Manage settings
MENU
About this site
In het Nederlands
Home
Researchers
Projects
Organisations
Publications
Infrastructure
Contact
Research Explorer
Your browser does not support JavaScript or JavaScript is not enabled. Without JavaScript some functions of this webapplication may be disabled or cause error messages. To enable JavaScript, please consult the manual of your browser or contact your system administrator.
Researcher
Lies Vantomme
Profile
Projects
Publications
Activities
Awards & Distinctions
47
Results
2024
Clinical impact of RNA-sequencing in diagnostics
Laurenz De Cock
Erika D'haenens
Sarah Vergult
Lies Vantomme
Annelies Dheedene
Robin de Putter
Tim Van Damme
Jo Sourbron
Bert Callewaert
Olivier Vanakker
et al.
U
Conference
2024
Comparative 3D genome analysis between neural retina and retinal pigment epithelium reveals differential cis-regulatory interactions at retinal disease loci
Eva D'haene
Victor Lopez Soriano
Pedro Manuel Martínez-García
Soraya Kalayanamontri
Alfredo Dueñas Rey
Ana Sousa-Ortega
Silvia Naranjo
Stijn Van de Sompele
Lies Vantomme
Quinten Mahieu
et al.
A1
Journal Article
in
GENOME BIOLOGY
2024
Haploinsufficiency of ZFHX3, encoding a key player in neuronal development, causes syndromic intellectual disability
Maria del Rocio Pérez Baca
Eva Jacobs
Lies Vantomme
Pontus LeBlanc
Elke Bogaert
Annelies Dheedene
Laurenz De Cock
Sadegheh Haghshenas
Aidin Foroutan
Michael A Levy
et al.
A1
Journal Article
in
AMERICAN JOURNAL OF HUMAN GENETICS
2024
Loss-of-function of the Zinc Finger Homeobox 4 (ZFHX4) gene causes a novel neurodevelopmental disorder
Maria del Rocio Pérez Baca
Maria Palomares
Michiel Vanhooydonck
Eva D'haene
Eva Z. Jacobs
Lies Vantomme
Fernando Santos-Simarro
Roser Lleuger-Pujol
Sixto García-Miñaúr
Itsaso Losantos-García
et al.
C3
Conference
2024
Loss-of-function of the Zinc Finger Homeobox 4 (ZFHX4) gene causes a novel neurodevelopmental disorder
Maria del Rocio Pérez Baca
Maria Palomares
Michiel Vanhooydonck
Eva D'haene
Eva Jacobs
Lies Vantomme
Fernando Santos-Simarro
Roser Lleuger-Pujol
Sixto García-Miñáur
Itsaso Losantos-García
et al.
C3
Conference
2024
Loss-of-function of the Zinc Finger Homeobox 4 (ZFHX4) gene underlies a neurodevelopmental disorder
Maria del Rocio Pérez Baca
María Palomares Bralo
Michiel Vanhooydonck
Lisa Hamerlinck
Eva D'haene
Sebastian Leimbacher
Eva Jacobs
Laurenz De Cock
Erika D'haenens
Annelies Dheedene
et al.
Preprint
2024
Neoantigen-targeted dendritic cell vaccination in lung cancer patients induces long-lived T cells exhibiting the full differentiation spectrum
Joline Ingels
Laurenz De Cock
Dieter Stevens
Rupert Mayer
Fabien Henri Thery
Guillem Sanchez Sanchez
David Vermijlen
Karin Weening
Saskia De Smet
Nele Lootens
et al.
