylor-Brill
Marie-Angélique De Scheerder
Jacob Estes
Sarah Gerlo
Linos Vandekerckhove
C3
Conferentie
2022
2021
A rare but devastating cause of twin loss in a near-term pregnancy highlighting the features of severe SARS-CoV-2 placentitis
Sasha Libbrecht
Jolien Van Cleemput
Linos Vandekerckhove
Sofie Colman
Elizaveta Padalko
Bruno Verhasselt
Koen Van de Vijver
Amélie Dendooven
Isabelle Dehaene
Jo Van Dorpe
Redactioneel materiaal
2021
Bictegravir/emtricitabine/tenofovir alafenamide in virologically suppressed people with HIV aged ≥ 65 years : week 48 results of a phase 3b, open-label trial
Franco Maggiolo
Giuliano Rizzardini
Jean-Michel Molina
Federico Pulido
Stephane De Wit
Linos Vandekerckhove
Juan Berenguer
Michelle L. D’Antoni
Christiana Blair
Susan K. Chuck
et al.
A1
Artikel in een tijdschrift
in
INFECTIOUS DISEASES AND THERAPY
2021
Chronic HIV infection induces transcriptional and functional reprogramming of innate immune cells
Wouter A. van der Heijden
Lisa Van de Wijer
Farid Keramati
Wim Trypsteen
Sofie Rutsaert
Rob ter Horst
Martin Jaeger
Hans J.P.M. Koenen
Hendrik G. Stunnenberg
Irma Joosten
et al.
A1
Artikel in een tijdschrift
in
JCI INSIGHT
2021
Clinical characteristics and outcomes of COVID‐19 in people living with HIV in Belgium : a multicenter, retrospective cohort
Rakan Nasreddine
Eric Florence
Michel Moutschen
Jean‐Cyr Yombi
Jean‐Christophe Goffard
Inge Derdelinckx
Patrick Lacor
Linos Vandekerckhove
Peter Messiaen
Stefaan Vandecasteele
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF MEDICAL VIROLOGY
2021
Course and survival of COVID-19 patients with comorbidities in relation to the trace element status at hospital admission
Gijs Du Laing
Mirko Petrovic
Carl Lachat
Marthe De Boevre
Georg Klingenberg
Qian Sun
Sarah De Saeger
Jozefien De Clercq
Louis Ide
Linos Vandekerckhove
et al.
A1
Artikel in een tijdschrift
in
NUTRIENTS
2021
Cytokine and chemokine dynamics in acute HIV infection and the impact of early ART initiation
Jozefien De Clercq
Grégoire Thomas
Sarah Gerlo
Linos Vandekerckhove
C3
Conferentie
2021
Cytotoxic CD8+ T cells expressing CXCR5 are detectable in HIV-1 elite controllers after prolonged in vitro peptide stimulation
Philipp Adams
Gilles Iserentant
Jean-Yves Servais
Linos Vandekerckhove
Guido Vanham
Carole Seguin-Devaux
[missing] the PhenoCure Study Group
A1
Artikel in een tijdschrift
in
FRONTIERS IN IMMUNOLOGY
2021
Development of novel assays to characterize the size and dynamics of the HIV-1 viral reservoir
Basiel Cole
Linos Vandekerckhove
Marion Pardons
Proefschrift
2021
Diagnosing COVID-19 : towards a feasible COVID-19 rule-out protocol
Jozefien De Clercq
Thomas Malfait
Simon Malfait
Jerina Boelens
Liselotte Coorevits
Elizaveta Padalko
Stien Vandendriessche
Bruno Verhasselt
Lieve Morbée
Fré Bauters
et al.
A1
Artikel in een tijdschrift
in
ACTA CLINICA BELGICA
2021
Effect of anti-interleukin drugs in patients with COVID-19 and signs of cytokine release syndrome (COV-AID) : a factorial, randomised, controlled trial
Jozefien Declercq
Karel Van Damme
Elisabeth De Leeuw
Bastiaan Maes
Cédric Bosteels
Simon Tavernier
Stefanie De Buyser
Roos Colman
Maya Hites
Gil Verschelden
et al.
A1
Artikel in een tijdschrift
in
LANCET RESPIRATORY MEDICINE
2021
HIV cure research in the time of COVID-19 : antiretroviral therapy treatment interruption trials : a discussion paper
S. Fidler
S. Lewin
S. Deeks
O. S. Sogaard
Linos Vandekerckhove
S. Collins
D. Kelly
J. Singh
M. Caskey
J. Frater
Redactioneel materiaal
2021
Human immunotypes impose selection on viral genotypes through viral epitope specificity
Migle Gabrielaite
Marc Bennedbaek
Adrian G. Zucco
Christina Ekenberg
Daniel D. Murray
Virginia L. Kan
Giota Touloumi
Linos Vandekerckhove
Dan Turner
James Neaton
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF INFECTIOUS DISEASES
2021
IRF7 and RNH1 are modifying factors of HIV-1 reservoirs : a genome-wide association analysis
Zhenhua Zhang
Wim Trypsteen
Marc Blaauw
Xiaojing Chu
Sofie Rutsaert
Linos Vandekerckhove
Wouter van der Heijden
Jessica Cristina Dos Santos
Cheng-Jian Xu
Morris A. Swertz
et al.
A1
Artikel in een tijdschrift
in
BMC MEDICINE
2021
In-depth characterization of HIV-1 reservoirs reveals links to viral rebound during treatment interruption
Basiel Cole
Laurens Lambrechts
Zoe Boyer
Ytse Noppe
Marie-Angélique De Scheerder
John-Sebastian Eden
Bram Vrancken
Timothy Schlub
Sherry McLaughlin
Lisa M. Frenkel
et al.
Preprint
2021
In-depth single-cell analysis of translation-competent HIV-1 reservoirs identifies cellular sources of plasma viremia
Basiel Cole
Laurens Lambrechts
Pierre Gantner
Ytse Noppe
Noah Bonine
Wojciech Witkowski
Lennie Chen
Sarah Palmer
James I. Mullins
Nicolas Chomont
et al.
A1
Artikel in een tijdschrift
in
NATURE COMMUNICATIONS
2021
In-depth single-cell analysis of translation-competent HIV-1 reservoirs identifies cellular sources of residual viremia and rebound viruses
Basiel Cole
Laurens Lambrechts
Pierre Gantner
Ytse Noppe
Noah Bonine
Lennie Chen
Sarah Palmer
James Mullins
Nicolas Chomont
Marion Pardons
et al.
C3
Conferentie
2021
Launching a multidisciplinary European collaboration towards a cure for HIV : the EU2Cure Consortium
C. Rokx
H. A. B. Prins
Linos Vandekerckhove
S. J. Fidler
J. Frater
M. Bracchi
O. S. Sogaard
M. Tolstrop
T. A. Rasmussen
M. Salgado
et al.
Redactioneel materiaal
2021
Measuring proviral HIV-1 DNA : hurdles and improvements to an assay monitoring integration events utilising human alu repeat sequences
Eva Malatinková
Jordan Thomas
Ward De Spiegelaere
Sofie Rutsaert
Anna Maria Geretti
Georgios Pollakis
William A. Paxton
Linos Vandekerckhove
Alessandra Ruggiero
A1
Artikel in een tijdschrift
in
LIFE-BASEL
2021
Motivations, barriers and experiences of participants in an HIV reservoir trial
Marie-Angélique De Scheerder
Ward P.H. van Bilsen
Melissa Dullaers
Javier Martinez-Picado
Udi Davidovich
Linos Vandekerckhove
A1
Artikel in een tijdschrift
in
JOURNAL OF VIRUS ERADICATION
2021
Organ-specific genome diversity of replication-competent SARS-CoV-2
Jolien Van Cleemput
Willem van Snippenberg
Laurens Lambrechts
Amélie Dendooven
Valentino D'Onofrio
Liesbeth Couck
Wim Trypsteen
Jan Vanrusselt
Sebastiaan Theuns
Nick Vereecke
et al.
A1
Artikel in een tijdschrift
in
NATURE COMMUNICATIONS
2021
PCIP-seq : simultaneous sequencing of integrated viral genomes and their insertion sites with long reads
Maria Artesi
Vincent Hahaut
Basiel Cole
Laurens Lambrechts
Fereshteh Ashrafi
Ambroise Marçais
Olivier Hermine
Philip Griebel
Natasa Arsic
Frank van der Meer
et al.
A1
Artikel in een tijdschrift
in
GENOME BIOLOGY
2021
Prevalence and outcomes of pregnancies in women with HIV over a 20-year period
Justyna D. Kowalska
Annegret Pelchen-Matthews
Lene Ryom
Marcelo H. Losso
Tatiana Trofimova
Viktar M. Mitsura
Irina Khromova
Dzmitry Paduta
Christoph Stephan
Pere Domingo
et al.
A1
Artikel in een tijdschrift
in
AIDS
2021
Research priorities for an HIV cure : International AIDS Society Global Scientific Strategy 2021
Steven G. Deeks
Nancie Archin
Paula Cannon
Simon Collins
R. Brad Jones
Marein A. W. P. de Jong
Olivier Lambotte
Rosanne Lamplough
Thumbi Ndung'u
Jeremy Sugarman
et al.
A1
Artikel in een tijdschrift
in
NATURE MEDICINE
2021
Robust sequential biophysical fractionation of blood plasma to study variations in the biomolecular landscape of systemically circulating extracellular vesicles across clinical conditions
Glenn Vergauwen
Joeri Tulkens
Cláudio Pinheiro
Francisco Avila Cobos
Sandor Dedeyne
Marie-Angélique De Scheerder
Linos Vandekerckhove
Francis Impens
Ilkka Miinalainen
Geert Braems
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF EXTRACELLULAR VESICLES
2021
Single cell epigenetic visualization assay
Sam Kint
Wim Van Criekinge
Linos Vandekerckhove
Winnok H De Vos
Karol Bomsztyk
Diane S Krause
Oleg Denisenko
A1
Artikel in een tijdschrift
in
NUCLEIC ACIDS RESEARCH
2021
The architecture of circulating immune cells Is dysregulated in people living with HIV on long term antiretroviral treatment and relates with markers of the HIV-1 reservoir, cytomegalovirus, and microbial tanslocation
Lisa Van de Wijer
Wouter A. van der Heijden
Rob ter Horst
Martin Jaeger
Wim Trypsteen
Sofie Rutsaert
Bram van Cranenbroek
Esther van Rijssen
Irma Joosten
Leo Joosten
et al.
A1
Artikel in een tijdschrift
in
FRONTIERS IN IMMUNOLOGY
2021
2020
CD32+CD4+memory T cells are enriched for total HIV-1 DNA in tissues from humanized mice
P. Adams
V. Fievez
R. Schober
M. Amand
G. Iserentant
Sofie Rutsaert
G. Dessilly
G. Vanham
F. Hedin
A. Cosma
et al.
A1
Artikel in een tijdschrift
in
ISCIENCE
2020
Combined assays shed new light on HIV-1 proviral sequence and linked integration site
Basiel Cole
Laurens Lambrechts
Maria Artesi
Vincent Hahaut
Wojciech Witkowski
Ytse Noppe
Annemieke Dhondt
Keith Durkin
Anne Van den Broeke
Linos Vandekerckhove
C3
Conferentie
2020
Emerging PCR-based techniques to study HIV-1 reservoir persistence
Laurens Lambrechts
Basiel Cole
Sofie Rutsaert
Wim Trypsteen
Linos Vandekerckhove
A1
Artikel in een tijdschrift
in
VIRUSES-BASEL
2020
Evaluating predictive markers for viral rebound and safety assessment in blood and lumbar fluid during HIV-1 treatment interruption
Marie-Angélique De Scheerder
Clarissa Van Hecke
Henrik Zetterberg
Dietmar Fuchs
Nele De Langhe
Sofie Rutsaert
Bram Vrancken
Wim Trypsteen
Ytse Noppe
Beatrijs Van Der Gucht
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
2020
Evolution of experimental design and research techniques in HIV-1 reservoir studies : a systematic review
Marie-Angélique De Scheerder
Bram Depelseneer
Linos Vandekerckhove
Trypsteen Wim
A1
Artikel in een tijdschrift
in
AIDS REVIEWS
2020
Exploring methods to measure DNA methylation in the context of HIV-1
Sam Kint
Wim Van Criekinge
Linos Vandekerckhove
Wim Trypsteen
Proefschrift
2020
HIV STAR : HIV-1 sequencing to identify the anatomical relevant HIV reservoir
Marie-Angélique De Scheerder
Linos Vandekerckhove
Proefschrift
2020
Increased levels of systemic LPS-positive bacterial extracellular vesicles in patients with intestinal barrier dysfunction
Joeri Tulkens
Glenn Vergauwen
Jan Van Deun
Edward Geeurickx
Bert Dhondt
Lien Lippens
Marie-Angélique De Scheerder
Ilkka Miinalainen
Pekka Rappu
Bruno De Geest
et al.
