Research Explorer

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Researcher

Jimmy Van den Eynden

35 Results

2022

A clinically annotated post-mortem approach to study multi-organ somatic mutational clonality in normal tissues

Tom LuijtsJoachim SiawJoris Van de VeldeElien BeylsArne ClaeysTim LammensWouter WillaertAnne VralJimmy Van den Eynden

A1 Journal Article in SCIENTIFIC REPORTS

Benchmark of tools for in silico prediction of MHC class I and class II genotypes from NGS data

Arne ClaeysJasper StautKathleen MarchalJimmy Van den Eynden

2021

ALK ligand ALKAL2 potentiates MYCN‐driven neuroblastoma in the absence of ALK mutation

Arne ClaeysJimmy Van den Eynden

A1 Journal Article in EMBO JOURNAL

ATR inhibition enables complete tumour regression in ALK-driven NB mouse models

Arne ClaeysJonatan Linus GabreJimmy Van den Eynden

A1 Journal Article in NATURE COMMUNICATIONS

Loss of RET promotes mesenchymal identity in neuroblastoma cells

Jonatan Linus GabreJimmy Van den Eynden

A1 Journal Article in CANCERS

Low immunogenicity of common cancer hot spot mutations resulting in false immunogenic selection signals

Arne ClaeysTom LuijtsKathleen MarchalJimmy Van den Eynden

A1 Journal Article in PLOS Genetics

Network-based analysis to identify drivers of metastatic prostate cancer using GoNetic

Louise de Schaetzen van BrienenGiles MiclotteMaarten LarmuseauJimmy Van den EyndenKathleen Marchal

A1 Journal Article in CANCERS

Pharmacologic RNA splicing modulation : a novel mechanism to enhance neoantigen-directed anti-tumor immunity and immunotherapy response

Jimmy Van den Eynden

Editorial material

2020

11q deletion or ALK activity curbs DLG2 expression to maintain an undifferentiated state in neuroblastoma

Jimmy Van den Eynden

A1 Journal Article in CELL REPORTS

Separating positional noise from neutral alignment in multicomponent statistical shape models

Emmanuel AudenaertJimmy Van den Eynden

A2 Journal Article in BONE REPORTS

2019

Lack of detectable neoantigen depletion signals in the untreated cancer genome

Jimmy Van den Eynden

A1 Journal Article in NATURE GENETICS

Targeting filamin A reduces macrophage activity and atherosclerosis

Jimmy Van den Eynden

A1 Journal Article in CIRCULATION

2018

An antisense RNA capable of modulating the expression of the tumor suppressor microRNA-34a

Jimmy Van den Eynden

A1 Journal Article in CELL DEATH & DISEASE

Clinical response of the novel activating ALK-I1171T mutation in neuroblastoma to the ALK inhibitor ceritinib

Jimmy Van den Eynden

A2 Journal Article in COLD SPRING HARBOR MOLECULAR CASE STUDIES

Elevated pyrimidine dimer formation at distinct genomic bases underlies promoter mutation hotspots in UV-exposed cancers

Jimmy Van den Eynden

A1 Journal Article in PLOS GENETICS

Phosphoproteome and gene expression profiling of ALK inhibition in neuroblastoma cell lines reveals conserved oncogenic pathways

Jimmy Van den Eynden

A1 Journal Article in SCIENCE SIGNALING

The genetic structure of the Belgian population

Jimmy Van den EyndenEls GoetghebeurHerman Van Oyen

A1 Journal Article in HUMAN GENOMICS

2017

Mutational signatures are critical for proper estimation of purifying selection pressures in cancer somatic mutation data when using the dN/dS metric

Jimmy Van den Eynden

A1 Journal Article in FRONTIERS IN GENETICS

Recurrent promoter mutations in melanoma are defined by an extended context-specific mutational signature

Jimmy Van den Eynden

A1 Journal Article in PLOS GENETICS

2016

Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events

Jimmy Van den Eynden

A1 Journal Article in NATURE COMMUNICATIONS

Simultaneous discovery of cancer subtypes and subtype features by molecular data integration

Ana Carolina Elisa Fierro GutierrezDries De MaeyerJimmy Van den EyndenLieven VerbekeKathleen Marchal

A1 Journal Article in BIOINFORMATICS

Somatic mutation patterns in hemizygous genomic regions unveil purifying selection during tumor evolution

Jimmy Van den Eynden

A1 Journal Article in PLOS GENETICS

2015

Pathway relevance ranking for tumor samples through network-based data integration

Lieven VerbekeJimmy Van den EyndenAna Carolina Elisa Fierro GutierrezPiet DemeesterJan FostierKathleen Marchal

A1 Journal Article in PLOS ONE

Pathway relevance ranking for tumor samples through network-based data integration (award for Outstanding Oral Poster Presentation )

Lieven VerbekeJimmy Van den EyndenPiet DemeesterKathleen MarchalJan Fostier

SomInaClust: detection of cancer genes based on somatic mutation patterns of inactivation and clustering

Jimmy Van den EyndenAna Carolina Elisa Fierro GutierrezLieven VerbekeKathleen Marchal

A1 Journal Article in BMC BIOINFORMATICS

2013

Identifying relevant pathways for different breast cancer subtypes using network based data integration

Lieven VerbekeJimmy Van den EyndenPiet DemeesterJan FostierKathleen Marchal

2011

Glycine enhances microglial intracellular calcium signaling : a role for sodium-coupled neutral amino acid transporters

Jimmy Van den Eynden

A1 Journal Article in PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

2010

The inhibitory neurotransmitter glycine modulates macrophage activity by activation of neutral amino acid transporters

Jimmy Van den Eynden

A1 Journal Article in JOURNAL OF NEUROSCIENCE RESEARCH

2009

Glycine and glycine receptor signalling in non-neuronal cells

Jimmy Van den Eynden

A1 Journal Article in FRONTIERS IN MOLECULAR NEUROSCIENCE

2007

A highly reliable and budget-friendly Peltier-cooled camera for biological fluorescence imaging microscopy

Jimmy Van den Eynden

A1 Journal Article in JOURNAL OF MICROSCOPY-OXFORD

Dorsal unpaired median neurons of Locusta migratoria express ivermectin- and fipronil-sensitive glutamate-gated chloride channels

Jimmy Van den Eynden

A1 Journal Article in JOURNAL OF NEUROPHYSIOLOGY

2004

Axillaire stagering met de schildwachtklier bij borstkanner : onze leercurve

Jimmy Van den Eynden

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Dopamine transporter SPECT using fast kinetic ligands : 123I-FP-β-CIT versus 99mTc-TRODAT-1

Jimmy Van den Eynden

A1 Journal Article in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Evaluation of anatomy based reconstruction for partial volume correction in brain FDG-PET

Jimmy Van den Eynden

A1 Journal Article in NEUROIMAGE

2003

De schildwachtklierprocedure bij de behandeling van het vulvacarcinoom : eerste resultaten bij een reeks van 32 patiënten

Jimmy Van den Eynden

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE