Research Explorer

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Researcher

Leen Vanhoutte

Awards & Distinctions

27 Results

2021

Response to correspondence on 'Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles : a multi-center evaluation'

Channabasavaiah B. GurumurthyAidan R. O'BrienRolen M. QuadrosJr. Adams, JohnPilar AlcaideShinya AyabeJohnathan BallardSurinder K. BatraMarie-Claude BeauchampKathleen A. Becker et al.

A1 Journal Article in GENOME BIOLOGY

2019

A subset of type I conventional dendritic cells controls cutaneous bacterial infections through VEGFα-mediated recruitment of neutrophils

Baptiste JanelaAmit A PatelMai Chan LauChi Ching GohRasha MsallamWan Ting KongMichael FehlingsSandra HubertJosephine LumYannick Simoni et al.

A1 Journal Article in IMMUNITY

Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles : a multi-center evaluation

Channabasavaiah B. GurumurthyAidan R O'BrienRolen M QuadrosJohn AdamsPilar AlcaideShinya AyabeJohnathan BallardSurinder K BatraMarie-Claude BeauchampKathleen A Becker et al.

A1 Journal Article in GENOME BIOLOGY

2018

The generation and use of allergen-specific TCR transgenic animals

Manon VanheerswynghelsWendy ToussaintMartijn SchuijsLeen VanhoutteNigel KilleenHamida HammadBart Lambrecht

Bookchapter in Type 2 immunity : methods and protocols

Type III collagen affects dermal and vascular collagen fibrillogenesis and tissue integrity in a mutant Col3a1 transgenic mouse model

Sanne D'hondtBrecht GuillemynDelfien SyxSofie SymoensRiet De RyckeLeen VanhoutteWendy ToussaintBart LambrechtAnne De PaepeDouglas R Keene et al.

A1 Journal Article in MATRIX BIOLOGY

2017

TNFR1 inhibition with a nanobody protects against EAE development in mice

Sophie SteelandSara Van RyckeghemGriet Van ImschootRiet De RyckeWendy ToussaintLeen VanhoutteChristian VanhoveFilip De VosRoosmarijn VandenbrouckeClaude Libert

A1 Journal Article in SCIENTIFIC REPORTS

2016

IRF8 transcription factor controls survival and function of terminally differentiated conventional and plasmacytoid dendritic cells, respectively

Dorine SichienCharlotte ScottLiesbet MartensMatthias VanderkerkenSofie Van GassenMaud PlantingaThorsten JoerisSofie De PrijckLeen VanhoutteManon Vanheerswynghels et al.

A1 Journal Article in IMMUNITY

ORMDL3 expression levels have no influence on the activity of serine palmitoyltransferase

Assem ZhakupovaNincy DebeufMichiel KrolsWendy ToussaintLeen VanhoutteIrina AlecuZoltán KutalikPeter VollenweiderDaniela ErnstArnold von Eckardstein et al.

A1 Journal Article in FASEB JOURNAL

2015

Type III collagen is important for collagen fibrillogenesis and for dermal and cardiovascular development

Sanne D'hondtBrecht GuillemynSofie SymoensWendy ToussaintLeen VanhoutteRiet De RyckePaul CouckeBart LambrechtPatrick SegersAnne De Paepe et al.

Type III collagen is important for type I collagen fibrillogenesis and for dermal and cardiovascular development

Sanne D'hondtBrecht GuillemynSofie SymoensWendy ToussaintLeen VanhoutteRiet De RyckePaul CouckePatrick SegersBart LambrechtAnne De Paepe et al.

2013

Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF

Martin GuilliamsIsmé De KleerSandrine HenriSijranke PostLeen VanhoutteSofie De PrijckKim DeswarteBernard MalissenHamida HammadBart Lambrecht

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

Conventional and monocyte-derived CD11b⁺ dendritic cells initiate and maintain T helper 2 cell-mediated immunity to house dust mite allergen

Maud PlantingaMartin GuilliamsManon VanheerswynghelsKim DeswarteFilipe Branco MadeiraWendy ToussaintLeen VanhoutteKatrijn NeytNigel KilleenBernard Malissen et al.

