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Onderzoeker
Hetty Helsmoortel
Profiel
Projecten
Publicaties
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Prijzen & Erkenningen
42
Resultaten
2024
Subpar reporting of pre-analytical variables in RNA-focused blood plasma studies
Céleste Van Der Schueren
Philippe Decruyenaere
Francisco Avila Cobos
Johanna Bult
Jill Deleu
Lydia Dipalo
Hetty Helsmoortel
Eva Hulstaert
Annelien Morlion
Elena Ramos Varas
et al.
U
Conferentie
2024
Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies
Céleste Van Der Schueren
Philippe Decruyenaere
Francisco Avila Cobos
Johanna Bult
Jill Deleu
Lydia Dipalo
Hetty Helsmoortel
Eva Hulstaert
Annelien Morlion
Elena Ramos Varas
et al.
A1
Artikel in een tijdschrift
in
MOLECULAR ONCOLOGY
2024
2023
Dramatic impact of blood collection tube and RNA purification method on extracellular RNA transcriptomes
Jasper Anckaert
Francisco Avila Cobos
Anneleen Decock
Philippe Decruyenaere
Jill Deleu
Katleen De Preter
Olivier De Wever
Jilke De Wilde
Bert Dhondt
Thibaut D'huyvetter
et al.
C3
Conferentie
2023
Performance evaluation of RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study
Anneleen Decock
Olivier De Wever
Celine Everaert
Hetty Helsmoortel
An Hendrix
Pieter Mestdagh
Annelien Morlion
Jo Vandesompele
Ruben Van Paemel
Francisco Avila Cobos
et al.
C3
Conferentie
2023
Performance evaluation of RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study
Anneleen Decock
Olivier De Wever
Celine Everaert
Hetty Helsmoortel
An Hendrix
Pieter Mestdagh
Annelien Morlion
Jo Vandesompele
Ruben Van Paemel
Francisco Avila Cobos
et al.
C3
Conferentie
2023
Reporting of pre-analytical variables in RNA-focused blood plasma studies : a prerequisite for quality assessment and replication
Céleste Van Der Schueren
Philippe Decruyenaere
Francisco Avila Cobos
Jill Deleu
Hetty Helsmoortel
Eva Hulstaert
Annelien Morlion
Kathleen Schoofs
Eveline Vanden Eynde
Kimberly Verniers
et al.
C3
Conferentie
2023
2022
Performance evaluation of RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study
Jasper Anckaert
Francisco Avila Cobos
Anneleen Decock
Philippe Decruyenaere
Jill Deleu
Katleen De Preter
Olivier De Wever
Jilke De Wilde
Bert Dhondt
Thibaut D'huyvetter
et al.
Preprint
2022
2021
Substantial performance differences among RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study
Anneleen Decock
Olivier De Wever
Celine Everaert
Hetty Helsmoortel
An Hendrix
Pieter Mestdagh
Annelien Morlion
Jo Vandesompele
Ruben Van Paemel
Francisco Avila Cobos
et al.
C3
Conferentie
2021
Substantial performance differences among RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study
Anneleen Decock
Olivier De Wever
Celine Everaert
Hetty Helsmoortel
An Hendrix
Pieter Mestdagh
Annelien Morlion
Jo Vandesompele
Ruben Van Paemel
Francisco Avila Cobos
et al.
C3
Conferentie
2021
2020
Performance assessment of total RNA sequencing of human biofluids and extracellular vesicles
Celine Everaert
Hetty Helsmoortel
Anneleen Decock
Eva Hulstaert
Ruben Van Paemel
Kimberly Verniers
Justine Nuytens
Jasper Anckaert
Nele Nijs
Joeri Tulkens
et al.
C3
Conferentie
2020
Substantial performance differences among RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control study-important considerations for liquid biopsies
Anneleen Decock
Jasper Anckaert
Celine Everaert
Justine Nuytens
Scott Kuersten
An Hendrix
Jo Vandesompele
Pieter Mestdagh
Bert Dhondt
Ruben Van Paemel
et al.
