Research Explorer

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Researcher

Els Goetghebeur

Awards & Distinctions

163 Results

2025

Factors associated with statural growth in pediatric kidney transplant recipients with focus on metabolic acidosis

Agnieszka Prytula-EbelsDries ReyndersEls GoetghebeurKai KrupkaJustine BacchettaNele KanzelmeyerIsabella GuzzoRaffaella LabbadiaElisa BenettiMohan Shenoy et al.

A1 Journal Article in PEDIATRIC NEPHROLOGY

2024

Budget impact projections for pharmaceuticals

Irina OdnoletkovaDries ReyndersFrederik De KeersmaekerStephan DevrieseEls GoetghebeurIrina Cleemput

Inverse probability of treatment weighting with generalized linear outcome models for doubly robust estimation

Erin E. GabrielMichael C. SachsTorben MartinussenIngeborg WaernbaumEls GoetghebeurStijn VansteelandtArvid Sjölander

A1 Journal Article in STATISTICS IN MEDICINE

PEACE V—Salvage Treatment of OligoRecurrent nodal prostate cancer Metastases (STORM) : acute toxicity of a randomized phase 2 trial

Piet OstShankar SivaSigmund BrabrandPiet DirixNick LiefhoogheFrançois-Xavier OtteAlfonso Gomez-IturriagaWouter EveraertsMohamed ShelanAntonio Conde-Moreno et al.

A1 Journal Article in EUROPEAN UROLOGY ONCOLOGY

Propensity weighting plus adjustment in proportional hazards model is not doubly robust

Erin E. GabrielMichael C. SachsIngeborg WaernbaumEls GoetghebeurPaul F. BlancheStijn VansteelandtArvid SjölanderThomas Scheike

A1 Journal Article in BIOMETRICS

The role of the estimand framework in the analysis of patient-reported outcomes in single-arm trials: a case study in oncology

Doranne ThomassenSatrajit RoychoudhuryCecilie Delphin AmdalDries ReyndersJammbe Z. MusoroWilli SauerbreiEls GoetghebeurSaskia le Cessie[ missing ] on behalf of the SISAQOL-IMI Work Package 3

A1 Journal Article in BMC MEDICAL RESEARCH METHODOLOGY

2023

Checkpoint Inhibitors in Combination With Stereotactic Body Radiotherapy in Patients With Advanced Solid Tumors The CHEERS Phase 2 Randomized Clinical Trial

Mathieu SpaasNora SundahlVibeke KruseSylvie RotteyDaan De MaeseneerFréderic DuprezYolande LievensVeerle SurmontLieve BrochezDries Reynders et al.

U Journal Article in JAMA ONCOLOGY

Checkpoint inhibitors in combination with stereotactic body radiotherapy in patients with advanced solid tumors : the CHEERS phase 2 randomized clinical trial

Mathieu SpaasNora SundahlVibeke KruseSylvie RotteyDaan De MaeseneerFréderic DuprezYolande LievensVeerle SurmontLieve BrochezDries Reynders et al.

A1 Journal Article in JAMA ONCOLOGY

Evaluation of tuberculosis diagnostic test accuracy using Bayesian latent class analysis in the presence of conditional dependence between the diagnostic tests used in a community-based tuberculosis screening study

Alfred KeterLutgarde LynenAlastair Van HeerdenEmily WongKlaus ReitherEls GoetghebeurBart K. M. Jacobs

A1 Journal Article in PLOS ONE

Single-arm studies involving patient-reported outcome data in oncology : a literature review on current practice

Limin LiuJungyeon ChoiJammbe Z. MusoroWilli SauerbreiCecilie Delphin AmdalAhu AlanyaYolanda BarbachanoJoseph C. CappelleriRagnhild Sørum FalkMallorie H. Fiero et al.

A1 Journal Article in LANCET ONCOLOGY

Statistical methods to guide clinical decision-making in tuberculosis

Alfred KeterEls GoetghebeurLutgarde LynenBart K.M. JacobsAlastair Van Heerden

2022

Implications of covariate induced test dependence on the diagnostic accuracy of latent class analysis in pulmonary tuberculosis

Alfred KeterLutgarde LynenAlastair Van HeerdenEls GoetghebeurBart K. M. Jacobs

A2 Journal Article in JOURNAL OF CLINICAL TUBERCULOSIS AND OTHER MYCOBACTERIAL DISEASES

PEACE V - STORM randomized phase II trial for oligorecurrent nodal prostate cancer : acute toxicity

T. ZilliS. SivaR. HeikkilaP. DirixN. LiefhoogheF. OtteA. Gomez-IturriagaW. EveraertsM. ShelanA. Conde-Moreno et al.

Trial emulation and survival analysis for disease incidence registers : a case study on the causal effect of pre-emptive kidney transplantation

Camila Olarte ParraIngeborg WaernbaumStaffan SchönEls Goetghebeur

A1 Journal Article in STATISTICS IN MEDICINE

2021

Checkpoint inhibition in combination with an immunoboost of external beam radiotherapy in solid tumors (CHEERS) : study protocol for a phase 2, open-label, randomized controlled trial

Mathieu SpaasNora SundahlEva HulstaertVibeke KruseSylvie RotteyDaan De MaeseneerVeerle SurmontAnnabel MeiresonLieve BrochezDries Reynders et al.

