Spatial mapping of mutant clones to understand the role of interclonal competition in human carcinogenesis.

A computational exploration of MHC-based immune selection signals in large cancer genome sequencing datasets

Computational approaches to facilitate the identification of novel therapeutic targets in neuroblastoma and other ALK- driven cancers

Determining the role of spatial clonal competition in the development of skin cancer

Spatial multi-omics exploration of neuroblastoma responses to novel treatments targetting the ALK-ATR-CHK1-RRM2 axis.

The identification of mutant clones and their spatial interactions in normal tissues derived from whole-body donors

A spatial multi-omics approach to determine the earliest clonal alterations underlying head and neck carcinogenesis.

Immunoediting and immune evasion mechanisms in the treated and untreated cancer genome

Spatial transcriptomics exploration of neuroblastoma responses to novel experimental drug treatments targeting the DNA damage response.

Studying human carcinogenesis using normal and tumoral postmortem tissues derived from whole body donors.

Understanding tumour-immune interactions and cancer immunotherapy responses from differential immune selection pressures in the cancer genome

Democratizing High-Throughput Next Generation Sequencing across different Life Science Fields: the AVITI Next Generation Sequencer.

Photolithographic DNA printer for massively parallel synthesis of DNA oligonucleotides for spatial - omics and hybrid capture target enrichment applications

Spatial-omics deciphering of cellular and molecular responses to enhanced MYCN/ATR-CHK1 synthetic lethality in high-risk neuroblastoma

Genetic predictors of joint shape and cartilage mechanics