A1
Artikel in een tijdschrift
in
GUT
2020
Interferon-mediated long non-coding RNA response in macrophages in the context of HIV
Tinus Schynkel
Matthew A. Szaniawski
Adam M. Spivak
Alberto Bosque
Vicente Planelles
Linos Vandekerckhove
Wim Trypsteen
A1
Artikel in een tijdschrift
in
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2020
On the whereabouts of SARS-CoV-2 in the human body : a systematic review
Wim Trypsteen
Jolien Van Cleemput
Willem van Snippenberg
Sarah Gerlo
Linos Vandekerckhove
A1
Artikel in een tijdschrift
in
PLOS PATHOGENS
2020
Population pharmacokinetics and pharmacogenetics of ritonavir-boosted darunavir in the presence of raltegravir or tenofovir disoproxil fumarate/emtricitabine in HIV-infected adults and the relationship with virological response : a sub-study of the NEAT001/ANRS143 randomized trial
Laura Dickinson
Rohan Gurjar
Andrew Owen
Antonio D’Avolio
Gerd Fäetkenheuer
Linos Vandekerckhove
Giovanni Di Perri
the NEAT001/ANRS143 Study Group
Siegfried Schwarze
Genevieve Chene
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
2020
Rapid viral rebound after analytical treatment interruption in patients with very small HIV reservoir and minimal on-going viral transcription
Pieter Pannus
Sofie Rutsaert
Stéphane De Wit
Sabine D. Allard
Guido Vanham
Basiel Cole
Coca Nescoi
Joeri Aerts
Ward De Spiegelaere
Achilleas Tsoumanis
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF THE INTERNATIONAL AIDS SOCIETY
2020
Tackling diagnostic challenges during the first wave of COVID-19
Jozefien De Clercq
Thomas Malfait
Simon Malfait
Liselotte Coorevits
Elizaveta Padalko
Stien Vandendriessche
Bruno Verhasselt
Lieve Morbée
Fré Bauters
Katrien Hertegonne
et al.
C3
Conferentie
2020
The elusive source of HIV-1 rebound after treatment interruption
Laurens Lambrechts
Basiel Cole
Marie-Angélique De Scheerder
Zoe Boyer
Ytse Noppe
Katie Fisher
John-Sebastian Eden
Wim Van Criekinge
Lisa Frenkel
Sarah Palmer
et al.
C3
Conferentie
2020
Total HIV-1 DNA as a marker of the viral reservoir
Sofie Rutsaert
Linos Vandekerckhove
Ward De Spiegelaere
Proefschrift
2020
Underestimated effect of intragenic HIV-1 DNA methylation on viral transcription in infected individuals
Sam Kint
Wim Trypsteen
Ward De Spiegelaere
Eva Malatinková
Sabine Kinloch-de Loes
Tim De Meyer
Wim Van Criekinge
Linos Vandekerckhove
A1
Artikel in een tijdschrift
in
CLINICAL EPIGENETICS
2020
Vulnerability to reservoir reseeding due to high immune activation after allogeneic hematopoietic stem cell transplantation in individuals with HIV-1
J. M. Eberhard
M. Angin
C. Passaes
M. Salgado
V. Monceaux
E. Knops
G. Kobbe
B. Jensen
M. Christopeit
N. Kröger
et al.
A1
Artikel in een tijdschrift
in
SCIENCE TRANSLATIONAL MEDICINE
2020
Week 48 resistance analyses of the once-daily, single-tablet regimen darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) in adults living with HIV-1 from the Phase III Randomized AMBER and EMERALD Trials
Erkki Lathouwers
Eric Y Wong
Kimberley Brown
Bryan Baugh
Anne Ghys
John Jezorwski
El Ghazi Mohsine
Erika Van Landuyt
Magda Opsomer
Sandra De Meyer
et al.
A1
Artikel in een tijdschrift
in
AIDS RESEARCH AND HUMAN RETROVIRUSES
2020
Week 96 results of a phase 3 trial of darunavir/cobicistat/emtricitabine/tenofovir alafenamide in treatment-naive HIV-1 patients
C Orkin
JJ Eron
J Rockstroh
D Podzamczer
S Esser
Linos Vandekerckhove
E Van Landuyt
E Lathouwers
V Hufkens
J Jezorwski
et al.
A1
Artikel in een tijdschrift
in
AIDS
2020
2019
Analytical treatment interruption (ATI) in patients with very small HIV reservoir
Pieter Pannus
Sofie Rutsaert
Stéphane De Wit
Guido Vanham
Coca Necsoi
Joeri Aerts
Ward De Spiegelaere
Achilleas Tsoumanis
Marie Couttenye
Natacha Herssens
et al.
C3
Conferentie
2019
Decreased NEAT1 and MALAT1 levels in HIV-1 positive individuals with high viral load
Clarissa Van Hecke
Sabine Kinloch-de Loes
Tinus Schynkel
Eva Malatinková
Karen Vervisch
Sofie Rutsaert
Wim Trypsteen
Linos Vandekerckhove
C3
Conferentie
2019
Dolutegravir plus lamivudine versus dolutegravir plus tenofovir disoproxil fumarate and emtricitabine in antiretroviral-naive adults with HIV-1 infection (GEMINI-1 and GEMINI-2) : week 48 results from two multicentre, double-blind, randomised, non-inferiority, phase 3 trials
Pedro Cahn
Juan Sierra Madero
José Ramón Arribas
Andrea Antinori
Roberto Ortiz
Amanda E Clarke
Chien-Ching Hung
Jürgen K Rockstroh
Pierre-Marie Girard
Jörg Sievers
et al.
A1
Artikel in een tijdschrift
in
LANCET
2019
Early treated HIV-1 positive individuals demonstrate similar restriction factor expression profile as long-term non-progressors
Clarissa Van Hecke
Wim Trypsteen
Eva Malatinková
Ward De Spiegelaere
Karen Vervisch
Sofie Rutsaert
Sabine Kinloch-de Loes
Magdalena Sips
Linos Vandekerckhove
A1
Artikel in een tijdschrift
in
EBIOMEDICINE
2019
Establishing a hepatitis C continuum of care among HIV/hepatitis C virus-coinfected individuals in EuroSIDA
S. Amele
L. Peters
M. Sluzhynska
A. Yakovlev
A. Scherrer
P. Domingo
J. Gerstoft
J. P. Viard
M. Gisinger
R. Flisiak
et al.
A1
Artikel in een tijdschrift
in
HIV MEDICINE
2019
Evaluation of HIV-1 reservoir levels as possible markers for virological failure during boosted darunavir monotherapy
Sofie Rutsaert
Ward De Spiegelaere
Laura De Clercq
Linos Vandekerckhove
A1
Artikel in een tijdschrift
in
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
2019
Gold nanoparticle-mediated photoporation enables delivery of macromolecules over a wide range of molecular weights in human CD4+ T cells
Laurens Raes
Clarissa Van Hecke
Julie Michiels
Stephan Stremersch
Juan Fraire
Toon Brans
Ranhua Xiong
Stefaan De Smedt
Linos Vandekerckhove
Koen Raemdonck
et al.
A1
Artikel in een tijdschrift
in
CRYSTALS
2019
HIV rebound is predominantly fueled by genetically identical viral expansions from diverse reservoirs
Marie-Angélique De Scheerder
Bram Vrancken
Simon Dellicour
Timothy Schlub
Eunok Lee
Wei Shao
Sofie Rutsaert
Chris Verhofstede
Tessa Kerre
Thomas Malfait
et al.
A1
Artikel in een tijdschrift
in
CELL HOST & MICROBE
2019
Immediate versus deferred switching from a boosted protease inhibitor-based regimen to a dolutegravir-based regimen in virologically suppressed patients with high cardiovascular risk or age ≥50 years : final 96-week results of the NEAT022 study
JM Gatell
L Assoumou
G Moyle
L Waters
M Johnson
P Domingo
J Fox
E Martinez
HJ Stellbrink
G Guaraldi
et al.
A1
Artikel in een tijdschrift
in
CLINICAL INFECTIOUS DISEASES
2019
In-vitro viral suppressive capacity correlates with immune checkpoint marker expression on peripheral CD8+ T cells in treated HIV-positive patients
Pieter Pannus
Philipp Adams
Elisabeth Willems
Leo Heyndrickx
Eric Florence
Sofie Rutsaert
Ward De Spiegelaere
Linos Vandekerckhove
Carole Seguin-Devaux
Guido Vanham
A1
Artikel in een tijdschrift
in
AIDS
2019
Increased numbers of intact HIV sequences in a4b7 T cells during acute seroconversion
Sofie Rutsaert
Pilar Garcia Broncano
Marie-Angélique De Scheerder
Basiel Cole
Mathias Lichterfeld
Linos Vandekerckhove
C3
Conferentie
2019
Interferon-mediated long non-coding RNA response to HIV infection in macrophages
Tinus Schynkel
Clarissa Van Hecke
Vicente Planelles
Linos Vandekerckhove
Wim Trypsteen
C3
Conferentie
2019
Long non-coding RNAs and latent HIV : a search for novel targets for latency reversal
Wim Trypsteen
Cory H White
Amey Mukim
Celsa A Spina
Ward De Spiegelaere
Steve Lefever
Christopher H Woelk
Alberto Bosque
Linos Vandekerckhove
Nadejda Beliakova-Bethell
C3
Conferentie
2019
Long non-coding RNAs and latent HIV : a search for novel targets for latency reversal
Wim Trypsteen
Cory H White
Amey Mukim
Celsa A Spina
Ward De Spiegelaere
Steve Lefever
Vicente Planelles
Alberto Bosque
Christopher H Woelk
Linos Vandekerckhove
et al.
A1
Artikel in een tijdschrift
in
PLOS ONE
2019
Mapping acute HIV-1-infection : designing a webtool to capture multicentric & multidiscipinary data
Jozefien De Clercq
Cedric Tits
Damien Bertrand
Sophie Vanherrewege
Sofie Rutsaert
Laura Declercq
Marie-Angélique De Scheerder
Linos Vandekerckhove
C3
Conferentie
2019
Predictors of virological failure in HIV-1-infected patients switching to dolutegravir maintenance monotherapy
Ingeborg E.A. Wijting
Sofie Rutsaert
Casper Rokx
David M. Burger
Annelies Verbon
Jeroen J. A. van Kampen
Charles A. B. Boucher
Bart J. A. Rijnders
Linos Vandekerckhove
A1
Artikel in een tijdschrift
in
HIV MEDICINE
2019
Relationship between HIV-1 env sequences from rebound plasma virus and viral outgrowth
Basiel Cole
Marie-Angélique De Scheerder
Pieter Pannus
Sofie Rutsaert
Ytse Noppe
Stéphane De Wit
Sabine Allard
Guido Vanham
Eric Florence
Linos Vandekerckhove
C3
Conferentie
2019
Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive partner taking suppressive antiretroviral therapy (PARTNER) : final results of a multicentre, prospective, observational study
Alison J Rodger
Valentina Cambiano
Tina Bruun
Pietro Vernazza
Simon Collins
Olaf Degen
Giulio Maria Corbelli
Vicente Estrada
Anna Maria Geretti
Apostolos Beloukas
et al.