A1 Journal Article in BMC CANCER

Consistency of causal claims in observational studies : a review of papers published in a general medical journal

Camila Olarte ParraLorenzo BertizzoloSara SchroterAgnes DechartresEls Goetghebeur

A1 Journal Article in BMJ OPEN

Simon DayEls GoetghebeurJoel GreenhouseRobert Platt

Editorial material

Evaluating the prognostic performance of a polygenic risk score for breast cancer risk stratification

Maria OlsenKrista FischerPatrick M. BossuytEls Goetghebeur

A1 Journal Article in BMC CANCER

Framework for the treatment and reporting of missing data in observational studies : the Treatment And Reporting of Missing data in Observational Studies framework

Katherine J. LeeKate M. TillingRosie P. CornishRoderick J. A. LittleMelanie L. BellEls GoetghebeurJoseph W. HoganJames R. Carpenter[ missing ] on behalf of the STRATOS initiative

A1 Journal Article in JOURNAL OF CLINICAL EPIDEMIOLOGY

Immuno-radiotherapy in solid tumors : preliminary results of the randomized phase 2 CHEERS trial

Mathieu SpaasNora SundahlSylvie RotteyVIBEKE KRUSEDaan De MaeseneerFréderic DuprezPiet DirixVeerle SurmontYolande LievensRobin Van den Begin et al.

Motion-control shoes reduce the risk of pronation-related pathologies in recreational runners : a secondary analysis of a randomized controlled trial

Tine WillemsChristophe LeyEls GoetghebeurDaniel TheisenLaurent Malisoux

A1 Journal Article in JOURNAL OF ORTHOPAEDIC & SPORTS PHYSICAL THERAPY

Prognostic value of high-risk human papillomavirus DNA and p16(INK4)(a) immunohistochemistry in patients with anal cancer : an individual patient data meta-analysis

Theresa ObermuellerJoris HautekietMaria Paula BustoDries ReyndersLiliana BelgioiaAnnemieke CatsDuncan C. GilbertStefan A. KoerberSabine MaiDidier Meulendijks et al.

A1 Journal Article in EUROPEAN JOURNAL OF CANCER

Reply to 'The perceived efficacy of hydroxychloroquine in observational studies : the results of the confounding effects of goals of care'

Nicolas DaubyJoris HautekietLucy CatteauMarion MontourcyDominique Van BeckhovenEmmanuel BottieauEls Goetghebeur

A1 Journal Article in INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

The multicenter, randomized, phase 2 PEACE V-STORM trial : defining the best salvage treatment for oligorecurrent nodal prostate cancer metastases

Thomas ZilliPiet DirixReino HeikkilaNick LiefhoogheShankar SivaAlfonso Gomez-IturriagaWouter EveraertsFrancois OtteMohamed ShelanCarole Mercier et al.

Editorial material

2020

Causal inference from observational studies in clinical research : lessons learned from kidney transplantation and beyond

Camila Olarte ParraEls GoetghebeurAeilko Zwinderman

Simon DayEls GoetghebeurJoel Greenhouse

Editorial material

Formulating causal questions and principled statistical answers

Els GoetghebeurSaskia le CessieBianca De StavolaErica E. M. MoodieIngeborg Waernbaum

A1 Journal Article in STATISTICS IN MEDICINE

Low-dose hydroxychloroquine therapy and mortality in hospitalised patients with COVID-19 : a nationwide observational study of 8075 participants

Lucy CatteauNicolas DaubyMarion MontourcyEmmanuel BottieauJoris HautekietEls GoetghebeurSabrina van IersselEls DuysburghHerman Van OyenChloé Wyndham-Thomas et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

PEACE V - Salvage Treatment of OligoRecurrent nodal prostate cancer Metastases (STORM) : a study protocol for a randomized controlled phase II trial

Aurélie De BruyckerAn SpiessensP. DirixN. KoutsouvelisI. SemacN. LiefhoogheA. Gomez-IturriagaW. EveraertsF. OtteA. Papachristofilou et al.

A1 Journal Article in BMC CANCER

2019

Metastasis-directed therapy in treating nodal oligorecurrent prostate cancer : a multi-institutional analysis comparing the outcome and toxicity of stereotactic body radiotherapy and elective nodal radiotherapy

Elise De BleserBarbara Alicja Jereczek-FossaDavid PasquierThomas ZilliNicholas Van AsAndrei FodorPiet DirixAlfonso Gomez-IturriagaFabio TrippaShankar Siva et al.

