Research Explorer

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Lies Vantomme

Prijzen & Erkenningen

50 Resultaten

2025

Non-coding structural variants identify a commonly affected regulatory region steering FOXG1 transcription in early neurodevelopment

Lisa HamerlinckEva D'haeneNore Van LoonMichael B VaughanMaria del Rocio Pérez BacaSebastian LeimbacherLara ColomboLies VantommeEsperanza DaalAnnelies Dheedene et al.

2024

Clinical impact of RNA-sequencing in diagnostics

Laurenz De CockErika D'haenensSarah VergultLies VantommeAnnelies DheedeneRobin de PutterTim Van DammeJo SourbronBert CallewaertOlivier Vanakker et al.

Comparative 3D genome analysis between neural retina and retinal pigment epithelium reveals differential cis-regulatory interactions at retinal disease loci

Eva D'haeneVictor Lopez SorianoPedro Manuel Martínez-GarcíaSoraya KalayanamontriAlfredo Dueñas ReyAna Sousa-OrtegaSilvia NaranjoStijn Van de SompeleLies VantommeQuinten Mahieu et al.

A1 Artikel in een tijdschrift in GENOME BIOLOGY

Full characterization of unresolved structural variation through long-read sequencing and optical genome mapping

Griet De ClercqLies VantommeBarbara DewaeleBert CallewaertOlivier VanakkerSandra JanssensBart LoeysMojca StrazisarWouter De CosterJoris Robert Vermeesch et al.

A1 Artikel in een tijdschrift in SCIENTIFIC REPORTS

Haploinsufficiency of ZFHX3, encoding a key player in neuronal development, causes syndromic intellectual disability

Maria del Rocio Pérez BacaEva JacobsLies VantommePontus LeBlancElke BogaertAnnelies DheedeneLaurenz De CockSadegheh HaghshenasAidin ForoutanMichael A Levy et al.

A1 Artikel in een tijdschrift in AMERICAN JOURNAL OF HUMAN GENETICS

Loss-of-function of the Zinc Finger Homeobox 4 (ZFHX4) gene causes a novel neurodevelopmental disorder

Maria del Rocio Pérez BacaMaria PalomaresMichiel VanhooydonckEva D'haeneEva Z. JacobsLies VantommeFernando Santos-SimarroRoser Lleuger-PujolSixto García-MiñaúrItsaso Losantos-García et al.

Loss-of-function of the Zinc Finger Homeobox 4 (ZFHX4) gene causes a novel neurodevelopmental disorder

Maria del Rocio Pérez BacaMaria PalomaresMichiel VanhooydonckEva D'haeneEva JacobsLies VantommeFernando Santos-SimarroRoser Lleuger-PujolSixto García-MiñáurItsaso Losantos-García et al.

Loss-of-function of the Zinc Finger Homeobox 4 (ZFHX4) gene underlies a neurodevelopmental disorder

Maria del Rocio Pérez BacaMaria Palomares BraloMichiel VanhooydonckLisa HamerlinckEva D'haeneSebastian LeimbacherEva JacobsLaurenz De CockErika D'haenensZoë Malfait et al.

Loss-of-function of the Zinc Finger Homeobox 4 (ZFHX4) gene underlies a neurodevelopmental disorder

Maria del Rocio Pérez BacaMaría Palomares BraloMichiel VanhooydonckLisa HamerlinckEva D'haeneSebastian LeimbacherEva JacobsLaurenz De CockErika D'haenensAnnelies Dheedene et al.

Neoantigen-targeted dendritic cell vaccination in lung cancer patients induces long-lived T cells exhibiting the full differentiation spectrum

Joline IngelsLaurenz De CockDieter StevensRupert MayerFabien Henri TheryGuillem Sanchez SanchezDavid VermijlenKarin WeeningSaskia De SmetNele Lootens et al.

A1 Artikel in een tijdschrift in CELL REPORTS MEDICINE

Structural variants disrupt a critical regulatory region downstream of FOXG1

Lisa HamerlinckEva D'haeneNore Van LoonMaria del Rocio Pérez BacaSarah VergultBert CallewaertElfride De BaereBjörn MentenLies VantommeMichael B Vaughan

2023

An optimized workflow for CRISPR/Cas9-mediated generation of indels and large deletions in induced pluripotent stem cells and neural stem cells

Lisa HamerlinckMaria del Rocio Pérez BacaLies VantommeEva D'haeneSarah Vergult

Comparative 3D genome analysis between neural retina and RPE reveals diferential cis-regulatory interactions at retinal disease loci

Eva D'haeneVictor Lopez SorianoPedro Manuel Martinez-GarciaSoraya KalayanamontriAlfredo Dueñas ReyAna Sousa-OrtegaSilvia NaranjoStijn Van de SompeleLies VantommeQuinten Mahieu et al.