A1
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in
LANCET
2019
Safety, tolerability and impact on viral reservoirs of the addition to antiretroviral therapy of ABX464, an investigational antiviral drug, in individuals living with HIV-1 : a Phase IIa randomised controlled study
Sofie Rutsaert
Jean-Marc Steens
Paul Gineste
Basiel Cole
Sam Kint
P Noel Barrett
Jamal Tazi
Didier Scherrer
Hartmut J Ehrlich
Linos Vandekerckhove
A1
Artikel in een tijdschrift
in
JOURNAL OF VIRUS ERADICATION
2019
Switching from a protease inhibitor-based regimen to a dolutegravir-based regimen : a randomized clinical trial to determine the effect on peripheral blood and ileum biopsies from antiretroviral therapy-suppressed human immunodeficiency virus-infected individuals
Sara Morón-López
Jordi Navarro
Montse Jimenez
Sofie Rutsaert
Víctor Urrea
Maria C Puertas
Ariadna Torrella
Laura De Clercq
Bibiana Planas Ribas
Cristina Gálvez
et al.
A1
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in
CLINICAL INFECTIOUS DISEASES
2019
Switching to doravirine/lamivudine/tenofovir disoproxil fumarate (DOR/3TC/TDF) maintains HIV-1 virologic suppression through 48 weeks : results of the DRIVE-SHIFT trial
Margaret Johnson
Princy Kumar
Jean-Michel Molina
Giuliano Rizzardini
Pedro Cahn
Markus Bickel
Josep Mallolas
Yan Zhou
Cristiana Morais
Sushma Kumar
et al.
A1
Artikel in een tijdschrift
in
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
2019
Transcriptomic correlates of HIV reservoir size during antiretroviral therapy
Wim Trypsteen
Mohamed Abdel-Mohsen
Xutao Deng
Christopher D Pilcher
Steven G Deeks
Linos Vandekerckhove
Satish K Pillai
C3
Conferentie
2019
Uptake and effectiveness of two-drug compared with three-drug antiretroviral regimens among HIV-positive individuals in Europe
B. Neesgaard
A. Pelchen-Matthews
L. Ryom
E. Florence
L. Peters
A. Roen
V. Svedhem
A. Clarke
T. Benfield
V. Mitsura
et al.
A1
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in
AIDS
2019
Week 96 efficacy and safety results of the phase 3, randomized EMERALD trial to evaluate switching from boosted-protease inhibitors plus emtricitabine/tenofovir disoproxil fumarate regimens to the once daily, single-tablet regimen of darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) in treatment-experienced, virologically-suppressed adults living with HIV-1
Joseph J Eron
Chloe Orkin
Douglas Cunningham
Federico Pulido
Frank A Post
Stéphane De Wit
Erkki Lathouwers
Veerle Hufkens
John Jezorwski
Romana Petrovic
et al.
A1
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in
ANTIVIRAL RESEARCH
2019
2018
Abacavir usage patterns and hypersensitivity reactions in the EuroSIDA cohort
A Roen
K Laut
A Pelchen-Matthews
E Borodulina
L Caldeira
A Clarke
B Clotet
A d'Arminio Monforte
G Fätkenheuer
JM Gatell Artigas
et al.
A1
Artikel in een tijdschrift
in
HIV MEDICINE
2018
Beneficial impact of early treatment on restriction factor expression profile
Clarissa Van Hecke
Wim Trypsteen
Eva Malatinková
Ward De Spiegelaere
Karen Vervisch
Margaret Johnson
Sabine Kinloch-de Loes
Magdalena Sips
Linos Vandekerckhove
C3
Conferentie
2018
Beneficial impact of early treatment on restriction factor expression profile
Clarissa Van Hecke
Magdalena Sips
Eva Malatinková
Ward De Spiegelaere
Karen Vervisch
Margaret Johnson
Sabine Kinloch-de Loes
Wim Trypsteen
Linos Vandekerckhove
C3
Conferentie
2018
Contribution of lncRNAs in establishment of HIV latency in central memory CD4 T cells
Wim Trypsteen
Cory White
Alberto Bosque
Pieter Mestdagh
Steve Lefever
Celsa A Spina
Linos Vandekerckhove
Nadejd Beliakova-Bethell
C3
Conferentie
2018
Contribution of lncRNAs in the establishment of HIV latency in CD4+ T cell models
Wim Trypsteen
Clarissa Van Hecke
Tinus Schynkel
Cory H White
Christopher Woelk
Alberto Bosque
Celsa Spina
Steve Lefever
Pieter Mestdagh
Linos Vandekerckhove
et al.
C3
Conferentie
2018
Digital PCR as a tool to measure HIV persistence
Sofie Rutsaert
Kobus Bosman
Wim Trypsteen
Monique Nijhuis
Linos Vandekerckhove
A1
Artikel in een tijdschrift
in
RETROVIROLOGY
2018
Evaluation of bisulfite kits for DNA methylation profiling in terms of DNA fragmentation and DNA recovery using digital PCR
Sam Kint
Ward De Spiegelaere
Jonas De Kesel
Linos Vandekerckhove
Wim Van Criekinge
A1
Artikel in een tijdschrift
in
PLOS ONE
2018
Gender differences in the use of cardiovascular interventions in HIV-positive persons; the D:A:D Study
Camilla I Hatleberg
Lene Ryom
Wafaa El-Sadr
Amanda Mocroft
Peter Reiss
Stephane De Wit
Francois Dabis
Christian Pradier
Antonella d'Arminio Monforte
Helen Kovari
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF THE INTERNATIONAL AIDS SOCIETY
2018
Highlights from the HIV Cure and Reservoir Symposium, 11-12 September 2017, Ghent, Belgium
Sam Kint
Clarissa Van Hecke
Basiel Cole
Linos Vandekerckhove
Magdalena Sips
Redactioneel materiaal
2018
Impact of the HIV-1 genetic background and HIV-1 population size on the evolution of raltegravir resistance
Axel Fun
Thomas Leitner
Linos Vandekerckhove
Martin Däumer
Alexander Thielen
Bernd Buchholz
Andy IM Hoepelman
Elizabeth H Gisolf
Pauline J Schipper
Annemarie MJ Wensing
et al.
A1
Artikel in een tijdschrift
in
RETROVIROLOGY
2018
In-depth validation of total HIV-1 DNA assays for quantification of various HIV-1 subtypes
Sofie Rutsaert
Ward De Spiegelaere
Clarissa Van Hecke
Marie-Angélique De Scheerder
Maja Kiselinova
Karen Vervisch
Wim Trypsteen
Linos Vandekerckhove
A1
Artikel in een tijdschrift
in
SCIENTIFIC REPORTS
2018
Incidence of cancer and overall risk of mortality in individuals treated with raltegravir-based and non-raltegravir-based combination antiretroviral therapy regimens
A Cozzi-Lepri
R Zangerle
L Machala
K Zilmer
M Ristola
C Pradier
O Kirk
H Sambatakou
G Faetkenheuer
I Yust
et al.
A1
Artikel in een tijdschrift
in
HIV MEDICINE
2018
Long-term use of darunavir/ritonavir-containing regimens in daily practice in Belgium : retrospective observational cohort data of 1701 HIV-patients
Stéphane De Wit
Eric Florence
Linos Vandekerckhove
Bernard Vandercam
Jean-Christophe Goffard
Eric Van Wijngaerden
Michel Moutschen
Remy Demeester
Pushpike Thilakarathne
Hilde Piryns
A1
Artikel in een tijdschrift
in
ACTA CLINICA BELGICA
2018
Patient-reported outcomes in first-line antiretroviral therapy : results from NEAT001/ANRS143 trial comparing darunavir/ritonavir in combination with tenofovir/emtricitabine or raltegravir
Elizabeth C. George
Raffaella Bucciardini
Laura Richert
Nikos Dedes
Vincenzo Fragola
Pythia Nieuwkerk
Bruno Spire
Alain Volny-Anne
Brian West
Jean-Michel Molina
et al.
A1
Artikel in een tijdschrift
in
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
2018
Standardizing digital PCR diagnostics and pioneering long non-coding RNA discovery in the context of HIV cure research
Wim Trypsteen
Linos Vandekerckhove
Ward De Spiegelaere
Proefschrift
2018
Where is the greatest impact of uncontrolled HIV infection on AIDS and non-AIDS events in HIV?
Amanda Mocroft
Kamilla Laut
Peter Reiss
Jose Gatell
Vidar Ormaasen
Matthias Cavassini
Vesna Hadziosmanovic
Kamal Mansinho
Christian Pradier
Marta Vasylyev
et al.
A1
Artikel in een tijdschrift
in
AIDS
2018
Which HIV-infected adults with high CD4 T-cell counts benefit most from immediate initiation of antiretroviral therapy? : a post-hoc subgroup analysis of the START trial
Jean-Michel Molina
Birgit Grund
Fred Gordin
Ian Williams
Mauro Schechter
Marcello Losso
Matthew Law
Ernest Ekong
Noluthando Mwelase
Athanasios Skoutelis
et al.
A1
Artikel in een tijdschrift
in
LANCET HIV
2018
2017
Aggressive extensive cardiac mass in an HIV-1-infected patient : should we go for comfort therapy?
DELPHINE VERVLOET
Michel De Pauw
LAURENT DEMULIER
Jan Vercammen
Wim Terryn
EVA STEEL
Linos Vandekerckhove
A1
Artikel in een tijdschrift
in
ACTA CLINICA BELGICA
2017
Beneficial impact of early treatment on restriction factor expression profile
Clarissa Van Hecke
Magdalena Sips
Eva Malatinková
Ward De Spiegelaere
Karen Vervisch
Margaret Johnson
Sabine Kinloch-de Loes
Wim Trypsteen
Linos Vandekerckhove
C3
Conferentie
2017
Challenges of in vitro HIV latency models
Pawel Bonczkowski
Linos Vandekerckhove
Ward De Spiegelaere
Proefschrift
2017
Contribution of lncRNAs in establishment of HIV latency in central memory CD4 T cells
Wim Trypsteen
Cory White
Alberto Bosque
Celsa Spina
Steve Lefever
Pieter Mestdagh
Linos Vandekerckhove
Nadejd Beliakova-Bethell
C3
Conferentie
2017
Contribution of lncRNAs in the establishment of HIV latency in central memory CD4 T cells
Wim Trypsteen
Cory White
Alberto Bosque
Steve Lefever
Pieter Mestdagh
Linos Vandekerckhove
Christopher Woelk
C3
Conferentie
2017
Cross-validation of HIV DNA assays to quantify different HIV-1 subtypes
Sofie Rutsaert
Ward De Spiegelaere
Clarissa Van Hecke
Marie-Angélique De Scheerder
Maja Kiselinova
Karen Vervisch
Wim Trypsteen
Linos Vandekerckhove
C3
Conferentie
2017
Defining a Total HIV DNA threshold as guidance for therapy simplification strategies
Sofie Rutsaert
Ingeborg Wijting
Ward De Spiegelaere
Laura De Clercq
Bart Rijnders
Linos Vandekerckhove
C3
Conferentie
2017
Differential expression of lncRNAs during the HIV replication cycle: an underestimated layer in the HIV-host interplay (vol 6, 36111, 2016)
Wim Trypsteen
Pejman Mohammadi
Clarissa Van Hecke
Pieter Mestdagh
Steve Lefever
Yvan Saeys
Pieter De Bleser
Jo Vandesompele
Angela Ciuffi
Linos Vandekerckhove
et al.
Correctie
2017
Fight fire with fire : gene therapy strategies to cure HIV
Jon Huyghe
Magdalena Sips
Linos Vandekerckhove
A1
Artikel in een tijdschrift
in
EXPERT REVIEW OF ANTI-INFECTIVE THERAPY
2017
HIV DNA as a predictive marker for virological failure of darunavir/r monotherapy : a substudy of the PROTEA trial to define a cut-off for succes
Sofie Rutsaert
Ward De Spiegelaere
Laura De Clercq
Linos Vandekerckhove
C3
Conferentie
2017
HIV integration sites in latently infected cell lines : evidence of ongoing replication
Jori Symons
Abha Chopra
Eva Malatinková
Ward De Spiegelaere
Shay Leary
Don Cooper
Chike O Abana
Ajantha Rhodes
Simin D Rezaei
Linos Vandekerckhove
et al.