A1 Journal Article in EUROPEAN UROLOGY

Prognostic significance of number versus location of positive mesenteric nodes in stage iii colon cancer

Kozo KataokaHannes YsebaertManabu ShiozawaDries ReyndersMasataka IkedaNaohiro TomitaEls GoetghebeurWim Ceelen

A1 Journal Article in EJSO

Randomized phase 1 trial of pembrolizumab with neo-adjuvant versus concomitant stereotactic body radiotherapy in metastatic urothelial carcinoma: Clinical and translational results

Piet OstNora SundahlG VandekerkhoveKarel DecaesteckerAnnabel MeiresonPieter De VisschereValerie FonteyneDaan De MaeseneerDries ReyndersEls Goetghebeur et al.

Randomized phase 1 trial of pembrolizumab with sequential versus concomitant stereotactic body radiotherapy in metastatic urothelial carcinoma

Nora SundahlGillian VandekerkhoveKarel DecaesteckerAnnabel MeiresonPieter De VisschereValerie FonteyneDaan De MaeseneerDries ReyndersEls GoetghebeurJo Van Dorpe et al.

A1 Journal Article in EUROPEAN UROLOGY

Randomized phase I trial of pembrolizumab with neo-adjuvant versus concomitant stereotactic body radiotherapy in metastatic urothelial carcinoma : clinical and translational results

Gillian VandekerkhoveNora SundahlKarel DecaesteckerAnnabel MeiresonPieter De VisschereValerie FonteyneDaan De MaeseneerDries ReyndersEls GoetghebeurJo Van Dorpe et al.

2018

Assessing factors associated with long-term work disability after cancer in Belgium : a population-based cohort study using competing risks analysis with a 7-year follow-up

Regine Levo Kiasuwa MbengiAlina Mioara NicolaieEls GoetghebeurRenee OtterKatrien MortelmansSarah MissinnneMarc ArbynCatherine BoulandChristophe de Brouwer

A1 Journal Article in BMJ OPEN

Flanders’ training network for methodology and statistics (FLAMES)

Emmanuel AbatihAn CarbonezKaren FrançoisEls GoetghebeurKoen Plevoets

Phase 1 dose escalation trial of ipilimumab and stereotactic body radiation therapy in metastatic melanoma

Nora SundahlKatrien De WolfVibeke KruseAnnabel MeiresonDries ReyndersEls GoetghebeurMireille Van GeleReinhart SpeeckaertBenjamin HennartLieve Brochez et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Pre-emptive versus non pre-emptive kidney transplantation for end-stage kidney disease

Camila Olarte ParraCedric Van de BruaeneLaurens WeynantsEvi NaglerAlexandra McAleenanRoy G ElbersJulian PT HigginsEls Goetghebeur

A2 Journal Article in COCHRANE DATABASE OF SYSTEMATIC REVIEWS

Prognostic significance of number versus location of positive mesenteric nodes in node positive colon cancer

Kozo KataokaElke DebrieManabu ShiozawaEls GoetghebeurWim Ceelen

Surveillance or metastasis-directed therapy for oligometastatic prostate cancer recurrence : a prospective, randomized, multicenter phase II trial

Piet OstDries ReyndersKarel DecaesteckerValerie FonteyneNicolaas LumenAurélie De BruyckerBieke LambertLouke DelrueRenée BultijnckTom Claeys et al.

A1 Journal Article in JOURNAL OF CLINICAL ONCOLOGY

The genetic structure of the Belgian population

Jimmy Van den EyndenTine DescampsEls DelporteNancy HC RoosensSigrid CJ De KeersmaeckerVanessa De WitJoris Robert VermeeschEls GoetghebeurJean TafforeauStefaan Demarest et al.

A1 Journal Article in HUMAN GENOMICS

2017

A phase I/II trial of fixed-dose stereotactic body radiotherapy with sequential or concurrent pembrolizumab in metastatic urothelial carcinoma : evaluation of safety and clinical and immunologic response

Nora SundahlKatrien De WolfSylvie RotteyKarel DecaesteckerDaan De MaeseneerAnnabel MeiresonEls GoetghebeurValerie FonteyneSofie VerbekePieter De Visschere et al.

A1 Journal Article in JOURNAL OF TRANSLATIONAL MEDICINE

BelPHG-21 : a pilot study on genetic variability in the Belgian population

Tine DescampsEls DelporteJoris Robert VermeerschEls GoetghebeurLieven ClementJean TafforeauStefaan DemarestHerman Van OyenMarc Van den BulckeJimmy Van den Eynden

Combined high dose radiation and pazopanib in metastatic renal cell carcinoma : a phase I dose escalation trial

Katrien De WolfSylvie RotteyKarim VermaelenKarel DecaesteckerNora SundahlLizzy De LobelEls GoetghebeurGert De MeerleerNicolaas LumenValerie Fonteyne et al.