Comparative 3D genome analysis between neural retina and RPE reveals differential cis-regulatory interactions at retinal disease loci

Eva D'haenePedro Manuel Martinez-GarciaVictor Lopez SorianoSoraya KalayanamontriAlfredo Dueñas ReyLies VantommeSarah VergultAna Bastos NetoJosé Luis Gomez-SkarmetaJuan Ramon Martinez-Morales et al.

Comparative 3D genome analysis between neural retina and RPE reveals differential cis-regulatory interactions at retinal disease loci

Eva D'haeneVictor Lopez SorianoPedro Manuel Martínez-GarcíaSoraya KalayanamontriAlfredo Dueñas ReyAna Sousa-OrtegaSilvia NaranjoStijn Van de SompeleLies VantommeQuinten Mahieu et al.

Differential 3D genome topology shapes the regulatory landscapes of IRD genes in human neural retina and retinal pigment epithelium

Eva D'haenePedro Martinez-GarciaVictor Lopez SorianoMiriam BauwensLies VantommeSarah VergultJuan Martinez-MoralesJuan TenaElfride De Baere

Long-read sequencing and optical genome mapping enable full characterization of previously unresolved structural variation

Griet De ClercqLies VantommeBert CallewaertSarah VergultWouter De CosterMojca StrazisarTim De PooterBarbara DewaeleJoris VermeeschAnnelies Dheedene et al.

Long-read sequencing and optical genome mapping enable full characterization of previously unresolved structural variation

Griet De ClercqLies VantommeBert CallewaertBarbara DewaeleJoris VermeeschAnnelies DheedeneBjörn Menten

Long-read sequencing enables full characterization of previously unresolved structural variation

Griet De ClercqLies VantommeBert CallewaertAnnelies DheedeneBjörn Menten

Long-read sequencing resolves (complex) cryptic structural variation in patients with syndromic intellectual disability

Griet De ClercqLies VantommeBert CallewaertSarah VergultAnnelies DheedeneBjörn Menten

Long-read sequencing resolves (complex) cryptic structural variation in patients with syndromic intellectual disability

Griet De ClercqLies VantommeBert CallewaertSarah VergultAnnelies DheedeneBjörn Menten

Long-read sequencing resolves (complex) cryptic structural variation in patients with syndromic intellectual disability

Griet De ClercqLies VantommeBert CallewaertSarah VergultAnnelies DheedeneBjörn Menten

Mapping the 3D genome of the human retina and its role in retinal disease

Eva D'haeneVictor Lopez SorianoLies VantommeBernd WissingerSusanne KohlSarah VergultElfride De Baere

Structural variants disrupt a critical regulatory region downstream of FOXG1

Lisa HamerlinckEva D'haeneMichael B VaughanMaria del Rocio Pérez BacaNore Van LoonLies VantommeBjörn MentenBert CallewaertElfride De BaereSarah Vergult

Structural variants disrupt a critical regulatory region downstream of FOXG1

Lisa HamerlinckEva D'haeneSarah VergultNore Van LoonMaria del Rocio Pérez BacaLies VantommeMichael B VaughanElfride De BaereBert CallewaertBjörn Menten

Structural variants disrupt a critical regulatory region downstream of FOXG1

Eva D'haeneLies VantommeBjörn MentenBert CallewaertElfride De BaereSarah Vergult

Structural variants disrupt a critical regulatory region downstream of FOXG1

Lisa HamerlinckEva D'haeneMaria del Rocio Pérez BacaLies VantommeNore Van LoonBjörn MentenBert CallewaertElfride De BaereSarah Vergult

2022

A novel neurodevelopmental syndrome caused by loss-of-function of the Zinc Finger Homeobox 3 (ZFHX3) gene

Maria del Rocio Pérez BacaEva JacobsLies VantommePontus LeBlancElke BogaertAnnelies DheedeneLaurenz De CockBart DermautAidin ForoutanJennifer Kerkhof et al.

An optimized workflow for CRISPR/Cas9-mediated generation of indels and large deletions in induced pluripotent stem cells and neural stem cells

Lisa HamerlinckMaria del Rocio Pérez BacaLies VantommeEva D'haeneSarah Vergult

Benchmarking of long read structural variant callers using Oxford Nanopore data

Griet De ClercqBram Van GaeverLies VantommeAnnelies DheedeneBjörn Menten

Benchmarking of long-read structural variant callers using Oxford Nanopore data

Griet De ClercqBram Van GaeverLies VantommeAnnelies DheedeneBjörn Menten

Benchmarking of long-read structural variant callers using Oxford Nanopore data

Griet De ClercqBram Van GaeverLies VantommeAnnelies DheedeneBjörn Menten

Benchmarking of long-read structural variant callers using in-house generated Oxford Nanopore data