A1
Artikel in een tijdschrift
in
RETROVIROLOGY
2017
HIV reservoir characterization symposium 19 September 2016, Ghent, Belgium
Eva Malatinková
Ward De Spiegelaere
Linos Vandekerckhove
Magdalena Sips
A1
Artikel in een tijdschrift
in
JOURNAL OF VIRUS ERADICATION
2017
Highlights from the 24th conference on retroviruses and opportunistic infections, 13-16 February 2017, Seattle, Washington, USA
Trevor A Crowell
Hermione Lyall
Eva Malatinková
Sanjay Bhagani
Denise Hsu
Donn J Colby
Christina Polyak
Christina Psomas
Andrew Hill
Esther N Gathogo
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF VIRUS ERADICATION
2017
Raltegravir 1200 mg once daily versus raltegravir 400 mg twice daily, with tenofovir disoproxil fumarate and emtricitabine, for previously untreated HIV-1 infection : a randomised, double-blind, parallel-group, phase 3, non-inferiority trial
Pedro Cahn
Richard Kaplan
Paul E Sax
Kathleen Squires
Jean-Michel Molina
Anchalee Avihingsanon
Winai Ratanasuwan
Evelyn Rojas
Mohammed Rassool
Mark Bloch
et al.
A1
Artikel in een tijdschrift
in
LANCET HIV
2017
Short-course Toll-like receptor 9 agonist treatment impacts innate immunity and plasma viremia in individuals with human immunodeficiency virus infection
Line Vibholm
Mariane H Schleimann
Jesper F Højen
Thomas Benfield
Rasmus Offersen
Katrine Rasmussen
Rikke Olesen
Anders Dige
Jørgen Agnholt
Judith Grau
et al.
A1
Artikel in een tijdschrift
in
CLINICAL INFECTIOUS DISEASES
2017
The expression profile of host restriction factors in different cohorts of HIV-1 infected patients
Clarissa Van Hecke
Eva Malatinková
Margaret Johnson
Sabine Kinloch-de Loes
Wim Trypsteen
Linos Vandekerckhove
C3
Conferentie
2017
Utility of integrated HIV-1 DNA quantification in cure studies
Alessandra Ruggiero
Eva Malatinková
Sofie Rutsaert
William A Paxton
Linos Vandekerckhove
Ward De Spiegelaere
A1
Artikel in een tijdschrift
in
FUTURE VIROLOGY
2017
lncRNA discovery in the HIV replication cycle adds new layer in HIV-host interplay
Wim Trypsteen
Mohammadi Pejman
Clarissa Van Hecke
Pieter Mestdagh
Steve Lefever
Pieter De Bleser
Jo Vandesompele
Angela Ciuffi
Ward De Spiegelaere
Linos Vandekerckhove
C3
Conferentie
2017
2016
Antiretroviral resistance at virological failure in the NEAT 001/ANRS 143 trial : raltegravir plus darunavir/ritonavir or tenofovir/emtricitabine plus darunavir/ritonavir as first-line ART
S Lambert-Niclot
EC George
A Pozniak
E White
C Schwimmer
H Jessen
M Johnson
D Dunn
CF Perno
B Clotet
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
2016
Cumulative and current exposure to potentially nephrotoxic antiretrovirals and development of chronic kidney disease in HIV-positive individuals with a normal baseline estimated glomerular filtration rate : a prospective international cohort study
Amanda Mocroft
Jens D Lundgren
Michael Ross
Christoph A Fux
Peter Reiss
Olivier Moranne
Philippe Morlat
Antonella d'Arminio Monforte
Ole Kirk
Lene Ryom
et al.
A1
Artikel in een tijdschrift
in
LANCET HIV
2016
Diagnostic utility of droplet digital PCR for HIV reservoir quantification
Wim Trypsteen
Maja Kiselinova
Linos Vandekerckhove
Ward De Spiegelaere
A2
Artikel in een tijdschrift
in
JOURNAL OF VIRUS ERADICATION
2016
Differential expression of lncRNAs during the HIV replication cycle : an underestimated layer in the HIV-host interplay
Wim Trypsteen
Pejman Mohammadi
Clarissa Van Hecke
Pieter Mestdagh
Steve Lefever
Yvan Saeys
Pieter De Bleser
Jo Vandesompele
Angela Ciuffi
Linos Vandekerckhove
et al.
A1
Artikel in een tijdschrift
in
SCIENTIFIC REPORTS
2016
Disparities in HIV clinic care across Europe : findings from the EuroSIDA clinic survey
Jeffrey V Lazarus
Kamilla Grønborg Laut
Kelly Safreed-Harmon
Lars Peters
Margaret Johnson
Gerd Fätkenheuer
Irina Khromova
Linos Vandekerckhove
Katarzyna Maciejewska
Roxana Radoi
et al.
A1
Artikel in een tijdschrift
in
BMC INFECTIOUS DISEASES
2016
HIV-1 Vpr N-terminal tagging affects alternative splicing of the viral genome
Ann Baeyens
Evelien Naessens
Anouk Van Nuffel
Karin Weening
Anne-Marie Reilly
Eva Claeys
Wim Trypsteen
Linos Vandekerckhove
Sven Eyckerman
Kris Gevaert
et al.
A1
Artikel in een tijdschrift
in
SCIENTIFIC REPORTS
2016
Highlights from the conference on retroviruses and opportunistic infections 2016 : 22-25 February 2016, Boston, Massachusetts, USA
S Fidler
J Ananworanich
Linos Vandekerckhove
Maja Kiselinova
A Schuetz
JH Vera
E Dwyer
J Alagaratnam
Redactioneel materiaal
2016
Host and disease factors are associated with cognitive function in European HIV-infected adults prior to initiation of antiretroviral therapy
A Winston
W Stöhr
A Antinori
A Arenas-Pinto
JM Libre
H Amieva
A Cabie
I Williams
G Di Perri
MJ Tellez
et al.
A1
Artikel in een tijdschrift
in
HIV MEDICINE
2016
In search of predictive biomarkers of the replication-competent HIV-1 reservoir
Maja Kiselinova
Linos Vandekerckhove
Ward De Spiegelaere
Proefschrift
2016
Infection-related and -unrelated malignancies, HIV and the aging population
L Shepherd
A Borges
B Ledergerber
P Domingo
A Castagna
J Rockstroh
B Knysz
J Tomazic
I Karpov
O Kirk
et al.
A1
Artikel in een tijdschrift
in
HIV MEDICINE
2016
Integrated and total HIV-1 DNA predict ex vivo viral outgrowth
Maja Kiselinova
Ward De Spiegelaere
Maria Jose Buzon
Eva Malatinková
Mathias Lichterfeld
Linos Vandekerckhove
A1
Artikel in een tijdschrift
in
PLOS PATHOGENS
2016
Late presentation to HIV testing is overestimated when based on the consensus definition
A Sasse
E Florence
A Pharris
S De Wit
P Lacor
D Van Beckhoven
J Deblonde
M-L Delforge
K Fransen
J-C Goffard
et al.
A1
Artikel in een tijdschrift
in
HIV MEDICINE
2016
Minimal requirements for primary HIV latency models based on a systematic review
Pawel Bonczkowski
Marie-Angélique De Scheerder
Ward De Spiegelaere
Linos Vandekerckhove
A1
Artikel in een tijdschrift
in
AIDS REVIEWS
2016
Modeling HIV-1 latency in primary T cells using a replication-competent virus
Laura Martins
Pawel Bonczkowski
Adam M Spivak
Ward De Spiegelaere
Camille L Novis
Ana Beatriz DePaula-Silva
Eva Malatinková
Wim Trypsteen
Alberto Bosque
Linos Vandekerckhove
et al.
A1
Artikel in een tijdschrift
in
AIDS RESEARCH AND HUMAN RETROVIRUSES
2016
Protein expression from unintegrated HIV-1 DNA introduces bias in primary in vitro post-integration latency models
Pawel Bonczkowski
Marie-Angélique De Scheerder
Eva Malatinková
Alexandra Borch
Zora Melkova
Renate Koenig
Ward De Spiegelaere
Linos Vandekerckhove
A1
Artikel in een tijdschrift
in
SCIENTIFIC REPORTS
2016
Sexual activity without condoms and risk of HIV transmission in serodifferent couples when the HIV-positive partner is using suppressive antiretroviral therapy
AJ Rodger
V Cambiano
T Bruun
P Vernazza
S Collins
J van Lunzen
GM Corbelli
V Estrada
AM Geretti
A Beloukas
et al.
A1
Artikel in een tijdschrift
in
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
2016
The future of digital polymerase chain reaction in virology
Matthijs Vynck
Wim Trypsteen
Olivier Thas
Linos Vandekerckhove
Ward De Spiegelaere
A1
Artikel in een tijdschrift
in
MOLECULAR DIAGNOSIS & THERAPY
2016
The long lasting impact of early treatment initiation on the size and dynamics of HIV-1 reservoirs
Eva Malatinková
Linos Vandekerckhove
Ward De Spiegelaere
Proefschrift
2016
The use of HIV-1 integration site analysis information in clinical studies aiming at HIV cure
Maja Kiselinova
Ward De Spiegelaere
Linos Vandekerckhove
A2
Artikel in een tijdschrift
in
JOURNAL OF VIRUS ERADICATION
2016
Transmission of HIV drug resistance and the predicted effect on current first-line regimens in Europe
L Marije Hofstra
Nicolas Sauvageot
Jan Albert
Ivailo Alexiev
Federico Garcia
Daniel Struck
David AMC Van de Vijver
Birgitta Åsjö
Danail Beshkov
Suzie Coughlan
et al.
A1
Artikel in een tijdschrift
in
CLINICAL INFECTIOUS DISEASES
2016
2015
Accurate quantification of episomal HIV-1 two-long terminal repeat circles by use of optimized DNA isolation and droplet digital PCR
Eva Malatinková
Maja Kiselinova
Pawel Bonczkowski
Wim Trypsteen
Peter Messiaen
Jolien Vermeire
Bruno Verhasselt
KAREN VERVISCH
Linos Vandekerckhove
Ward De Spiegelaere
A1
Artikel in een tijdschrift
in
JOURNAL OF CLINICAL MICROBIOLOGY
2015
Aviremia 10 years postdiscontinuation of antiretroviral therapy initiated during primary human immunodeficiency virus-1 infection and association with gag-specific T-cell responses
Sabine Kinloch-de Loes
Lucy Dorell
Hongbing Yang
Gareth AD Hardy
Sabine Yerly
Cristina Cellerai
Linos Vandekerckhove
Ward De Spiegelaere
Eva Malatinková
Willie Wee Lee Koh
et al.
A1
Artikel in een tijdschrift
in
OPEN FORUM INFECTIOUS DISEASES
2015
Aviremia 10-year post-ART discontinuation initiated at seroconversion
Sabine Kinloch
Lucy Dorrel
Hongbing Yang
Linos Vandekerckhove
Ward De Spiegelaere
Eva Malatinkova
Sabine Yerly
Daniel Webster
Margaret Johnson
C3
Conferentie
2015
Changing utilization of Stavudine (d4T) in HIV-positive people in 2006-2013 in the EuroSIDA study
D Podlekareva
D Grint
I Karpov
A Rakmanova
K Mansinho
N Chentsova
I Zeltina
M Losso
M Parczewski
JD Lundgren
et al.