A1 Journal Article in RADIATION ONCOLOGY

Confronting bias and precision in digital PCR quantification

Bart JacobsEls GoetghebeurLieven Clement

Cure of cancer for seven cancer sites in the Flemish Region

Geert SilversmitDavid JegouEvelien VaesEls GoetghebeurLiesbet Van Eycken

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

Different pediatric survival after cardiac arrest

Camila Olarte ParraLinda NyanchokaEls Goetghebeur

A1 Journal Article in JAMA PEDIATRICS

Model-based classification for digital PCR : your Umbrella for rain

Bart JacobsEls GoetghebeurJo VandesompeleAriane De GanckNele NijsAnneleen BeckersNina PapazovaNancy H RoosensLieven Clement

A1 Journal Article in ANALYTICAL CHEMISTRY

2016

Effect of neoadjuvant radiation dose and schedule on nodal count and its prognostic impact in stage II–III rectal cancer

Wim CeelenWouter WillaertMachteld VarewyckSasha LibbrechtEls GoetghebeurPiet Pattyn

A1 Journal Article in ANNALS OF SURGICAL ONCOLOGY

Marginal structural and structural nested models for causal inference in hospital epidemiology

Karl MertensStijn VansteelandtEls Goetghebeur

On the practice of ignoring center-patient interactions in evaluating hospital performance

Machteld VarewyckStijn VansteelandtMarie ErikssonEls Goetghebeur

A1 Journal Article in STATISTICS IN MEDICINE

Prognostic significance of nodal count and lymph node ratio in irradiated rectal cancer

Wim CeelenWouter WillaertMachteld VarewyckEls GoetghebeurPiet Pattyn

The importance of integrating clinical relevance and statistical significance in the assessment of quality of care : illustrated using the Swedish Stroke Register

Anita LindmarkBart Van RompayeEls GoetghebeurEva-Lotta GladerMarie Eriksson

A1 Journal Article in PLOS ONE

Validation of a sampling method to collect exposure data for central-line-associated bloodstream infections

Naïma HammamiKarl MertensRosanna OverholserEls GoetghebeurBoudewijn CatryMarie-Laurence Lambert

A1 Journal Article in INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

2015

Biological 18[F]-FDG-PET image-guided dose painting by numbers for painful uncomplicated bone metastases: a 3-arm randomized phase II trial

Dieter BerwoutsKatrien De WolfBieke LambertRenée BultijnckWilfried De NeveLizzy De LobelLennart JansEls GoetghebeurBruno SpeleersAna Maria Luiza Olteanu et al.

A1 Journal Article in RADIOTHERAPY AND ONCOLOGY

Evaluating hospital performance based on excess cause-specific incidence

Bart Van RompayeMarie ErikssonEls Goetghebeur

A1 Journal Article in STATISTICS IN MEDICINE

On quantifying quality of care

Machteld VarewyckEls GoetghebeurStijn Vansteelandt

2014

An alternative method for assessing quality of care : illustrated using data from Riks-Stroke, the Swedish stroke register

A. LindmarkBart Van RompayeEls GoetghebeurE-L GladerM Eriksson

Impact of variance components on reliability of absolute quantification using digital PCR

Bart JacobsEls GoetghebeurLieven Clement

A1 Journal Article in BMC BIOINFORMATICS

On shrinkage and model extrapolation in the evaluation of clinical center performance

Machteld VarewyckEls GoetghebeurMarie ErikssonStijn Vansteelandt

A1 Journal Article in BIOSTATISTICS

2013

Crossover studies with survival outcomes

Jozefien BuyzeEls Goetghebeur

A1 Journal Article in STATISTICAL METHODS IN MEDICAL RESEARCH

Evaluating dynamic treatment strategies: does it have to be more costly?

Jozefien BuyzeEls Goetghebeur

A1 Journal Article in PHARMACEUTICAL STATISTICS

2012

Enhanced analysis of real-time PCR data by using a variable efficiency model : FPK-PCR

Antoon LievensStefan Van AelstMarc Van den BulckeEls Goetghebeur

A1 Journal Article in NUCLEIC ACIDS RESEARCH

Estimation with Cox models: cause-specific survival analysis with misclassified cause of failure

Bart Van RompayeShabbar JaffarEls Goetghebeur

A1 Journal Article in EPIDEMIOLOGY

Explaining time to cause-specific events: uncovering information amidst noise and errors in an imperfect world

Bart Van RompayeEls Goetghebeur

Simulation of between repeat variability in real time PCR reactions

Antoon LievensStefan Van AelstMarc Van den BulckeEls Goetghebeur

A1 Journal Article in PLOS ONE

The Ghent Marfan trial: a randomized, double-blind placebo controlled trial with losartan in Marfan patients treated with β-blockers

Katarina MöbergSylvia De NobeleDaniel DevosEls GoetghebeurPatrick SegersBram TrachetChris VervaetMarjolijn RenardPaul CouckeBart Loeys et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF CARDIOLOGY