Griet De ClercqBram Van GaeverLies VantommeAnnelies DheedeneBjörn Menten

Long-read sequencing resolves cryptic structural variation in patients with syndromic intellectual disability

Griet De ClercqLies VantommeBert CallewaertSarah VergultAnnelies DheedeneBjörn Menten

Mapping the 3D genome of the human retina and its role in retinal disease

Eva D'haeneVictor Lopez SorianoLies VantommeBernd WissingerSusanne KohlSarah VergultElfride De Baere

Regulatory landscaping : towards improved genetic diagnosis and therapy for SATB2-associated syndrome

Lisa HamerlinckLies VantommeEva D'haeneSarah VergultBert Callewaert

2021

A novel neurodevelopmental syndrome caused by loss-of-function of the Zinc Finger Homeobox 3 gene (ZFHX3)

Maria del Rocio Pérez BacaEva JacobsLies VantommeMareike BauerMelissa BelliniClaire BeneteauNatasha BrownDavid ComanLaurenz De CockAnnelies Dheedene et al.

Benchmarking of long-read structural variant callers on a recently released truth set using Oxford Nanopore data

Griet De ClercqBram Van GaeverLies VantommeAnnelies DheedeneBjörn Menten

Benchmarking of long-read structural variant callers on a recently released truth set using Oxford Nanopore data

Griet De ClercqBram Van GaeverLies VantommeAnnelies DheedeneBjörn Menten

Structural variants disrupt a critical regulatory region downstream of FOXG1

Eva D'haeneLies VantommeBjörn MentenBert CallewaertElfride De BaereSarah Vergult

2019

A neuronal enhancer network upstream of MEF2C is compromised in patients with Rett-like characteristics

Eva D'haeneReut Bar-YaacovInbar BariahLies VantommeSien Van LooFrancisco Avila CobosKaren VerboomReut EshelRawan AlatawnaBjörn Menten et al.

A1 Artikel in een tijdschrift in HUMAN MOLECULAR GENETICS

Noncoding structural variants disrupt the regulatory architecture of Rett genes

Eva D'haeneReut Bar-YaacovInbar BariahLies VantommeSien Van LooFrancisco Avila CobosKaren VerboomReut EshelRawan AlatawnaBjörn Menten et al.

Noncoding structural variants disrupt the regulatory architecture of Rett genes

Eva D'haeneReut Bar-YaacovInbar BariahLies VantommeSien Van LooFrancisco Avila CobosKaren VerboomReut EshelRawan AlatawnaBjörn Menten et al.

2018

A neuronal enhancer network upstream of MEF2C is compromised in patients with Rett-like characteristics

Eva D'haeneReut Bar-YaacovInbar BariahLies VantommeSien Van LooFrancisco Avila CobosKaren VerboomReut EshelRawan AlatawnaBjörn Menten et al.

CRISPR/Cas9-mediated genome editing in naïve human embryonic stem cells

Eva JacobsSharat WarrierPieter-Jan VoldersEva D'haeneEva VanlombergenLies VantommeMargot Van der JeughtBjörn HeindryckxBjörn MentenSarah Vergult

CRISPR/Cas9-mediated genome editing in naïve human embryonic stem cells

Eva JacobsSharat WarrierPieter-Jan VoldersEva D'haeneEva VanlombergenLies VantommeMargot Van der JeughtBjörn HeindryckxBjörn MentenSarah Vergult

The MEF2C regulatory network is disrupted in patients with Rett-like characteristics

Eva D'haeneSarah VergultReut Bar-YaakovInbar BariahLies VantommeSien Van LooFrancisco Avila CobosReut EshelRowan AlatawnaRamon Birnbaum et al.

The MEF2C regulatory network is disrupted in patients with Rett-like characteristics

Eva D'haeneReut Bar-YaakovInbar BariahSien Van LooLies VantommeFrancisco Avila CobosReut EshelRowan AlatawnaBjörn MentenRamon Birnbaum et al.

2017

CRISPR/Cas9-mediated genome editing in naïve human embryonic stem cells

Eva JacobsSharat WarrierPieter-Jan VoldersEva D'haeneEva Van LombergenLies VantommeMargot Van der JeughtBjörn HeindryckxBjörn MentenSarah Vergult

A1 Artikel in een tijdschrift in SCIENTIFIC REPORTS

2015

Two siblings with homozygous pathogenic splice-site variant in mitochondrial asparaginyl-tRNA synthetase (NARS2)

Arnaud VanlanderBjörn MentenJoél SmetLinda De MeirleirTom SanteBoel De PaepeSara SenecaSarah F PearceChristopher A PowellSarah Vergult et al.

A1 Artikel in een tijdschrift in HUMAN MUTATION