Research Explorer

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Researcher

Jolien De Wyn

Awards & Distinctions

12 Results

2024

HTSplotter : an end-to-end data processing, analysis and visualisation tool for chemical and genetic in vitro perturbation screening

Carolina de Carvalho NunesJasper AnckaertFanny De VloedJolien De WynKaat DurinckJo VandesompeleFranki SpelemanVanessa Vermeirssen

A1 Journal Article in PLOS ONE

2022

HTSplotter : an end-to-end data processing, analysis and visualisation tool for chemical and genetic in vitro perturbation screening

Carolina de Carvalho NunesJasper AnckaertFanny De VloedJolien De WynKaat DurinckJo VandesompeleFranki SpelemanVanessa Vermeirssen

2021

MEIS2 is an adrenergic core regulatory transcription factor involved in early initiation of TH-MYCN-driven neuroblastoma formation

Jolien De WynMark W. ZimmermanNina Weichert-LeaheyCarolina de Carvalho NunesBelamy B. CheungBrian J. AbrahamAnneleen BeckersPieter-Jan VoldersBieke DecaestekerDaniel R. Carter et al.

A1 Journal Article in CANCERS

2018

SOX11 is a transcriptional circuit dosage sensitive transcription factor controlling SWI/SNF components

Bieke DecaestekerSara De BrouwerGeertrui DeneckerFanny De VloedWouter Van LoockeSuzanne VanhauwaertPauline DepuydtMoritz GartlgruberJolien De WynGenevieve Laureys et al.

TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets

Bieke DecaestekerGeertrui DeneckerChristophe Van NesteEmmy M DolmanWouter Van LoockeMoritz GartlgruberCarolina de Carvalho NunesFanny De VloedPauline DepuydtKaren Verboom et al.

A1 Journal Article in NATURE COMMUNICATIONS

The RRM2-PHF6 complex protects neuroblastoma cells from DNA damage accumulation to install a replication stress resistance phenotype

Carolina de Carvalho NunesKaat DurinckLisa DepestelSiebe LoontiensLouis DelhayeSofia ZanottiEmmy DolmanAline EggermontBieke DecaestekerPauline Depuydt et al.

2017

BRD3 as a specific vulnerable therapeutic target in neuroblastoma

Jolien De WynKaat DurinckAnneleen BeckersSiebe LoontiensSuzanne VanhauwaertDaniel CarterBelamy ChuengGlenn MarshallKatleen De PreterFrank Westermann et al.

SOX11 acts as part of the MYCN-WEE1 regulatory protein complex implicated in neuroblastoma

Bieke DecaestekerSara De BrouwerFanny De VloedGeertrui DeneckerSuzanne VanhauwaertJolien De WynGenevieve LaureysBjörn MentenPauline DepuydtPatrick Reynolds et al.

SOX11 acts as part of the MYCN-WEE1 regulatory protein complex implicated in neuroblastoma

Bieke DecaestekerSara De BrouwerFanny De VloedGeertrui DeneckerSuzanne VanhauwaertJolien De WynGenevieve LaureysBjörn MentenPauline DepuydtJo Vandorpe et al.

2016

An embryonic stem cell activated FOXM1 transcriptional program marks ultra-high-risk primary neuroblastoma patients for FDI-6 small molecule inhibition

Suzanne VanhauwaertCarina LeonelliSara De BrouwerJolien De WynAnneleen BeckersKaren SermonJo VandesompeleFranki SpelemanKatleen De Preter

The BRIP1/FANCJ DNA helicase is a druggable 17q driver oncogene involved in G-quadruplex induced replicative stress resistance in neuroblastoma

Suzanne VanhauwaertAnnelies FieuwCarina LeonelliBieke DecaestekerJolien De WynPauline DepuydtSara De BrouwerNadine Van RoyShuning HeThomas Look et al.

2015

An embryonic stem cell activated FOXM1 transcriptional program marks ultra-high-risk primary neuroblastoma patients for FDI-6 small molecule inhibition

Suzanne VanhauwaertCarina LeonelliSara De BrouwerJolien De WynAnneleen BeckersNeuroblastoma Research consortiumJo VandesompeleKaren SermonFranki SpelemanKatleen De Preter