2011

A diagnostic modelling framework to construct indices of biotic integrity: a case study of fish in the Zeeschelde estuary (Belgium)

Paul QuataertPieter VerscheldenJan BreineGeert VerbekeEls GoetghebeurFrans Ollevier

A1 Journal Article in ESTUARINE COASTAL AND SHELF SCIENCE

A structural mean model to allow for noncompliance in a randomized trial comparing 2 active treatments

Krista FischerEls GoetghebeurBernard VrijensIan R White

A1 Journal Article in BIOSTATISTICS

Assurance de qualité pour le cancer rectal : phase 3 : méthodes statistique visant à comparer les centres sur base d'un ensemble d'indicateurs de qualité

Els GoetghebeurRonan Van RossemKatrien BaertKürt VanhoutteTom BoterbergPieter DemetterMark De RidderDavid HarringtonMarc PeetersGuy Storme et al.

Causal inference: sense and sensitivity versus prior and prejudice

Els Goetghebeur

Bookchapter in Computermodelle in der Wissenschaft : zwischen Analyse, Vorhersage and Suggestion

Kwaliteit van rectale kankerzorg : fase 3 : statistische methoden om centra te benchmarken met een set van kwaliteitsindicatoren

Els GoetghebeurRonan Van RossemKatrien BaertKürt VanhoutteTom BoterbergPieter DemetterMark HarringtonDavid PeetersGuy StormeJohanna Verhulst et al.

On instrumental variables estimation of causal odds ratios

Stijn VansteelandtJack BowdenManoochehr BabanezhadEls Goetghebeur

A1 Journal Article in STATISTICAL SCIENCE

Quality assurance of rectal cancer diagnosis and treatment - phase 3 : statistical methods to benchmark centres on a set of quality indicators

Els GoetghebeurRonan Van RossemKatrien BaertKürt VanhoutteTom BoterbergPieter DemetterMark De RidderDavid HarringtonMarc PeetersGuy Storme et al.

2010

Adherence and its measurement in phase 2/3 microbicide trials

Elizabeth E TolleyPolly F HarrisonEls GoetghebeurKathleen MorrowRobert PoolDoug TaylorStephanie N TillmanAriane van der Straten

A1 Journal Article in AIDS AND BEHAVIOR

Commentary: To cause or not to cause confusion vs transparency with Mendelian Randomization

Els Goetghebeur

Editorial material

Comparison of causal effect estimators under exposure misclassification

Manoochehr BabanezhadStijn VansteelandtEls Goetghebeur

A1 Journal Article in JOURNAL OF STATISTICAL PLANNING AND INFERENCE

Design and testing for clinical trials faced with misclassified causes of death

Bart Van RompayeEls GoetghebeurShabbar Jaffar

A1 Journal Article in BIOSTATISTICS

Designing a sequentially randomized study with adherence enhancing interventions for diabetes patients

Jozefien BuyzeBart Van RompayeEls Goetghebeur

A1 Journal Article in STATISTICS IN MEDICINE

2009

CORRECTING INSTRUMENTAL VARIABLES ESTIMATORS FOR SYSTEMATIC MEASUREMENT ERROR

Stijn VansteelandtManoochehr BabanezhadEls Goetghebeur

A1 Journal Article in STATISTICA SINICA

Impact of allelic dropout on evidential value of forensic DNA profiles

Filip Van NieuwerburghEls GoetghebeurMado VandewoestyneDieter Deforce

A1 Journal Article in BIOINFORMATICS

Marginal structural models for partial exposure regimes

Stijn VansteelandtKarl MertensCarl SuetensEls Goetghebeur

A1 Journal Article in BIOSTATISTICS

Measurement error and causal inference with instrumental variables

Manoochehr BabanezhadEls GoetghebeurStijn Vansteelandt

RMNE probability of Forensic DNA profiles with allelic drop-out

Filip Van NieuwerburghEls GoetghebeurMado VandewoestyneDieter Deforce

A2 Journal Article in Forensic science international. Genetics

2008

Estimation of controlled direct effects

Sylvie GoetgelukStijn VansteelandtEls Goetghebeur

A1 Journal Article in JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

From clustered data to causal inference : new methodology motivated by the analysis of subfertility treatments

Sylvie GoetgelukStijn VansteelandtEls Goetghebeur

Optimal screening for promising genes in 2-stage designs

Beatrijs MoerkerkeEls Goetghebeur

A1 Journal Article in BIOSTATISTICS

2007

Model evaluation based on the sampling distribution of estimated absolute prediction error

Lu TianTianxi CaiEls GoetghebeurL.J. Wei

A1 Journal Article in BIOMETRIKA

2006

Genome-wide screening for cis-regulatory variation using a classical diallel crossing scheme

Raphaël KiekensAnnelies VercauterenBeatrijs MoerkerkeEls GoetghebeurHilde Van Den DaeleRoel SterkenMartin KuiperFred van EeuwijkMarnik Vuylsteke