A1 Journal Article in IMMUNITY

2012

Development of a novel COL3A1 transgenic mouse model for vascular Ehlers Danlos Syndrome

Yike KangSofie SymoensFransiska MalfaitPaul CouckeMarjolijn RenardBrecht GuillemynJulie De BackerFilipe Branco MadeiraWendy ToussaintLeen Vanhoutte et al.

2009

Assessment of a new in vitro maturation system for mouse and human cumulus-enclosed oocytes: three-dimensional prematuration culture in the presence of a phosphodiesterase 3-inhibitor

Leen VanhoutteDaniela NogueiraFrank DumortierPetra De Sutter

A1 Journal Article in HUMAN REPRODUCTION

Oocyte in vitro maturation

Daniela NogueiraSergio RomeroLeen VanhoutteDaniel Gustavo de MatosJohan Smitz

Bookchapter in Textbook of assisted reproductive technologies : laboratory an clinical perspectives

Prematuration of human denuded oocytes in a three-dimensional co-culture system: effects on meiosis progression and developmental competence

Leen VanhoutteDaniella NogueiraPetra De Sutter

A1 Journal Article in HUMAN REPRODUCTION

Strategies to improve in vitro maturation of human and mouse oocytes

Leen VanhouttePetra De Sutter

Use of phosphodiesterase type 3 inhibitor to improve IVM outcome: experimental set up matters

Daniela NogueiraLeen Vanhoutte

A1 Journal Article in FERTILITY AND STERILITY

2008

Effect of temporary nuclear arrest by phosphodiesterase 3-inhibitor on morphological and functional aspects of in vitro matured mouse Oocytes

Leen VanhoutteD NOGUEIRAJan GerrisMarc DhontPetra De Sutter

A1 Journal Article in MOLECULAR REPRODUCTION AND DEVELOPMENT

2007

Culture techniques to improve in vitro maturation of human oocytes

Leen VanhoutteJan GerrisMarc DhontPetra De Sutter

A2 Journal Article in Embryo Talk

High success rate of assisted oocyte activation after a diagnostic mouse oocyte activation test in couples with low or failed fertilization after ICSI

Björn HeindryckxStefanie De GheselleLeen VanhoutteJan GerrisMarc DhontPetra De Sutter

Ionophore treatment of mouse oocytes injected with human round-headed sperm does not lead to subsequent normal calcium oscillation pattern

Elke HeytensLeen VanhoutteSylvie LiermanClaude CuvelierJan GerrisMarc DhontPetra De SutterLuc Leybaert

Nuclear and cytoplasmic maturation of in vitro matured human oocytes after temporary nuclear arrest by phosphodiesterase 3-inhibitor

Leen VanhouttePetra De SutterD NOGUEIRAJan GerrisMarc DhontJosiane Van der Elst

A1 Journal Article in HUMAN REPRODUCTION

2006

Spindle morphology in human in vitro matured oocytes after temporary nuclear arrest by phosphodiesterase 3-inhibitor

Leen VanhouttePetra De SutterJan GerrisMarc DhontJosiane Van der Elst

2005

Clinical benefit of metaphase I oocytes

Leen VanhouttePetra De SutterJosiane Van der ElstMarc Dhont

A1 Journal Article in REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY

2004

Effects of chilling on structural aspects of early preantral mouse follicles

Leen VanhoutteRita CortvrindtDaniela NogueiraJohan Smitz

A1 Journal Article in BIOLOGY OF REPRODUCTION

2003

Effect of phosphodiesterase type 3 inhibitor on developmental competence of immature mouse oocytes in vitro

Daniela NogueiraRita CortvrindtDG De MatosLeen VanhoutteJohan Smitz

A1 Journal Article in BIOLOGY OF REPRODUCTION