C3
Conferentie
2020
2019
Dramatic differences in RNA purification kit performance in the extracellular RNA quality control study : important considerations for liquid biopsies
Annelien Morlion
Jasper Anckaert
Francisco Avila Cobos
Anneleen Decock
Olivier De Wever
Bert Dhondt
Celine Everaert
Carolina Fierro
Hetty Helsmoortel
An Hendrix
et al.
C3
Conferentie
2019
Dramatic differences in RNA purification kit performance in the extracellular RNA quality control study : important considerations for liquid biopsies
Annelien Morlion
Jasper Anckaert
Francisco Avila Cobos
Anneleen Decock
Olivier De Wever
Bert Dhondt
Celine Everaert
Carolina Fierro
Hetty Helsmoortel
An Hendrix
et al.
C3
Conferentie
2019
Evaluating the impact of RNA purification kit and blood collection tube in the extracellular RNA quality control study : important considerations for liquid biopsies
Annelien Morlion
Jasper Anckaert
Francisco Avila Cobos
Anneleen Decock
Jill Deleu
Olivier De Wever
Bert Dhondt
Celine Everaert
Carolina Fierro
Hetty Helsmoortel
et al.
C3
Conferentie
2019
Lack of adequate reporting of pre-analytical variables in RNA based liquid biopsies studies hampers quality assessment and replication
Pieter Mestdagh
Jo Vandesompele
Céleste Van Der Schueren
Anneleen Decock
Hetty Helsmoortel
Eva Hulstaert
C3
Conferentie
2019
Long noncoding RNA expression profiling in cancer : challenges and opportunities
Lucia Lorenzi
Francisco Avila Cobos
Anneleen Decock
Celine Everaert
Hetty Helsmoortel
Steve Lefever
Karen Verboom
Pieter-Jan Volders
Franki Speleman
Jo Vandesompele
et al.
A1
Artikel in een tijdschrift
in
GENES CHROMOSOMES & CANCER
2019
Performance assessment of total RNA sequencing of human biofluids and extracellular vesicles
Celine Everaert
Hetty Helsmoortel
Anneleen Decock
Eva Hulstaert
Ruben Van Paemel
Kimberly Verniers
Justine Nuytens
Jasper Anckaert
Nele Nijs
Joeri Tulkens
et al.
A1
Artikel in een tijdschrift
in
SCIENTIFIC REPORTS
2019
2018
Circulating microRNA biomarkers for metastatic disease in neuroblastoma patients
Fjoralba Zeka
Anneleen Decock
Alan Van Goethem
Katrien Vanderheyden
Fleur Demuynck
Tim Lammens
Hetty Helsmoortel
Joëlle Vermeulen
Rosa Noguera
Ana P. Berbegall
et al.
A1
Artikel in een tijdschrift
in
JCI INSIGHT
2018
Circulating microRNA biomarkers for metastatic neuroblastoma
Fjoralba Zeka
Alan Van Goethem
Tim Lammens
Anneleen Decock
Hetty Helsmoortel
Genevieve Laureys
Michael Hogarty
Eveline Barbieri
Jason Shohet
Frank Berthold
et al.
C3
Conferentie
2018
Detecting long non-coding RNA biomarkers in prostate cancer liquid biopsies : hype or hope?
Hetty Helsmoortel
Celine Everaert
Nicolaas Lumen
Piet Ost
Jo Vandesompele
A2
Artikel in een tijdschrift
in
NON-CODING RNA RESEARCH
2018
Exploring the long non-coding RNA landscape in juvenile myelomonocytic leukemia
Mattias Hofmans
Tim Lammens
S Bresolin
H Cavé
C Flotho
H Hasle
Hetty Helsmoortel
M Van den Heuvel-Eibrink
C Niemeyer
J Stary
et al.