A1 Journal Article in NUCLEIC ACIDS RESEARCH

Ignorance and uncertainty regions as inferential tools in a sensitivity analysis

Stijn VansteelandtEls GoetghebeurMG KENWARDG MOLENBERGHS

A1 Journal Article in STATISTICA SINICA

Selecting "significant" differentially expressed genes from the combined perspective of the null and the alternative

Beatrijs MoerkerkeEls Goetghebeur

A1 Journal Article in JOURNAL OF COMPUTATIONAL BIOLOGY

Significance and impotence: towards a balanced view of the null and the alternative hypotheses in marker selection for plant breeding

Beatrijs MoerkerkeEls GoetghebeurJ DE RIEKIsabel Roldán-Ruiz

A1 Journal Article in JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES A-STATISTICS IN SOCIETY

2005

Analysing compliance in clinical trials

Graham DunnEls Goetghebeur

Editorial material

Causal proportional hazards models and time-constant exposure in randomized clinical trials

Tom LoeysEls GoetghebeurAn Vandebosch

A1 Journal Article in LIFETIME DATA ANALYSIS

Comparison of three assays for the quantification of Candida biomass in suspension and CDC reactor grown biofilms

Kris HonraetEls GoetghebeurHans Nelis

A1 Journal Article in JOURNAL OF MICROBIOLOGICAL METHODS

Compliance and survival analysis

Els Goetghebeur

Bookchapter in Encyclopedia of Biostatistics, Second Edition

Identification of molecular markers linked with crown rust (Puccinia coronata f. sp lolii) resistance in perennial ryegrass (Lolium perenne) using AFLP markers and a bulked segregant approach

H MuylleJ BaertErik Van BockstaeleBeatrijs MoerkerkeEls GoetghebeurIsabel Roldán-Ruiz

A1 Journal Article in EUPHYTICA

Kangaroo vs. porcine aortic valves : calcification potential after glutaraldehyde fixation

RAJKISHAN NARINECyrille C ChéryEls GoetghebeurRamses ForsythErik ClaeysMaria CornelissenLuc MoensGuido Van Nooten

A1 Journal Article in EUROPEAN SURGICAL RESEARCH

Least squares estimation

Stijn VansteelandtEls Goetghebeur

Bookchapter in Encyclopaedic Companion to Medical Statistics

Maximum likelihood estimation

Stijn VansteelandtEls Goetghebeur

Bookchapter in Encyclopaedic Companion to Medical Statistics

Els GoetghebeurStijn Vansteelandt

Bookchapter in Encyclopaedic Companion to Medical Statistics

Modelling the association between adherence and viral load in HIV-infected patients

B VRIJENSEls GoetghebeurE DE KLERKR RODES MAYERJ URQUHART

A1 Journal Article in STATISTICS IN MEDICINE

On the viral safety of plasma pools and plasma derivatives

Stijn VansteelandtEls GoetghebeurI THOMASE MATHYSF VAN LOOCK

A1 Journal Article in JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES A-STATISTICS IN SOCIETY

Permutation based methods for comparing quality of life between observed treatments

Beatrijs MoerkerkeEls GoetghebeurKristel Van SteenSimon Van BelleVeronique Cocquyt

A1 Journal Article in STATISTICS IN MEDICINE

Preterm birth in twins after subfertility treatment: population based cohort study

Hans VerstraelenSylvie GoetgelukC DEROMStijn VansteelandtRobert DeromEls GoetghebeurNA TEMMERMAN

A1 Journal Article in BRITISH MEDICAL JOURNAL

Sense and sensitivity when correcting for observed exposures in randomized clinical trials

Stijn VansteelandtEls Goetghebeur

A1 Journal Article in STATISTICS IN MEDICINE

Structural accelerated failure time models for the effects of observed exposures on repeated events in a clinical trial

An VandeboschEls GoetghebeurL VAN DAMME

A1 Journal Article in STATISTICS IN MEDICINE

Structural mean models for compliance analysis in randomized clinical trials and the impact of errors on measures of exposure

Els GoetghebeurStijn Vansteelandt

A1 Journal Article in STATISTICAL METHODS IN MEDICAL RESEARCH

2004

Acceptability of COL-1492, a vaginal gel, among sex workers in one Asian and three African cities

An VandeboschEls GoetghebeurG RAMJEEM ALARYV ETTIEGNE-TRAOREV CHANDEYINGL VAN DAMME

A1 Journal Article in SEXUALLY TRANSMITTED INFECTIONS

Discussion of nonparametric and semiparametric regression

JS MARRONHG MULLERJ RICEJL WANGNY WANGYD WANGM DAVIDIANP DIGGLED FOLLMANNTA LOUIS et al.