A1
Artikel in een tijdschrift
in
HIV MEDICINE
2015
Comparison of digital PCR platforms and semi-nested qPCR as a tool to determine the size of the HIV reservoir
Kobus J Bosman
Monique Nijhuis
Petra M Van Ham
Annemarie MJ Wensing
KAREN VERVISCH
Linos Vandekerckhove
Ward De Spiegelaere
A1
Artikel in een tijdschrift
in
SCIENTIFIC REPORTS
2015
Comparison of methods for in-house screening of HLA*B57:01 to prevent abacavir hypersensitivity in HIV-1 care
Ward De Spiegelaere
Jan Philippé
KAREN VERVISCH
Chris Verhofstede
Eva Malatinková
Maja Kiselinova
Wim Trypsteen
Pawel Bonczkowski
Dirk Vogelaers
Steven Callens
et al.
A1
Artikel in een tijdschrift
in
PLOS ONE
2015
Comprehensive longitudinal characterization of HIV-1 reservoir markers in patients on stable antiretroviral treatment
Maja Kiselinova
Ward De Spiegelaere
Maria Jose Buzon
Eva Malatinková
Mathias Lichterfeld
Linos Vandekerckhove
C3
Conferentie
2015
Drug resistance is rarely the cause or consequence of long-term persistent low-level viraemia in HIV-1-infected patients on ART
Leen Vancoillie
Virginie Mortier
Els Demecheleer
Marlies Schauvliege
Linos Vandekerckhove
Dirk Vogelaers
Chris Verhofstede
A1
Artikel in een tijdschrift
in
ANTIVIRAL THERAPY
2015
During stably suppressive antiretroviral therapy integrated HIV-1 DNA load in peripheral blood is associated with the frequency of CD8 cells expressing HLA-DR/DP/DQ
Alessandra Ruggiero
Ward De Spiegelaere
Alessandro Cozzi-Lepri
Maja Kiselinova
Georgios Pollakis
Apostolos Beloukas
Linos Vandekerckhove
Matthew Strain
Douglas Richman
Andrew Phillips
et al.
A1
Artikel in een tijdschrift
in
EBIOMEDICINE
2015
Efficacy of tenofovir and efavirenz in combination with lamivudine or emtricitabine in antiretroviral-naive patients in Europe
JE Swartz
Linos Vandekerckhove
H Ammerlaan
AC de Vries
J Begovac
WFW Bierman
CAB Boucher
ME van der Ende
Z Grossman
R Kaiser
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
2015
Extreme value theory for threshold determination in droplet digital PCR experiments
Matthijs Vynck
Wim Trypsteen
Jan De Neve
Pawel Bonczkowski
Maja Kiselinova
Eva Malatinková
KAREN VERVISCH
Olivier Thas
Linos Vandekerckhove
Ward De Spiegelaere
C3
Conferentie
2015
Fluoxetine suppresses calcium signaling in human T lymphocytes through depletion of intracellular calcium stores
Veerle Gobin
Marijke De Bock
Bart Broeckx
Maja Kiselinova
Ward De Spiegelaere
Linos Vandekerckhove
Katleen Van Steendam
Luc Leybaert
Dieter Deforce
A1
Artikel in een tijdschrift
in
CELL CALCIUM
2015
HIV resistance testing and detected drug resistance in Europe
Anna Schultze
Andrew N Phillips
Roger Paredes
Manuel Battegay
Jürgen K Rockstroh
Ladislav Machala
Janez Tomazic
Pierre M Girard
Inga Januskevica
Kamilla Gronborg-Laut
et al.
A1
Artikel in een tijdschrift
in
AIDS
2015
HIV-1 RNA and HIV-1 DNA persistence during suppressive ART with PI-based or nevirapine-based regimens
Maja Kiselinova
Anna Maria Geretti
Eva Malatinková
KAREN VERVISCH
Apostolos Beloukas
Peter Messiaen
Pawel Bonczkowski
Wim Trypsteen
Steven Callens
Chris Verhofstede
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
2015
Impact of a decade of successful antiretroviral therapy initiated at HIV-1 seroconversion on blood and mucosal reservoirs
Eva Malatinková
Ward De Spiegelaere
Pawel Bonczkowski
Maja Kiselinova
Wim Trypsteen
Margaret Johnson
Chris Verhofstede
Danny De Looze
Charles Murray
Sabine Kinloch-de Loes
et al.
A1
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in
ELIFE
2015
Impact of a decade of successful antiretroviral therapy started during HIV-1 seroconversion on blood and gut reservoirs
Sabine Kinloch-de Loes
Eva Malatinková
Ward De Spiegelaere
Pawel Bonczkowski
Maja Kiselinova
KAREN VERVISCH
Wim Trypsteen
Margaret Johnson
Danny De Looze
Linos Vandekerckhove
C3
Conferentie
2015
Integration site analysis of latently infected cell lines: evidence of ongoing replication
Jory Symons
Sharon Lewin
Abha Chopra
Eva Malatinková
Ward De Spiegelaere
Shay Leary
David Cooper
Linos Vandekerckhove
Simon Mallal
Paul Cameron
C3
Conferentie
2015
Long-term early antiretroviral therapy limits the HIV-1 reservoir size as compared to later treatment initiation but not to levels found in long-term non-progressors
Eva Malatinková
Ward De Spiegelaere
Pawel Bonczkowski
Maja Kiselinova
KAREN VERVISCH
Wim Trypsteen
Margaret Johnson
Chris Verhofstede
Danny De Looze
Charles Murray
et al.
C3
Conferentie
2015
Primary resistance to integrase strand-transfer inhibitors in Europe
M Casadellà
PM van Ham
M Noguera-Julian
A van Kessel
C Pou
LM Hofstra
JR Santos
F Garcia
D Struck
I Alexiev
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
2015
Reference gene validation for RT-qPCR, a note on different available software packages
Ward De Spiegelaere
Jutta Dern-Wieloch
Roswitha Weigel
Valérie Schumacher
Hubert Schorle
Daniel Nettersheim
Martin Bergmann
Ralph Brehm
Sabine Kliesch
Linos Vandekerckhove
et al.
A1
Artikel in een tijdschrift
in
PLOS ONE
2015
Robust regression methods for real-time PCR
Wim Trypsteen
Jan De Neve
Kobus Bosman
Monique Nijhuis
Olivier Thas
Linos Vandekerckhove
Ward De Spiegelaere
C3
Conferentie
2015
Robust regression methods for real-time polymerase chain reaction
Wim Trypsteen
Jan De Neve
Kobus Bosman
Monique Nijhuis
Olivier Thas
Linos Vandekerckhove
Ward De Spiegelaere
A1
Artikel in een tijdschrift
in
ANALYTICAL BIOCHEMISTRY
2015
Th1/17 polarization of CD4 T cells supports HIV-1 persistence during antiretroviral therapy
Hong Sun
Dhohyung Kim
Xiaodong Li
Maja Kiselinova
Zhengyu Ouyang
Linos Vandekerckhove
Hong Shang
Eric S Rosenberg
Xu G Yu
Mathias Lichterfeld
A1
Artikel in een tijdschrift
in
JOURNAL OF VIROLOGY
2015
Threshold determination in droplet digital PCR experiments using extreme value theory
Matthijs Vynck
Wim Trypsteen
Jan De Neve
Pawel Bonczkowski
Maja Kiselinova
Eva Malatinková
KAREN VERVISCH
Olivier Thas
Linos Vandekerckhove
Ward De Spiegelaere
C3
Conferentie
2015
ddcRquant: threshold determination for single channel droplet digital PCR experiments
Wim Trypsteen
Matthijs Vynck
Jan De Neve
Pawel Bonczkowski
Maja Kiselinova
Eva Malatinková
KAREN VERVISCH
Olivier Thas
Linos Vandekerckhove
Ward De Spiegelaere
C3
Conferentie
2015
ddpcRquant: threshold determination for single channel droplet digital PCR experiments
Wim Trypsteen
Matthijs Vynck
Jan De Neve
Pawel Bonczkowski
Maja Kiselinova
Eva Malatinková
KAREN VERVISCH
Olivier Thas
Linos Vandekerckhove
Ward De Spiegelaere
A1
Artikel in een tijdschrift
in
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
2015
2014
A survey of ATRIPLA use in clinical practice as first-line therapy in HIV-positive persons in Europe
A Mocroft
P Reiss
A Rakhmanova
D Banhegyi
AN Phillips
S De Wit
M Ristola
JD Lundgren
J Grarup
O Kirk
et al.
A1
Artikel in een tijdschrift
in
INFECTION
2014
Accurate episomal HIV 2-LTR circles quantification using optimized DNA isolation and droplet digital PCR
Eva Malatinková
Maja Kiselinova
Pawel Bonczkowski
Wim Trypsteen
Peter Messiaen
Jolien Vermeire
Bruno Verhasselt
Karen Vervisch
Linos Vandekerckhove
Ward De Spiegelaere
C3
Conferentie
2014
Antiretrovirals for HIV prevention: when should they be recommended?
Maja Kiselinova
Ward De Spiegelaere
Chris Verhofstede
Steven Callens
Linos Vandekerckhove
A1
Artikel in een tijdschrift
in
EXPERT REVIEW OF ANTI-INFECTIVE THERAPY
2014
Characterization of serotonin transporter expression in human T lymphocytes
Veerle Gobin
Katleen Van Steendam
Maja Kiselinova
Ward De Spiegelaere
Linos Vandekerckhove
Dieter Deforce
C3
Conferentie
2014
Comparative performances of HIV-1 RNA load assays at low viral load levels: results of an international collaboration
Luke C Swenson
Bryan Cobb
Anna Maria Geretti
P Richard Harrigan
Mario Poljak
Carole Seguin-Devaux
Chris Verhofstede
Marc Wirden
Alessandra Amendola
Jurg Boni
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF CLINICAL MICROBIOLOGY
2014
Comparison of droplet digital PCR and seminested real-time PCR for quantification of cell-associated HIV-1 RNA
Maja Kiselinova
Alexander O Pasternak
Ward De Spiegelaere
Dirk Vogelaers
Ben Berkhout
Linos Vandekerckhove
A1
Artikel in een tijdschrift
in
PLOS ONE
2014
Dependence on the CCR5 coreceptor for viral replication explains the lack of rebound of CXCR4-predicted HIV variants in the Berlin patient
Jori Symons
Linos Vandekerckhove
Gero Hutter
Annemarie MJ Wensing
Petra M van Ham
Steven G Deeks
Monique Nijhuis
A1
Artikel in een tijdschrift
in
CLINICAL INFECTIOUS DISEASES
2014
Deteriorating renal function and clinical outcomes in HIV-positive persons
Amanda Mocroft
Lene Ryom
Josip Begovac
Antonella D'Arminio Monforte
Anne Vassilenko
Jose Gatell
Eric Florence
Vidar Ormaasen
Ole Kirk
Jens D Lundgren
et al.
A1
Artikel in een tijdschrift
in
AIDS
2014
Development of a definition for Rapid Progression (RP) of renal function in HIV-positive persons: the D:A:D study
David A Kamara
Lene Ryom
Michael Ross
Ole Kirk
Peter Reiss
Philippe Morlat
Olivier Moranne
Christoph A Fux
Amanda Mocroft
Caroline Sabin
et al.
A1
Artikel in een tijdschrift
in
BMC NEPHROLOGY
2014
Disseminated infection with Mycobacterium tilburgii in a male immunocompromised patient
SARAH TEMMERMAN
Linos Vandekerckhove
ERICA SERMIJN
Dirk Vogelaers
Geert Claeys
Mario Vaneechoutte
Piet Cools
Steven Callens
A1
Artikel in een tijdschrift
in
JOURNAL OF CLINICAL MICROBIOLOGY
2014
Factors associated with the continuum of care of HIV infected patients in Belgium
Dominique Van Beckhoven
Patrick Lacor
Michel Moutschen
Denis Piérard
André Sasse
Dolorès Vaira
Sigi Van den Wijngaert
Bernard Vandercam
Marc Van Ranst
Eric Van Wijngaerden
et al.
C3
Conferentie
2014
Immuno-virological discordance and the risk of non-AIDS and AIDS events in a large observational cohort of HIV-patients in Europe
Alexander Zoufaly
Alessandro Cozzi-Lepri
Joanne Reekie
Ole Kirk
Jens Lundgren
Peter Reiss
Djordje Jevtovic
Ladislav Machala
Robert Zangerle
Amanda Mocroft
et al.