C3
Conferentie
2018
The extracellular RNA quality control (exRNAQC) study : controlling pre-analytical variables of RNA sequencing in blood-based precision medicine
Francisco Avila Cobos
Anneleen Decock
Katleen De Preter
Bert Dhondt
Olivier De Wever
Bram De Wilde
Celine Everaert
Carolina Fierro
Hetty Helsmoortel
An Hendrix
et al.
C3
Conferentie
2018
The extracellular RNA quality control (exRNAQC) study : controlling pre-analytical variables of RNA sequencing in blood-based precision medicine
Francisco Avila Cobos
Anneleen Decock
Katleen De Preter
Olivier De Wever
Bram De Wilde
Bert Dhondt
Celine Everaert
Carolina Fierro
Hetty Helsmoortel
An Hendrix
et al.
C3
Conferentie
2018
The long non-coding RNA landscape in juvenile myelomonocytic leukemia
Mattias Hofmans
Tim Lammens
Hetty Helsmoortel
Silvia Bresolin
Hélène Cavé
Christian Flotho
Henrik Hasle
Marry M van den Heuvel-Eibrink
Charlotte Niemeyer
Jan Stary
et al.
A1
Artikel in een tijdschrift
in
HAEMATOLOGICA
2018
2017
EV-TRACK : transparent reporting and centralizing knowledge in extracellular vesicle research
Jan Van Deun
Pieter Mestdagh
Patrizia Agostinis
Özden Akay
Sushma Anand
Jasper Anckaert
Zoraida Andreu Martinez
Tine Baetens
Els Beghein
Laurence Bertier
et al.
A1
Artikel in een tijdschrift
in
NATURE METHODS
2017
The extracellular RNA quality control (exRNAQC) study : testing and controlling pre-analytical variables of RNA sequencing on liquid biopsies
Anneleen Decock
Olivier De Wever
Bert Dhondt
Thibaut D'huyvetter
Hetty Helsmoortel
An Hendrix
Annouck Philippron
Kimberly Verniers
Pieter Mestdagh
Jo Vandesompele
C3
Conferentie
2017
Unravelling the biology of juvenile myelomonocytic leukaemia using transcriptomics
Hetty Helsmoortel
Tim Lammens
Pieter Van Vlierberghe
Barbara De Moerloose
A2
Artikel in een tijdschrift
in
BELGIAN JOURNAL OF HEMATOLOGY
2017
mRNA capture sequencing enabled liquid biopsy screening
Anneleen Decock
Olivier De Wever
Bert Dhondt
Carolina Fierro
An Hendrix
Hetty Helsmoortel
Scott Kuersten
Pieter Mestdagh
Nele Nijs
Piet Ost
et al.
C3
Conferentie
2017
2016
LIN28B is over-expressed in specific subtypes of pediatric leukemia and regulates lncRNA H19
Hetty Helsmoortel
Barbara De Moerloose
Tim Pieters
Farzaneh Ghazavi
Silvia Bresolin
Helene Cave
Andrica de Vries
Valerie de Haas
Christian Flotho
Veerle Labarque
et al.
A1
Artikel in een tijdschrift
in
HAEMATOLOGICA
2016
LIN28B is overexpressed in pediatric leukemia and regulates LNCRNA H19
Hetty Helsmoortel
Barbara De Moerloose
Silvia Bresolin
Hélèe Cavé
Christian Flotho
Charlotte Niemeyer
Jan Stary
Marry van den Heuvel-Eibrink
Pieter Van Vlierberghe
Tim Lammens
C3
Conferentie
2016
LIN28B overexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia
Hetty Helsmoortel
Silvia Bresolin
Tim Lammens
Hélène Cavé
Peter Noellke
Aurélie Caye
Farzaneh Ghazavi
Andrica de Vries
Henrik Hasle
Veerle Labarque
et al.
A1
Artikel in een tijdschrift
in
BLOOD
2016
Unique long non-coding RNA expression signature in ETV6/RUNX1-driven B-cell precursor acute lymphoblastic leukemia
Farzaneh Ghazavi
Barbara De Moerloose
Wouter Van Loocke
Annelynn Wallaert
Hetty Helsmoortel
Alina Ferster
Marleen Bakkus
Geneviève Plat
Eric Delabesse
Anne Uyttebroeck
et al.