A1
Journal Article
in
CELL REPORTS MEDICINE
2024
Structural variants disrupt a critical regulatory region downstream of FOXG1
Lisa Hamerlinck
Eva D'haene
Nore Van Loon
Maria del Rocio Pérez Baca
Sarah Vergult
Bert Callewaert
Elfride De Baere
Björn Menten
Lies Vantomme
Michael B Vaughan
C3
Conference
2024
2023
An optimized workflow for CRISPR/Cas9-mediated generation of indels and large deletions in induced pluripotent stem cells and neural stem cells
Lisa Hamerlinck
Maria del Rocio Pérez Baca
Lies Vantomme
Eva D'haene
Sarah Vergult
C3
Conference
2023
Comparative 3D genome analysis between neural retina and RPE reveals diferential cis-regulatory interactions at retinal disease loci
Eva D'haene
Victor Lopez Soriano
Pedro Manuel Martinez-Garcia
Soraya Kalayanamontri
Alfredo Dueñas Rey
Ana Sousa-Ortega
Silvia Naranjo
Stijn Van de Sompele
Lies Vantomme
Quinten Mahieu
et al.
C3
Conference
2023
Comparative 3D genome analysis between neural retina and RPE reveals differential cis-regulatory interactions at retinal disease loci
Eva D'haene
Pedro Manuel Martinez-Garcia
Victor Lopez Soriano
Soraya Kalayanamontri
Alfredo Dueñas Rey
Lies Vantomme
Sarah Vergult
Ana Bastos Neto
José Luis Gomez-Skarmeta
Juan Ramon Martinez-Morales
et al.
C3
Conference
2023
Comparative 3D genome analysis between neural retina and RPE reveals differential cis-regulatory interactions at retinal disease loci
Eva D'haene
Victor Lopez Soriano
Pedro Manuel Martínez-García
Soraya Kalayanamontri
Alfredo Dueñas Rey
Ana Sousa-Ortega
Silvia Naranjo
Stijn Van de Sompele
Lies Vantomme
Quinten Mahieu
et al.
Preprint
2023
Differential 3D genome topology shapes the regulatory landscapes of IRD genes in human neural retina and retinal pigment epithelium
Eva D'haene
Pedro Martinez-Garcia
Victor Lopez Soriano
Miriam Bauwens
Lies Vantomme
Sarah Vergult
Juan Martinez-Morales
Juan Tena
Elfride De Baere
C3
Conference
2023
Long-read sequencing and optical genome mapping enable full characterization of previously unresolved structural variation
Griet De Clercq
Lies Vantomme
Bert Callewaert
Sarah Vergult
Wouter De Coster
Mojca Strazisar
Tim De Pooter
Barbara Dewaele
Joris Vermeesch
Annelies Dheedene
et al.
C3
Conference
2023
Long-read sequencing and optical genome mapping enable full characterization of previously unresolved structural variation
Griet De Clercq
Lies Vantomme
Bert Callewaert
Barbara Dewaele
Joris Vermeesch
Annelies Dheedene
Björn Menten
C3
Conference
2023
Long-read sequencing enables full characterization of previously unresolved structural variation
Griet De Clercq
Lies Vantomme
Bert Callewaert
Annelies Dheedene
Björn Menten
C3
Conference
2023
Long-read sequencing resolves (complex) cryptic structural variation in patients with syndromic intellectual disability
Griet De Clercq
Lies Vantomme
Bert Callewaert
Sarah Vergult
Annelies Dheedene
Björn Menten
C3
Conference
2023
Long-read sequencing resolves (complex) cryptic structural variation in patients with syndromic intellectual disability
Griet De Clercq
Lies Vantomme
Bert Callewaert
Sarah Vergult
Annelies Dheedene
Björn Menten
C3
Conference
2023
Long-read sequencing resolves (complex) cryptic structural variation in patients with syndromic intellectual disability
Griet De Clercq
Lies Vantomme
Bert Callewaert
Sarah Vergult
Annelies Dheedene
Björn Menten