A1
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in
PLOS ONE
2014
Implementation of a multidisciplinary infectious diseases team in a tertiary hospital within an Antimicrobial Stewardship Program
Franky Buyle
MATTHIAS WALLAERT
NATHALIE BECK
Jerina Boelens
Steven Callens
Geert Claeys
SABINE DERYCKERE
EVELIEN HAEGEMAN
Isabel Leroux-Roels
ERICA SERMIJN
et al.
A1
Artikel in een tijdschrift
in
ACTA CLINICA BELGICA
2014
Increase in transmitted resistance to non-nucleoside reverse transcriptase inhibitors among newly diagnosed HIV-1 infections in Europe
Dineke Frentz
David AMC Van de Vijver
Ana B Abecasis
Jan Albert
Osamah Hamouda
Louise B Jørgensen
Claudia Kücherer
Daniel Struck
Jean-Claude Schmit
Jurgen Vercauteren
et al.
A1
Artikel in een tijdschrift
in
BMC INFECTIOUS DISEASES
2014
Increased incidence of antiretroviral drug discontinuation among patients with viremic hepatitis C virus coinfection and high hyaluronic acid, a marker of liver fibrosis
Daniel Grint
Lars Peters
Juergen K Rockstroh
Stephane De Wit
Victor M Mitsura
Brygida Knysz
Court Pedersen
Ole Kirk
Jens D Lundgren
Amanda Mocroft
et al.
A1
Artikel in een tijdschrift
in
AIDS
2014
Increased risk of cardiovascular disease (CVD) with age in HIV-positive men: a comparison of the D:A:D CVD risk equation and general population CVD risk equations
K Petoumenos
P Reiss
L Ryom
M Rickenbach
CA Sabin
W El-Sadr
AD Monforte
AN Phillips
S De Wit
O Kirk
et al.
A1
Artikel in een tijdschrift
in
HIV MEDICINE
2014
Markers associated with persisting low-level viraemia under antiretroviral therapy in HIV-1 infection
Leen Vancoillie
Els Demecheleer
Steven Callens
Dirk Vogelaers
Linos Vandekerckhove
Virginie Mortier
Chris Verhofstede
A1
Artikel in een tijdschrift
in
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
2014
Patterns of transmitted HIV drug resistance in Europe vary by risk group
Dineke Frentz
David van de Vijver
Ana Abecasis
Jan Albert
Osamah Hamouda
Louise Jørgensen
Claudia Kücherer
Daniel Struck
Jean-Claude Schmit
Jurgen Vercauteren
et al.
A1
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in
PLOS ONE
2014
Processing of blood samples influences PBMC viability and outcome of cell-mediated immune responses in antiretroviral therapy-naïve HIV-1-infected patients
Patricia Bourguignon
Frédéric Clement
Frédéric Renaud
Vivien Le Bras
Marguerite Koutsoukos
Wivine Burny
Philippe Moris
Clarisse Lorin
Alix Collard
Geert Leroux-Roels
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF IMMUNOLOGICAL METHODS
2014
Prognostic value of vitamin D level for all-cause mortality, and association with inflammatory markers, in HIV-infected persons
Leah Shepherd
Jean-Claude Souberbielle
Jean-Philippe Bastard
Soraya Fellahi
Jaqueline Capeau
Joanne Reekie
Peter Reiss
Anders Blaxhult
Markus Bickel
Clifford Leen
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF INFECTIOUS DISEASES
2014
Quantification of integrated HIV DNA by repetitive-sampling Alu-HIV PCR on the basis of Poisson statistics
Ward De Spiegelaere
Eva Malatinková
Lindsay Lynch
Filip Van Nieuwerburgh
Peter Messiaen
Una O'Doherty
Linos Vandekerckhove
A1
Artikel in een tijdschrift
in
CLINICAL CHEMISTRY
2014
Replication competent virus as an important source of bias in HIV latency models utilizing single round viral constructs
Pawel Bonczkowski
Ward De Spiegelaere
Alberto Bosque
Cory H White
Anouk Van Nuffel
Eva Malatinková
Maja Kiselinova
Wim Trypsteen
Wojciech Witkowski
Jolien Vermeire
et al.
A1
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in
RETROVIROLOGY
2014
Ritonavir-boosted darunavir combined with raltegravir or tenofovir-emtricitabine in antiretroviral-naive adults infected with HIV-1: 96 week results from the NEAT001/ANRS143 randomised non-inferiority trial
François Raffi
Abdel G Babiker
Laura Richert
Jean-Michel Molina
Elizabeth C George
Andrea Antinori
Jose R Arribas
Jesper Grarup
Fleur Hudson
Christine Schwimmer
et al.
A1
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in
LANCET
2014
The impact of nevirapine- versus protease inhibitor-based regimens on virological markers of HIV-1 persistence during seemingly suppressive ART
Maja Kiselinova
Maria Anna
Eva Malatinková
KAREN VERVISCH
Apostolos Beloukas
Peter Messiaen
Pawel Bonczkowski
Wim Trypsteen
Steven Callens
Chris Verhofstede
et al.
C3
Conferentie
2014
Thrombocytopenia is associated with an increased risk of cancer during treated HIV disease
Álvaro H Borges
Jens D Lundgren
Annalisa Ridolfo
Christine Katlama
Francisco Antunes
Anna Grzeszczuk
Anders Blaxhult
Viktar M Mitsura
Manuela Doroana
Manuel Battegay
et al.
A1
Artikel in een tijdschrift
in
AIDS
2014
Trends in underlying causes of death in people with HIV from 1999 to 2011 (D:A:D) : a multicohort collaboration
CJ Smith
L Ryom
R Weber
P Morlat
C Pradier
P Reiss
JD Kowalska
S de Wit
M Law
W el Sadr
et al.
A1
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in
LANCET
2014
2013
A translational approach to new diagnostic tools and therapies for HIV care
Peter Messiaen
Linos Vandekerckhove
Dirk Vogelaers
Proefschrift
2013
Association between antiretroviral exposure and renal impairment among HIV-positive persons with normal baseline renal function: the D:A:D study
Lene Ryom
Amanda Mocroft
Ole Kirk
Signe W Worm
David A Kamara
Peter Reiss
Michael Ross
Christoph A Fux
Philippe Morlat
Olivier Moranne
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF INFECTIOUS DISEASES
2013
Associations between immune depression and cardiovascular events in HIV infection
Caroline A Sabin
Lene Ryom
Stephane De Wit
Amanda Mocroft
Andrew N Phillips
Signe W Worm
Rainer Weber
Antonella D'Arminio Monforte
Peter Reiss
David Kamara
et al.
A1
Artikel in een tijdschrift
in
AIDS
2013
Boosted protease inhibitor monotherapy in HIV-infected adults: outputs from a pan-European expert panel meeting
José R Arribas
Manuela Doroana
Dan Turner
Linos Vandekerckhove
Adrian Streinu-Cercel
A1
Artikel in een tijdschrift
in
AIDS RESEARCH AND THERAPY
2013
CD4 cell count and viral load-specific rates of AIDS, non-AIDS and deaths according to current antiretroviral use
Amanda Mocroft
Andrew N Phillips
Jose Gatell
Andrej Horban
Bruno Ledergerber
Kai Zilmer
Djordje Jevtovic
Fernando Maltez
Daria Podlekareva
Jens D Lundgren
et al.
A1
Artikel in een tijdschrift
in
AIDS
2013
Calciphylaxis: a rare complication in alcoholic liver disease
ERICA SERMIJN
TINE STROBBE
Linos Vandekerckhove
Louis Libbrecht
Isabelle Colle
R Schoonjans
Dirk Vogelaers
A1
Artikel in een tijdschrift
in
ACTA CLINICA BELGICA
2013
Clinical use of HIV integrase inhibitors : a systematic review and meta-analysis
Peter Messiaen
Annemarie MJ Wensing
Axel Fun
Monique Nijhuis
Nele Brusselaers
Linos Vandekerckhove
A1
Artikel in een tijdschrift
in
PLOS ONE
2013
Cutaneous metastatic tuberculous abcess in a patient with cervico-mediastinal lymphatic tuberculosis
SVEN DEKEYZER
F Moerman
Steven Callens
Linos Vandekerckhove
A1
Artikel in een tijdschrift
in
ACTA CLINICA BELGICA
2013
Dolutegravir plus abacavir-lamivudine for the treatment of HIV-1 infection
Sharon L Walmsley
Antonio Antela
Nathan Clumeck
Dan Duiculescu
Andrea Eberhard
Felix Gutiérrez
Laurent Hocqueloux
Franco Maggiolo
Uriel Sandkovsky
Catherine Granier
et al.
A1
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in
NEW ENGLAND JOURNAL OF MEDICINE
2013
Droplet digital PCR, the new tool in HIV reservoir quantification?
Ward De Spiegelaere
Maja Kiselinova
Eva Malatinková
Alexander Pasternak
Ben Berkhout
Linos Vandekerckhove
C3
Conferentie
2013
Frequency and predictors of HIV-1 co-receptor switch in treatment naive patients
Virginie Mortier
Kenny Dauwe
Leen Vancoillie
Delfien Staelens
Filip Van Wanzeele
Dirk Vogelaers
Linos Vandekerckhove
Kristen Chalmet
Chris Verhofstede
A1
Artikel in een tijdschrift
in
PLOS ONE
2013
Limited cross-border infections in patients newly diagnosed with HIV in Europe
Dineke Frentz
Annemarie MJ Wensing
Jan Albert
Dimitrios Paraskevis
Ana B Abecasis
Osamah Hamouda
Louise B Jørgensen
Claudia Kücherer
Daniel Struck
Jean-Claude Schmit
et al.
A1
Artikel in een tijdschrift
in
RETROVIROLOGY
2013
Non-AIDS defining cancers in the D:A:D Study : time trends and predictors of survival: a cohort study
Signe W Worm
Mark Bower
Peter Reiss
Fabrice Bonnet
Matthew Law
Gerd Fätkenheuer
Antonella d'Arminio Monforte
Donald I Abrams
Andrew Grulich
Eric Fontas
et al.
A1
Artikel in een tijdschrift
in
BMC INFECTIOUS DISEASES
2013
Polyfunctional CD4⁺ T cell responses in HIV-1 infected viral controllers compared with those in healthy recipients of an adjuvanted polyprotein HIV-1 vaccine
Eva Van Braeckel
Isabelle Desombere
Frédéric Clement
Linos Vandekerckhove
Chris Verhofstede
Dirk Vogelaers
Geert Leroux-Roels
A1
Artikel in een tijdschrift
in
VACCINE
2013
Quantification of integrated HIV DNA by repetitive sampling Alu-HIV PCR and Poisson statistics
Ward De Spiegelaere
Eva Malatinková
Filip Van Nieuwerburgh
Una O'Doherty
Linos Vandekerckhove
C3
Conferentie
2013
Stability of hepatitis C virus (HCV) RNA levels among interferon-naïve HIV/HCV-coinfected individuals treated with combination antiretroviral therapy
D Grint
L Peters
J Reekie
V Soriano
O Kirk
B Knysz
O Suetnov
A Lazzarin
B Ledergerber
JK Rockstroh
et al.
A1
Artikel in een tijdschrift
in
HIV MEDICINE
2013
Temporal changes and regional differences in treatment uptake of hepatitis C therapy in EuroSIDA
D Grint
L Peters
C Schwarze-Zander
M Beniowski
C Pradier
M Battegay
D Jevtovic
V Soriano
JD Lundgren
JK Rockstroh
et al.