Editorial material

Electronic monitoring of variation in drug intakes can reduce bias and improve precision in pharmacokinetic/pharmacodynamic population studies

B VRIJENSEls Goetghebeur

A1 Journal Article in STATISTICS IN MEDICINE

Structural mean effects of noncompliance: Estimating interaction with baseline prognosis and selection effects

Krista FischerEls Goetghebeur

A1 Journal Article in JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION

Using potential outcomes as predictors of treatment activity via strong structural mean models

Stijn VansteelandtEls Goetghebeur

A1 Journal Article in STATISTICA SINICA

2003

A causal proportional hazards estimator for the effect of treatment actually received in a randomized trial with all-or-nothing compliance

Tom LoeysEls Goetghebeur

A1 Journal Article in BIOMETRICS

A sensitivity analysis for causal parameters in structural proportional hazards models

Els GoetghebeurTom Loeys

A2 Journal Article in Statistics and Operations Research Transactions

Causal inference with generalized structural mean models

Stijn VansteelandtEls Goetghebeur

A1 Journal Article in JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

Comment on "Sexual maturation in relation to polychlorinated aromatic hydrocarbons: Sharpe and Skakkebaek's hypothesis revisited"

G MOLENBERGHSC CUYPERSEls GoetghebeurWF PASSCHIERJ PIETERS

A1 Journal Article in ENVIRONMENTAL HEALTH PERSPECTIVES

Methods incorporating compliance in treatment evaluation

J PALMGRENEls Goetghebeur

Bookchapter in Advances in Clinical Trials Biostatistics

Structural accelerated failure time versus proportional hazards modelling for the effects of observed exposures on repeated events in a clinical trial

An VandeboschEls GoetghebeurL VAN DAMME

2002

Baseline information in structural failure time estimators for the effect of observed treatment compliance

Tom LoeysEls Goetghebeur

A1 Journal Article in STATISTICS IN MEDICINE

Beyond intention to treat.

Els GoetghebeurTom Loeys

A1 Journal Article in EPIDEMIOLOGIC REVIEWS

Discussion of Clustered encouragement designs with individual noncompliance: Bayesian inference with randomization, and application to advance directive forms' by Frangacis, Rubin and Zhou.

Els GoetghebeurStijn Vansteelandt

Editorial material

Dose timing information improves the clinical exploratory power of data on patient compliance with antiretroviral drug regimens

Bernard VrijensR GrossEls GoetghebeurE De KlerkJ Urquhart

2001

Accounting for correlation and compliance in cluster randomized trials.

Tom LoeysStijn VansteelandtEls Goetghebeur

A1 Journal Article in STATISTICS IN MEDICINE

Analyzing the sensitivity of generalized linear models to incomplete outcomes via the IDE algorithm

Stijn VansteelandtEls Goetghebeur

A1 Journal Article in JOURNAL OF COMPUTATIONAL AND GRAPHICAL STATISTICS

Life is not perfect: Noncompliance analysis in practice

Els Goetghebeur

Postgraduate Training of Statisticians.

Els Goetghebeur

Sensitivity analysis for incomplete categorical data.

MG KENWARDEls GoetghebeurG MOLENBERGHS

A2 Journal Article in Statistical modelling

Sensitivity analysis for incomplete contingency tables: the Slovenian plebiscite case.

G MOLENBERGHSMG KENWARDEls Goetghebeur

A1 Journal Article in JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES C-APPLIED STATISTICS

Vaginal lavage with chlorhexidine during labour to reduce mother-to-child HIV transmission: clinical trial in Mombasa, Kenya.

P GAILLARDF MWANYUMBAChris VerhofstedePatricia ClaeysV CHOHANEls GoetghebeurK MANDALIYAJ NDINYA-ACHOLAMarleen Temmerman

A1 Journal Article in AIDS

2000

Diagnostic test analyses in search of their gold standard: latent class analyses with random effects.

Els GoetghebeurJan LiinevM BOELAERTPatrick Van Der Stuyft

A1 Journal Article in STATISTICAL METHODS IN MEDICAL RESEARCH

Regression models for disease prevalence with diagnostic tests on pools of serum samples.

Stijn VansteelandtEls GoetghebeurT VERSTRAETEN

A1 Journal Article in BIOMETRICS

Semi-parametric regression analysis of interval censored data.

Els GoetghebeurL RYAN

A2 Journal Article in BIOMETRICS

Semiparametric regression analysis of interval-censored data.

Els GoetghebeurL RYAN

A1 Journal Article in BIOMETRICS

Sensitivity Analysis for Incomplete Data: Ignoring Bounds or Bounding Ignorance?

Stijn VansteelandtEls Goetghebeur

Ten-year trends in CD4 cell counts at HIV and AIDS diagnosis in a London HIV clinic.

PJ EASTERBROOKLM YUEls GoetghebeurF BOAGK MCLEANB GAZZARD

A1 Journal Article in AIDS

Vitamin A and infant mortality: Beyond intention-to-treat in a randomized trial.

