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Researcher
Jolien De Wyn
Profile
Projects
Publications
Activities
Awards & Distinctions
11
Results
2022
HTSplotter : an end-to-end data processing, analysis and visualisation tool for chemical and genetic in vitro perturbation screening
Carolina de Carvalho Nunes
Jasper Anckaert
Fanny De Vloed
Jolien De Wyn
Kaat Durinck
Jo Vandesompele
Franki Speleman
Vanessa Vermeirssen
Preprint
2022
2021
MEIS2 is an adrenergic core regulatory transcription factor involved in early initiation of TH-MYCN-driven neuroblastoma formation
Jolien De Wyn
Mark W. Zimmerman
Nina Weichert-Leahey
Carolina de Carvalho Nunes
Belamy B. Cheung
Brian J. Abraham
Anneleen Beckers
Pieter-Jan Volders
Bieke Decaesteker
Daniel R. Carter
et al.
A1
Journal Article
in
CANCERS
2021
2018
SOX11 is a transcriptional circuit dosage sensitive transcription factor controlling SWI/SNF components
Bieke Decaesteker
Sara De Brouwer
Geertrui Denecker
Fanny De Vloed
Wouter Van Loocke
Suzanne Vanhauwaert
Pauline Depuydt
Moritz Gartlgruber
Jolien De Wyn
Genevieve Laureys
et al.
C3
Conference
2018
TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets
Bieke Decaesteker
Geertrui Denecker
Christophe Van Neste
Emmy M Dolman
Wouter Van Loocke
Moritz Gartlgruber
Carolina de Carvalho Nunes
Fanny De Vloed
Pauline Depuydt
Karen Verboom
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2018
The RRM2-PHF6 complex protects neuroblastoma cells from DNA damage accumulation to install a replication stress resistance phenotype
Carolina de Carvalho Nunes
Kaat Durinck
Lisa Depestel
Siebe Loontiens
Louis Delhaye
Sofia Zanotti
Emmy Dolman
Aline Eggermont
Bieke Decaesteker
Pauline Depuydt
et al.
C3
Conference
2018
2017
BRD3 as a specific vulnerable therapeutic target in neuroblastoma
Jolien De Wyn
Kaat Durinck
Anneleen Beckers
Siebe Loontiens
Suzanne Vanhauwaert
Daniel Carter
Belamy Chueng
Glenn Marshall
Katleen De Preter
Frank Westermann
et al.
C3
Conference
2017
SOX11 acts as part of the MYCN-WEE1 regulatory protein complex implicated in neuroblastoma
Bieke Decaesteker
Sara De Brouwer
Fanny De Vloed
Geertrui Denecker
Suzanne Vanhauwaert
Jolien De Wyn
Genevieve Laureys
Björn Menten
Pauline Depuydt
Jo Vandorpe
et al.
C3
Conference
2017
SOX11 acts as part of the MYCN-WEE1 regulatory protein complex implicated in neuroblastoma
Bieke Decaesteker
Sara De Brouwer
Fanny De Vloed
Geertrui Denecker
Suzanne Vanhauwaert
Jolien De Wyn
Genevieve Laureys
Björn Menten
Pauline Depuydt
Patrick Reynolds
et al.
C3
Conference
2017
2016
An embryonic stem cell activated FOXM1 transcriptional program marks ultra-high-risk primary neuroblastoma patients for FDI-6 small molecule inhibition
Suzanne Vanhauwaert
Carina Leonelli
Sara De Brouwer
Jolien De Wyn
Anneleen Beckers
Karen Sermon
Jo Vandesompele
Franki Speleman
Katleen De Preter
C3
Conference
2016
The BRIP1/FANCJ DNA helicase is a druggable 17q driver oncogene involved in G-quadruplex induced replicative stress resistance in neuroblastoma
Suzanne Vanhauwaert
Annelies Fieuw
Carina Leonelli
Bieke Decaesteker
Jolien De Wyn
Pauline Depuydt
Sara De Brouwer
Nadine Van Roy
Shuning He
Thomas Look
et al.
C3
Conference
2016
2015
An embryonic stem cell activated FOXM1 transcriptional program marks ultra-high-risk primary neuroblastoma patients for FDI-6 small molecule inhibition
Suzanne Vanhauwaert
Carina Leonelli
Sara De Brouwer
Jolien De Wyn
Anneleen Beckers
Neuroblastoma Research consortium
Jo Vandesompele
Karen Sermon
Franki Speleman
Katleen De Preter
C3
Conference
2015