A1
Artikel in een tijdschrift
in
HIV MEDICINE
2013
Touchdown digital PCR for quantification of difficult amplicons in the HIV genome
Ward De Spiegelaere
Eva Malatinková
Maja Kiselinova
Pawel Bonczkowski
Chris Verhofstede
Dirk Vogelaers
Linos Vandekerckhove
C3
Conferentie
2013
Touchdown digital polymerase chain reaction for quantification of highly conserved sequences in the HIV-1 genome
Ward De Spiegelaere
Eva Malatinková
Maja Kiselinova
Pawel Bonczkowski
Chris Verhofstede
Dirk Vogelaers
Linos Vandekerckhove
A1
Artikel in een tijdschrift
in
ANALYTICAL BIOCHEMISTRY
2013
2012
A national cohort of HIV-infected patients in Belgium: design and main characteristics
D Van Beckhoven
A Buvé
J Ruelle
L Seyler
A Sasse
the Belgian HIV cohort study group
Dirk Vogelaers
Linos Vandekerckhove
A1
Artikel in een tijdschrift
in
ACTA CLINICA BELGICA
2012
Characterization of LEDGF/p75 genetic variants and association with HIV-1 disease progression
Peter Messiaen
Ward De Spiegelaere
Jose Alcami
Karen Vervisch
Petra Van Acker
Bruno Verhasselt
Pieter Meuwissen
Esther Calonge
Nuria Gonzalez
Felix Gutierrez-Rodero
et al.
A1
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in
PLOS ONE
2012
Co-formulated elvitegravir, cobicistat, emtricitabine, and tenofovir disoproxil fumarate versus ritonavir-boosted atazanavir plus co-formulated emtricitabine and tenofovir disoproxil fumarate for initial treatment of HIV-1 infection: a randomised, double-blind, phase 3, non-inferiority trial
Edwin DeJesus
Jürgen K Rockstroh
Keith Henry
Jean-Michel Molina
Joseph Gathe
Srinivasan Ramanathan
Xuelian Wei
Kitty Yale
Javier Swarcberg
Kirsten White
et al.
A1
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in
LANCET
2012
Comprehensive characterization of LEDGF/p75 in a HIV-1 infected patient cohort
Peter Messiaen
Ward De Spiegelaere
Jose Alcami
Paul Coucke
Petra Van Acker
Karen Vervisch
Bruno Verhasselt
Pieter Meeuwissen
Bruce Poppe
Dirk Vogelaers
et al.
C3
Conferentie
2012
Correlation of coreceptor usage and disease progression
Chris Verhofstede
Monique Nijhuis
Linos Vandekerckhove
A1
Artikel in een tijdschrift
in
CURRENT OPINION IN HIV AND AIDS
2012
Hepatitis C virus viremia increases the incidence of chronic kidney disease in HIV-infected patients
Lars Peters
Daniel Grint
Jens D Lundgren
Jürgen K Rockstroh
Vincent Soriano
Peter Reiss
Anna Grzeszczuk
Helen Sambatakou
Amanda Mocroft
Ole Kirk
et al.
A1
Artikel in een tijdschrift
in
AIDS
2012
Heterogeneity in outcomes of treated HIV-positive patients in Europe and North America: relation with patient and cohort characteristics
Margaret T May
Robert S Hogg
Amy C Justice
Bryan E Shepherd
Dominique Costagliola
Bruno Ledergerber
Rodolphe Thiébaut
M John Gill
Ole Kirk
Ard van Sighem
et al.
A1
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in
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
2012
Impact of triplicate testing on HIV genotypic tropism prediction in routine clinical practice
J Symons
Linos Vandekerckhove
R Paredes
Chris Verhofstede
R Bellido
Els Demecheleer
PM van Ham
SFL van Lelyveld
AJ Stam
D van Versendaal
et al.
A1
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in
CLINICAL MICROBIOLOGY AND INFECTION
2012
Predicting the short-term risk of diabetes in HIV-positive patients: the Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) study
Kathy Petoumenos
Signe W Worm
Eric Fontas
Rainer Weber
Stephane De Wit
Mathias Bruyand
Peter Reiss
Wafaa El-Sadr
Antonella D'Arminio Monforte
Nina Friss-Moller
et al.
A1
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in
JOURNAL OF THE INTERNATIONAL AIDS SOCIETY
2012
Presence of CXCR4-using HIV-1 in patients with recently diagnosed infection: correlates and evidence for transmission
Kristen Chalmet
Kenny Dauwe
Lander Foquet
Franky Baatz
Carole Seguin-Devaux
Beatrijs Van Der Gucht
Dirk Vogelaers
Linos Vandekerckhove
Jean Plum
Chris Verhofstede
A1
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in
JOURNAL OF INFECTIOUS DISEASES
2012
Regional differences in AIDS and non-AIDS related mortality in HIV-positive individuals across Europe and Argentina : the EuroSIDA study
Joanne Reekie
Justyna D Kowalska
Igor Karpov
Jurgen Rockstroh
Anders Karlsson
Aza Rakhmanova
Andrzej Horban
Ole Kirk
Jens D Lundgren
Amanda Mocroft
et al.
A1
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in
PLOS ONE
2012
The clinical benefits of antiretroviral therapy in severely immunocompromised HIV-1-infected patients with and without complete viral suppression
Amanda Mocroft
Wendy P Bannister
Ole Kirk
Jystyna D Kowalska
Peter Reiss
Antonella D'Arminio-Monforte
Jose Gatell
Martin Fisher
Hanna Trocha
Aza Rakhmanova
et al.
A1
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in
ANTIVIRAL THERAPY
2012
The cure of the 'Berlin patient': why did pre-existing X4-variants not emergence after allogeneic CCR5-Delta 32 SCT?
J Symons
S Deeks
G Hutter
A Wensing
J Martin
P van Ham
Linos Vandekerckhove
M Nijhuis
C3
Conferentie
2012
Ultra-deep sequencing of HIV-1 reverse transcriptase before start of an NNRTI-based regimen in treatment-naive patients
Peter Messiaen
Chris Verhofstede
Ina Vandenbroucke
Sylvie Dinakis
Veerle Van Eygen
Kim Thys
Bart Winters
Jeroen Aerssens
Dirk Vogelaers
Lieven J Stuyver
et al.
A1
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VIROLOGY
2012
2011
A comparison of the long-term durability of nevirapine, efavirenz and lopinavir in routine clinical practice in Europe: a EuroSIDA study
J Reekie
P Reiss
B Ledergerber
D Sedlacek
M Parczewski
J Gatell
C Katlama
G Fätkenheuer
JD Lundgren
A Mocroft
et al.
A1
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in
HIV MEDICINE
2011
A standardized algorithm for determining the underlying cause of death in HIV infection as AIDS or non-AIDS related: results from the EuroSIDA study
Justyna D Kowalska
Amanda Mocroft
Bruno Dergerber
Eric Florence
Matti Ristola
Josip Begovac
Helen Sambatakou
Court Pedersen
Jens D Lundgren
Ole Kirk
et al.
A1
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in
HIV CLINICAL TRIALS
2011
A376S in the connection subdomain of HIV-1 reverse transcriptase confers increased risk of virological failure to nevirapine therapy
Roger Paredes
Maria Carmen Puertas
Wendy Bannister
Mónica Kisic
Alessandro Cozzi-lepri
Christian Pou
Rocío Bellido
Gilberto Betancor
Johannes Bogner
Panagiotis Gargalianos
et al.
A1
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in
JOURNAL OF INFECTIOUS DISEASES
2011
Comparison of phenotypic and genotypic tropism determination in triple-class-experienced HIV patients eligible for maraviroc treatment
Linos Vandekerckhove
Chris Verhofstede
Els Demecheleer
Stephane De Wit
Eric Florence
Katrien Fransen
Michel Moutschen
Wendy Mostmans
Kabamba Kabeya
Nicola Mackie
et al.
A1
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in
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
2011
Comprehensive characterization of LEDGF/p75 in a HIV-1-infected patient cohort
Peter Messiaen
Ward De Spiegelaere
Chris Verhofstede
Paul Coucke
Petra Van Acker
Philip Vlummens
KAREN VERVISCH
Dirk Vogelaers
Bruce Poppe
Jose Alcami
et al.
C3
Conferentie
2011
Concordance between HIV-1 genotypic coreceptor tropism predictions based on plasma RNA and proviral DNA
Chris Verhofstede
D Brudney
Jacqueline Reynaerts
D Vaira
K Fransen
A De Bel
C Seguin-Devaux
S De Wit
Linos Vandekerckhove
A-M Geretti
A1
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HIV MEDICINE
2011
Estimating prevalence of accumulated HIV-1 drug resistance in a cohort of patients on antiretroviral therapy
Wendy P Bannister
Alessandro Cozzi-Lepri
Jesper Kjær
Clotet Bonaventura
Adriano Lazzarin
Jean-Paul Viard
Gitte Kronberg
Dan Duiculescu
Marek Beniowsk
Ladislav Machala
et al.
A1
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in
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
2011
European guidelines on the clinical management of HIV-1 tropism testing
Linos Vandekerckhove
AMJ Wensing
R Kaiser
F Brun-Vézinet
B Clotet
A De Luca
S Dressler
F Garcia
AM Geretti
T Klimkait
et al.
A1
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in
LANCET INFECTIOUS DISEASES
2011
Fatal and nonfatal AIDS and non-AIDS events in HIV-1-positive individuals with high CD4 cell counts according to viral load strata
Joanne Reekie
Jose M Gatell
Israel Yust
Elzbieta Bakowska
Aza Rakhmanova
Marcelo Losso
Maksym Krasnov
Patrick Francioli
Justyna D Kowalska
Amanda Mocroft
et al.
A1
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AIDS
2011
Selection of the raltegravir resistance pathway is affected by the HIV-1 population size
A Fun
Linos Vandekerckhove
M Däumer
A Thielen
B Buchholz
LJ Maarschalk-Ellerbroek
PJ Schipper
AMJ Wensing
M Nijhuis
C3
Conferentie
2011
Tuberculosis among HIV-positive patients across Europe: changes over time and risk factors
Alexey Kruk
Wendy Bannister
Daria N Podlekareva
Nelly P Chentsova
Aza G Rakhmanova
Andrzej Horban
Perre Domingo
Amanda Mocroft
Jens D Lundgren
Ole Kirk
et al.
A1
Artikel in een tijdschrift
in
AIDS
2011
Vitamin D and clinical disease progression in HIV infection: results from the EuroSIDA study
Jean-Paul Viard
Jean-Claude Souberbielle
Ole Kirk
Joanne Reekie
Brygida Knysz
Marcelo Losso
Jose Gatell
Court Pedersen
Johannes R Bogner
Jens D Lundgren
et al.
A1
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AIDS
2011
2010
An adjuvanted protein HIV vaccine induces polyfunctional CD4 T-cell responses in healthy volunteers similar to those in HIV-infected viral controllers
Eva Van Braeckel
Frédéric Clement
Linos Vandekerckhove
Dirk Vogelaers
Geert Leroux-Roels
C3
Conferentie
2010
An adjuvanted protein HIV vaccine induces polyfunctional CD4(+) T-cell responses in healthy volunteers similar to those in HIV-infected viral controllers
Eva Van Braeckel
Frédéric Clement
Linos Vandekerckhove
Dirk Vogelaers
Geert Leroux-Roels
C3
Conferentie
2010
Dialysis and renal transplantation in HIV-infected patients: a European survey
Joan Carles Trullas
Amanda Mocroft
Federico Cofan
Jérome Tourret
Asunción Moreno
Corinne Isnard Bagnis
Christoph Andreas Fux
Christine Katlama
Peter Reiss
Jens Lundgren
et al.
A1
Artikel in een tijdschrift
in
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
2010
Effect of triplicate testing on genotypic tropism prediction in routine clinical practice
J Symons
Linos Vandekerckhove
R Paredes
Chris Verhofstede
R Bellido
Els Demecheleer
Paulyn Van Hamme
SFL van Lelyveld
AL Stam
D van Versendaal
et al.
C3
Conferentie
2010
Epidemiological study of phylogenetic transmission clusters in a local HIV-1 epidemic reveals distinct differences between subtype B and non-B infections
Kristen Chalmet
Delfien Staelens
Stijn Blot
Sylvie Dinakis
Jolanda Pelgrom
Jean Plum
Dirk Vogelaers
Linos Vandekerckhove
Chris Verhofstede
A1
Artikel in een tijdschrift
in
BMC INFECTIOUS DISEASES
2010
Estimated glomerular filtration rate, chronic kidney disease and antiretroviral drug use in HIV-positive patients
Amanda Mocroft
Ole Kirk
Peter Reiss
Stephane De Wit
Dalibor Sedlacek
Marek Beniowski
Jose Gatell
Andrew N Phillips
Bruno Ledergerber
Jens D Lundgren
et al.
