Research Explorer

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Researcher

Jelle Huysentruyt

Awards & Distinctions

12 Results

2025

RIPK1 ablation in T cells results in spontaneous enteropathy and TNF-driven villus atrophy

Jelle HuysentruytWolf SteelsMario Ruiz PérezBruno VerstraetenTatyana DivertKayleigh FliesKelly LemeireNozomi TakahashiElke De BruynMarie Joossens et al.

A1 Journal Article in EMBO REPORTS

Ripk1 is critical for preserving effector regulatory T cells and the suppressive transcriptional program in regulatory T cells

Carlos Plaza-SirventHannah SturmMaximilian K. NockeFatemeh GhorbaniClara BessenMarina C. Greweling-PilsStefan FloessJana NiemzJelle HuysentruytPeter Tougaard et al.

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

2024

RIPK1 protects naive and regulatory T cells from TNFR1-induced apoptosis

Jelle HuysentruytWolf SteelsMario Ruiz PérezBruno VerstraetenMike VadiTatyana DivertKayleigh FliesNozomi TakahashiBart LambrechtWim Declercq et al.

A1 Journal Article in CELL DEATH AND DIFFERENTIATION

TL1A and IL-18 synergy promotes GM-CSF-dependent thymic granulopoiesis in mice

Mario Ruiz PérezChristian MaueröderWolf SteelsBruno VerstraetenSahine LameireWei XieLaura WyckaertJelle HuysentruytTatyana DivertRia Roelandt et al.

A1 Journal Article in CELLULAR & MOLECULAR IMMUNOLOGY

Type 1 immunity enables neonatal thymic ILC1 production

Peter TougaardMario Ruiz PérezWolf SteelsJelle HuysentruytBruno VerstraetenJessica VettersTatyana DivertAmanda GonçalvesRia RoelandtNozomi Takahashi et al.

A1 Journal Article in SCIENCE ADVANCES

2023

Exploring the role of RIPK1 in T cell homeostasis

Jelle HuysentruytPeter VandenabeelePeter Tougaard

2022

Executioner caspases 3 and 7 are dispensable for intestinal epithelium turnover and homeostasis at steady state

Farzaneh GhazaviJelle HuysentruytJordy De ConinckStephanie KourulaSofie MartensBehrouz HassanniaTim WartewigTatyana DivertRia RoelandtBastian Popper et al.

A1 Journal Article in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting ferroptosis protects against experimental (multi)organ dysfunction and death

Samya Van CoillieEmily Van SanInes GoetschalckxBartosz WiernickiBanibrata MukhopadhyayWulf TonnusSze Men ChoiRia RoelandtCatalina DumitrascuLudwig Lamberts et al.

A1 Journal Article in NATURE COMMUNICATIONS

2021

Targeting ferroptosis protects against multiorgan dysfunction and death

Tom Vanden BergheSamya Van CoillieInes GoetschalckxBartosz WiernickiBanibrata MukhopadhyayWulf TonnusEmily Van SanSze Men ChoiRia RoelandtCatalina Dumitrascu et al.

2019

Heterodimerization of mu opioid receptor protomer with dopamine D2 receptor modulates agonist-induced internalization of mu opioid receptor

Lakshmi VasudevanDasiel O Borroto-EscuelaJelle HuysentruytKjell FuxeDeepak K SainiChristophe Stove

A1 Journal Article in BIOMOLECULES

Survival of single positive thymocytes depends upon developmental control of RIPK1 kinase signaling by the IKK complex independent of NF-κB

Louise V WebbAlessandro BarbaruloJelle HuysentruytTom Vanden BergheNozomi TakahashiSteven LeyPeter VandenabeeleBenedict Seddon

A1 Journal Article in IMMUNITY

2018

Design, synthesis, and biological evaluation of bivalent ligands targeting dopamine D2-like receptors and the μ-opioid receptor

Mingcheng QianLakshmi VasudevanJelle HuysentruytMartijn RisseeuwChristophe StovePatrick ML VanderheydenKathleen Van CraenenbroeckSerge Van Calenbergh

A1 Journal Article in CHEMMEDCHEM