C3
Conference
2023
Mapping the 3D genome of the human retina and its role in retinal disease
Eva D'haene
Victor Lopez Soriano
Lies Vantomme
Bernd Wissinger
Susanne Kohl
Sarah Vergult
Elfride De Baere
C3
Conference
2023
Structural variants disrupt a critical regulatory region downstream of FOXG1
Lisa Hamerlinck
Eva D'haene
Michael B Vaughan
Maria del Rocio Pérez Baca
Nore Van Loon
Lies Vantomme
Björn Menten
Bert Callewaert
Elfride De Baere
Sarah Vergult
C3
Conference
2023
Structural variants disrupt a critical regulatory region downstream of FOXG1
Lisa Hamerlinck
Eva D'haene
Sarah Vergult
Nore Van Loon
Maria del Rocio Pérez Baca
Lies Vantomme
Michael B Vaughan
Elfride De Baere
Bert Callewaert
Björn Menten
C3
Conference
2023
Structural variants disrupt a critical regulatory region downstream of FOXG1
Eva D'haene
Lies Vantomme
Björn Menten
Bert Callewaert
Elfride De Baere
Sarah Vergult
C3
Conference
2023
Structural variants disrupt a critical regulatory region downstream of FOXG1
Lisa Hamerlinck
Eva D'haene
Maria del Rocio Pérez Baca
Lies Vantomme
Nore Van Loon
Björn Menten
Bert Callewaert
Elfride De Baere
Sarah Vergult
C3
Conference
2023
2022
A novel neurodevelopmental syndrome caused by loss-of-function of the Zinc Finger Homeobox 3 (ZFHX3) gene
Maria del Rocio Pérez Baca
Eva Jacobs
Lies Vantomme
Pontus LeBlanc
Elke Bogaert
Annelies Dheedene
Laurenz De Cock
Bart Dermaut
Aidin Foroutan
Jennifer Kerkhof
et al.
C3
Conference
2022
An optimized workflow for CRISPR/Cas9-mediated generation of indels and large deletions in induced pluripotent stem cells and neural stem cells
Lisa Hamerlinck
Maria del Rocio Pérez Baca
Lies Vantomme
Eva D'haene
Sarah Vergult
C3
Conference
2022
Benchmarking of long read structural variant callers using Oxford Nanopore data
Griet De Clercq
Bram Van Gaever
Lies Vantomme
Annelies Dheedene
Björn Menten
C3
Conference
2022
Benchmarking of long-read structural variant callers using Oxford Nanopore data
Griet De Clercq
Bram Van Gaever
Lies Vantomme
Annelies Dheedene
Björn Menten
C3
Conference
2022
Benchmarking of long-read structural variant callers using Oxford Nanopore data
Griet De Clercq
Bram Van Gaever
Lies Vantomme
Annelies Dheedene
Björn Menten
C3
Conference
2022
Benchmarking of long-read structural variant callers using in-house generated Oxford Nanopore data
Griet De Clercq
Bram Van Gaever
Lies Vantomme
Annelies Dheedene
Björn Menten
C3
Conference
2022
Long-read sequencing resolves cryptic structural variation in patients with syndromic intellectual disability
Griet De Clercq
Lies Vantomme
Bert Callewaert
Sarah Vergult
Annelies Dheedene
Björn Menten
C3
Conference
2022
Mapping the 3D genome of the human retina and its role in retinal disease
Eva D'haene
Victor Lopez Soriano
Lies Vantomme
Bernd Wissinger
Susanne Kohl
Sarah Vergult
Elfride De Baere
C3
Conference
2022
Regulatory landscaping : towards improved genetic diagnosis and therapy for SATB2-associated syndrome
Lisa Hamerlinck
Lies Vantomme
Eva D'haene
Sarah Vergult
Bert Callewaert
C3
Conference
2022
2021
A novel neurodevelopmental syndrome caused by loss-of-function of the Zinc Finger Homeobox 3 gene (ZFHX3)
Maria del Rocio Pérez Baca
Eva Jacobs
Lies Vantomme
Mareike Bauer
Melissa Bellini
Claire Beneteau
Natasha Brown
David Coman
Laurenz De Cock
Annelies Dheedene
et al.