A1
Artikel in een tijdschrift
in
AIDS
2010
GSK-1349572, a novel integrase inhibitor for the treatment of HIV infection
Linos Vandekerckhove
A1
Artikel in een tijdschrift
in
CURRENT OPINION IN INVESTIGATIONAL DRUGS
2010
HIV-1 V3 envelope deep sequencing for clinical plasma specimens failing in phenotypic tropism assays
Ina Vandenbroucke
Herwig Van Marck
Wendy Mostmans
Veerle Van Eygen
Evelien Rondelez
Kim Thys
Kurt Van Baelen
Katrien Fransen
Dolores Vaira
Kabamba Kabeya
et al.
A1
Artikel in een tijdschrift
in
AIDS RESEARCH AND THERAPY
2010
High prevalence of bevirimat resistance mutations in protease inhibitor-resistant HIV isolates
Jens Verheyen
Chris Verhofstede
Elena Knops
Linos Vandekerckhove
Axel Fun
Diede Brunen
Kenny Dauwe
Annemarie MJ Wensing
Herbert Pfister
Rolf Kaiser
et al.
A1
Artikel in een tijdschrift
in
AIDS
2010
High prevalence of the metabolic syndrome in HIV-infected patients: impact of different definitions of the metabolic syndrome
Signe W Worm
Nina Friss-Møller
Mathias Bruyand
Antonella D'Arminio Monforte
Martin Rickenbach
Peter Reiss
Wafaa El-Sadr
Andrew Philips
Jens Lundgren
Caroline Sabin
et al.
A1
Artikel in een tijdschrift
in
AIDS
2010
History of viral suppression on combination antiretroviral therapy as a predictor of virological failure after a treatment change
J Reekie
A Mocroft
B Ledergerber
M Beniowski
B Clotet
J Van Lunzen
A Chiesi
C Pradier
L Machale
JD Lundgren
et al.
A1
Artikel in een tijdschrift
in
HIV MEDICINE
2010
Impaired hemoglobin scavenging during an acute HIV-1 retroviral syndrome
Joris Delanghe
Jan Philippé
FILIP MOERMAN
Marc De Buyzere
Liesbeth L Vynckier
Alain Verstraete
Dirk Vogelaers
Linos Vandekerckhove
A1
Artikel in een tijdschrift
in
CLINICA CHIMICA ACTA
2010
Invasive infection with Rhodococcus equi : two case reports and review of literature
VINCIANE GUYSSENS
Linos Vandekerckhove
Isabelle Colle
P De Rudder
Stijn Blot
Dirk Vogelaers
A1
Artikel in een tijdschrift
in
ACTA CLINICA BELGICA
2010
Morbidity and mortality of bloodstream infections in patients with severe burn injury
Nele Brusselaers
Stan Monstrey
Thomas Snoeij
Dominique Vandijck
CHRISTELLE LIZY
Eric Hoste
STEFAAN LAUWAERT
Kirsten Colpaert
Linos Vandekerckhove
Dirk Vogelaers
et al.
A1
Artikel in een tijdschrift
in
AMERICAN JOURNAL OF CRITICAL CARE
2010
O121. Consensus statement of the European guidelines on clinical management of HIV-1 tropism testing
Linos Vandekerckhove
AMJ Wensing
R Kaiser
F Brun-Vezinet
B Clotet
A De Luca
S Dressler
F Garcia
AM Geretti
T Klimkait
et al.
C3
Conferentie
2010
Predicting the risk of cardiovascular disease in HIV-infected patients: the Data collection on Adverse Effects of Anti-HIV Drugs Study
Nina Friis-Møller
Rodolphe Thiébaut
Peter Reiss
Rainer Weber
Antonella D'Arminio Monforte
Stephane De Wit
Wafaa El-Sadr
Eric Fontas
Signe Worm
Ole Kirk
et al.
A1
Artikel in een tijdschrift
in
EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION & REHABILITATION
2010
Predictors of hepatitis B virus genotype and viraemia in HIV-infected patients with chronic hepatitis B in Europe
Victor Soriano
Amanda Mocroft
Lars Peters
Jürgen Rockstroh
Francisco Antunes
Nikolai Kirkby
Stephane De Wit
Antonella d'Arminio Monforte
Robert Flisiak
Jens Lundgren
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
2010
Serious fatal and nonfatal non-AIDS-defining illnesses in Europe
Amanda Mocroft
Peter Reiss
Jacek Gasiorowski
Bruno Ledergerber
Justyna Kowalska
Antonio Chiesi
Jose Gatell
Aza Rakhmanova
Margaret Johnson
Ole Kirk
et al.
A1
Artikel in een tijdschrift
in
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
2010
Severe drug-induced liver injury associated with prolonged use of Linezolid
Liesbet De Bus
Pieter Depuydt
Louis Libbrecht
Linos Vandekerckhove
JOKE NOLLET
Dominique Benoit
Dirk Vogelaers
Hans Van Vlierberghe
A2
Artikel in een tijdschrift
in
JOURNAL OF MEDICAL TOXICOLOGY
2010
2009
CXCR4-using HIV type 1 variants are more commonly found in peripheral blood mononuclear cell DNA than in plasma RNA
Chris Verhofstede
Linos Vandekerckhove
Veerle Van Eygen
Els Demecheleer
Ina Vandenbroucke
Bart Winters
Jean Plum
Dirk Vogelaers
Lieven Stuyver
A1
Artikel in een tijdschrift
in
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
2009
Comparison of population and 454 genotyping and Trofile phenotyping for tropism determination in patients selected for maraviroc initiation
Linos Vandekerckhove
Chris Verhofstede
I Vandenbroucke
C Booth
H Van Marck
AM Geretti
L Stuyver
C3
Conferentie
2009
Evaluation of antibiotic dosages in patients with reduced kidney function
Franky Buyle
Tine Verdonck
Dirk Vogelaers
Johan Decruyenaere
Linos Vandekerckhove
TOM FIERS
Annemieke Dhondt
Hugo Robays
C3
Conferentie
2009
High prevalence of bevirimat resistance mutations in non-B subtypes and in PI-resistant HIV isolates
J Verheyen
Chris Verhofstede
E Knops
Linos Vandekerckhove
A Fun
D Brunen
Kenny Dauwe
A Wensing
H Pfister
R Kaiser
et al.
C3
Conferentie
2009
Maraviroc: perspectives for use in antiretroviral-naive HIV-1-infected patients
Linos Vandekerckhove
Chris Verhofstede
Dirk Vogelaers
A1
Artikel in een tijdschrift
in
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
2009
Outcome and resources use of severe burn injury patients with nosocomial bloodstream infection : results of a matched cohort study
Nele Brusselaers
Stan Monstrey
Eric Hoste
CHRISTELLE LIZY
Dominique Vandijck
Linos Vandekerckhove
Lieven Annemans
Dirk Vogelaers
Stijn Blot
C3
Conferentie
2009
Population and clonal tropism phenotyping of clinical isolates and comparison with next generation sequencing and prediction tools
K Van Baelen
E Rondelez
L Van Wesenbeeck
W Mostmans
H Van Marck
V Van Eygen
Chris Verhofstede
Linos Vandekerckhove
I Vandenbroucke
L Stuyver
C3
Conferentie
2009
Risk factors for treatment-limiting toxicities in patients starting nevirapine-containing antiretroviral therapy
Anouk M Kesselring
Ferndinand W Wit
Caroline A Sabin
Jens D Lundgren
M John Gill
Jose M Gatell
Andri Rauch
Julio S Montaner
Frank De Wolf
Peter Reiss
et al.
A1
Artikel in een tijdschrift
in
AIDS
2009
2008
Abacavir hypersensitivity
Linos Vandekerckhove
Stijn Blot
Dirk Vogelaers
A1
Artikel in een tijdschrift
in
NEW ENGLAND JOURNAL OF MEDICINE
2008
Fluconazole exposure and selection for Candida non-albicans
Dominique Vandijck
Stijn Blot
Linos Vandekerckhove
Dirk Vogelaers
A1
Artikel in een tijdschrift
in
ANESTHESIA AND ANALGESIA
2008
Impact of Delta 32-CCR5 heterozygosity on HIV-1 genetic evolution and variability - A study of 4 individuals infected with closely related HIV-1 strains
Kristen Chalmet
Filip Van Wanzeele
Els Demecheleer
Kenny Dauwe
Jolanda Pelgrom
Beatrijs Van Der Gucht
Dirk Vogelaers
Jean Plum
Lieven Stuyver
Linos Vandekerckhove
et al.
A1
Artikel in een tijdschrift
in
Virology
2008
Maraviroc: integration of a new antiretroviral drug class into clinical practice
Linos Vandekerckhove
Chris Verhofstede
Dirk Vogelaers
A1
Artikel in een tijdschrift
in
Journal of Antimicrobial Chemotherapy
2008
Resistance pathway analysis of diketo acid-based integrase inhibitors allows mapping and prediction of chemical properties of integrase inhibitors
A Voet
F Christ
M De Maeyer
Z Debyser
Linos Vandekerckhove
C3
Conferentie
2008
2007
Detection of drug resistance mutations as a predictor of subsequent virological failure in patients with HIV-1 viral rebounds of less than 1,000 RNA copies/ml
Chris Verhofstede
Filip Van Wanzeele
Beatrijs Van Der Gucht
Jolanda Pelgrom
Linos Vandekerckhove
Jean Plum
Dirk Vogelaers
A1
Artikel in een tijdschrift
in
JOURNAL OF MEDICAL VIROLOGY
2007
Lentiviral nuclear import: a complex interplay between virus and host
Jan De rijck
Linos Vandekerckhove
Frauke Christ
Zeger Debyser
A1
Artikel in een tijdschrift
in
BIOESSAYS
2007
Virus evolution reveals an exclusive role for LEDGF/p75 in chromosomal tethering of HIV
Anneleen Hombrouck
Jan De Rijck
Jelle Hendrix
Linos Vandekerckhove
Arnout Voet
Marc De Maeyer
Myriam Witvrouw
Yves Engelborghs
Frauke Christ
Rik Gijsbers
et al.
A1
Artikel in een tijdschrift
in
PLOS PATHOGENS
2007
2006
Cellular co-factors of HIV-1 integration
Bénédicte Van Maele
Katrien Busschots
Linos Vandekerckhove
Frauke Christ
Zeger Debyser
A1
Artikel in een tijdschrift
in
TRENDS IN BIOCHEMICAL SCIENCES
2006
Overexpression of the lens epithelium-derived growth factor/p75 integrase binding domain inhibits human immunodeficiency virus replication
Jan De Rijck
Linos Vandekerckhove
Rik Gijsbers
Anneleen Hombrouck
Jelle Hendrix
Jo Vercammen
Yves Engelborghs
Frauke Christ
Zeger Debyser
A1
Artikel in een tijdschrift
in
JOURNAL OF VIROLOGY
2006
Transient and stable knockdown of the integrase cofactor LEDGF/p75 reveals its role in the replication cycle of human immunodeficiency virus
Linos Vandekerckhove
Frauke Christ
Bénédicte Van Maele
Jan De Rijck
Rik Gijsbers
Chris Van den Haute
Myriam Witvrouw
Zeger Debyser
A1
Artikel in een tijdschrift
in
JOURNAL OF VIROLOGY
2006
2005
Integrase mutants defective for interaction with LEDGF/p75 are impaired in chromosome tethering and HIV-1 replication
Stéphane Emiliani
Aurélie Mousnier
Katrien Busschots
Marlène Maroun
Bénédicte Van Maele
Denis Tempe
Linos Vandekerckhove
Fanny Moisant
Lilia Ben-Slama
Myriam Witvrouw
et al.
A1
Artikel in een tijdschrift
in
JOURNAL OF BIOLOGICAL CHEMISTRY
2005