P KORHONENTom LoeysEls GoetghebeurJ PALMGREN

A1 Journal Article in LIFETIME DATA ANALYSIS

1999

Adjusting for confouding when estimating a time trend in HIV prevalence based on pooled serum samples

Stijn VansteelandtEls GoetghebeurT Verstraeten

A2 Journal Article in ARCHIVES OF PUBLIC HEALTH

Latent class analysis permits unbiased estimates of the validity of DAT for the diagnosis of visceral leishmaniasis.

M BOELAERTS EL SAFIEls GoetghebeurS GOMES-PEREIRAD LE RAYPatrick Van Der Stuyft

A1 Journal Article in TROPICAL MEDICINE & INTERNATIONAL HEALTH

Missing data perspectives of the fluvoxamine data set: A review.

G MOLENBERGHSEls GoetghebeurSR LIPSITZMG KENWARDE LESAFFREB MICHIELS

A1 Journal Article in STATISTICS IN MEDICINE

Nonrandom missingness in categorical data: Strengths and limitations.

G MOLENBERGHSEls GoetghebeurSR LIPSITZMG KENWARD

A1 Journal Article in AMERICAN STATISTICIAN

Nonrandom missingness in categorical data: strengths and limitations

G MolenberghsEls GoetghebeurS LipsitzM Kenward

A2 Journal Article in THE AMERICAN STATISTICIAN

Practical properties of some structural mean analyses of the effect of compliance in randomized trials.

K FISCHER-LAPPEls Goetghebeur

A1 Journal Article in CONTROLLED CLINICAL TRIALS

Sense and sensitivity when intended data are missing.

Els GoetghebeurG MOLENBERGHSM KENWARD

The impact of compliance in pharmacokinetic studies.

Bernard VrijensEls Goetghebeur

A1 Journal Article in STATISTICAL METHODS IN MEDICAL RESEARCH

The potential of Latent Class Analysis in diagnostic test validation for canine Leishmania infantum infection.

M BOELAERTK AOUNJ LIINEVEls GoetghebeurPatrick Van Der Stuyft

A1 Journal Article in EPIDEMIOLOGY AND INFECTION

1998

Analyzing non-compliance in clinical trials: preface

Els Goetghebeur

Editorial material

Clinical trials comparing two treatment policies: Which aspects of the treatment policies make a difference?

IR WHITEEls Goetghebeur

A1 Journal Article in STATISTICS IN MEDICINE

Estimating the causal effect of compliance on binary outcome in randomized controlled trials.

Els GoetghebeurG MOLENBERGHSJ KATZ

A1 Journal Article in STATISTICS IN MEDICINE

1997

Comparing compliance patterns between randomized treatments

Bernard VrijensEls Goetghebeur

A1 Journal Article in CONTROLLED CLINICAL TRIALS

Contribution of the discussion of the paper. Inference from non-random samples by Copas and Li

Els GoetghebeurK LAPP

A2 Journal Article in JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

Simple fitting algorithms for incomplete categorical data

G MolenberghsEls Goetghebeur

A1 Journal Article in JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

Survival analysis: a self-learning text, David G. Kleinbaum, Springer Series in Statistics, 1996

Els Goetghebeur

The effect of treatment compliance in a placebo-controlled trial: regression with unpaired data

Els GoetghebeurK Lapp

A2 Journal Article in APPLIED STATISTICS

1996

Analysing non-compliance in clinical trials: ethical imperative or mission impossible?

Els GoetghebeurStanley H Shapiro

A1 Journal Article in STATISTICS IN MEDICINE

Analysis of survival data under competing risks with missing cause of death information : application and implications for design

J AndersenEls GoetghebeurL Ryan

Causal inference in placebo-controlled clinical trials with binary outcome and ordered compliance

Els GoetghebeurG MOLENBERGHS

A2 Journal Article in Journal of the American Stastistical Association, 91, pp. 928-934, 1996

Estimating causal parameters in placebo-controlled trials with binary outcome and ordered noncompliance

Els GoetghebeurG MOLENBERGHS

Missing cause of death information in the analysis of survival data

Janet AndersenEls GoetghebeurLouise Ryan

A1 Journal Article in STATISTICS IN MEDICINE

1995

Analysis of competing risks survival data when some failure types are missing

Els GoetghebeurL Ryan

A1 Journal Article in BIOMETRIKA

Detection and estimation of J-shaped risk response relationships

Els GoetghebeurSJ Pocock

A1 Journal Article in JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES A-STATISTICS IN SOCIETY

1990

A modified log rank test for competing risks with missing failure type

Els GoetghebeurRyan Landbrug

A1 Journal Article in BIOMETRIKA

Estimating effectiveness and efficacy at different observed dosing levels with selective noncompliance in a placebo-controlled clinical trial. Proceedings of the 1998 Joint statistical meetings of the American Statistical Association, the Biometrie S ociety and the Institute of Mathematical Statistics.

Els GoetghebeurK LAPP