C3
Conference
2021
Benchmarking of long-read structural variant callers on a recently released truth set using Oxford Nanopore data
Griet De Clercq
Bram Van Gaever
Lies Vantomme
Annelies Dheedene
Björn Menten
C3
Conference
2021
Benchmarking of long-read structural variant callers on a recently released truth set using Oxford Nanopore data
Griet De Clercq
Bram Van Gaever
Lies Vantomme
Annelies Dheedene
Björn Menten
C3
Conference
2021
Structural variants disrupt a critical regulatory region downstream of FOXG1
Eva D'haene
Lies Vantomme
Björn Menten
Bert Callewaert
Elfride De Baere
Sarah Vergult
C3
Conference
2021
2019
A neuronal enhancer network upstream of MEF2C is compromised in patients with Rett-like characteristics
Eva D'haene
Reut Bar-Yaacov
Inbar Bariah
Lies Vantomme
Sien Van Loo
Francisco Avila Cobos
Karen Verboom
Reut Eshel
Rawan Alatawna
Björn Menten
et al.
A1
Journal Article
in
HUMAN MOLECULAR GENETICS
2019
Noncoding structural variants disrupt the regulatory architecture of Rett genes
Eva D'haene
Reut Bar-Yaacov
Inbar Bariah
Lies Vantomme
Sien Van Loo
Francisco Avila Cobos
Karen Verboom
Reut Eshel
Rawan Alatawna
Björn Menten
et al.
C3
Conference
2019
Noncoding structural variants disrupt the regulatory architecture of Rett genes
Eva D'haene
Reut Bar-Yaacov
Inbar Bariah
Lies Vantomme
Sien Van Loo
Francisco Avila Cobos
Karen Verboom
Reut Eshel
Rawan Alatawna
Björn Menten
et al.
C3
Conference
2019
2018
A neuronal enhancer network upstream of MEF2C is compromised in patients with Rett-like characteristics
Eva D'haene
Reut Bar-Yaacov
Inbar Bariah
Lies Vantomme
Sien Van Loo
Francisco Avila Cobos
Karen Verboom
Reut Eshel
Rawan Alatawna
Björn Menten
et al.
C3
Conference
2018
CRISPR/Cas9-mediated genome editing in naïve human embryonic stem cells
Eva Jacobs
Sharat Warrier
Pieter-Jan Volders
Eva D'haene
Eva Vanlombergen
Lies Vantomme
Margot Van der Jeught
Björn Heindryckx
Björn Menten
Sarah Vergult
C3
Conference
2018
CRISPR/Cas9-mediated genome editing in naïve human embryonic stem cells
Eva Jacobs
Sharat Warrier
Pieter-Jan Volders
Eva D'haene
Eva Vanlombergen
Lies Vantomme
Margot Van der Jeught
Björn Heindryckx
Björn Menten
Sarah Vergult
C3
Conference
2018
The MEF2C regulatory network is disrupted in patients with Rett-like characteristics
Eva D'haene
Sarah Vergult
Reut Bar-Yaakov
Inbar Bariah
Lies Vantomme
Sien Van Loo
Francisco Avila Cobos
Reut Eshel
Rowan Alatawna
Ramon Birnbaum
et al.
C3
Conference
2018
The MEF2C regulatory network is disrupted in patients with Rett-like characteristics
Eva D'haene
Reut Bar-Yaakov
Inbar Bariah
Sien Van Loo
Lies Vantomme
Francisco Avila Cobos
Reut Eshel
Rowan Alatawna
Björn Menten
Ramon Birnbaum
et al.
C3
Conference
2018
2017
CRISPR/Cas9-mediated genome editing in naïve human embryonic stem cells
Eva Jacobs
Sharat Warrier
Pieter-Jan Volders
Eva D'haene
Eva Van Lombergen
Lies Vantomme
Margot Van der Jeught
Björn Heindryckx
Björn Menten
Sarah Vergult
A1
Journal Article
in
SCIENTIFIC REPORTS
2017
2015
Two siblings with homozygous pathogenic splice-site variant in mitochondrial asparaginyl-tRNA synthetase (NARS2)
Arnaud Vanlander
Björn Menten
Joél Smet
Linda De Meirleir
Tom Sante
Boel De Paepe
Sara Seneca
Sarah F Pearce
Christopher A Powell
Sarah Vergult
et al.
A1
Journal Article
in
HUMAN MUTATION
2015