A1
Artikel in een tijdschrift
in
ONCOTARGET
2016
Unraveling the biology of juvenile myelomonocytic leukemia using transcriptomics
Hetty Helsmoortel
Barbara De Moerloose
Tim Lammens
Pieter Van Vlierberghe
Proefschrift
2016
2015
CD200/BTLA deletions in pediatric precursor B-cell acute lymphoblastic leukemia treated according to the EORTC-CLG 58951 protocol
Farzaneh Ghazavi
Emmanuelle Clappier
Tim Lammens
Stefan Suciu
Aurélie Caye
Samira Zegrari
Marleen Bakkus
Nathalie Grardel
Yves Benoit
Odile Minckes
et al.
A1
Artikel in een tijdschrift
in
HAEMATOLOGICA
2015
MYCN-driven regulatory mechanisms controlling LIN28B in neuroblastoma
Anneleen Beckers
Gert Van Peer
Daniel R Carter
Moritz Gartlgruber
Carl Herrmann
Saurabh Agarwal
Hetty Helsmoortel
Kristina Althoff
Jan J Molenaar
Belamy B Cheung
et al.
A1
Artikel in een tijdschrift
in
CANCER LETTERS
2015
The long non-coding RNA H19 is regulated by LIN28B
Hetty Helsmoortel
Barbara De Moerloose
Tim Pieters
Farzaneh Ghazavi
S Bresolin
H Cavé
A Caye
ACH de Vries
C Flotho
V Labarque
et al.
C3
Conferentie
2015
2014
Juvenile myelomonocytic leukaemia: the quest for more specific therapies
Hetty Helsmoortel
Tim Lammens
Nadine Van Roy
Jan Philippé
Pascale De Paepe
Yves Benoit
Franki Speleman
Pieter Van Vlierberghe
Barbara De Moerloose
A2
Artikel in een tijdschrift
in
BELGIAN JOURNAL OF HEMATOLOGY
2014
LIN28B defines an aggressive subtype of juvenile myelomonocytic leukemia
Hetty Helsmoortel
Tim Lammens
Farzaneh Ghazavi
Aurelie Caye
Hélène Cavé
Christian Flotho
Charlotte Niemeyer
Jan Stary
Silvia Bresolin
Riccardo Masetti
et al.
C3
Conferentie
2014
Prognostic relevance of CD200/BTLA deletions in pediatric precursor-B cell acute lymphoblastic leukemia treated according to the EORTD-CLG 58951 protocol
Farzaneh Ghazavi
Tim Lammens
Emmanuelle Clappier
Stefan Suciu
Aurélie Caye
Samira Zegrari
Marleen Bakkus
Nathalie Grardel
Yves Benoit
Yves Bertrand
et al.
C3
Conferentie
2014
2013
miRNAs distinguish children with myelodysplastic syndrome from healthy donors
Hetty Helsmoortel
Tim Lammens
Pieter Mestdagh
Nadine Van Roy
Anne Uyttebroeck
Alina Ferster
Yves Benoit
Jo Vandesompele
Franki Speleman
Pieter Van Vlierberghe
et al.
C3
Conferentie
2013
miRNAs distinguish children with myelodysplastic syndrome from healthy donors
Hetty Helsmoortel
Tim Lammens
Pieter Mestdagh
Nadine Van Roy
Anne Uyttebroeck
Alina Ferster
Yves Benoit
Jo Vandesompele
Franki Speleman
Pieter Van Vlierberghe
et al.
C3
Conferentie
2013
2012
Study of the miRNome of childhood myelodysplastic syndrome
Hetty Helsmoortel
Tim Lammens
Nadine Van Roy
Anne Uyttebroeck
Alina Ferster
Yves Benoit
Franki Speleman
Barbara De Moerloose
C3
Conferentie
2012